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Citing Papers
Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O 2 activation
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The Stacking Tryptophan of Galactose Oxidase: A Second-Coordination Sphere Residue that Has Profound Effects on Tyrosyl Radical Behavior and Enzyme Catalysis ,
2007
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Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants
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Generation of protein-derived redoxcofactors by posttranslational modification
2010
Occurrence and Biocatalytic Potential of Carbohydrate Oxidases
2006
Crystal structure of a GA protein βγdimer at 2.1 Å resolution
1996 Nature
Reconstitution of Formylglycine-generating Enzyme with Copper(II) for Aldehyde Tag Conversion
2015
Function and Structure of a Prokaryotic Formylglycine-generating Enzyme
2008 StandoutNobel
Cu(I)-dependent Biogenesis of the Galactose Oxidase Redox Cofactor
2003
The development of mechanistic enzymology in the 20th century
2001
Structural Characterization of the Copper Site in Galactose Oxidase Using X-ray Absorption Spectroscopy
1994
Natural engineering principles of electron tunnelling in biological oxidation–reduction
1999 StandoutNature
The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription Factor
1997 StandoutNobel
Crystallographic investigations of the tryptophan‐derived cofactor in the quinoprotein methylamine dehydrogenase
1991
Buried Charged Surface in Proteins
2000
Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3
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Computational Enzyme Design
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2006
Enhanced Expression and Purification of Fungal Galactose Oxidase in Escherichia coli and Use for Analysis of a Saturation Mutagenesis Library
2011
Tyrosyl radicals in Photosystem II
2004
Crystal structure of a plant catechol oxidase containing a dicopper center
1998
Glyoxal Oxidase from Phanerochaete chrysosporium Is a New Radical-Copper Oxidase
1996
Hundreds of ankyrin‐like repeats in functionally diverse proteins: Mobile modules that cross phyla horizontally?
1993
Histidine-aromatic interactions in barnase
1992
The γ subunit in the Escherichia coli ATP synthase complex (ECF1F0) extends through the stalk and contacts the c subunits of the F0 part
1995
Probing the Function of the Tyr‐Cys Cross‐Link in Metalloenzymes by the Genetic Incorporation of 3‐Methylthiotyrosine
2012
THE ROLE OF REDOX‐ACTIVE AMINO ACIDS IN THE PHOTOSYNTHETIC WATER‐OXIDIZING COMPLEX
1993
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor
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Crystal structure of the β2 adrenergic receptor–Gs protein complex
2011 StandoutNatureNobel
The structure of the G protein heterotrimer Giα1β1γ2
1995 Nobel
Systematic development of computational models for the catalytic site in galactose oxidase: impact of outer-sphere residues on the geometric and electronic structures
2007
Biogenesis of Novel Quinone Coenzymes1
1995
[21] Tyrosyl radicals in photosystem II
1995
Thiol dioxygenases: unique families of cupin proteins
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Copper Protein Structures
1991
Biomimetic metal-radical reactivity: aerial oxidation of alcohols, amines, aminophenols and catechols catalyzed by transition metal complexes
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Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade
1997 Standout
How coenzyme B12 radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 å resolution
1996
Drosophila kelch motif is derived from a common enzyme fold
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Aerobic oxidation of primary alcohols catalyzed by copper complexes of 1,10-phenanthroline-derived ligands
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Anaerobic oxidation of methane coupled to nitrate reduction in a novel archaeal lineage
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The chemical biology of copper
1998
Enzymatic functionalization of carbon–hydrogen bonds
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Oxygen Binding, Activation, and Reduction to Water by Copper Proteins
2001
Enhanced Fructose Oxidase Activity in a Galactose Oxidase Variant
2004
A novel type of catalytic copper cluster in nitrous oxide reductase.
2000
Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor
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The radical chemistry of galactose oxidase
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Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs
2007 Standout
Crystal Structure of Agaricus bisporus Mushroom Tyrosinase: Identity of the Tetramer Subunits and Interaction with Tropolone
2011
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
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Integrins
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The α1.α2 Network of Collagen IV
2004
tea1 and the Microtubular Cytoskeleton Are Important for Generating Global Spatial Order within the Fission Yeast Cell
1997 StandoutNobel
Galactose Oxidase Model: Biomimetic Enantiomer‐Differentiating Oxidation of Alcohols by a Chiral Copper Complex
2008
Structure at 2.8 Å resolution of cytochrome c oxidase from Paracoccus denitrificans
1995 StandoutNatureNobel
Oxygen-18 kinetic isotope effects in the dopamine .beta.-monooxygenase reaction: Evidence for a new chemical mechanism in non-heme, metallomonooxygenase
1994
Copper amine oxidase: a novel use for a tyrosine
1995
Ligand interactions with galactose oxidase: mechanistic insights
1993
X-ray snapshots of quinone cofactor biogenesis in bacterial copper amine oxidase
2002
Novel cofactors via post-translational modifications of enzyme active sites
2000
Biologically inspired oxidation catalysis
2008 Nature
PROTEIN FOLDS IN THE ALL-β AND ALL-α CLASSES
1997
Copper K-extended x-ray absorption fine structure studies of oxidized and reduced dopamine beta-hydroxylase. Confirmation of a sulfur ligand to copper(I) in the reduced enzyme.
1991
Tyrosine codon corresponds to topa quinone at the active site of copper amine oxidases.
1992
Cu and Cu-Based Nanoparticles: Synthesis and Applications in Catalysis
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Mutations in Conserved Regions of the Predicted RAG2 Kelch Repeats Block Initiation of V(D)J Recombination and Result in Primary Immunodeficiencies
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Quantum Chemical Studies of Radical-Containing Enzymes
2003
Cross-Link Formation of the Cysteine 228−Tyrosine 272 Catalytic Cofactor of Galactose Oxidase Does Not Require Dioxygen
2008
A New Sulfur‐containing Schiff‐Base Ligand and Binding to Copper(II) and Cobalt(II)
2008
Crystal structure of the precursor of galactose oxidase: An unusual self-processing enzyme
2001
Multicopper Oxidases and Oxygenases
1996 Standout
Novel folded protein domains generated by combinatorial shuffling of polypeptide segments
2000 StandoutNobel
Copper Active Sites in Biology
2014 Standout
Aerobic Oxidation of Primary Alcohols (Including Methanol) by Copper(II)− and Zinc(II)−Phenoxyl Radical Catalysts
1999
A phenol–imidazole pro-ligand that can exist as a phenoxyl radical, alone and when complexed to copper(ii ) and zinc(ii )
2003
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
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Structural and Functional Aspects of Metal Sites in Biology
1996 Standout
Sequence and domain organization of scruin, an actin-cross-linking protein in the acrosomal process of Limulus sperm.
1995
The Role of Protein Crystallography in Defining the Mechanisms of Biogenesis and Catalysis in Copper Amine Oxidase
2012
Cloning, sequencing, expression, and regulation of the structural gene for the copper/topa quinone-containing methylamine oxidase from Arthrobacter strain P1, a gram-positive facultative methylotroph
1993
Synthetic Models of the Inactive Copper(II)−Tyrosinate and Active Copper(II)−Tyrosyl Radical Forms of Galactose and Glyoxal Oxidases
1997
Folding of the N-terminal, ligand-binding region of integrin α-subunits into a β-propeller domain
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C—H Bond Activation in Transition Metal Species from a Computational Perspective
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Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope
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The Cation−π Interaction
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Roles of mutation and recombination in the evolution of protein thermodynamics
2002 StandoutNobel
Cooperative Bond Scission in a Soft Porous Crystal Enables Discriminatory Gate Opening for Ethylene over Ethane
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An enantiopure galactose oxidase model: synthesis of chiral amino alcohols through oxidative kinetic resolution catalyzed by a chiral copper complex
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Spectro-electrochemical and DFT studies of a planar Cu(II)–phenolate complex active in the aerobic oxidation of primary alcohols
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Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
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Cation-π Interactions in Chemistry and Biology: A New View of Benzene, Phe, Tyr, and Trp
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THE ATP SYNTHASE—A SPLENDID MOLECULAR MACHINE
1997 StandoutNobel
In Situ Gap-Mode Raman Spectroscopy on Single-Crystal Au(100) Electrodes: Tuning the Torsion Angle of 4,4′-Biphenyldithiols by an Electrochemical Gate Field
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Ten Years of a Biomimetic Approach to the Copper(II) Radical Site of Galactose Oxidase
2007
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1998 StandoutNobel
Aerobic Copper-Catalyzed Organic Reactions
2013 Standout
Intramolecular electron transfer rate between active-site copper and topa quinone in pea seedling amine oxidase.
1993
Density functional methods applied to metalloenzymes
2003
Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization
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Quantum Chemical Studies of Radical-Containing Enzymes
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Iron-Sulfur Clusters: Nature's Modular, Multipurpose Structures
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Mechanisms Whereby Mononuclear Copper Proteins Functionalize Organic Substrates
1996 Standout
Aerial oxidation of primary alcohols and amines catalyzed by Cu(ii ) complexes of 2,2′-selenobis(4,6-di-tert-butylphenol) providing [O,Se,O]-donor atoms
2004
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Synthetic Models for Heme−Copper Oxidases
2004
Post-Translational His-Cys Cross-Linkage Formation in Tyrosinase Induced by Copper(II)−Peroxo Species
2011
Selective Light Supported Oxidation of Hexoses Using Air as Oxidant – Synthesis of Tetrahydroxyazepanes
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Catalytic Galactose Oxidase Models: Biomimetic Cu(II)-Phenoxyl-Radical Reactivity
1998 Science
Structure of the Oxidized Active Site of Galactose Oxidase from Realistic In Silico Models
2006
Catalytic Mechanism of Galactose Oxidase: A Theoretical Study
2000
A New Cofactor in a Prokaryotic Enzyme: Tryptophan Tryptophylquinone as the Redox Prosthetic Group in Methylamine Dehydrogenase
1991 Science
Protein Radicals in Enzyme Catalysis
1998 Standout
Mechanistic Studies on Synthetic Fe−S-Based Clusters and Their Relevance to the Action of Nitrogenases
2005 StandoutNobel
Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination
2010 StandoutNobel
Molecular Basis for Interactions of G Protein βγ Subunits with Effectors
1998 StandoutScienceNobel
Direct Electron Transfer to a Metalloenzyme Redox Center Coordinated to a Monolayer-Protected Cluster
2009
Point Mutations in the WD40 Domain of Eed Block Its Interaction with Ezh2
1998
Structural flexibility of the Gαs α-helical domain in the β 2 -adrenoceptor Gs complex
2011 StandoutNobel
Galactose Oxidase Pro-Sequence Cleavage and Cofactor Assembly Are Self-Processing Reactions
2000
Frozen Density Functional Free Energy Simulations of Redox Proteins: Computational Studies of the Reduction Potential of Plastocyanin and Rusticyanin
2003 StandoutNobel
Proton-Coupled Electron Transfer
2012 Standout
Works of Conrad Stevens being referenced
Novel thioether bond revealed by a 1.7 Å crystal structure of galactose oxidase
1991 Nature
Galactose oxidase: Molecular analysis and mutagenesis studies
1993
Three-dimensional structure of galactose oxidase: an enzyme with a built-in secondary cofactor
1992
Structure and mechanism of galactose oxidase: catalytic role of tyrosine 495
1997
Structure and mechanism of galactose oxidase. The free radical site.
1994
Preliminary studies of two active site mutants of galactose oxidase
1993
Galactose oxidase of Dactylium dendroides. Gene cloning and sequence analysis.
1992