Citation Impact
Citing Papers
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro
2006 StandoutNobel
Suppression of Aging in Mice by the Hormone Klotho
2005 StandoutScience
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels
2006 StandoutNobel
Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice
2005 StandoutScience
Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age
2007
Beyond alcohol: Beverage consumption and cardiovascular mortality
1995
Abdominal obesity and metabolic syndrome
2006 StandoutNature
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Genetic effects on gene expression across human tissues
2017 StandoutNature
Sp1 Sites Mediate Activation of the Plasminogen Activator Inhibitor-1 Promoter by Glucose in Vascular Smooth Muscle Cells
1998
Structural basis for serpin inhibitor activity
1995
Mechanisms linking obesity with cardiovascular disease
2006 StandoutNature
Prospects for Cardiovascular Research
2001 StandoutNobel
Psychosocial stress and the insulin resistance syndrome
1996
Toward the quiescent coronary plaque
1993
Lowering Homocysteine in Patients With Ischemic Stroke to Prevent Recurrent Stroke, Myocardial Infarction, and Death
2004 Standout
Physical Exertion as a Trigger of Acute Myocardial Infarction
1993
Inactivation of the serpin α2-antiplasmin by stromelysin-1
2001
Inactivation of human plasma kallikrein and factor XIa by protein C inhibitor
1988
Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock
2002 Standout
Thrombin generation as an acute effect of cigarette smoking
1994
Insulin sensitivity and lipid metabolism with oral contraceptives containing chlormadinone acetate or desogestrel: a randomized trial
2008
The role of fat cell derived peptides in age-related metabolic alterations
2001
MTHFR 677C→T Polymorphism and Risk of Coronary Heart Disease
2002
Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline
2013 Standout
The Fibrinolytic System of the Vessel Wall and Its Role in the Control of Thrombosis
1990
Ca2+‐ and thromboxane‐dependent distribution of MaxiK channels in cultured astrocytes: From microtubules to the plasma membrane
2009
Rapid actions of plasma membrane estrogen receptors
2001
Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes
2017 Standout
Fibrinogen polymorphisms are not associated with the risk of myocardial infarction
2000
Obesity, haemostasis and the fibrinolytic system
2002
‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*
2003 Standout
The contribution of thrombosis to the clinical expression of coronary atherosclerosis
1996
Fibrinolytic response in normal subjects to venous occlusion and DDAVP infusion
1989
Glial and neuronal control of brain blood flow
2010 StandoutNature
Protective and Damaging Effects of Stress Mediators
1998 Standout
Even moderate cigarette smoking influences the pattern of circulating monocytes and the concentration of sICAM-1
1998
The long-term effects of metoprolol and epanolol on tissue-type plasminogen activator and plasminogen activator inhibitor 1 in patients with ischaemic heart disease
1994
The glycocalyx—linking albuminuria with renal and cardiovascular disease
2015
Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo. Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-alpha, and transforming growth factor-beta.
1991
Neonatal bleeding in transgenic mice expressing urokinase-type plasminogen activator
1990
Physiological consequences of loss of plasminogen activator gene function in mice
1994 Nature
Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization.
1993
Triggering and hourly variation of onset of arterial thrombosis
1992
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
2004 StandoutNature
The metabolic syndrome—a new worldwide definition
2005 Standout
Biochemistry and molecular cell biology of diabetic complications
2001 StandoutNature
Vitamin Intervention for Stroke Prevention (VISP) Trial: Rationale and Design
2001
Drosophila Clock Can Generate Ectopic Circadian Clocks
2003 StandoutNobel
C1 inhibitor hinge region mutations produce dysfunction by different mechanisms
1992
Fibrinolytic activity, clotting factors, and long-term incidence of ischaemic heart disease in the Northwick Park Heart Study
1993
Steroidal contraceptives: effect on carbohydrate metabolism in women without diabetes mellitus
2009
5, 10-Methylenetetrahydrofolate Reductase Gene Variants and Congenital Anomalies: A HuGE Review
2000
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
1996 StandoutNature
Inflammation, Atherosclerosis, and Coronary Artery Disease
2005 Standout
Stimulatory effect of unsaturated fatty acids on the level of plasminogen activator inhibitor‐1 mRNA in cultured human endothelial cells
1995 StandoutNobel
C-Reactive Protein and Other Markers of Inflammation in the Prediction of Cardiovascular Disease in Women
2000 Standout
Effects of captopril therapy on endogenous fibrinolysis in men with recent, uncomplicated myocardial infarction
1994
Coordination of circadian timing in mammals
2002 StandoutNature
The Epidemiology of Sepsis in the United States from 1979 through 2000
2003 Standout
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
Implantation and the placenta: key pieces of the development puzzle
1994 StandoutScience
Homocysteine and Atherothrombosis
1998 Standout
Endogenous thrombin potential is higher during the luteal phase than during the follicular phase of a normal menstrual cycle
2013 StandoutNobel
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells
1998 StandoutNature
Plasminogen activator inhibitors
1987
Development of the human coagulation system in the full-term infant
1987 Standout
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
2-Antiplasmin Gene Deficiency in Mice Is Associated With Enhanced Fibrinolytic Potential Without Overt Bleeding
1999
Serpin Structure, Mechanism, and Function
2002 Standout
Genetic Variation as a Guide to Drug Development
1998 Science
PAI-1 and the Metabolic Syndrome
2006
Diurnal variation of tissue-type plasminogen activator and its rapid inhibitor (PAI-1).
1989
Association of TNF2, a TNF-α Promoter Polymorphism, With Septic Shock Susceptibility and Mortality
1999 Standout
Relative Contribution of Insulin and Its Precursors to Fibrinogen and PAI-1 in a Large Population With Different States of Glucose Tolerance
1999
Association of Chronic Stress With Plasminogen Activator Inhibitor–1 in Healthy Middle-aged Men
1996
Plasminogen Activators, Tissue Degradation, and Cancer
1985 Standout
A moderate fish intake increases plasminogen activator inhibitor type-1 in human volunteers
1989
Interleukin-10 Deficiency Increases Atherosclerosis, Thrombosis, and Low-density Lipoproteins in Apolipoprotein E Knockout Mice
2003
A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis
1996 Standout
Circadian variation of acute myocardial infarction and the effect of low-dose aspirin in a randomized trial of physicians.
1990
Characterization of human endothelial cell urokinase-type plasminogen activator receptor protein and messenger RNA
1990
Guidelines for the Primary Prevention of Stroke
2014 Standout
Elevated C-Reactive Protein
2001
Sudden cardiac death. Support for a role of triggering in causation.
1993
Nongenomic Steroid Action: Controversies, Questions, and Answers
2003
Association of the Platelet Pl A Polymorphism of Glycoprotein IIb/IIIa and the Fibrinogen Bβ 448 Polymorphism With Myocardial Infarction and Extent of Coronary Artery Disease
1997
Total Synthesis of (+)-Madindoline A and (−)-Madindoline B, Potent, Selective Inhibitors of Interleukin 6. Determination of the Relative and Absolute Configurations
2000 StandoutNobel
Tissue-type plasminogen activator binding to human endothelial cells. Evidence for two distinct binding sites.
1988
A genetically clamped renin transgene for the induction of hypertension
2002 StandoutNobel
Interaction of single-chain urokinase-type plasminogen activator with human endothelial cells.
1990 StandoutNobel
The cancer connection
2002 StandoutNatureNobel
Circadian variation of tissue plasminogen activator and its inhibitor, von Willebrand factor antigen, and prostacyclin stimulating factor in men with ischaemic heart disease.
1993
Cancer Chemopreventive Activity of Resveratrol, a Natural Product Derived from Grapes
1997 StandoutScience
Coronary Plaque Disruption
1995 Standout
Stimulation of plasminogen activator inhibitor in vivo by infusion of angiotensin II. Evidence of a potential interaction between the renin-angiotensin system and fibrinolytic function.
1993
Association Between a Functional Variant of the KLOTHO Gene and High-Density Lipoprotein Cholesterol, Blood Pressure, Stroke, and Longevity
2005
Evidence for Antigen-Driven T-Cell Response in Unstable Angina
2000
IL-6 as a drug discovery target
1998
α 2 -Antiplasmin Enschede: Alanine Insertion and Abolition of Plasmin Inhibitory Activity
1987 Science
Endothelial cells in physiology and in the pathophysiology of vascular disorders.
1998 Standout
Nascent-Seq analysis of Drosophila cycling gene expression
2013 StandoutNobel
Fibrinogen as a key regulator of inflammation in disease
2011
Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics
1999 StandoutScience
The Metabolic Syndrome: Time for a Critical Appraisal
2005 Standout
A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling
2005 StandoutScience
Factors XI and XII and Prekallikrein in Sick and Healthy Premature Infants
1981
Evaluating Novel Cardiovascular Risk Factors: Can We Better Predict Heart Attacks?
1999
Extending Healthy Life Span—From Yeast to Humans
2010 StandoutScience
Insulin Resistance and Atherosclerosis
2006
C-Reactive Protein in Healthy Subjects: Associations With Obesity, Insulin Resistance, and Endothelial Dysfunction
1999 Standout
Steroidal contraceptives: effect on carbohydrate metabolism in women without diabetes mellitus
2014
Works of Cornelis Kluft being referenced
Determination of prekallikrein in human plasma: optimal conditions for activating prekallikrein.
1978
alpha 2-Antiplasmin Enschede: dysfunctional alpha 2-antiplasmin molecule associated with an autosomal recessive hemorrhagic disorder.
1987
Effect of low-dose heparin on urinary albumin excretion in insulin-dependent diabetes mellitus
1995
Short-term oestrogen replacement therapy improves insulin resistance, lipids and fibrinolysis in postmenopausal women with NIDDM
1997
Hyperhomocysteinaemia and endothelial dysfunction in young patients with peripheral arterial occlusive disease
1995
Effect of moderate dose of alcohol with evening meal on fibrinolytic factors
1994
Elevated fibrinogen and the relation to acute phase response in diabetic nephropathy
1996
Depression of factor XII-dependent fibrinolytic activity in survivors of acute myocardial infarction at risk of reinfarction
1993
A comparative study of the effects of gestodene 60 µg/ethinylestradiol 15 µg and desogestrel 150 µg/ethinylestradiol 20 µg on hemostatic balance, blood lipid levels and carbohydrate metabolism
1999
Beneficial effect of a moderately energy-restricted diet on fibrinolytic factors in non-obese men
1995
Circadian Variation of Fibrinolytic Activity in Blood
1991
Major circadian fluctuations in fibrinolytic factors and possible relevance to time of onset of myocardial infarction, sudden cardiac death and stroke
1988
Metabolic profile of a continuous versus a cyclic low-dose combined oral contraceptive after one year of use
2011
Polymorphisms in the Coagulation Factor VII Gene and the Risk of Myocardial Infarction
1998
Association of plasma fibrinogen levels with coronary artery disease, smoking and inflammatory markers
1996
The cardiovascular risk factor plasminogen activator inhibitor type 1 is related to insulin resistance
1993
Mortality risk in men is associated with a common mutation in the methylenetetrahydrofolate reductase gene (MTHFR)
1999
Fibrin Clot Formation and Lysis: Basic Mechanisms
2000
Studies on the Fibrinolytic System in Human Plasma: Quantitative Determination of Plasminogen Activators and Proactivators
1979
Identification of a reversible inhibitor of plasminogen activators in blood plasma
1985
Temporal Relation Between Ischemic Episodes and Activation of the Coagulation System in Unstable Angina
1996
−455G/A Polymorphism of the β-Fibrinogen Gene is Associated With the Progression of Coronary Atherosclerosis in Symptomatic Men
1998
Elevated Plasma Fibrinogen
1998
4G/4G Genotype of PAI-1 Gene Is Associated With Reduced Risk of Stroke in Elderly
2003
The postoperative fibrinolytic shutdown: a rapidly reverting acute phase pattern for the fast-acting inhibitor of tissue-type plasminogen activator after trauma
1985
A familial hemorrhagic diathesis in a Dutch family: an inherited deficiency of alpha 2-antiplasmin
1982
Gender-Related Association Between β-Fibrinogen Genotype and Plasma Fibrinogen Levels and Linkage Disequilibrium at the Fibrinogen Locus in Greenland Inuit
1995
On the Usefulness of Fibrinolysis Variables in the Characterization of a Risk Group for Myocardial Reinfarction
1987
Leiden fibrinolysis working party: blood collection and handling procedures for assessment of tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1)
1990
Depression of Tissue Plasminogen Activator (t-PA) Activity and Rise of t-PA Inhibition and Acute Phase Reactants in Blood of Patients with Acute Myocardial Infarction (AMI)
1987
Evidence for the Occurrence of a Fast-Acting Inhibitor for Tissue-Type Plasminogen Activator in Human Plasma
1984
Alpha 2-antiplasmin Enschede is not an inhibitor, but a substrate, of plasmin.
1988
Acute effect of smoking on fibrinolysis: increase in the activity level of circulating extrinsic (tissue‐type) plasminogen activator*
1984
Daytime Fluctuations in Blood of Tissue-Type Plasminogen Activator (t-PA) and Its Fast-Acting Inhibitor (PAI-1)
1988
Elevated Plasminogen Activator Inhibitor (PAI), a Cause of Thrombophilia? – A Study in 203 Patients with Familial or Sporadic Venous Thrombophilia
1989
Interaction study between nifedipine and recombinant tissue‐type plasminogen activator in healthy subjects.
1993
Acute exogenous hyperinsulinaemia does not result in elevation of plasma plasminogen activator inhibitor-1 (PAI-1) in humans
1990
Increased Thromboxane Biosynthesis Is Associated With Poststroke Dementia
1999
Effect of Oral Contraceptives on Haemostasis Variables
1997