Citation Impact
Citing Papers
Conserved ATPase and luciferase refolding activities between bacteria and yeast Hsp70 chaperones and modulators
1995
Single molecules of the bacterial actin MreB undergo directed treadmilling motion in Caulobacter crescentus
2006 StandoutNobel
Folding of nascent polypeptide chains in a high molecular mass assembly with molecular chaperones
1994 Nature
Crystal Structure of lac Repressor Core Tetramer and Its Implications for DNA Looping
1995 StandoutScienceNobel
The Dissociation of ATP from hsp70 of Saccharomyces cerevisiae Is Stimulated by Both Ydj1p and Peptide Substrates
1995
Divergent Effects of ATP on the Binding of the DnaK and DnaJ Chaperones to Each Other, or to Their Various Native and Denatured Protein Substrates
1995
COPII-Coated Vesicle Formation Reconstituted with Purified Coat Proteins and Chemically Defined Liposomes
1998 StandoutNobel
Destabilization of the complete protein secondary structure on binding to the chaperone GroEL
1994 StandoutNatureNobel
Partner proteins determine multiple functions of Hsp70
1995
A novel DNA deletion-ligation reaction catalyzed in vitro by a developmentally controlled activity from tetrahymena cells
1989 StandoutNobel
Role of auxilin in uncoating clathrin-coated vesicles
1995 Nature
Successive action of DnaK, DnaJ and GroEL along the pathway of chaperone-mediated protein folding
1992 Nature
The Virus–Chaperone Connection
2001
Coupling of Coat Assembly and Vesicle Budding to Packaging of Putative Cargo Receptors
1999 StandoutNobel
A conserved loop in the ATPase domain of the DnaK chaperone is essential for stable binding of GrpE
1994
The Cysteine String Secretory Vesicle Protein Activates Hsc70 ATPase
1996
The power stroke of the DnaK/DnaJ/GrpE molecular chaperone system 1 1Edited by J.Karn
1997
GroE facilitates refolding of citrate synthase by suppressing aggregation
1991
GrpE-like regulation of the Hsc70 chaperone by the anti-apoptotic protein BAG-1
1997
Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops
1989 NatureNobel
Building a Replisome from Interacting Pieces
1999 StandoutNobel
Purification of tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme
1995 StandoutNobel
Role of the Major Heat Shock Proteins as Molecular Chaperones
1993
Protein Translocation
1999 StandoutNobel
Lumenal proteins of the mammalian endoplasmic reticulum are required to complete protein translocation
1993
The Hsp70 and Hsp60 Chaperone Machines
1998 Standout
The Tim core complex defines the number of mitochondrial translocation contact sites and can hold arrested preproteins in the absence of matrix Hsp70-Tim44
1997
Mge1 functions as a nucleotide release factor for Ssc1, a mitochondrial Hsp70 of Saccharomyces cerevisiae
1997
Nucleotide-induced Conformational Changes in the ATPase and Substrate Binding Domains of the DnaK Chaperone Provide Evidence for Interdomain Communication
1995
Mdj1p, a novel chaperone of the DnaJ family, is involved in mitochondrial biogenesis and protein folding
1994
The karyogamy gene KAR2 and novel proteins are required for ER-membrane fusion
1994 StandoutNobel
Runaway telomere elongation caused by telomerase RNA gene mutations
1995 StandoutNatureNobel
Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex
1991 StandoutNatureNobel
Protein folding in the cell
1992 StandoutNature
Hsp70 chaperones: Cellular functions and molecular mechanism
2005 Standout
Characterization of the Nucleotide Binding Properties and ATPase Activity of Recombinant Hamster BiP Purified from Bacteria
1995
Active unfolding of precursor proteins during mitochondrial protein import
1997
In Vitro Dissociation of BiP-Peptide Complexes Requires a Conformational Change in BiP after ATP Binding but Does Not Require ATP Hydrolysis
1995
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
Unfolded proteins stimulate molecular chaperone Hsc70 ATPase by accelerating ADP/ATP exchange
1992
COPII–cargo interactions direct protein sorting into ER-derived transport vesicles
1998 StandoutNatureNobel
Modulation of the ATPase Activity of the Molecular Chaperone DnaK by Peptides and the DnaJ and GrpE Heat Shock Proteins
1995
Recruitment of Hsp70 chaperones: a crucial part of viral survival strategies
2004
The binding change mechanism for ATP synthase — Some probabilities and possibilities
1993 StandoutNobel
ATP Hydrolysis Is Required for the DnaJ-dependent Activation of DnaK Chaperone for Binding to Both Native and Denatured Protein Substrates
1995
Molecular chaperones in cellular protein folding
1996 StandoutNature
SEC21 is a gene required for ER to Golgi protein transport that encodes a subunit of a yeast coatomer
1992 StandoutNatureNobel
Mechanism of folding chamber closure in a group II chaperonin
2010 StandoutNatureNobel
SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER
1993 StandoutNatureNobel
Developmentally programmed healing of chromosomes by telomerase in tetrahymena
1991 StandoutNobel
Binding of Secretory Precursor Polypeptides to a Translocon Subcomplex Is Regulated by BiP
1997 StandoutNobel
Not all J domains are created equal: Implications for the specificity of Hsp40–Hsp70 interactions
2005
ATPase kinetics of recombinant bovine 70 kDa heat shock cognate protein and its amino-terminal ATPase domain
1994
Molecular Mechanism of Protein Folding in the Cell
2011 StandoutNobel
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
1995 StandoutNobel
Multiple Sequence Versions of the Oxytricha fallax 81‐MAC Alternate Processing Family1
1987
Sec61p and BiP directly facilitate polypeptide translocation into the ER
1992 StandoutNobel
Polymerases and the Replisome: Machines within Machines
1998
The HSP70 chaperone machinery: J proteins as drivers of functional specificity
2010
ATP-induced protein Hsp70 complex dissociation requires K+ but not ATP hydrolysis
1993 Nature
COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast
1995 StandoutNobel
Role of mitochondrial GrpE and phosphate in the ATPase cycle of matrix Hsp70
1997
Translocation gets a push
1994 StandoutNobel
Structure at 2.8 Â resolution of F1-ATPase from bovine heart mitochondria
1994 StandoutNatureNobel
A Bipartite Signaling Mechanism Involved in DnaJ-mediated Activation of the Escherichia coli DnaK Protein
1996
A cycle of binding and release of the DnaK, DnaJ and GrpE chaperones regulates activity of the Escherichia coli heat shock transcription factor sigma32.
1996
Positive cooperativity in the functioning of molecular chaperone GroEL.
1992 StandoutNobel
Eukaryotic homologues of Escherichia coli dnaJ: a diverse protein family that functions with hsp70 stress proteins.
1993
Molecular Chaperones: The Plant Connection
1990 Science
Reconstitution of protein translocation from solubilized yeast membranes reveals topologically distinct roles for BiP and cytosolic Hsc70.
1993 StandoutNobel
Chaperonins facilitate the in vitro folding of monomeric mitochondrial rhodanese
1991
The Escherichia coli heat shock proteins GroEL and GroES modulate the folding of the beta-lactamase precursor.
1990
Selective in vivo rescue by GroEL/ES of thermolabile folding intermediates to phage P22 structural proteins.
1994
DnaK and DnaJ heat shock proteins participate in protein export in Escherichia coli.
1992
Purification and characterization of human DNA damage checkpoint Rad complexes
2001 StandoutNobel
Identification of a regulatory motif in Hsp70 that affects ATPase activity, substrate binding and interaction with HDJ-1.
1995
The Lumenal Domain of Sec63p Stimulates the ATPase Activity of BiP and Mediates BiP Recruitment to the Translocon in Saccharomyces cerevisiae
1997 StandoutNobel
Characterization of chromosome fragmentation in two protozoans and identification of a candidate fragmentation sequence in Euplotes crassus.
1989
Coatomer, Arf1p, and nucleotide are required to bud coat protein complex I-coated vesicles from large synthetic liposomes
1998 StandoutNobel
Topology and functional domains of Sec63p, an endoplasmic reticulum membrane protein required for secretory protein translocation.
1992 StandoutNobel
The ATP hydrolysis-dependent reaction cycle of the Escherichia coli Hsp70 system DnaK, DnaJ, and GrpE.
1994
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
DnaJ Dramatically Stimulates ATP Hydrolysis by DnaK: Insight into Targeting of Hsp70 Proteins to Polypeptide Substrates
1999
Nucleic acid splicing events occur frequently during macronuclear development in the protozoan Oxytricha nova and involve the elimination of unique DNA.
1987
The DNA of ciliated protozoa
1994
Mechanism of clathrin basket dissociation: separate functions of protein domains of the DnaJ homologue auxilin.
1996
Hsp60-independent protein folding in the matrix of yeast mitochondria.
1996
Coat Proteins and Vesicle Budding
1996 StandoutScienceNobel
Multiple interactions of components mediating preprotein translocation across the inner mitochondrial membrane
1997
Hip, a novel cochaperone involved in the eukaryotic hsc70/hsp40 reaction cycle
1995
Chaperone-Assisted Protein Folding Is Critical for Yellow Fever Virus NS3/4A Cleavage and Replication
2016 StandoutNobel
Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct.
1996 StandoutNobel
BiP and Sec63p are required for both co- and posttranslational protein translocation into the yeast endoplasmic reticulum.
1995 StandoutNobel
Molecular Matchmakers
1993 StandoutScienceNobel
The Escherichia coli DnaK chaperone, the 70-kDa heat shock protein eukaryotic equivalent, changes conformation upon ATP hydrolysis, thus triggering its dissociation from a bound target protein
1991
The human cytosolic molecular chaperones hsp90, hsp70 (hsc70) and hdj-1 have distinct roles in recognition of a non-native protein and protein refolding.
1996
Topology and Functional Domains of Sec63p, an Endoplasmic Reticulum Membrane Protein Required for Secretory Protein Translocation
1992 StandoutNobel
A yeast DnaJ homologue, Scj1p, can function in the endoplasmic reticulum with BiP/Kar2p via a conserved domain that specifies interactions with Hsp70s.
1995
The NH2-terminal 108 amino acids of the Escherichia coli DnaJ protein stimulate the ATPase activity of DnaK and are sufficient for lambda replication.
1994
Telomeres and Their Synthesis
1990 StandoutScienceNobel
Characterization of a stable, reactivatable complex between chaperonin 60 and mitochondrial rhodanese.
1992
A zinc finger-like domain of the molecular chaperone DnaJ is involved in binding to denatured protein substrates.
1996
Cooperation of GroEL/GroES and DnaK/DnaJ heat shock proteins in preventing protein misfolding in Escherichia coli.
1992
Interaction of Hsp70 chaperones with substrates
1997
Protein Sorting by Transport Vesicles
1996 StandoutScienceNobel
Crystal Structure of the Nucleotide Exchange Factor GrpE Bound to the ATPase Domain of the Molecular Chaperone DnaK
1997 Science
hsp70-protein complexes. Complex stability and conformation of bound substrate protein.
1994
Genetic interactions between KAR2 and SEC63, encoding eukaryotic homologues of DnaK and DnaJ in the endoplasmic reticulum.
1993
Regulation of Hsp70 function by a eukaryotic DnaJ homolog.
1992
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs.
1995 StandoutNobel
The role of the GrpE homologue, Mge1p, in mediating protein import and protein folding in mitochondria.
1995
Mechanism of regulation of Hsp70 chaperones by DnaJ cochaperones
1999
A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome.
1993 StandoutNobel
Isolation of Components of the Chloroplast Protein Import Machinery
1994 StandoutScienceNobel
Kinetics of Molecular Chaperone Action
1994 Science
GrpE Accelerates Nucleotide Exchange of the Molecular Chaperone DnaK with an Associative Displacement Mechanism
1997
Nucleation of COPII Vesicular Coat Complex by Endoplasmic Reticulum to Golgi Vesicle SNAREs
1998 StandoutScienceNobel
DnaK, DnaJ and GrpE form a cellular chaperone machinery capable of repairing heat-induced protein damage.
1993
Identification of heat shock protein hsp70 homologues in chloroplasts.
1990
Molecular Biology of Prion Diseases
1991 StandoutScienceNobel
Structural Analysis of Substrate Binding by the Molecular Chaperone DnaK
1996 Science
Structure and function of telomeres
1991 StandoutNatureNobel
Interaction between BiP and Sec63p is required for the completion of protein translocation into the ER of Saccharomyces cerevisiae.
1995 StandoutNobel
Post-translational protein translocation: not all hsc70s are created equal
1996
Identification of a Caulobacter crescentus operon encoding hrcA, involved in negatively regulating heat-inducible transcription, and the chaperone gene grpE
1996
Mitochondrial protein import: biochemical and genetic evidence for interaction of matrix hsp70 and the inner membrane protein MIM44.
1994
Cyclophilin 20 Is Involved in Mitochondrial Protein Folding in Cooperation with Molecular Chaperones Hsp70 and Hsp60
1995
Mutations within the nucleotide binding site of immunoglobulin-binding protein inhibit ATPase activity and interfere with release of immunoglobulin heavy chain.
1993
Nucleoprotein structures initiating DNA replication, transcription, and site-specific recombination.
1990
The DnaJ chaperone catalytically activates the DnaK chaperone to preferentially bind the sigma 32 heat shock transcriptional regulator.
1995
Works of D. D. Ang being referenced
The Escherichia coli groE chaperonins.
1990
Initiation of lambda DNA replication with purified host- and bacteriophage-encoded proteins: the role of the dnaK, dnaJ and grpE heat shock proteins.
1989
Escherichia coli DnaJ and GrpE heat shock proteins jointly stimulate ATPase activity of DnaK.
1991
Mitochondrial GrpE Is Present in a Complex with hsp70 and Preproteins in Transit across Membranes
1994
Function of the GrpE heat shock protein in bidirectional unwinding and replication from the origin of phage lambda.
1993
The heat-shock-regulated grpE gene of Escherichia coli is required for bacterial growth at all temperatures but is dispensable in certain mutant backgrounds
1989
Mobile elements bounded by C4A4 telomeric repeats in oxytricha fallax
1985
Isolation and characterization of point mutations in the Escherichia coli grpE heat shock gene
1994
Physical interactions between bacteriophage and Escherichia coli proteins required for initiation of lambda DNA replication.
1990
Isolation and characterization of dnaJ null mutants of Escherichia coli
1990
The grpE protein of Escherichia coli. Purification and properties.
1987
Escherichia coli grpE gene codes for heat shock protein B25.3, essential for both lambda DNA replication at all temperatures and host growth at high temperature
1986
Biological role and regulation of the universally conserved heat shock proteins.
1991