Citation Impact
Citing Papers
Diabetes and Cardiovascular Disease
1999 Standout
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
2004 StandoutNobel
[44] Insulysin and pitrilysin: Insulin-degrading enzymes of mammals and bacteria
1995
Serum Albumin
1985 Standout
AdipoQ Is a Novel Adipose-specific Gene Dysregulated in Obesity
1996 Standout
Feedback Regulation of β-Arrestin1 Function by Extracellular Signal-regulated Kinases
1999 StandoutNobel
Src-mediated Tyrosine Phosphorylation of Dynamin Is Required for β2-Adrenergic Receptor Internalization and Mitogen-activated Protein Kinase Signaling
1999 StandoutNobel
New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades
2001 StandoutNobel
Sensitive and specific two-site immunoradiometric assays for human insulin, proinsulin, 65-66 split and 32-33 split proinsulins
1989
Thiazolidinediones
2004 Standout
Regulation of Insulin Degradation: Expression of an Evolutionarily Conserved Insulin-Degrading Enzyme Increases Degradation via an Intracellular Pathway
1991
Novel proteases with unusual specificities
1992
RADIOIMMUNOASSAY MAY OVERESTIMATE INSULIN IN NON‐INSULIN‐DEPENDENT DIABETICS
1990
Insulin degradation by Madin-Darby canine kidney cells expressing the insulin receptor
1997 StandoutNobel
Nutritional Regulation of the Insulin-Like Growth Factors*
1994
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Isolation and characterization of an insulin-degrading enzyme from Drosophila melanogaster
1988
Correction of chronic hyperglycemia with vanadate, but not with phlorizin, normalizes in vivo glycogen repletion and in vitro glycogen synthase activity in diabetic skeletal muscle.
1989
Inhibition of Receptor Internalization by Monodansylcadaverine Selectively Blocks p55 Tumor Necrosis Factor Receptor Death Domain Signaling
1999
The Degradation of Apolipoprotein B100 Is Mediated by the Ubiquitin-proteasome Pathway and Involves Heat Shock Protein 70
1997 StandoutNobel
Modulation of insulin action by vanadate: evidence of a role for phosphotyrosine phosphatase activity to alter cellular signaling
1995
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
2002 StandoutNature
Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock
2002 Standout
TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival
2003 Standout
Functional Human Insulin-Degrading Enzyme Can Be Expressed in Bacteria
2000
The β2-Adrenergic Receptor Mediates Extracellular Signal-regulated Kinase Activation via Assembly of a Multi-receptor Complex with the Epidermal Growth Factor Receptor
2000 StandoutNobel
Polycystic Ovary Syndrome
1995 Standout
Glucose-lowering properties of vanadium compounds: Comparison of coordination complexes with maltol or kojic acid as ligands
1997
Multiple metabolic abnormalities in normal glucose tolerant relatives of NIDDM families
1997
Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133
1989 Standout
Stimulation of 125I-transferrin binding and 59Fe uptake in rat adipocytes by vanadate: Treatment time determines apparent tissue sensitivity
1998
Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins
1994 StandoutScience
Diabetes and Atherosclerosis
2002 Standout
Mechanisms of translational control in liver and skeletal muscle
1994
Modulation of Translation Initiation in Rat Skeletal Muscle and Liver in Response to Food Intake
1997
Fasting and postprandial determinants for the occurrence of small dense LDL species in non-insulin-dependent diabetic patients with and without hypertriglyceridaemia: the involvement of insulin, insulin precursor species and insulin resistance
1995
Atomic structure and chemistry of human serum albumin
1992 StandoutNature
Cysteinyl Proteinases and Their Selective Inactivation
1990
Regulation of mammalian translation factors by nutrients
2002
Mechanism of Agonist‐Induced Down‐Regulation and Subsequent Recovery of Muscarinic Acetylcholine Receptors in a Clonal Neuroblastoma X Glioma Hybrid Cell Line
1989
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Mechanisms of fatty acid-induced inhibition of glucose uptake.
1994 Standout
β-Arrestins Regulate Mitogenic Signaling and Clathrin-mediated Endocytosis of the Insulin-like Growth Factor I Receptor
1998 StandoutNobel
Serotonin 5-HT1A Receptor-mediated Erk Activation Requires Calcium/Calmodulin-dependent Receptor Endocytosis
1999 StandoutNobel
Functional and Genomic Analyses Reveal an Essential Coordination between the Unfolded Protein Response and ER-Associated Degradation
2000 Standout
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
1998 StandoutNature
Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes
2003 Standout
Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial
2002 Standout
Insulin-like Growth Factor-I Receptor Internalization Regulates Signaling via the Shc/Mitogen-activated Protein Kinase Pathway, but Not the Insulin Receptor Substrate-1 Pathway
1998
Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells
1984
Faster protein degradation in response to decreases steady state levels of amino acylation of tRNAHis in Chinese hamster ovary cells.
1983
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
1993 Standout
Human insulin production from a novel mini-proinsulin which has high receptor-binding activity
1998
Cyanogen Bromide Cleavage Generates Fragments Suitable for Expressed Protein and Glycoprotein Ligation
2004 StandoutNobel
High Alanine Aminotransferase Is Associated With Decreased Hepatic Insulin Sensitivity and Predicts the Development of Type 2 Diabetes
2002
Sequential processing of insulin by cultured kidney cells.
1995
DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells
2000 StandoutNobel
Peptidolytic monoclonal antibody elicited by a neuropeptide.
1992 StandoutNobel
A direct inhibitory effect of insulin on a cytosolic proteolytic complex containing insulin-degrading enzyme and multicatalytic proteinase.
1994
Initiation of protein synthesis in mammalian cells
1986
Vanadium and diabetes.
1998
Basolateral and apical binding, internalization, and degradation of insulin by cultured kidney epithelial cells
1989
Effect of Bacitracin on Binding and Processing of Insulin by Established Renal Cell Line
1988
Structural features in eukaryotic mRNAs that modulate the initiation of translation.
1991 Standout
A Conserved Biogenesis Pathway for Nucleoporins: Proteolytic Processing of a 186-Kilodalton Precursor Generates Nup98 and the Novel Nucleoporin, Nup96
1999 StandoutNobel
Chronic Subclinical Inflammation as Part of the Insulin Resistance Syndrome
2000 Standout
Functions of Ceramide in Coordinating Cellular Responses to Stress
1996 StandoutScience
Cleavage of vasoactive intestinal peptide at multiple sites by autoantibodies
1991
Alzheimer's Disease: Genes, Proteins, and Therapy
2001 Standout
Regulation of protein turnover in skeletal and cardiac muscle
1991
Essential Role of Insulin in Transcription of the Rat 25,000 Molecular Weight Casein Gene
1984 Science
Regulation of the mannose 6-phosphate/IGF II receptor expression at the cell surface by mannose 6-phosphate, insulin like growth factors and epidermal growth factor.
1989 StandoutNobel
Fusogenic Domains of Golgi Membranes Are Sequestered into Specialized Regions of the Stack that Can Be Released by Mechanical Fragmentation
1999
Kinetic analysis and comparison of uptake, distribution, and excretion of48V-labeled compounds in rats
1998
The Chemistry and Biochemistry of Vanadium and the Biological Activities Exerted by Vanadium Compounds
2004 Standout
Mechanisms of vanadium action: insulin-mimetic or insulin-enhancing agent?
2000
Transfer RNA is an essential component of the ubiquitin- and ATP-dependent proteolytic system.
1985 StandoutNobel
Multihormonal regulation of phosphoenolpyruvate carboxykinase gene transcription. The dominant role of insulin.
1984
Vanadium and diabetes
1998
Microinjection of a protein-tyrosine-phosphatase inhibits insulin action in Xenopus oocytes.
1990 StandoutNobel
Insulin regulation of protein phosphorylation in isolated rat liver nuclear envelopes: potential relationship to mRNA metabolism.
1983
Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.
1990 Standout
Structure of the Receptor for Insulin-Like Growth Factor II: The Puzzle Amplified
1988 Science
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
1987 Standout
Inducible expression and cellular localization of insulin-degrading enzyme in a stably transfected cell line.
1994
Portion-mixing peptide libraries of quenched fluorogenic substrates for complete subsite mapping of endoprotease specificity.
1994 StandoutNobel
Distinct Signaling Events Downstream of mTOR Cooperate To Mediate the Effects of Amino Acids and Insulin on Initiation Factor 4E-Binding Proteins
2005 StandoutNobel
A Macrophage Factor Inhibits Adipocyte Gene Expression: An in Vitro Model of Cachexia
1985 StandoutScienceNobel
A glucagon fragment is responsible for the inhibition of the liver Ca2+ pump by glucagon
1987 Nature
Insulin regulation of protein biosynthesis in differentiated 3T3 adipocytes. Regulation of glyceraldehyde-3-phosphate dehydrogenase.
1985
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction
1987 Standout
Impaired hepatic apolipoprotein B and E translation in streptozotocin diabetic rats.
1992
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Amino acid effects on translational repressor 4E-BP1 are mediated primarily by l -leucine in isolated adipocytes
1998
Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors
2000 StandoutNobel
Carbachol-activated muscarinic (M1 and M3) receptors transfected into Chinese hamster ovary cells inhibit trafficking of endosomes.
1991 StandoutNobel
Works of D E Peavy being referenced
Insulin-Like Effects of Vanadate in Isolated Rat Adipocytes*
1988
Hepatic metabolism of insulin
1988
Insulin degradation products from perfused rat kidney
1989
Degradation products of insulin generated by hepatocytes and by insulin protease.
1988
HPLC Analysis of Insulin Degradation Products From Isolated Hepatocytes: Effects of Inhibitors Suggest Intracellular and Extracellular Pathways
1987
The Degradation of Monoiodotyrosyl Insulin Isomers by Insulin Protease
1984
Correlation of albumin production rates and albumin mRNA levels in livers of normal, diabetic, and insulin-treated diabetic rats.
1978
The role of amino acids in the regulation of protein synthesis in perfused rat liver. I. Reduction in rates of synthesis resulting from amino acid deprivation and recovery during flow-through perfusion.
1982
Time course of changes in albumin synthesis and mRNA in diabetic and insulin-treated diabetic rats
1985
Identification of A chain cleavage sites in intact insulin produced by insulin protease and isolated hepatocytes
1987
High Performance Liquid Chromatographic Analysis of Insulin Degradation by Rat Skeletal Muscle Insulin Protease*
1986
Receptor binding and biological potency of several split forms (conversion intermediates) of human proinsulin. Studies in cultured IM-9 lymphocytes and in vivo and in vitro in rats.
1985
Evidence that Bacitracin Alters Intracellular Insulin Metabolism in Isolated Rat Hepatocytes
1985
Alterations in albumin secretion and total protein synthesis in livers of thyroidectomized rats
1981
Receptor Binding Properties of Monoiodotyrosyl Insulin Isomers Purified by High Performance Liquid Chromatography
1983
Selective Effects of Inhibitors of Hormone Processing on Insulin Action in Isolated Hepatocytes*
1984
Diabetes-induced alterations in liver protein synthesis. Changes in the relative abundance of mRNAs for albumin and other plasma proteins.
1983
The role of amino acids in the regulation of protein synthesis in perfused rat liver. II. Effects of amino acid deficiency on peptide chain initiation, polysomal aggregation, and distribution of albumin mRNA.
1982