Standout Papers
Citation Impact
Citing Papers
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression
2005 StandoutNobel
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors
2022 StandoutNobel
Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
2024 StandoutNobel
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2007 Standout
Functional diversity of helper T lymphocytes
1996 StandoutNature
Airways inflammationin asthma and chronic bronchitis
1996
Different cytokine patterns in bronchial biopsies in asthma and chronic bronchitis
1996
Tachykinin-independent effects of capsaicin on smooth muscle in human isolated bronchi.
1997
Tobacco Smoke Promotes Lung Tumorigenesis by Triggering IKKβ- and JNK1-Dependent Inflammation
2010
Epithelium dysfunction in asthma
2007
Antigen challenge induces pulmonary airway eosinophil accumulation and airway hyperreactivity in sensitized guinea‐pigs: the effect of anti‐asthma drugs
1990
Animal Models of Cigarette Smoke-Induced COPD*
2002
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Airway structure and inflammatory cells in fatal attacks of asthma
1996
The Role of Neural Inflammation in Asthma and Chronic Obstructive Pulmonary Disease
2003
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
2006 Standout
A research method to induce and examine a mild exacerbation of asthma by withdrawal of inhaled corticosteroid
1992
Systemic inflammation in chronic obstructive pulmonary disease
2003
Neural regulation of innate immunity: a coordinated nonspecific host response to pathogens
2006 Standout
Bronchial Hyperresponsiveness and Level of Exposure in Occupational Asthma due to Western Red Cedar ( Thuja plicata ): Serial Observations before and after Development of Symptoms
1992
The distribution of eosinophils and lymphocytes in the large and small airways of asthmatics
1997
Mechanisms linking obesity with cardiovascular disease
2006 StandoutNature
The capsaicin receptor: a heat-activated ion channel in the pain pathway
1997 StandoutNatureNobel
Neutralizing Granulocyte/Macrophage Colony–Stimulating Factor Inhibits Cigarette Smoke–induced Lung Inflammation
2010
Inhaled beclomethasone versus placebo for chronic asthma
1999
Animal models of chronic obstructive pulmonary disease
2008
The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease
2004 Standout
Depletion of Tumor-Associated Macrophages Slows the Growth of Chemically Induced Mouse Lung Adenocarcinomas
2014
Immunology of asthma and chronic obstructive pulmonary disease
2008
A capsaicin-receptor homologue with a high threshold for noxious heat
1999 StandoutNatureNobel
A Randomized, Double-blind, Placebo-controlled Study of Tumor Necrosis Factor-α Blockade in Severe Persistent Asthma
2009
Oral corticosteroids in patients admitted to hospital with exacerbations of chronic obstructive pulmonary disease: a prospective randomised controlled trial
1999
Interleukin-17 in sputum correlates with airway hyperresponsiveness to methacholine
2003
The role of glutathione-S-transferase in anti-cancer drug resistance
2003
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
1999 StandoutNatureNobel
Plasma exudation and solute absorption across the airway mucosa
1993
Activated T-Lymphocytes and Macrophages in Bronchial Mucosa of Subjects with Chronic Bronchitis
1993
Contractile effects of bradykinin on the isolated human small bronchus.
1994
The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli
1998 StandoutNobel
Bronchial biopsy evidence for leukocyte infiltration and upregulation of leukocyte-endothelial cell adhesion molecules 6 hours after local allergen challenge of sensitized asthmatic airways.
1994
Airway Mucosal Inflammation Even in Patients with Newly Diagnosed Asthma
1993
Eosinophilic and neutrophilic inflammation in asthma, chronic bronchitis, and chronic obstructive pulmonary disease
1993
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
Asthma: defining of the persistent adult phenotypes
2006
Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications
2006 Standout
The eosinophil and bronchial asthma: Current understanding
1990
Glutathione S-transferase mediates an ageing response to mitochondrial dysfunction
2015
Natural killer cell functions mediated by the neuropeptide substance P
2003
Alveolar Macrophages as Orchestrators of COPD
2004
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
Effect of glutathione-S-transferase M1 and P1 genotypes on xenobiotic enhancement of allergic responses: randomised, placebo-controlled crossover study
2004
The development of allergic inflammation
2008 StandoutNature
Compensation for Occupational Asthma in Quebec
1990
Ruthenium red as a capsaicin antagonist
1991
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Mediators of Chronic Obstructive Pulmonary Disease
2004
Immunity, Inflammation, and Cancer
2010 Standout
Pulmonary Inflammation and Emphysema
2007
Basophils in airway disease
2002
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
Promotion of Lung Carcinogenesis by Chronic Obstructive Pulmonary Disease–Like Airway Inflammation in a K-ras–Induced Mouse Model
2008
Airway permeability
1995
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Asthma phenotypes: the evolution from clinical to molecular approaches
2012 Standout
Inflammatory cells and mediators in bronchial lavage of patients with chronic obstructive pulmonary disease
1998
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Capsazepine: a competitive antagonist of the sensory neurone excitant capsaicin
1992
Potential therapeutic targets for neurokinin-1 receptor antagonists
2004
Global strategy for asthma management and prevention: GINA executive summary
2007 Standout
Activated T-lymphocytes and eosinophils in the bronchial mucosa in isocyanate-induced asthma
1992
Resistance of quiescent and proliferating airway epithelial cells to H2O2challenge
2007
Immunoglobulin E-mediated Increase in Vascular Permeability Correlates with Eosinophilic Inflammation
1993
The Role of Oxidative Stress in the Pathogenesis??of COPD
2005
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
The pharmacology of the efferent function of sensory nerves.
1991
Analysis of Post-translational CCR8 Modifications and Their Influence on Receptor Activity
2004
Activation of CD4+ T cells, increased TH2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma
1993
Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: Comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness
1991
Tachykinins, sensory nerves, and asthma—an overview
1995
Airway inflammation after removal from the causal agent in occupational asthma due to high and low molecular weight agents
1994
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
2004 StandoutNatureNobel
Acute effects of cigarette smoke on inflammation and oxidative stress: a review
2004
Carbon monoxide in biology and medicine
2004
Inflammation, Atherosclerosis, and Coronary Artery Disease
2005 Standout
Inflammation in bronchial biopsies of subjects with chronic bronchitis: inverse relationship of CD8+ T lymphocytes with FEV1.
1997
Elastin fragments drive disease progression in a murine model of emphysema
2006
The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease
2004 Standout
TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents
2006 StandoutNobel
Eosinophils: Biology and Role in Disease
1995
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
2010 StandoutNature
Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia
2000 StandoutNature
The Role of Oxidative Stress in Chronic Obstructive Pulmonary Disease
2004
Heme oxygenase-1 and carbon monoxide in pulmonary medicine
2003
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
2003 StandoutNature
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
Allergen exposure induces the activation of allergen‐specific Th2 cells in the airway mucosa of patients with allergic respiratory disorders
1993
Identification of granulocyte subtype–selective receptors and ion channels by using a high-density oligonucleotide probe array
2004
Long-term effectiveness of pulmonary rehabilitation in patients with chronic airway obstruction
1999
Chronic obstructive pulmonary disease: molecular and cellularmechanisms
2003
The role of T lymphocytes in the pathogenesis of asthma
2003
Airways Remodeling Is a Distinctive Feature of Asthma and Is Related to Severity of Disease
1997
Eosinophilic Airway Inflammation during Exacerbation of Asthma and Its Treatment with Inhaled Corticosteroid
1991
Effects of Glucocorticoids on Humoral and Cellular Immunity and on Airway Inflammation in Patients with Steroid-Dependent Intractable Asthma
1993
Asthma
2000 Standout
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2001 Standout
Cigarette Smoking Impairs the Therapeutic Response to Oral Corticosteroids in Chronic Asthma
2003
Airway Inflammation in Occupational Asthma
1994
Effects of Smoking Cessation on Lung Function and Airway Inflammation in Smokers with Asthma
2006
Theophylline
2003
The Development of Emphysema in Cigarette Smoke-exposed Mice Is Strain Dependent
2004
A Long-term Study of the Antiinflammatory Effect of Low-dose Budesonide Plus Formoterol versus High-dose Budesonide in Asthma
2000
Increases in Activated T Lymphocytes, Eosinophils, and Cytokine mRNA Expression for Interleukin-5 and Granulocyte/Macrophage Colony-stimulating Factor in Bronchial Biopsies after Allergen Inhalation Challenge in Atopic Asthmatics
1993
Transforming Growth Factor- β Expression in Mucosal Biopsies in Asthma and Chronic Bronchitis
1997
Neutrophilic Inflammation in Severe Persistent Asthma
1999
Inflammatory Reaction in Pulmonary Muscular Arteries of Patients with Mild Chronic Obstructive Pulmonary Disease
1999
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Biopsy Neutrophilia, Neutrophil Chemokine and Receptor Gene Expression in Severe Exacerbations of Chronic Obstructive Pulmonary Disease
2003
Increased Levels of Elastase and α 1 -Antitrypsin in Sputum of Asthmatic Patients
1998
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
2006 StandoutScience
Number and activity of inflammatory cells in bronchoalveolar lavage fluid in asthma and their relation to airway responsiveness.
1988
Toxic Potential of Materials at the Nanolevel
2006 StandoutScience
Potential therapeutic targets for neurokinin-1 receptor antagonists
2004
Regulation of mucin expression in respiratory diseases
2009
Beclomethasone for asthma in children: effects on linear growth
1999
Human Eosinophils Induce Mucin Production in Airway Epithelial Cells Via Epidermal Growth Factor Receptor Activation
2001
Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor
2000 StandoutScienceNobel
Vanilloid (Capsaicin) Receptors and Mechanisms
1999 Standout
The Asthma Epidemic
2006 Standout
A sulfated metabolite produced bystf3negatively regulates the virulence ofMycobacteriumtuberculosis
2006 StandoutNobel
Optimal assessment and management of chronic obstructive pulmonary disease (COPD). The European Respiratory Society Task Force
1995
Breathtaking TRP Channels: TRPA1 and TRPV1 in Airway Chemosensation and Reflex Control
2008
Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils
1997 StandoutNobel
Mast cell tryptase potentiates histamine-induced contraction in human sensitized bronchus
1997
Bronchial responsiveness and inflammation in guinea pigs exposed to acrolein
1989
The Effects of Plant Flavonoids on Mammalian Cells:Implications for Inflammation, Heart Disease, and Cancer
2000 Standout
Molecular Mechanisms RegulatinG Th1 Immune Responses
2003
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
Interleukin-13: Central Mediator of Allergic Asthma
1998 StandoutScience
Role of angiogenesis and vascular remodeling in chronic obstructive pulmonary disease.
2007
Mechanism of capsaicin-induced relaxation in equine tracheal smooth muscle
1997
Mechanisms of cigarette smoke-induced COPD: insights from animal models
2008
Long term outcome of soybean epidemic asthma after an allergen reduction intervention
1999
Longitudinal decline in lung function in patients with occupational asthma due to western red cedar.
1996
Bronchial biopsies and airway inflammation
1996
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
Works of Cristina E. Mapp being referenced
Airway wall remodeling after cessation of exposure to isocyanates in sensitized asthmatic subjects.
1995
Pharmacological modulation of the contractile response to toluene diisocyanate in the rat isolated urinary bladder
1990
Mast Cells in the Airway Mucosa and Rapid Development of Occupational Asthma Induced by Toluene Diisocyanate
1993
Dose-dependent inhibitory effect of inhaled beclomethasone on late asthmatic reactions and increased responsiveness to methacholine induced by toluene diisocyanate in sensitised subjects
1988
Effect of smoking cessation on airway inflammation in chronic bronchitis.
1995
Effects of Inhaled Beclomethasone on Airway Responsiveness in Occupational Asthma: Placebo-controlled Study of Subjects Sensitized to Toluene Diisocyanate
1993
Persistent Asthma Due to Isocyanates: A Follow-up Study of Subjects with Occupational Asthma Due to Toluene Diisocyanate (TDI)
1988
Cytokines in the airway mucosa of subjects with asthma induced by toluene diisocyanate.
1995
The C-C chemokine receptors CCR4 and CCR8 identify airway T cells of allergen-challenged atopic asthmatics
2001
Airflow limitation in chronic bronchitis is associated with T-lymphocyte and macrophage infiltration of the bronchial mucosa.
1996
Effect of Cessation of Exposure to Toluene Diisocyanate (TDI) on Bronchial Mucosa of Subjects with TDI-induced Asthma
1992
Fatal Asthma in a Subject Sensitized to Toluene Diisocyanate
1988
Protective Effect of Antiasthma Drugs on Late Asthmatic Reactions and Increased Airway Responsiveness Induced by Toluene Diisocyanate in Sensitized Subjects
1987
Airway Mucosal Inflammation in Occupational Asthma Induced by Toluene Diisocyanate
1992
The effects of toluene diisocyanate and of capsaicin on human bronchial smooth muscle in vitro
1994
Prostacyclin activates tachykinin release from capsaicin‐sensitive afferents in guinea‐pig bronchi through a ruthenium red‐sensitive pathway
1991
Airway Inflammation during Late Asthmatic Reactions Induced by Toluene Diisocyanate
1991
Sputum eosinophilia after asthmatic responses induced by isocyanates in sensitized subjects
1994
Comparison of leukocyte counts in sputum, bronchial biopsies, and bronchoalveolar lavage.
1995
Bronchial smooth muscle responses evoked by toluene diisocyanate are inhibited by ruthenium red and by indomethacin
1991
Glutathione S-transferase GSTP1 is a susceptibility gene for occupational asthma induced by isocyanates
2002
Bronchial hyperresponsiveness, airway inflammation and occupational asthma induced by toluene diisocyanate
1991
Evidence that toluene diisocyanate activates the efferent function of capsaicin-sensitive primary afferents
1990
Mechanisms of occupational asthma
2009
Venous blood platelets decrease during allergen‐induced asthmatic reactions
1990
CC ligand 2 levels are increased in LPS-stimulated peripheral monocytes of patients with non-small cell lung cancer
2007
Airway eosinophilia in chronic bronchitis during exacerbations.
1994
Bronchoalveolar Neutrophilia during Late Asthmatic Reactions Induced by Toluene Diisocyanate
1987
The Distribution of Neurokinin-1 and Neurokinin-2 Receptors in Human Central Airways
2000
Cellular and Structural Bases of Chronic Obstructive Pulmonary Disease
2001
Severity of Airflow Limitation Is Associated with Severity of Airway Inflammation in Smokers
1998
CD8 + ve Cells in the Lungs of Smokers with Chronic Obstructive Pulmonary Disease
1999
Occupational Asthma
2005
Goblet Cell Hyperplasia and Epithelial Inflammation in Peripheral Airways of Smokers with Both Symptoms of Chronic Bronchitis and Chronic Airflow Limitation
2000
NK 1 Receptor Stimulation Causes Contraction and Inositol Phosphate Increase in Medium-size Human Isolated Bronchi
2001
Increased VIP-Positive Nerve Fibers in the Mucous Glands of Subjects with Chronic Bronchitis
1997
Inflammatory Cells in the Bronchial Glands of Smokers with Chronic Bronchitis
1997
Increased Expression of Heme Oxygenase (HO)-1 in Alveolar Spaces and HO-2 in Alveolar Walls of Smokers
2001
Expression and Function of Proteinase-activated Receptor 2 in Human Bronchial Smooth Muscle
2001
American Thoracic Society Statement
2003 Standout
CD8 + T-Lymphocytes in Peripheral Airways of Smokers with Chronic Obstructive Pulmonary Disease
1998
Remodeling in Response to Infection and Injury
2001
Expression of interleukin (IL)‐4 and IL‐5 proteins in asthma induced by toluene diisocyanate (TDI)
1997
Prednisone inhibits late asthmatic reactions and the associated increase in airway responsiveness induced by toluene-diisocyanate in sensitized subjects.
1985
Prednisone inhibits late asthmatic reactions and airway inflammation induced by toluene diisocyanate in sensitized subjects
1987
Time course of the increase in airway responsiveness associated with late asthmatic reactions to toluene diisocyanate in sensitized subjects
1985