Citation Impact
Citing Papers
Guidelines for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack
2014 Standout
Forced chromatin looping raises fetal hemoglobin in adult sickle cells to higher levels than pharmacologic inducers
2016
Fetal Hemoglobin, Sickling, and Sickle Cell Disease
1990
The Molecular Genetics of Human Hemoglobin
1984
ICA-17043, a novel Gardos channel blocker, prevents sickled red blood cell dehydration in vitro and in vivo in SAD mice
2003
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Long-Term Engraftment and Fetal Globin Induction upon BCL11A Gene Editing in Bone-Marrow-Derived CD34 + Hematopoietic Stem and Progenitor Cells
2017
Minimally differentiated erythroleukaemia (AML M6 Variant'): a rare subset of AML distinct from AML M6
1995
How Malaria Has Affected the Human Genome and What Human Genetics Can Teach Us about Malaria
2005
Ischemia and reperfusion—from mechanism to translation
2011 Standout
Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity
2020 StandoutNobel
The Clinical Sequelae of Intravascular Hemolysis and Extracellular Plasma Hemoglobin
2005 Standout
Cell Biology of Heme
1999
Pathogenesis and Treatment of Sickle Cell Disease
1997
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
The Influence of Macromolecular Crowding and Macromolecular Confinement on Biochemical Reactions in Physiological Media
2001 Standout
Pulmonary Hypertension as a Risk Factor for Death in Patients with Sickle Cell Disease
2004
The β-Thalassemias
1999 Standout
Effect of Hydroxyurea on the Frequency of Painful Crises in Sickle Cell Anemia
1995 Standout
High-resolution structure of the Shigella type-III secretion needle by solid-state NMR and cryo-electron microscopy
2014 StandoutNobel
Solid‐State NMR Spectroscopy on Complex Biomolecules
2010
NOVEL TREATMENT OPTIONS IN THE SEVERE β‐GLOBIN DISORDERS
1995
Detrimental effects of adenosine signaling in sickle cell disease
2010
Microfluidic organs-on-chips
2014 Standout
Sickle Cell Hemoglobin Polymerization
1990
Reductions of erythrocyte membrane viscoelastic coefficients reflect spectrin deficiencies in hereditary spherocytosis.
1988 StandoutNobel
Gene Silencing in Cancer in Association with Promoter Hypermethylation
2003 Standout
Prevention of a First Stroke by Transfusions in Children with Sickle Cell Anemia and Abnormal Results on Transcranial Doppler Ultrasonography
1998 Standout
Updated Clinical Classification of Pulmonary Hypertension
2013 Standout
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
2003 Standout
DNA Methylation Inhibitors in the Treatment of Leukemias, Myelodysplastic Syndromes and Hemoglobinopathies: Clinical Results and Possible Mechanisms of Action
2000
Sickle-cell disease
2010 Standout
Identification of the haemoglobin scavenger receptor
2001 StandoutNature
The present and future role of microfluidics in biomedical research
2014 StandoutNature
Retroviral vectors displaying functional antibody fragments
1993 StandoutNobel
Homology requirements for unequal crossing over in humans.
1991 StandoutNobel
Mortality In Sickle Cell Disease -- Life Expectancy and Risk Factors for Early Death
1994 Standout
Comparative studies of phenothiazine derivatives for their effects on swelling of normal and sickle erythrocytes
1993
Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice
2002 Standout
Treatment of Sickle Cell Anemia with Hydroxyurea and Erythropoietin
1990
The fundamental role of epigenetic events in cancer
2002 Standout
The Human Condition—A Molecular Approach
2014 StandoutNobel
Position-independent, high-level expression of the human β-globin gene in transgenic mice
1987 Standout
Seeding “one-dimensional crystallization” of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?
1993 Standout
Extended Therapy with Intravenous Arginine Butyrate in Patients with β-Hemoglobinopathies
1995
Pulmonary Complications of Sickle Cell Disease
2012
Repair of thalassemic human β-globin mRNA in mammalian cells by antisense oligonucleotides
1996
Beyond hemoglobin polymerization: the red blood cell membrane and sickle disease pathophysiology
1991
Cation transport and volume regulation in sickle red blood cells
1993
Advances in thalassemia research
1984
Effects of 5-aza-2′-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease
2003
A gene deletion ending within a complex array of repeated sequences 3' to the human beta-globin gene cluster.
1986 StandoutNobel
[38] RNA polymerase II transcription in vitro
1991 StandoutNobel
Hydroxyurea: effects on hemoglobin F production in patients with sickle cell anemia [see comments]
1992
Nucleotide sequence of 16-kilobase pairs of DNA 5' to the human epsilon-globin gene.
1985 StandoutNobel
Is there a threshold level of fetal hemoglobin that ameliorates morbidity in sickle cell anemia?
1984
Direct Gene Transfer into Mouse Muscle in Vivo
1990 StandoutScience
Proliferation of multipotent hematopoietic cells controlled by a truncated erythropoietin receptor transgene.
1996 StandoutNobel
Effects of thalassemia and microcytosis on the hematologic and vasoocclusive severity of sickle cell anemia
1984
Nitric oxide therapy in sickle cell disease
2001
Enantioselective Synthesis of Di- and Tri-Arylated All-Carbon Quaternary Stereocenters via Copper-Catalyzed Allylic Arylations with Organolithium Compounds
2016 StandoutNobel
Macromolecular crowding and confinement in cells exposed to hypertonicity
1994
Hydroxyurea as an Alternative to Blood Transfusions for the Prevention of Recurrent Stroke in Children With Sickle Cell Disease
1999
Marrow Transplantation for Thalassemiaa
1985 StandoutNobel
Induction of fetal hemoglobin production in subjects with sickle cell anemia by oral sodium phenylbutyrate
1994
The distribution of erythrocyte phospholipids in hereditary spherocytosis demonstrates a minimal role for erythrocyte spectrin on phospholipid diffusion and asymmetry
1993 StandoutNobel
A ChineseGγ+(Aγδβ)0thalassemia deletion: comparison to other deletions in the human β-globin gene cluster and sequence analysis of the breakpoints
1985 StandoutNobel
On the induction of fetal hemoglobin by butyrates: in vivo and in vitro studies with sodium butyrate and comparison of combination treatments with 5-AzaC and AraC
1989
Treatment of sickle cell anemia with 5-azacytidine results in increased fetal hemoglobin production and is associated with nonrandom hypomethylation of DNA around the gamma-delta-beta-globin gene complex.
1983
Hematopoietic stem cells with controllable tEpoR transgenes have a competitive advantage in bone marrow transplantation
2000 StandoutNobel
Hemoglobin variants and activity of the (K+Cl-) cotransport system in human erythrocytes
1992
Hydroxyurea as an Alternative to Blood Transfusions for the Prevention of Recurrent Stroke in Children With Sickle Cell Disease
1999
The cellular basis for different fetal hemoglobin levels among sickle cell individuals with two, three, and four alpha-globin genes
1987
Sustained induction of fetal hemoglobin by pulse butyrate therapy in sickle cell disease.
1999
Hemoglobin S gelation and sickle cell disease
1987
A Common Human β Globin Splicing Mutation Modeled in Mice
1998 StandoutNobel
Genetic analysis of the 5-azacytidine sensitivity of Escherichia coli K-12
1987 StandoutNobel
Progress Toward Human Gene Therapy
1989 Science
Accurate initiation at RNA polymerase II promoters in extracts from Saccharomyces cerevisiae.
1987 StandoutNobel
Genetic Dissection of Complex Traits
1994 StandoutScience
A Biophysical Indicator of Vaso-occlusive Risk in Sickle Cell Disease
2012
Unusually large von Willebrand factor multimers increase adhesion of sickle erythrocytes to human endothelial cells under controlled flow.
1987
Hydroxyurea: effects on hemoglobin F production in patients with sickle cell anemia [see comments]
1992
Effects of 5-azacytidine and its 2′-deoxyderivative on cell differentiation and DNA methylation
1985
CpG-rich islands and the function of DNA methylation
1986 StandoutNature
Retroviral transfer of the recombinant human erythropoietin receptor gene into single hematopoietic stem/progenitor cells from human cord blood increases the number of erythropoietin-dependent erythroid colonies
1996
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
Correction of a human beta S-globin gene by gene targeting.
1991 StandoutNobel
Static and dynamic rigidities of normal and sickle erythrocytes. Major influence of cell hemoglobin concentration.
1984
Locus control region-A gamma transgenic mice: a new model for studying the induction of fetal hemoglobin in the adult
1991
Clinical diversity of sickle cell anemia: Genetic and cellular modulation of disease severity
1983
Endothelial cells in physiology and in the pathophysiology of vascular disorders.
1998 Standout
Pathophysiology of the Aquaporin Water Channels
1996 StandoutNobel
Functional Significance of Cell Volume Regulatory Mechanisms
1998 Standout
The effect of volume occupancy upon the thermodynamic activity of proteins: some biochemical consequences
1983
The silent carrier allele: β thalassemia without a mutation in the β-globin gene or its immediate flanking regions
1984 StandoutNobel
The World Health Organization (WHO) classification of the myeloid neoplasms
2002 Standout
Changes in DNA Methylation in Neoplasia: Pathophysiology and Therapeutic Implications
2001
Cell Biology of Heme
1999
Delay Time of Hemoglobin S Polymerization Prevents Most Cells from Sickling in Vivo
1987 Science
Works of CT Noguchi being referenced
Polymerization of sickle cell hemoglobin at arterial oxygen saturation impairs erythrocyte deformability.
1988
Levels of Fetal Hemoglobin Necessary for Treatment of Sickle Cell Disease
1988
Hemoglobin S polymerization: primary determinant of the hemolytic and clinical severity of the sickling syndromes
1985
Cloning of the human erythropoietin receptor gene
1991
Hemoglobin S polymerization: primary determinant of the hemolytic and clinical severity of the sickling syndromes
1985
Variation in fetal hemoglobin parameters and predicted hemoglobin S polymerization in sickle cell children in the first two years of life: Parisian Prospective Study on Sickle Cell Disease
1994
5-Azacytidine increases gamma-globin synthesis and reduces the proportion of dense cells in patients with sickle cell anemia
1983
The intracellular polymerization of sickle hemoglobin and its relevance to sickle cell disease
1981
Molecular and cellular pathogenesis of hemoglobin SC disease.
1982
13C NMR quantitation of polymer in deoxyhemoglobin S gels.
1979
Hydroxyurea increases fetal hemoglobin in cultured erythroid cells derived from normal individuals and patients with sickle cell anemia or beta-thalassemia
1993
Hemin-induced acceleration of hemoglobin production in immature cultured erythroid cells: preferential enhancement of fetal hemoglobin
1995
5-Azacytidine increases gamma-globin synthesis and reduces the proportion of dense cells in patients with sickle cell anemia
1983
Polymerization in erythrocytes containing S and non-S hemoglobins
1984