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Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
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Taking Cell-Matrix Adhesions to the Third Dimension
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Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet
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Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia: a Southwest Oncology Group Study.
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AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis
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Successful Allogeneic Transplantation of T-Cell–Depleted Bone Marrow from Closely HLA-Matched Unrelated Donors
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Molecular Basis of Oculocutaneous Albinism.
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1993
Chromosome Aberrations, Gene Mutations and Expression Changes, and Prognosis in Adult Acute Myeloid Leukemia
2006
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MLL translocations, histone modifications and leukaemia stem-cell development
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Prognostic Impact of Acute Myeloid Leukemia Classification: Importance of Detection of Recurring Cytogenetic Abnormalities and Multilineage Dysplasia on Survival
2003
Genetic instabilities in human cancers
1998 StandoutNature
Phenotypic conversion of T lymphoblastic lymphoma to acute biphenotypic leukemia composed of lymphoblasts and myeloblasts. Molecular genetic evidence of the same clonal origin.
1988 StandoutNobel
A genetic model for colorectal tumorigenesis
1990 Standout
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
2008 Standout
Mutations and Treatment Outcome in Cytogenetically Normal Acute Myeloid Leukemia
2008
Cancer Epigenetics: From Mechanism to Therapy
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Influence of new molecular prognostic markers in patients with karyotypically normal acute myeloid leukemia: recent advances
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The multiple roles of CUX1: Insights from mouse models and cell-based assays
2008
Clinicopathological features of acute undifferentiated leukaemia with a stem cell phenotype
1990
The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells
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Angelman syndrome
1995
Acute biphenotypic leukaemia: immunophenotypic and cytogenetic analysis
1993
Cdx4 and Menin Co-Regulate Hoxa9 Expression in Hematopoietic Cells
2006
Clinical Implications of Novel Mutations in Epigenetic Modifiers in AML
2011
Prognostic impact of c-KIT mutations in core binding factor leukemias: an Italian retrospective study
2005
In Childhood Acute Lymphoblastic Leukemia, Blasts at Different Stages of Immunophenotypic Maturation Have Stem Cell Properties
2008
Loss of genetic material is more common than gain in acute myeloid leukemia with complex aberrant karyotype: A detailed analysis of 125 cases using conventional chromosome analysis and fluorescence in situ hybridization including 24‐color FISH
2002
Sequential multiagent chemotherapy is not superior to high-dose cytarabine alone as postremission intensification therapy for acute myeloid leukemia in adults under 60 years of age: Cancer and Leukemia Group B Study 9222
2004
Acute myeloid leukaemia
2006
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Cancer genes and the pathways they control
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Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia
2011 Standout
A white blood cell index as the main prognostic factor in t(8;21) acute myeloid leukemia (AML): a survey of 161 cases from the French AML Intergroup
2002
Cell-matrix contact structures
2001
Acute Myeloid Leukemia and the Position of Autologous Stem Cell Transplantation
2007
Transient expression of the NG2 proteoglycan by a subpopulation of activated macrophages in an excitotoxic hippocampal lesion
2001
Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease
1999
Incidence and prognostic impact of c-Kit, FLT3, and Ras gene mutations in core binding factor acute myeloid leukemia (CBF-AML)
2006
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
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Graft-versus-host disease
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Biology and management of relapsed acute myeloid leukaemia
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Tumour heterogeneity and cancer cell plasticity
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11q23 balanced chromosome aberrations in treatment‐related myelodysplastic syndromes and acute leukemia: Report from an International Workshop†
2002
Characterization of fusion partner genes in 114 patients with de novo acute myeloid leukemia and MLL rearrangement
2005
Hereditary Colorectal Cancer
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Granulocyte–Macrophage Colony-Stimulating Factor after Initial Chemotherapy for Elderly Patients with Primary Acute Myelogenous Leukemia
1995
Primary vs. secondary neoplasia-associated chromosomal abnormalities—balanced rearrangements vs. genomic imbalances?
1996
The clinical significance of cytogenetic abnormalities in acute myeloid leukaemia
2001
Use of Gene-Expression Profiling to Identify Prognostic Subclasses in Adult Acute Myeloid Leukemia
2004
Genetic alterations in leukemias and lymphomas: Impressive progress and continuing complexity
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Additional chromosome abnormalities confer worse prognosis in acute promyelocytic leukaemia
1997
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
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Growth factors in acute myeloid leukaemia
2001
Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow
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Severity of chronic graft-versus-host disease: association with treatment-related mortality and relapse
2002
Decision-making and quality of life in older adults with acute myeloid leukemia or advanced myelodysplastic syndrome
2004
Analysis of prognostic factors for the outcome of marrow transplantation or further chemotherapy for patients with acute nonlymphocytic leukemia in first remission.
1989 StandoutNobel
Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461)
2002
The value of allogeneic bone marrow transplant in patients with acute myeloid leukaemia at differing risk of relapse: results of the UK MRC AML 10 trial
2002
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
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NF-κB functions as a tumour promoter in inflammation-associated cancer
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Simultaneous Inference in General Parametric Models
2008 Standout
DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia
2010
Wilms tumor 1 gene mutations are associated with a higher risk of recurrence in young adults with acute myeloid leukemia
2009
Molecular Diagnosis of the Hematologic Cancers
2003
Efficacy of allogeneic hematopoietic stem cell transplantation depends on cytogenetic risk for acute myeloid leukemia in first disease remission
2005
Underrepresentation of Patients 65 Years of Age or Older in Cancer-Treatment Trials
1999 Standout
MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors
2004
Prognostic impact of karyotype and immunologic phenotype in 125 adult patients with de novo AML
1992
Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22
1984 Standout
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
2010 StandoutNobel
Prognostic impact of WT1 mutations in cytogenetically normal acute myeloid leukemia: a study of the German-Austrian AML Study Group
2009
Comparison of Cytogenetic and Molecular Genetic Detection of t(8;21) and inv(16) in a Prospective Series of Adults With De Novo Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study
2001
I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development
2010 StandoutNobel
THE CRITICAL ROLE OF CHROMOSOME TRANSLOCATIONS IN HUMAN LEUKEMIAS
1998
Pretreatment cytogenetics add to other prognostic factors predicting complete remission and long-term outcome in patients 60 years of age or older with acute myeloid leukemia: results from Cancer and Leukemia Group B 8461
2006
Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring
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Checkpoints: Controls That Ensure the Order of Cell Cycle Events
1989 StandoutScienceNobel
Clustering of aberrations to specific chromosomes in human neoplasms
2009
MLD according to the WHO classification in AML has no correlation with age and no independent prognostic relevance as analyzed in 1766 patients
2007
Overexpression of the ETS-Related Gene, ERG, Predicts a Worse Outcome in Acute Myeloid Leukemia With Normal Karyotype: A Cancer and Leukemia Group B Study
2005
Multicopper Oxidases and Oxygenases
1996 Standout
Acute Myeloid Leukemia
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Antitumor Antibiotics: Bleomycin, Enediynes, and Mitomycin
2005 Standout
6-Thioguanine, Cytarabine, and Daunorubicin (TAD) and High-Dose Cytarabine and Mitoxantrone (HAM) for Induction, TAD for Consolidation, and Either Prolonged Maintenance by Reduced Monthly TAD or TAD-HAM-TAD and One Course of Intensive Consolidation by Sequential HAM in Adult Patients at All Ages With De Novo Acute Myeloid Leukemia (AML): A Randomized Trial of the German AML Cooperative Group
2003
Clinical and laboratory characteristics of acute leukemia with the 4;11 translocation
1986
Prognostic Importance of MN1 Transcript Levels, and Biologic Insights From MN1-Associated Gene and MicroRNA Expression Signatures in Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study
2009
New chromosomal translocations correlate with specific immunophenotypes of childhood acute lymphoblastic leukemia
1984
Expression of breast cancer resistance protein in blast cells from patients with acute leukemia
2000
Cytogenetics and age are major determinants of outcome in intensively treated acute myeloid leukemia patients older than 60 years: results from AMLSG trial AML HD98-B
2006
The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
2009 Standout
Acute Myeloid Leukemia in the Elderly: Assessment of Multidrug Resistance (MDR1) and Cytogenetics Distinguishes Biologic Subgroups With Remarkably Distinct Responses to Standard Chemotherapy. A Southwest Oncology Group Study
1997
The Chromosomal Basis of Human Neoplasia
1983 Science
Adult Patients With De Novo Acute Myeloid Leukemia and t(9; 11)(p22; q23) Have a Superior Outcome to Patients With Other Translocations Involving Band 11q23: A Cancer and Leukemia Group B Study
1997
Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification?
2006
Amplification and Rearrangement of Hu- ets -1 in Leukemia and Lymphoma with Involvement of 11q23
1986 Science
BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: a Cancer and Leukemia Group B Study
2003
Expression of breast cancer resistance protein in blast cells from patients with acute leukemia
2000
Prognostic Factors and Outcome of Core Binding Factor Acute Myeloid Leukemia Patients With t(8;21) Differ From Those of Patients With inv(16): A Cancer and Leukemia Group B Study
2005
Adverse Prognostic Significance of KIT Mutations in Adult Acute Myeloid Leukemia With inv(16) and t(8;21): A Cancer and Leukemia Group B Study
2006
Postremission therapy in older patients with de novo acute myeloid leukemia: a randomized trial comparing mitoxantrone and intermediate-dose cytarabine with standard-dose cytarabine
2001
Patients With t(8;21)(q22;q22) and Acute Myeloid Leukemia Have Superior Failure-Free and Overall Survival When Repetitive Cycles of High-Dose Cytarabine Are Administered
1999
Leukemic Stem Cells in Childhood High-Risk ALL/t(9;22) and t(4;11) Are Present in Primitive Lymphoid-Restricted CD34+CD19− Cells
2005
Phenotypic analysis of acute lymphoblastic leukemia (ALL) cells which are classified as non-T non-B and negative for common ALL antigen
1985
The Clonal Evolution of Tumor Cell Populations
1976 StandoutScience
Fused transcript of abl and bcr genes in chronic myelogenous leukaemia
1985 StandoutNature
Inflammatory Blockade Restores Adult Hippocampal Neurogenesis
2003 StandoutScience
Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc
1984 StandoutNatureNobel
CEBPA Mutations in Younger Adults With Acute Myeloid Leukemia and Normal Cytogenetics: Prognostic Relevance and Analysis of Cooperating Mutations
2004
Chromosomal Abnormalities in Leukemia and Lymphoma: Clinical and Biological Significance
1986
FLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myeloid leukemia lacking FLT3 internal tandem duplications
2007
The prognostic and functional role of microRNAs in acute myeloid leukemia
2010
Activation of a translocated c-myc gene: role of structural alterations in the upstream region.
1984 StandoutNobel
The gene encoding the T-cell surface protein T4 is located on human chromosome 12.
1986 StandoutNobel
Double Induction Containing Either Two Courses or One Course of High-Dose Cytarabine Plus Mitoxantrone and Postremission Therapy by Either Autologous Stem-Cell Transplantation or by Prolonged Maintenance for Acute Myeloid Leukemia
2006
Prognosis of inv(16)/t(16;16) acute myeloid leukemia (AML): a survey of 110 cases from the French AML Intergroup
2003
Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum
2011 StandoutScience
Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: a study of the AML Study Group Ulm
2002
Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations
2005
Population-based age-specific incidences of cytogenetic subgroups of acute myeloid leukemia.
2005
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Detailed studies on expression and function of CD19 surface determinant by using B43 monoclonal antibody and the clinical potential of anti- CD19 immunotoxins
1988
G 1 Events and Regulation of Cell Proliferation
1989 StandoutScience
Mast cells and mastocytosis
2008
Hereditary nonpolyposis colorectal cancer (lynch syndromes I and II). II. Biomarker studies
1985
Distinctive demography, biology, and outcome of acute myeloid leukemia and myelodysplastic syndrome in children with Down syndrome: Children's Cancer Group Studies 2861 and 2891.
1998
Molecular pathogenesis of the chromosome 16 inversion in the M4Eo subtype of acute myeloid leukemia [see comments]
1995
Effect of priming with granulocyte–macrophage colony-stimulating factor in younger adults with newly diagnosed acute myeloid leukemia: a trial by the Acute Leukemia French Association (ALFA) Group
2007
Long-term disease-free survivors with cytogenetically normal acute myeloid leukemia and MLL partial tandem duplication: a Cancer and Leukemia Group B study
2007
The Importance of Diagnostic Cytogenetics on Outcome in AML: Analysis of 1,612 Patients Entered Into the MRC AML 10 Trial
1998 Standout
Adult acute myeloid leukaemia: update on treatment
1999
Detection of leukemic cells in the CD34+CD38− bone marrow progenitor population in children with acute lymphoblastic leukemia
2001
Amplification of the MLL gene on double minutes, a homogeneously staining region, and ring chromosomes in five patients with acute myeloid leukemia or myelodysplastic syndrome
2000
Abnormal Cytogenetics at Date of Morphologic Complete Remission Predicts Short Overall and Disease-Free Survival, and Higher Relapse Rate in Adult Acute Myeloid Leukemia: Results From Cancer and Leukemia Group B Study 8461
2004
Disclosure of Candidate Genes in Acute Myeloid Leukemia With Complex Karyotypes Using Microarray-Based Molecular Characterization
2006
Management of Acute Myelogenous Leukemia in the Elderly
2003
Repetitive Cycles of High-Dose Cytarabine Benefit Patients With Acute Myeloid Leukemia and inv(16)(p13q22) or t(16;16)(p13;q22): Results from CALGB 8461
2004
The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
2016 Standout
Long-term survival of patients with acute myeloid leukemia
1997
Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative Oncology Group study
2000
IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study
2010
Acute myeloid leukemia M4 with bone marrow eosinophilia (M4Eo) and inv(16)(p13q22) exhibits a specific immunophenotype with CD2 expression
1993
KIT-D816 mutations in AML1-ETO-positive AML are associated with impaired event-free and overall survival
2005
Individual Patient Data–Based Meta-Analysis of Patients Aged 16 to 60 Years With Core Binding Factor Acute Myeloid Leukemia: A Survey of the German Acute Myeloid Leukemia Intergroup
2004
Wilms’ Tumor 1 Gene Mutations Independently Predict Poor Outcome in Adults With Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study
2008
Comparison of Cytogenetic and Molecular Cytogenetic Detection of Chromosome Abnormalities in 240 Consecutive Adult Patients With Acute Myeloid Leukemia
2002
Prognostic Impact of Acute Myeloid Leukemia Classification
2003
Sense and nonsense of high-dose cytarabine for acute myeloid leukemia
2013
Karyotype in acute myeloblastic leukemia: prognostic significance for bone marrow transplantation in first remission: a European Group for Blood and Marrow Transplantation study. Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT).
1997
Serum lactic dehydrogenase level has prognostic value in childhood acute lymphoblastic leukemia
1985
The Mouse Pink-Eyed Dilution Gene: Association with Human Prader-Willi and Angelman Syndromes
1992 Science
Mutation of the E6-AP Ubiquitin Ligase Reduces Nuclear Inclusion Frequency While Accelerating Polyglutamine-Induced Pathology in SCA1 Mice
1999 StandoutNobel
Works of D Arthur being referenced
Cytogenetically aberrant cells are present in the CD34+CD33−38−19− marrow compartment in children with acute lymphoblastic leukemia
1997
Activity of imatinib in systemic mastocytosis with chronic basophilic leukemia and a PRKG2-PDGFRB fusion
2007
Cigarette Smoking and Risk of Acute Leukemia: Associations With Morphology and Cytogenetic Abnormalities in Bone Marrow
1993
The clinical significance of karyotype in acute myelogenous leukemia
1989
Molecular rearrangements of the MLL gene are present in most cases of infant acute myeloid leukemia and are strongly correlated with monocytic or myelomonocytic phenotypes.
1994
Long-term survival in acute myelogenous leukemia
1994
The human homologue of rat NG2, a chondroitin sulfate proteoglycan, is not expressed on the cell surface of normal hematopoietic cells but is expressed by acute myeloid leukemia blasts from poor-prognosis patients with abnormalities of chromosome band 11q23
1996
Acute leukemia associated with the t(4;11) chromosome rearrangement: ultrastructural and immunologic characteristics
1982
Chromosomal abnormalities in acute lymphoblastic leukemia.
1981
Hypopigmentation in the Prader-Willi syndrome.
1987
Frequency of prolonged remission duration after high-dose cytarabine intensification in acute myeloid leukemia varies by cytogenetic subtype.
1998
Heterogeneity of cultured leukemic lymphoid progenitor cells from B cell precursor acute lymphoblastic leukemia (ALL) patients.
1987
ALLOGENEIC BONE MARROW TRANSPLANTATION WITH RELATED DONORS OTHER THAN HLA MLC-MATCHED SIBLINGS, AND THE USE OF ANTITHYMOCYTE GLOBULIN, PREDNISONE, AND METHOTREXATE FOR PROPHYSAXIS OF GRAFT-VERSUS-HOST DISEASE
1985
Rearrangement of ALL1 (MLL) in acute myeloid leukemia with normal cytogenetics.
1998
Partial tandem duplication of ALL1 as a recurrent molecular defect in acute myeloid leukemia with trisomy 11.
1996
Hereditary adenocarcinoma of the colon in childhood: Association with the cancer family syndrome
1978
Relapse after non-T-cell-depleted allogeneic bone marrow transplantation for chronic myelogenous leukemia: early transplantation, use of an unrelated donor, and chronic graft-versus- host disease are protective
1996