Standout Papers
Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
2013 StandoutScience
Sea Anemone Genome Reveals Ancestral Eumetazoan Gene Repertoire and Genomic Organization
2007 StandoutScience
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer
2017
Two Proteases Defining a Melanization Cascade in the Immune System of Drosophila
2006
Mitochondria and Epigenetics – Crosstalk in Homeostasis and Stress
2017
The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
2017 StandoutNobel
The N-terminal Domain of Drosophila Gram-negative Binding Protein 3 (GNBP3) Defines a Novel Family of Fungal Pattern Recognition Receptors
2009 StandoutNobel
Phylogenomics Revives Traditional Views on Deep Animal Relationships
2009 Standout
Ferroptosis: molecular mechanisms and health implications
2020 Standout
Early evolution of symmetry and polarity in metazoan body plans
2008
Altered metabolite levels in cancer: implications for tumour biology and cancer therapy
2016
Oncometabolites: linking altered metabolism with cancer
2013
Animal Evolution: Trichoplax, Trees, and Taxonomic Turmoil
2008
A Signaling Protease Required for Melanization in Drosophila Affects Resistance and Tolerance of Infections
2008
Sensing of 'danger signals' and pathogen-associated molecular patterns defines binary signaling pathways 'upstream' of Toll
2008
Insect hemolymph clotting
2009
Targeting Ferroptosis to Iron Out Cancer
2019 Standout
Hereditary Kidney Cancer Syndromes
2013
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
The <i>Drosophila</i> TNF Ortholog Eiger Is Required in the Fat Body for a Robust Immune Response
2010
Cancer-associated 2-oxoglutarate analogues modify histone methylation by inhibiting histone lysine demethylases
2018
Evolutionarily Conserved Roles of the Dicer Helicase Domain in Regulating RNA Interference Processing
2014 StandoutNobel
Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death
2019 Nature
Akirins are highly conserved nuclear proteins required for NF-κB-dependent gene expression in drosophila and mice
2007 StandoutNobel
Mitochondrial Metabolism as a Target for Cancer Therapy
2020
The gut microbiota of insects – diversity in structure and function
2013 Standout
Evolution of striated muscle: Jellyfish and the origin of triploblasty
2005
Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis
2015
Unsuspected task for an old team: Succinate, fumarate and other Krebs cycle acids in metabolic remodeling
2014
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
2015 StandoutNobel
The evolution of metazoan axial properties
2005
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Advances in the treatment of neurofibromatosis-associated tumours
2013
2-Oxoglutarate-dependent dioxygenases in cancer
2020 Nobel
A Model of Bacterial Intestinal Infections in Drosophila melanogaster
2007 StandoutNobel
Six major steps in animal evolution: are we derived sponge larvae?
2008
Oxidative Stress in Cancer
2020 Standout
Drosophila Immunity: A Large-Scale In Vivo RNAi Screen Identifies Five Serine Proteases Required for Toll Activation
2006
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
Lynch syndrome and urologic malignancies
2019
The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections
2007 StandoutNobel
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Multiple Dicer Genes in the Early-Diverging Metazoa
2009
Targeting ferroptosis as a vulnerability in cancer
2022 Standout
Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals
2008 StandoutNature
Genesis and Expansion of Metazoan Transcription Factor Gene Classes
2008
Broad phylogenomic sampling improves resolution of the animal tree of life
2008 StandoutNature
A Specific Primed Immune Response in Drosophila Is Dependent on Phagocytes
2007
Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases
2019 Standout
Metabolic dysregulation in monogenic disorders and cancer — finding method in madness
2015
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
2-Oxoglutarate-dependent dioxygenases are sensors of energy metabolism, oxygen availability, and iron homeostasis: potential role in the regulation of aging process
2015
Mitochondrial TCA cycle metabolites control physiology and disease
2020 Standout
Microbe sensing, positive feedback loops, and the pathogenesis of inflammatory diseases
2008 StandoutNobel
The proPO-system: pros and cons for its role in invertebrate immunity
2008
Renal cell carcinoma
2017 Standout
Cuticle laccase of the silkworm, Bombyx mori: Purification, gene identification and presence of its inactive precursor in the cuticle.
2009
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
NF- B in the Immune Response of Drosophila
2009 StandoutNobel
Thrombosis as an intravascular effector of innate immunity
2012 Standout
Research into cancer metabolomics: Towards a clinical metamorphosis
2015
Hypoxia-inducible factor induces cysteine dioxygenase and promotes cysteine homeostasis in Caenorhabditis elegans
2023 StandoutNobel
The Cambrian Conundrum: Early Divergence and Later Ecological Success in the Early History of Animals
2011 StandoutScience
Systematic Review: An Update on the Spectrum of Urological Malignancies in Lynch Syndrome
2018
Copper Active Sites in Biology
2014 Standout
Fundamentals of cancer metabolism
2016 Standout
Bladder Cancer
2020 Standout
Sponge-Associated Microorganisms: Evolution, Ecology, and Biotechnological Potential
2007 Standout
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
2019 StandoutNobel
A Renaissance of Elicitors: Perception of Microbe-Associated Molecular Patterns and Danger Signals by Pattern-Recognition Receptors
2009 Standout
Disease Tolerance as a Defense Strategy
2012 StandoutScience
TLRs and innate immunity
2008 StandoutNobel
Metabolic reprogramming and cancer progression
2020 StandoutScience
Clinical significance of T cell metabolic reprogramming in cancer
2016
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
The Host Defense of Drosophila melanogaster
2007 StandoutNobel
Combination therapy strategies for improving PD‐1 blockade efficacy: a new era in cancer immunotherapy
2017 StandoutNobel
Rare Germline Mutations Identified by Targeted Next-Generation Sequencing of Susceptibility Genes in Pheochromocytoma and Paraganglioma
2014
The New View of Animal Phylogeny
2004
Bacille Calmette-Guérin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes
2012 Standout
Works of Cosimo Martinelli being referenced
Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism
2015
Absence of microsatellite instability andBRAF(V600E) mutation in testicular germ cell tumors
2016
Distinct expression patterns of the two T-box homologues Brachyury and Tbx2/3 in the placozoan Trichoplax adhaerens
2003
Expression pattern of the homeobox gene Not in the basal metazoan Trichoplax adhaerens
2004
Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes
2011
T‐box and homeobox genes from the ctenophore Pleurobrachia pileus: Comparison of Brachyury, Tbx2/3 and Tlx in basal metazoans and bilaterians
2005
SDH Mutations Establish a Hypermethylator Phenotype in Paraganglioma
2013
Prophenoloxidase activation is not required for survival to microbial infections in Drosophila
2005 StandoutNobel