Citation Impact
Citing Papers
Mutations in the mechanotransduction protein PIEZO1 are associated with hereditary xerocytosis
2012
Breast and Ovarian Cancer Risks Due to Inherited Mutations in BRCA1 and BRCA2
2003 StandoutScience
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels
2006 StandoutNobel
Piezo1 ion channel pore properties are dictated by C-terminal region
2015 StandoutNobel
Associations of protein 4.2 with band 3 and ankyrin
2006
Sequence and exon-intron organization of the DNA encoding the alpha I domain of human spectrin. Application to the study of mutations causing hereditary elliptocytosis.
1989 StandoutNobel
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
JAK2 Inhibitors: A Reality? A Hope?
2009
The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration
2019 StandoutNobel
The Clinical Sequelae of Intravascular Hemolysis and Extracellular Plasma Hemoglobin
2005 Standout
JAK Inhibition with Ruxolitinib versus Best Available Therapy for Myelofibrosis
2012 Standout
Alternative isoform regulation in human tissue transcriptomes
2008 StandoutNature
Novel mutations in PIEZO1 cause an autosomal recessive generalized lymphatic dysplasia with non-immune hydrops fetalis
2015
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Hemolytic disease due to membrane ion channel disorders
2004
Structural Analysis of the Plakin Domain of Bullous Pemphigoid Antigen1 (BPAG1) Suggests that Plakins Are Members of the Spectrin Superfamily
2006
Mutations in the extracellular loop of α-rENaC alter sensitivity to amiloride and reactive species
2004
Molecular analysis of insertion/deletion mutations in protein 4.1 in elliptocytosis. I. Biochemical identification of rearrangements in the spectrin/actin binding domain and functional characterizations.
1990 StandoutNobel
Spectrin Oligomerization is Cooperatively Coupled to Membrane Assembly: A Linkage Targeted by Many Hereditary Hemolytic Anemias?
2001
Pathogenesis of polycythaemia vera
1997
Structures of Two Repeats of Spectrin Suggest Models of Flexibility
1999
Pulmonary thromboendarterectomy in a case of hereditary stomatocytosis
2003
Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia
2015 StandoutNobel
Molecular analysis of insertion/deletion mutations in protein 4.1 in elliptocytosis. II. Determination of molecular genetic origins of rearrangements.
1990 StandoutNobel
Evidence That the Penetrance of Mutations at the RP11 Locus Causing Dominant Retinitis Pigmentosa Is Influenced by a Gene Linked to the Homologous RP11 Allele
1997
Spectrin-actin interaction is required for neurite extension in NB 2a/dl neuroblastoma cells
1996
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
2015 Standout
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
c-Src Binds αII Spectrin's Src Homology 3 (SH3) Domain and Blocks Calpain Susceptibility by Phosphorylating Tyr1176
2003
Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels
2013 StandoutNobel
Mechanically Activated Ion Channels
2015 StandoutNobel
Decreased membrane mechanical stability and in vivo loss of surface area reflect spectrin deficiencies in hereditary spherocytosis.
1988 StandoutNobel
Piezos thrive under pressure: mechanically activated ion channels in health and disease
2017 StandoutNobel
Preparation of water-soluble chitosan/heparin complex and its application as wound healing accelerator
2003
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
An Extreme Consequence of Splenectomy in Dehydrated Hereditary Stomatocytosis: Gradual Thrombo‐embolic Pulmonary Hypertension and Lung–Heart Transplantation
2003
Differential control of band 3 lateral and rotational mobility in intact red cells.
1994 StandoutNobel
Molecular pathogenesis of Philadelphia chromosome negative myeloproliferative disorders
2004
Structure of the mechanically activated ion channel Piezo1
2017 StandoutNatureNobel
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
2005 Standout
Expression and purification of recombinant cytoplasmic domain of human erythrocyte band 3 with hexahistidine tag or chitin-binding tag in Escherichia coli
2004
Reductions of erythrocyte membrane viscoelastic coefficients reflect spectrin deficiencies in hereditary spherocytosis.
1988 StandoutNobel
Mapping the Human Erythrocyte β-Spectrin Dimer Initiation Site Using Recombinant Peptides and Correlation of Its Phasing with the α-Actinin Dimer Site
1996
Allele‐specific transcript isoforms in human
2004
Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor
2010 StandoutNobel
Progress and challenges in translating the biology of atherosclerosis
2011 StandoutNature
Superior sagittal sinus thrombosis and pulmonary embolism: a syndrome rediscovered
1992
Structure of the Calmodulin αII-Spectrin Complex Provides Insight into the Regulation of Cell Plasticity
2006 StandoutNobel
Disorders of red cell volume regulation
2013
Cutting to the chase: calpain proteases in cell motility
2002
Linkage of Dominant Hereditary Spherocytosis to the Gene for the Erythrocyte Membrane-Skeleton Protein Ankyrin
1990 StandoutNobel
Nonvalidation of Reported Genetic Risk Factors for Acute Coronary Syndrome in a Large-Scale Replication Study
2007
Severe hemolysis and red cell fragmentation caused by the combination of a spectrin mutation with a thrombotic microangiopathy
1989
Specific Role of the Truncated βIV-Spectrin Σ6 in Sodium Channel Clustering at Axon Initial Segments and Nodes of Ranvier
2006 StandoutNobel
A Gain-of-Function Mutation of JAK2 in Myeloproliferative Disorders
2005 Standout
Thrombosis of the Cerebral Veins and Sinuses
2005 Standout
Free radicals, antioxidant enzymes, and carcinogenesis
1990
Conformational Stabilities of the Structural Repeats of Erythroid Spectrin and Their Functional Implications
2006
Preparation and characteristics of a water‐soluble chitosan–heparin complex
2003
Multiple protein 4.1 isoforms produced by alternative splicing in human erythroid cells.
1988
Hypersensitivity of circulating progenitor cells to megakaryocyte growth and development factor (PEG-rHu MGDF) in essential thrombocythemia
2000
Abnormal spectrin in hereditary elliptocytosis
1986
Hypersensitivity of circulating progenitor cells to megakaryocyte growth and development factor (PEG-rHu MGDF) in essential thrombocythemia
2000
Cell Migration: Integrating Signals from Front to Back
2003 StandoutScience
A partial structural repeat forms the heterodimer self-association site of all beta-spectrins
1994
Hereditary elliptocytosis, spherocytosis and related disorders: Consequences of a deficiency or a mutation of membrane skeletal proteins
1987
Stabilities of folding of clustered, two-repeat fragments of spectrin reveal a potential hinge in the human erythroid spectrin tetramer
2004
Molecular heterogeneity of hereditary pyropoikilocytosis: identification of a second variant of the spectrin alpha-subunit
1983
The Spectrin-Based Membrane Skeleton and Micron-Scale Organization of the Plasma Membrane
1993
Cytoskeletal Protein ABP-280 Directs the Intracellular Trafficking of Furin and Modulates Proprotein Processing in the Endocytic Pathway
1997 StandoutNobel
Location of the human red cell spectrin tetramer binding site and detection of a related “closed” hairpin loop dimer using proteolytic footprinting.
1993
Defective binding of spectrin to ankyrin in a kindred with recessively inherited hereditary elliptocytosis.
1984
Comprehensive analysis of all triple helical repeats in beta-spectrins reveals patterns of selective evolutionary conservation.
2003
Hereditary Elliptocytosis and Related Disorders
1985
Alteration of the erythrocyte membrane skeletal ultrastructure in hereditary spherocytosis, hereditary elliptocytosis, and pyropoikilocytosis
1990 StandoutNobel
Inheritance Pattern and Clinical Response to Splenectomy as a Reflection of Erythrocyte Spectrin Deficiency in Hereditary Spherocytosis
1986 StandoutNobel
Mutant forms of spectrin alpha-subunits in hereditary elliptocytosis.
1987 StandoutNobel
The distribution of erythrocyte phospholipids in hereditary spherocytosis demonstrates a minimal role for erythrocyte spectrin on phospholipid diffusion and asymmetry
1993 StandoutNobel
Hereditary Spherocytosis and Related Disorders
1985
Double inheritance of an alpha I/65 spectrin variant in a child with homozygous elliptocytosis
1986
Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis
2013 StandoutNobel
The structure of the ankyrin-binding site of β-spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties
2009 StandoutNobel
Binding of G protein beta gamma-subunits to pleckstrin homology domains.
1994 StandoutNobel
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation
2018 StandoutNobel
Identification of the hereditary pyropoikilocytosis carrier state
1984
Expression of functional domains of beta G-spectrin disrupts epithelial morphology in cultured cells.
1995
Unique alpha-spectrin mutant in a kindred with common hereditary elliptocytosis.
1987
Disorders of erythrocyte volume homeostasis
2015
Molecular biology of the Rh antigens
1991 StandoutNobel
Distinct variants of erythrocyte protein 4.1 inherited in linkage with elliptocytosis and Rh type in three white families
1988 StandoutNobel
Structural and functional heterogeneity of alpha spectrin mutations involving the spectrin heterodimer self-association site: relationships to hematologic expression of homozygous hereditary elliptocytosis and hereditary pyropoikilocytosis
1990
A new abnormal variant of spectrin in black patients with hereditary elliptocytosis
1985
Full-length sequence of the cDNA for human erythroid beta-spectrin.
1990
Molecular Basis of Hereditary Elliptocytosis Due to Protein 4.1 Deficiency
1986
Partial deficiency of erythrocyte spectrin in hereditary spherocytosis
1985 StandoutNatureNobel
A molecular defect of spectrin in a subset of patients with hereditary elliptocytosis. Alterations in the alpha-subunit domain involved in spectrin self-association.
1984
Spα1/65 hereditary elliptocytosis in North Africa
1986
Chitosan Chemistry and Pharmaceutical Perspectives
2004 Standout
Spectrin and Ankyrin-Based Pathways: Metazoan Inventions for Integrating Cells Into Tissues
2001
Beta spectrin in human skeletal muscle. Tissue-specific differential processing of 3' beta spectrin pre-mRNA generates a beta spectrin isoform with a unique carboxyl terminus
1990
The heterozygous form of 4.1(-) hereditary elliptocytosis [the 4.1(-) trait]
1985
Works of D Dhermy being referenced
Identification of new partners of the epithelial sodium channel alpha subunit
2003
alphaII-Spectrin is an in vitro target for caspase-2, and its cleavage is regulated by calmodulin binding
2004
Hereditary Spherocytosis with Spectrin Deficiency Related to Null Mutations of the β-Spectrin Gene
1998
Glycosaminoglycans enhance human leukemic cell growth in vitro
1994
A nonsense mutation in the erythrocyte band 3 gene associated with decreased mRNA accumulation in a kindred with dominant hereditary spherocytosis.
1996
Properties of normal and mutant polypeptide fragments from the dimer self-association sites of human red cell spectrin
1999
Spontaneous megakaryocyte colony formation in myeloproliferative disorders is not neutralizable by antibodies against IL3, IL6 and GM‐CSF
1994
A common type of the spectrin alpha I 46-50a-kD peptide abnormality in hereditary elliptocytosis and pyropoikilocytosis is associated with a mutation distant from the proteolytic cleavage site. Evidence for the functional importance of the triple helical model of spectrin.
1992
Portal vein thrombosis after splenectomy for hereditary stomatocytosis in childhood
1999
Severe recessive poikilocytic anaemia with a new spectrin α chain variant
1990
A variant of spectrin low‐expression allele αLELY carrying a hereditary elliptocytosis mutation in codon 28
1994
In vitro digestion of spectrin, protein 4.1 and ankyrin by erythrocyte calcium dependent neutral protease (Calpain I)
1990
Spectrin Rouen (beta 220-218), a novel shortened beta-chain variant in a kindred with hereditary elliptocytosis. Characterization of the molecular defect as exon skipping due to a splice site mutation.
1991
Abnormal tryptic peptide from the spectrin α‐chain resulting from α‐ or β‐chain mutations: two genetically distinct forms of the Sp αI/74 variant
1990
Pleiotropic syndrome of dehydrated hereditary stomatocytosis, pseudohyperkalemia, and perinatal edema maps to 16q23-q24.
2000
[Lead encephalopathy with thrombosis of the superior longitudinal sinus].
1985
Red Blood Cell Abnormalities in Hereditary Elliptocytosis and Their Relevance to Variable Clinical Expression
1997
Spectrin self-association site: characterization and study of β-spectrin mutations associated with hereditary elliptocytosis
1998
Spectrin beta-chain variant associated with hereditary elliptocytosis.
1982
Hereditary elliptocytosis: clinical, morphological and biochemical studies of 38 cases.
1986
Hereditary Elliptocytosis with a Spectrin Molecular Defect in a White Patient
1984
Superoxide dismutase, catalase, and glutathione peroxidase in red blood cells from patients with malignant diseases.
1984
Polymorphisms of the Tissue Factor Pathway Inhibitor (TFPI) Gene in Patients With Acute Coronary Syndromes and in Healthy Subjects
1999
Spectrin Nice (beta 220/216): a shortened beta-chain variant associated with an increase of the alpha I/74 fragment in a case of elliptocytosis
1987
Molecular Defect of Spectrin in the Family of a Child with Congenital Hemolytic Poikilocytic Anemia
1984
[Hereditary elliptocytosis in West Africa: frequency and repartition of spectrin variants].
1988
Spectrin Nice (beta 220/216): a shortened beta-chain variant associated with an increase of the alpha I/74 fragment in a case of elliptocytosis
1987
Tyrosine Phosphorylation Regulates Alpha II Spectrin Cleavage by Calpain
2002
Abnormal electrophoretic mobility of spectrin tetramers in hereditary elliptocytosis
1986
Spectrin Tunis (Sp alpha I/78), an elliptocytogenic variant, is due to the CGG----TGG codon change (Arg----Trp) at position 35 of the alpha I domain
1989
[Research on genetic abnormality in the hemolytic form of hereditary elliptocytosis with homozygosity for the spectrin alpha I/74 variant].
1989
Spectrin St Claude, a Splicing Mutation of the Human α-Spectrin Gene Associated With Severe Poikilocytic Anemia
1997
Pathologic and nonpathologic variants of the spectrin molecule in two black families with hereditary elliptocytosis
1985
A deletional frameshift mutation in protein 4.2 gene (allele 4.2 Lisboa) associated with hereditary hemolytic anemia
1995
Identification of three novel spectrin alpha I/74 mutations in hereditary elliptocytosis: further support for a triple-stranded folding unit model of the spectrin heterodimer contact site
1994
A phenomenological difference between membrane skeletal protein complexes isolated from normal and hereditary spherocytosis erythrocytes
1983
Mutations involving the spectrin heterodimer contact site: clinical expression and alterations in specific function.
1993
Epidemiological studies of spectrin mutations related to hereditary elliptocytosis and spectrin polymorphisms in Benin
1996