Citation Impact
Citing Papers
α-Hemolysin from Escherichia coli uses endogenous amplification through P2X receptor activation to induce hemolysis
2009
IFN-β Increases Listeriolysin O-Induced Membrane Permeabilization and Death of Macrophages
2008
Pleiotropic Coupling of G Protein-coupled Receptors to the Mitogen-activated Protein Kinase Cascade
1999 StandoutNobel
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
The UPEC Pore-Forming Toxin α-Hemolysin Triggers Proteolysis of Host Proteins to Disrupt Cell Adhesion, Inflammatory, and Survival Pathways
2012
Acute lymphoblastic leukaemia: a model for the pharmacogenomics of cancer therapy
2006
Toward a Personalized Medicine Approach to the Management of Inflammatory Bowel Disease
2014
Ulcerative Colitis
2011 Standout
Regulation of the ERK Subgroup of MAP Kinase Cascades Through G Protein-Coupled Receptors
1997
Dietary Intake and Bioavailability of Polyphenols
2000 Standout
Impact of Smoking, Smoking Cessation, and Genetic Polymorphisms on CYP1A2 Activity and Inducibility
2011
Role of platelet-derived growth factors in physiology and medicine
2008 Standout
ERM proteins and merlin: integrators at the cell cortex
2002 Standout
The interindividual differences in the 3-demthylation of caffeine alias CYP1A2 is determined by both genetic and environmental factors.
2002
Type I interferons in infectious disease
2015 Standout
A novel intronic mutation, 2988G>A, with high predictivity for impaired function of cytochrome P450 2D6 in white subjects*1
2004
Regulation of tyrosine kinase cascades by G-protein-coupled receptors
1999 StandoutNobel
G Protein-coupled Receptors Mediate Two Functionally Distinct Pathways of Tyrosine Phosphorylation in Rat 1a Fibroblasts
1997 StandoutNobel
In Vitro and In Vivo Evaluations of Cytochrome P450 1A2 Interactions with Duloxetine
2008
Expression of an antibody Fv fragment in myeloma cells
1988 StandoutNobel
CYP Gene Polymorphisms and Early Menarche
2001
Gβγ Subunits Mediate Mitogen-activated Protein Kinase Activation by the Tyrosine Kinase Insulin-like Growth Factor 1 Receptor
1995 StandoutNobel
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
2016 Standout
Src family protein tyrosine kinases and cellular signal transduction pathways
1995
Crohn's disease
2016 Standout
Essential Role for G Protein-coupled Receptor Endocytosis in the Activation of Mitogen-activated Protein Kinase
1998 StandoutNobel
β-Arrestin1 Interacts with the Catalytic Domain of the Tyrosine Kinase c-SRC
2000 StandoutNobel
What is the mammalian dentate gyrus good for?
2008 StandoutNobel
Phenotypic polymorphism and gender‐related differences of CYP1A2 activity in a Chinese population
2000
Diagnostics of Inflammatory Bowel Disease
2007
β-Arrestin1 Mediates Insulin-like Growth Factor 1 (IGF-1) Activation of Phosphatidylinositol 3-Kinase (PI3K) and Anti-apoptosis
2003 StandoutNobel
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
2001 Standout
The effect of smoking and cytochrome P450 CYP1A2 genetic polymorphism on clozapine clearance and dose requirement
2003
Genetic polymorphism of CYP1A2 increases the risk of myocardial infarction
2004
THE CHOLINERGIC ‘PITFALL’: ACETYLCHOLINE, A UNIVERSAL CELL MOLECULE IN BIOLOGICAL SYSTEMS, INCLUDING HUMANS
1999
Thrombin Stimulates Phosphorylation of Insulin-like Growth Factor-1 Receptor, Insulin Receptor Substrate-1, and Phospholipase C-γ1 in Rat Aortic Smooth Muscle Cells
1995
Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2
2009
Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors
1997 StandoutNobel
Acetaminophen‐induced acute liver failure
2005 Standout
Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry
2004
Bacterial pore-forming toxins: The (w)hole story?
2007
Human Cytochrome P450 Enzymes: A Status Report Summarizing Their Reactions, Substrates, Inducers, and Inhibitors
1997
Organizing the cell cortex: the role of ERM proteins
2010 Standout
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease
2008 Standout
Urinary tract infections: epidemiology, mechanisms of infection and treatment options
2015 Standout
Activation and Translocation of c-Src to the Cytoskeleton by Both Platelet-derived Growth Factor and Epidermal Growth Factor
1995
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
2013 Standout
Pathway-Targeted Pharmacogenomics of CYP1A2 in Human Liver
2010
The Current State of Knowledge on Age, Sex, and Their Interactions on Clinical Pharmacology
2007
Evaluation of probe drugs and pharmacokinetic metrics for CYP2D6 phenotyping
2007
The inflammatory reflex
2002 StandoutNature
Phosphorylation of Threonine 558 in the Carboxyl-terminal Actin-binding Domain of Moesin by Thrombin Activation of Human Platelets
1995
Regulation of protein tyrosine kinases in platelets
1994
Role of c-Src Tyrosine Kinase in G Protein-coupled Receptorand Gβγ Subunit-mediated Activation of Mitogen-activated Protein Kinases
1996 StandoutNobel
Gβγ Subunits Mediate Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor
1997 StandoutNobel
Non-neuronal acetylcholine, a locally acting molecule, widely distributed in biological systems: Expression and function in humans
1998
Functional characterization of four allelic variants of human cytochrome P450 1A2
2003
Dosage‐dependent switch from G protein‐coupled to G protein‐independent signaling by a GPCR
2006 StandoutNobel
Developmental Pharmacology — Drug Disposition, Action, and Therapy in Infants and Children
2003 Standout
Gender differences in drug responses
2006
Synthesis and Function of 3-Phosphorylated Inositol Lipids
2001 Standout
Properties of beta-adrenergic receptors of cultured mammalian cells. Interaction of receptors with a guanine nucleotide-binding protein in membranes prepared from L6 myoblasts and from wild-type and cyc- S49 lymphoma cells.
1985
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Review article: recent advances in pharmacogenetics and pharmacokinetics for safe and effective thiopurine therapy in inflammatory bowel disease
2016
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
Genetic and environmental factors associated with variation of human xenobiotic glucuronidation and sulfation.
1997
Policy: NIH to balance sex in cell and animal studies
2014 StandoutNature
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
Prolactin (PRL) and Its Receptor: Actions, Signal Transduction Pathways and Phenotypes Observed in PRL Receptor Knockout Mice
1998 Standout
Diffusible, nonfibrillar ligands derived from Aβ 1–42 are potent central nervous system neurotoxins
1998 Standout
Implicit Solvation Models: Equilibria, Structure, Spectra, and Dynamics
1999 Standout
Pharmacokinetics of monoclonal immunoglobulin G1, F(ab')2, and Fab' in mice.
1986
G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein.
1995 StandoutNobel
Integrins and Signal Transduction Pathways: the Road Taken
1995 StandoutScience
Activation of Src family kinase activity by the G protein-coupled thrombin receptor in growth-responsive fibroblasts.
1994
A mutation of the beta 2-adrenergic receptor impairs agonist activation of adenylyl cyclase without affecting high affinity agonist binding. Distinct molecular determinants of the receptor are involved in physical coupling to and functional activation of Gs.
1990 StandoutNobel
The Inflammasomes: Guardians of the Body
2009 Standout
The Effects of Plant Flavonoids on Mammalian Cells:Implications for Inflammation, Heart Disease, and Cancer
2000 Standout
2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation
2015 Standout
Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human
1999 Standout
Uptake of nitric oxide synthase inhibitors by macrophage RAW 264.7 cells
1994
The Timing of Normal Puberty and the Age Limits of Sexual Precocity: Variations around the World, Secular Trends, and Changes after Migration
2003 Standout
Electrostatics and the Membrane Association of Src: Theory and Experiment
1998
Cytotoxic Necrotizing Factor 1 and Hemolysin from Uropathogenic Escherichia coli Elicit Different Host Responses in the Murine Bladder
2012
SCY-635, a Novel Nonimmunosuppressive Analog of Cyclosporine That Exhibits Potent Inhibition of Hepatitis C Virus RNA ReplicationIn Vitro
2009
Interindividual Variability in Acetaminophen Glucuronidation by Human Liver Microsomes: Identification of Relevant Acetaminophen UDP-Glucuronosyltransferase Isoforms
2001
Comprehensive analysis of the genetic factors determining expression and function of hepatic CYP2D6
2001
Drug Interactions With Phosphodiesterase-5 Inhibitors Used for the Treatment of Erectile Dysfunction or Pulmonary Hypertension
2010
Pharmacogenetic Determinants of Codeine Induction by Rifampin: The Impact on Codeine’s Respiratory, Psychomotor and Miotic Effects
1997
Arginine metabolism: nitric oxide and beyond
1998 Standout
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release
2017 StandoutNobel
Enteral absorption and bioavailability in children in relation to age
1980
Variation in CYP1A2 Activity and its Clinical Implications: Influence of Environmental Factors and Genetic Polymorphisms
2008
Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor
1999 Standout
Works of D. Brockmeier being referenced
Comprehensive analysis of thiopurine S-methyltransferase phenotype–genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants
2004
Listeriolysin of Listeria monocytogenes forms Ca2+-permeable pores leading to intracellular Ca2+ oscillations
2002
Evidence for muscarinic receptors in endothelial cells from combined functional and binding studies
1990
Interactions of sildenafil and tacrolimus in men with erectile dysfunction after kidney transplantation
2001
Characterization of cyclosporine a uptake in human erythrocytes
1994
The influence of environmental and genetic factors on CYP2D6, CYP1A2 and UDP-glucuronosyltransferases in man using sparteine, caffeine, and paracetamol as probes
1994
A distribution study of CYP1A2 phenotypes among smokers and non-smokers in a cohort of healthy Caucasian volunteers
1998
Substrate affinity of the protein tyrosine kinase pp60c-src is increased on thrombin stimulation of human platelets
1993
Mean residence time.
1986
Properties of agonist binding at the?-adrenoceptor of the rat reticulocyte
1982
Why Escherichia coli α‐hemolysin induces calcium oscillations in mammalian cells‐the pore is on its own
2006
A rotating iterative procedure (RIP) for estimating hybrid constants in multi-compartment analysis on desk computers
1977