Citation Impact
Citing Papers
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
Crystal Structure of a Mammalian Voltage-Dependent Shaker Family K + Channel
2005 StandoutScienceNobel
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Divergent sodium channel defects in familial hemiplegic migraine
2008
Voltage sensor conformations in the open and closed states in rosetta structural models of K + channels
2006 StandoutNobel
Mechanism of functional interaction between potassium channel Kv1.3 and sodium channel NavBeta1 subunit
2017
Transfer of twelve charges is needed to open skeletal muscle Na+ channels.
1995
cAMP‐dependent phosphorylation of the tetrodotoxin‐resistant voltage‐dependent sodium channel SNS
1999
The open pore conformation of potassium channels
2002 StandoutNatureNobel
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
A mutation in segment I-S6 alters slow inactivation of sodium channels
1997
A Model of Voltage Gating Developed Using the KvAP Channel Crystal Structure
2004
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Molecular mechanism for an inherited cardiac arrhythmia
1995 Nature
Molecular cloning and characterization of the rat NMDA receptor
1991 StandoutNature
Energetics of Pore Opening in a Voltage-Gated K+ Channel
2002 StandoutNobel
Stress-induced Apoptosis Associated with Null Mutation of ADAR1 RNA Editing Deaminase Gene
2004
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Functional analysis of an archaebacterial voltage-dependent K+ channel
2003 StandoutNatureNobel
Gain-of-Function Mutations in SCN11A Cause Familial Episodic Pain
2013
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
X-ray structure of a voltage-dependent K+ channel
2003 StandoutNatureNobel
Modulation of Na+channel inactivation by the ?1 subunit: A deletion analysis
1995
Functional Roles of the Extracellular Segments of the Sodium Channel α Subunit in Voltage-dependent Gating and Modulation by β1 Subunits
1999
Restoration of inactivation and block of open sodium channels by an inactivation gate peptide
1994
A Critical Role for the S4-S5 Intracellular Loop in Domain IV of the Sodium Channel α-Subunit in Fast Inactivation
1998
Crystal structure and mechanism of a calcium-gated potassium channel
2002 StandoutNatureNobel
Crystal Structure and Functional Analysis of the HERG Potassium Channel N Terminus
1998 StandoutNobel
N-type Inactivation in the Mammalian Shaker K + Channel Kv1.4
1996
The PDZ Binding Motif of the β1 Adrenergic Receptor Modulates Receptor Trafficking and Signaling in Cardiac Myocytes
2002 StandoutNobel
A Novel Tetrodotoxin-sensitive, Voltage-gated Sodium Channel Expressed in Rat and Human Dorsal Root Ganglia
1997
Voltage-Gated Ion Channels and Electrical Excitability
1998
Tenascin-R Is a Functional Modulator of Sodium Channel β Subunits
1999
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
STRUCTURE AND FUNCTION OF VOLTAGE-GATED ION CHANNELS
1995
Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons
2005
An SCN9A channelopathy causes congenital inability to experience pain
2006 StandoutNature
Interaction between the sodium channel inactivation linker and domain III S4-S5
1997
A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons
1996 StandoutNature
The VGL-Chanome: A Protein Superfamily Specialized for Electrical Signaling and Ionic Homeostasis
2004
Spinal sensory neurons express multiple sodium channel α-subunit mRNAs
1996
Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7
2008 StandoutNatureNobel
Structure and function of voltage‐gated sodium channels at atomic resolution
2013
Proteins that interact with the pore-forming subunits of voltage-gated ion channels
1995
Role in fast inactivation of the IV/S4–S5 loop of the human muscle Na+ channel probed by cysteine mutagenesis
1997
Overview of Molecular Relationships in the Voltage-Gated Ion Channel Superfamily
2005
Diversity of Mammalian Voltage‐Gated Sodium Channels
1999
Voltage gating of ion channels
1994
From Ionic Currents to Molecular Mechanisms
2000 Standout
SCN9A Mutations in Paroxysmal Extreme Pain Disorder: Allelic Variants Underlie Distinct Channel Defects and Phenotypes
2006
Pore properties of rat brain II sodium channels mutated in the selectivity filter domain
1996
How membrane proteins sense voltage
2008
Saxitoxin
2014
Ion Channel Mutations in Periodic Paralysis and Related Myotonic Diseasesa
1993
Ligand-gated ion channels in the brain: The amino acid receptor superfamily
1990
Interaction between Fast and Ultra-slow Inactivation in the Voltage-gated Sodium Channel
2002
Voltage Sensor–Trapping
1998
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Structure and function of the β2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif
1995
Voltage Sensors in Domains III and IV, but Not I and II, Are Immobilized by Na+ Channel Fast Inactivation
1999
The principle of gating charge movement in a voltage-dependent K+ channel
2003 StandoutNatureNobel
Structure and functional expression of a new member of the tetrodotoxin-sensitive voltage-activated sodium channel family from human neuroendocrine cells.
1995
Molecular Determinants of Na+ Channel Function in the Extracellular Domain of the β1 Subunit
1998
Muscarinic Modulation of Sodium Current by Activation of Protein Kinase C in Rat Hippocampal Neurons
1996
Molecular tuning of electroreception in sharks and skates
2018 StandoutNatureNobel
Depth Asymmetries of the Pore-Lining Segments of the Na+ Channel Revealed by Cysteine Mutagenesis
1996
A Critical Role for Transmembrane Segment IVS6 of the Sodium Channel α Subunit in Fast Inactivation
1995
Physiological Characterization of the Yeast Plasma Membrane Outward Rectifying K + Channel, DUK1 (TOK1), In Situ
1998
Slow Inactivation of Na+ Channels
2014
The Extracellular Domain of the β1 Subunit Is Both Necessary and Sufficient for β1-like Modulation of Sodium Channel Gating
1999
SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome
1995 Standout
Tryptophan Scanning of D1S6 and D4S6 C-Termini in Voltage-Gated Sodium Channels
2003
Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel
1992 Science
Patch Clamp Studies on V-type ATPase of Vacuolar Membrane of Haploid Saccharomyces cerevisiae
1999 StandoutNobel
Structure and Function of a Novel Voltage-gated, Tetrodotoxin-resistant Sodium Channel Specific to Sensory Neurons
1996
Movement of the Na+ Channel Inactivation Gate during Inactivation
1996
Cardiac excitation–contraction coupling
2002 StandoutNature
Mapping the receptor site for α-scorpion toxins on a Na + channel voltage sensor
2011
Phosphorylation at a Single Site in the Rat Brain Sodium Channel Is Necessary and Sufficient for Current Reduction by Protein Kinase A
1997
Inactivation defects caused by myotonia-associated mutations in the sodium channel III-IV linker.
1996
RNA Editing by Adenosine Deaminases That Act on RNA
2002
Gating transitions in the selectivity filter region of a sodium channel are coupled to the domain IV voltage sensor
2012
Emergent Ion-Gated Binding of Cationic Host–Guest Complexes within Cationic M12L24 Molecular Flasks
2014 StandoutNobel
Crystallographic insights into sodium-channel modulation by the β4 subunit
2013
Primary Structure And Functional Expression of the 5HT 3 Receptor, A Serotonin-gated Ion Channel
1991 StandoutScienceNobel
Movement of Voltage Sensor S4 in Domain 4 Is Tightly Coupled to Sodium Channel Fast Inactivation and Gating Charge Immobilization
1999
Structure of the Cytoplasmic β Subunit--T1 Assembly of Voltage-Dependent K + Channels
2000 StandoutScienceNobel
Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels
2013
MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans
2000 StandoutNatureNobel
Interaction of voltage-gated sodium channels with the extracellular matrix molecules tenascin-C and tenascin-R
1998
Role of Domain 4 in Sodium Channel Slow Inactivation
2000
Sodium Channel Defects in Myotonia and Periodic Paralysis
1996
Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor
2000 StandoutScienceNobel
The hitchhiker’s guide to the voltage-gated sodium channel galaxy
2015
Immobilizing the Moving Parts of Voltage-Gated Ion Channels
2000
Sodium Channel Activation Gating Is Affected by Substitutions of Voltage Sensor Positive Charges in All Four Domains
1997
Recent Stem Cell Advances: Induced Pluripotent Stem Cells for Disease Modeling and Stem Cell–Based Regeneration
2010 StandoutNobel
A Mutant of TTX-Resistant Cardiac Sodium Channels with TTX-Sensitive Properties
1992 Science
Cation-π Interactions in Chemistry and Biology: A New View of Benzene, Phe, Tyr, and Trp
1996 StandoutScience
Molecular Determinants of β1Subunit-Induced Gating Modulation in Voltage-Dependent Na+Channels
1996
Membrane Structure in Mammalian Astrocytes: A Review of Freeze-Fracture Studies on Adult, Developing, Reactive and Cultured Astrocytes
1981
Neural Science
2000 StandoutNobel
Realistic simulation of the activation of voltage-gated ion channels
2012 StandoutNobel
Molecular Determinants of State-Dependent Block of Na + Channels by Local Anesthetics
1994 Science
The Voltage Sensor in Voltage-Dependent Ion Channels
2000
Structure and Function of Voltage-Dependent Ion Channel Regulatory β Subunits
2002
Saxitoxin
2014
NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy
1998
Sodium Channel Inactivation Is Altered by Substitution of Voltage Sensor Positive Charges
1997
Inactivation and Secondary Structure in the D4/S4-5 Region of the SkM1 Sodium Channel
1998
ION CHANNELS OF NOCICEPTION
1999
Pharmacology of the Na v 1.1 domain IV voltage sensor reveals coupling between inactivation gating processes
2017 StandoutNobel
Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to Eag and cyclic nucleotide-gated channels
1997 StandoutNobel
Neuroscience: Breaking Down Scientific Barriers to the Study of Brain and Mind
2000 StandoutScienceNobel
Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein
2001 StandoutNobel
Emerging Targets in Photopharmacology
2016 StandoutNobel
Molecular Analysis of the Putative Inactivation Particle in the Inactivation Gate of Brain Type IIA Na+ Channels
1997
Widespread A-to-I RNA Editing of Alu-Containing mRNAs in the Human Transcriptome
2004
Whether "Slip-Mode Conductance" Occurs
1999 Science
Enhancement of Replication of RNA Viruses by ADAR1 via RNA Editing and Inhibition of RNA-Activated Protein Kinase
2011
Neuronal Plasticity: Increasing the Gain in Pain
2000 StandoutScience
Glutamine Substitution at Alanine1649 in the S4–S5 Cytoplasmic Loop of Domain 4 Removes the Voltage Sensitivity of Fast Inactivation in the Human Heart Sodium Channel
1998
Direct immunogold labeling of aquaporin-4 in square arrays of astrocyte and ependymocyte plasma membranes in rat brain and spinal cord
1998 StandoutNobel
Interaction of Muscle and Brain Sodium Channels with Multiple Members of the Syntrophin Family of Dystrophin-Associated Proteins
1998
Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype
2011 StandoutNobel
Aquaporin-4 square array assembly: Opposing actions of M1 and M23 isoforms
2003 StandoutNobel
Molecular Dynamics of the Sodium Channel Pore Vary with Gating: Interactions between P-Segment Motions and Inactivation
1999
The moving parts of voltage-gated ion channels
1998
A unique role for the S4 segment of domain 4 in the inactivation of sodium channels.
1996
Molecular Analysis of Potential Hinge Residues in the Inactivation Gate of Brain Type IIA Na+ Channels
1997
Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes
1992 StandoutScienceNobel
Structural basis for gating charge movement in the voltage sensor of a sodium channel
2011 StandoutNobel
Interactions of amino terminal domains of Shaker K channels with a pore blocking site studied with synthetic peptides.
1993
Works of D E Patton being referenced
A peptide segment critical for sodium channel inactivation functions as an inactivation gate in a potassium channel
1993
A voltage-dependent gating transition induces use-dependent block by tetrodotoxin o rat IIA sodium channels expressed in xenopus oocytes
1991
RNA Editing Generates a Diverse Array of Transcripts Encoding Squid Kv2 K+ Channels with Altered Functional Properties
1997
The adult rat brain beta 1 subunit modifies activation and inactivation gating of multiple sodium channel alpha subunits
1994
Primary Structure and Functional Expression of the β 1 Subunit of the Rat Brain Sodium Channel
1992 Science
Fine structural localization of potassium-stimulated rho nitrophenylphosphatase activity in denrites of the cerebral cortex
1978
A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation.
1992
Discrimination of heterogenous mRNAs encoding strychnine-sensitive glycine receptors in Xenopus oocytes by antisense oligonucleotides.
1989
Amino acid residues required for fast Na(+)-channel inactivation: charge neutralizations and deletions in the III-IV linker.
1992