Cornelia M. Smith

Planetary boundaries: Guiding human development on a changing planet

Endocrine Disruptors and Asthma-Associated Chemicals in Consumer Products

Probabilistic human health risk assessment of perfluorooctane sulfonate (PFOS) by integrating in vitro, in vivo toxicity, and human epidemiological studies using a Bayesian-based dose-response assessment coupled with physiologically based pharmacokinetic (PBPK) modeling approach

Occupational safety and health, green chemistry, and sustainability: a review of areas of convergence

Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA)

Characterization of lipid and lipoprotein metabolism in primary human hepatocytes

The effect of triclosan on the uterotrophic response to extended doses of ethinyl estradiol in the weanling rat

Activation of xenobiotic receptors: driving into the nucleus

Regulation of CYP3A4 and CYP2B6 expression by liver X receptor agonists

Guidance for the identification of endocrine disruptors in the context of Regulations (EU) No 528/2012 and (EC) No 1107/2009

Molecular Interactions between NAFLD and Xenobiotic Metabolism

Integrated Model of Chemical Perturbations of a Biological Pathway Using 18In VitroHigh-Throughput Screening Assays for the Estrogen Receptor

Organotypic liver culture models: Meeting current challenges in toxicity testing

Human Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming

Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

Relative Activation of Human Pregnane X Receptor versus Constitutive Androstane Receptor Defines Distinct Classes of CYP2B6 and CYP3A4 Inducers

Proposing a scientific confidence framework to help support the application of adverse outcome pathways for regulatory purposes

In Vitro and Modelling Approaches to Risk Assessment from the U.S. Environmental Protection Agency ToxCast Programme

EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals

Update on EPA’s ToxCast Program: Providing High Throughput Decision Support Tools for Chemical Risk Management

Consideration of dosimetry in evaluation of ToxCast™ data

Human serum leads to differentiation of human hepatoma cells, restoration of very-low-density lipoprotein secretion, and a 1000-fold increase in HCV Japanese fulminant hepatitis type 1 titers

Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research

The Tangle of Nuclear Receptors that Controls Xenobiotic Metabolism and Transport: Crosstalk and Consequences

Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses

Development and Validation of a Computational Model for Androgen Receptor Activity

Mechanisms of Renal Fibrosis

Pharmacogenetics of Anti-HIV Drugs

Differential Regulation of Hepatic CYP2B6 and CYP3A4 Genes by Constitutive Androstane Receptor but Not Pregnane X Receptor

Hepatocytes as a Tool in Drug Metabolism, Transport and Safety Evaluations in Drug Discovery

A comprehensive evaluation of metabolic activity and intrinsic clearance in suspensions and monolayer cultures of cryopreserved primary human hepatocytes

Incorporating Human Dosimetry and Exposure into High-ThroughputIn VitroToxicity Screening