Citation Impact
Citing Papers
A BOILED‐Egg To Predict Gastrointestinal Absorption and Brain Penetration of Small Molecules
2016 Standout
The gut microbiota influences blood-brain barrier permeability in mice
2014 Standout
TEER Measurement Techniques for In Vitro Barrier Model Systems
2015 Standout
Engineering precision nanoparticles for drug delivery
2020 Standout
Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis
2017 Standout
Parkinson disease
2017 Standout
A Systematic Comparison of the Properties of Clinically Used Angiotensin II Type 1 Receptor Antagonists
2013
The Blood-Brain Barrier
2013
Structure and function of the blood–brain barrier
2009 Standout
Species differences in drug transporters and implications for translating preclinical findings to humans
2012
Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions
2014 Standout
PLGA-based nanoparticles: An overview of biomedical applications
2012 Standout
Piperacillin penetration into tissue of critically ill patients with sepsis—Bolus versus continuous administration?
2009
Albumin–drug interaction and its clinical implication
2013 Standout
Indolin-2-one p38α inhibitors II: Lead optimisation
2011
Delivery of therapeutic agents to the central nervous system: the problems and the possibilities
2004
The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME–Tox)
2008
Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders
2018 Standout
The Role of Canalicular ABC Transporters in Cholestasis
2014
Lung cancer: current therapies and new targeted treatments
2016 Standout
Unbound Drug Concentration in Brain Homogenate and Cerebral Spinal Fluid at Steady State as a Surrogate for Unbound Concentration in Brain Interstitial Fluid
2008
The blood-brain barrier: an engineering perspective
2013
Role of P-Glycoprotein in Pharmacokinetics
2003
Targeting multidrug resistance in cancer
2006 Standout
Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises
2011 Standout
Clinical Relevance of P-Glycoprotein in Drug Therapy
2003
Development, maintenance and disruption of the blood-brain barrier
2013 Standout
Design and fabrication of magnetic nanoparticles for targeted drug delivery and imaging
2009 Standout
A within-trial cost-effectiveness analysis of primary care referral to a commercial provider for weight loss treatment, relative to standard care—an international randomised controlled trial
2012 Standout
Towards Better BBB Passage Prediction Using an Extensive and Curated Data Set
2015
Clinical Pharmacokinetics and Pharmacodynamics of Tacrolimus in Solid Organ Transplantation
2004 Standout
Lactoferrin-conjugated PEG–PLA nanoparticles with improved brain delivery: In vitro and in vivo evaluations
2008
Coexistence of passive and carrier-mediated processes in drug transport
2010
Transport of opioids from the brain to the periphery by P-glycoprotein: peripheral actions of central drugs
2001
Drug delivery via the blood–brain barrier
2001
The use of spirocyclic scaffolds in drug discovery
2014 Standout
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
2013 StandoutNobel
PROTAC targeted protein degraders: the past is prologue
2022 Standout
Targeting the brain with PEG–PLGA nanoparticles modified with phage-displayed peptides
2011
Nonlinear intestinal pharmacokinetics of mitemcinal, the first acid-resistant non-peptide motilin receptor agonist, in rats
2007 StandoutNobel
Drug–Drug Interaction Studies: Regulatory Guidance and An Industry Perspective
2013
Pharmacokinetic and Pharmacodynamic Implications of P‐glycoprotein Modulation
2001
Nature and consequences of mammalian brain and CSF efflux transporters: four decades of progress
2009
Synthetic glycopeptides and glycoproteins as tools for biology
2004 StandoutNobel
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
The effect of plasma protein binding on in vivo efficacy: misconceptions in drug discovery
2010
The Pathobiology of Vascular Dementia
2013 Standout
Establishment and Characterization of the Transformants Stably-Expressing MDR1 Derived from Various Animal Species in LLC-PK1
2006
Peripherally acting CB1-receptor antagonist: the relative importance of central and peripheral CB1 receptors in adiposity control
2009
Evidence-based approach to assess passive diffusion and carrier-mediated drug transport
2012
Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates
2014
Developmental Pharmacology — Drug Disposition, Action, and Therapy in Infants and Children
2003 Standout
Quantitative Correlation of Physical and Chemical Properties with Chemical Structure: Utility for Prediction
2010
Historical Perspective of Traditional Indigenous Medical Practices: The Current Renaissance and Conservation of Herbal Resources
2014 Standout
pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures
2015 Standout
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals
2014 Standout
Azole-Based Energetic Salts
2011 Standout
Molecular Properties That Influence the Oral Bioavailability of Drug Candidates
2002 Standout
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
2020 Standout
Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment
2013 Standout
Mechanisms of Cancer Drug Resistance
2002 Standout
Discovery and Evaluation of Clinical Candidate AZD3759, a Potent, Oral Active, Central Nervous System-Penetrant, Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
2015
Penetration of Drugs through the Blood-Cerebrospinal Fluid/Blood-Brain Barrier for Treatment of Central Nervous System Infections
2010 Standout
Computational Prediction of Blood-Brain Barrier Permeability Using Decision Tree Induction
2012
ETCM: an encyclopaedia of traditional Chinese medicine
2018 Standout
Structural Modifications that Alter the P-Glycoprotein Efflux Properties of Compounds
2012
Levodopa therapy for Parkinson disease
2016
Dendrimer Advances for the Central Nervous System Delivery of Therapeutics
2013
Natural Products as Sources of New Drugs from 1981 to 2014
2016 Standout
CNS Drug Design: Balancing Physicochemical Properties for Optimal Brain Exposure
2014
Applications of Fluorine in Medicinal Chemistry
2015 Standout
Predicting Efflux Ratios and Blood-Brain Barrier Penetration from Chemical Structure: Combining Passive Permeability with Active Efflux by P-Glycoprotein
2012
Enkephalin Glycopeptide Analogues Produce Analgesia with Reduced Dependence Liability
2000
Physiology of Microglia
2011 Standout
Works of Cuiping Chen being referenced
Extensive Biliary Excretion of the Model Opioid Peptide [D-PEN2,5] Enkephalin in Rats
1997
Do We Need to Optimize Plasma Protein and Tissue Binding in Drug Discovery?
2011
P-Glycoprotein Limits the Brain Penetration of Nonsedating but not Sedating H1-Antagonists
2003
Utility of Mdr1-Gene Deficient Mice in Assessing the Impact of P-glycoprotein on Pharmacokinetics and Pharmacodynamics in Drug Discovery and Development
2003
Enhanced Antinociception of the Model Opioid Peptide [D-Penicillamine2,5] Enkephalin by P-Glycoprotein Modulation
1999
Use of a Physiologically Based Pharmacokinetic Model to Study the Time to Reach Brain Equilibrium: An Experimental Analysis of the Role of Blood-Brain Barrier Permeability, Plasma Protein Binding, and Brain Tissue Binding
2005
Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration
2006
Utility of a Novel Oatp1b2 Knockout Mouse Model for Evaluating the Role of Oatp1b2 in the Hepatic Uptake of Model Compounds
2008
Pharmacokinetics of Levodopa/Carbidopa Delivered From Gastric‐Retentive Extended‐Release Formulations in Patients With Parkinson's Disease
2011
Progress in Brain Penetration Evaluation in Drug Discovery and Development
2008
DEVELOPMENT OF A COMPUTATIONAL APPROACH TO PREDICT BLOOD-BRAIN BARRIER PERMEABILITY
2004
Altered Disposition and Antinociception of [d-Penicillamine2,5] Enkephalin in mdr1a-Gene-Deficient Mice
1998
Gastroretentive carbidopa/levodopa, DM‐1992, for the treatment of advanced Parkinson's disease
2015
Strategies to optimize brain penetration in drug discovery.
2005