Citation Impact
Citing Papers
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein
2002 StandoutScience
Distinct fibroblast lineages determine dermal architecture in skin development and repair
2013 StandoutNature
Role of the CLOCK Protein in the Mammalian Circadian Mechanism
1998 StandoutScience
Membrane Topology and Intracellular Processing of Cyclin M2 (CNNM2)
2012
Mutations in CNNM4 Cause Jalili Syndrome, Consisting of Autosomal-Recessive Cone-Rod Dystrophy and Amelogenesis Imperfecta
2009
Siglec-8 antibody reduces eosinophils and mast cells in a transgenic mouse model of eosinophilic gastroenteritis
2019
CNNM2 Mutations Cause Impaired Brain Development and Seizures in Patients with Hypomagnesemia
2014
The protein tyrosine phosphatase PRL-2 interacts with the magnesium transporter CNNM3 to promote oncogenesis
2014
Signal transduction via platelet-derived growth factor receptors
1998
ATR-Chk2 Signaling in p53 Activation and DNA Damage Response during Cisplatin-induced Apoptosis
2007
Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal
1993
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
2009 StandoutNature
Necroptosis and its role in inflammation
2015 StandoutNature
Cellular function and molecular structure of ecto-nucleotidases
2012
Insulin-Like Growth Factors I and II. Peptide, Messenger Ribonucleic Acid and Gene Structures, Serum, and Tissue Concentrations*
1989 Standout
Carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone (FCCP) as an O2− generator induces apoptosis via the depletion of intracellular GSH contents in Calu-6 cells
2008
Immunoglobulin-like Domain 4-mediated Receptor-Receptor Interactions Contribute to Platelet-derived Growth Factor-induced Receptor Dimerization
1997
Back to Central Tolerance
2004 Standout
Autoimmune Diseases
2001
Nucleotide signalling during inflammation
2014 StandoutNature
Role for ELOVL3 and Fatty Acid Chain Length in Development of Hair and Skin Function
2004 StandoutNobel
Platelet‐derived growth factor receptor alpha subunit deleted Patch mouse exhibits severe cardiovascular dysmorphogenesis
1995
Molecular basis of sequence-specific single-stranded DNA recognition by KH domains: solution structure of a complex between hnRNP K KH3 and single-stranded DNA
2002
The biology and management of non-small cell lung cancer
2018 StandoutNature
The genetic background of autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy and its autoimmune disease components
2002
Pathogenesis and therapy of psoriasis
2007 StandoutNature
Bone Dysplasia Sclerosteosis Results from Loss of the SOST Gene Product, a Novel Cystine Knot–Containing Protein
2001 StandoutNobel
Purinergic Signaling in the Airways
2012
BRAFE600-associated senescence-like cell cycle arrest of human naevi
2005 StandoutNature
Localization of a Novel Locus for Autosomal Recessive Early-Onset Parkinsonism, PARK6, on Human Chromosome 1p35-p36
2001
A decade of AIRE
2007
Cough and airway disease: The role of ion channels
2017
Wnt Signaling and an APC-Related Gene Specify Endoderm in Early C. elegans Embryos
1997 StandoutNobel
A Mutant Drosophila Homolog of Mammalian Clock Disrupts Circadian Rhythms and Transcription of period and timeless
1998 StandoutNobel
Expression of the insulin‐like and platelet‐derived growth factor genes in human uterine tissues
1990
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
1995 StandoutNature
Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways
2012
Wnt proteins are lipid-modified and can act as stem cell growth factors
2003 StandoutNature
Gout
2009 Standout
RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse
2000
Immunogenicity of induced pluripotent stem cells
2011 StandoutNature
Ligand-induced dimerization of growth factor receptors: Variations on the theme
1996
Molecular mechanisms of cisplatin resistance
2011 Standout
CNNM2, Encoding a Basolateral Protein Required for Renal Mg2+ Handling, Is Mutated in Dominant Hypomagnesemia
2011
Distribution and Functions of Platelet-Derived Growth Factors and Their Receptors during Embryogenesis
1997
Mutations in CNNM4 Cause Recessive Cone-Rod Dystrophy with Amelogenesis Imperfecta
2009
Aire deficient mice develop multiple features of APECED phenotype and show altered immune response
2002
Wnt/β-Catenin Signaling and Disease
2012 Standout
Mutations in the AIRE Gene: Effects on Subcellular Location and Transactivation Function of the Autoimmune Polyendocrinopathy-Candidiasis–Ectodermal Dystrophy Protein
2000
Cig30 and Pitx3 Genes Are Arranged in a Partially Overlapping Tail-to-Tail Array Resulting in Complementary Transcripts
1999
Cellular Distribution and Functions of P2 Receptor Subtypes in Different Systems
2004
Modulation of Aire regulates the expression of tissue-restricted antigens
2007
Initial sequence of the chimpanzee genome and comparison with the human genome
2005 StandoutNature
Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
2010 StandoutNature
Inhibition of apoptosis by Zn2+in renal tubular cells following ATP depletion
2004
Structural requirements for dimerization, glycosylation, secretion, and biological function of VPF/VEGF
1995
Protein modules and signalling networks
1995 StandoutNature
Malignant melanoma: modern black plague and genetic black box
1998
Ancient conserved domain protein‐1 binds copper and modifies its retention in cells
2007
Immunity by ubiquitylation: a reversible process of modification
2005
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
PDGF mediates cardiac microvascular communication.
1998
DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development
1999 Standout
Gentamicin-induced apoptosis in LLC-PK1 cells: Involvement of lysosomes and mitochondria
2005
Genetically Modified Human Epidermis Overexpressing PDGF-A Directs the Development of a Cellular and Vascular Connective Tissue Stroma When Transplanted to Athymic Mice–Implications for the Use of Genetically Modified Keratinocytes to Modulate Dermal Regeneration
1995
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
1996 StandoutNature
The Hallmarks of Aging
2013 Standout
Identification and characterization of a novel family of membrane magnesium transporters, MMgT1 and MMgT2
2007
Pericytes regulate the blood–brain barrier
2010 StandoutNature
Basolateral Mg2+ Extrusion via CNNM4 Mediates Transcellular Mg2+ Transport across Epithelia: A Mouse Model
2013
Recent advances into the understanding of mitochondrial fission
2012
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Localization of the ICF Syndrome to Chromosome 20 by Homozygosity Mapping
1998
RIPK3-Mediated Necroptosis Regulates Cardiac Allograft Rejection
2014
APECED mutations in the autoimmune regulator (AIRE) gene
2001
SLC41A1 Is a Novel Mammalian Mg2+ Carrier
2008
Developmental patterns of PDGF B-chain, PDGF-receptor, and α-actin expression in human glomerulogenesis
1992
Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein.
1993
Isolation of Putative Progenitor Endothelial Cells for Angiogenesis
1997 StandoutScience
Dominant-negative mutants of platelet-derived growth factor revert the transformed phenotype of human astrocytoma cells.
1993
Regulation and role of PDGF receptor a-subunit expression during embryogenesis
1992
Pathogenesis of Group A Streptococcal Infections
2000 Standout
Magnesium in Man: Implications for Health and Disease
2014 Standout
Aire
2009
Mutational analysis of mouse Wnt-1 identifies two temperature-sensitive alleles and attributes of Wnt-1 protein essential for transformation of a mammary cell line.
1992
A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit.
1991
PDGF-AB requires PDGF receptor alpha-subunits for high-affinity, but not for low-affinity, binding and signal transduction.
1993
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
2015 StandoutNobel
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
2008 StandoutNature
Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene
2001 StandoutNobel
Mitochondrial Fission, Fusion, and Stress
2012 StandoutScience
Platelet-derived growth factor alpha receptor gene expression: isolation and characterization of the promoter and upstream regulatory elements.
1994
W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity
1995 StandoutNature
Normal Thymic Architecture and Negative Selection Are Associated with Aire Expression, the Gene Defective in the Autoimmune-Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED)
2000
The PDGFα receptor is required for neural crest cell development and for normal patterning of the somites
1997
A PDGF receptor mutation in the mouse (Patch) perturbs the development of a non-neuronal subset of neural crest-derived cells
1992
Deletion of the c-kit protooncogene in the human developmental defect piebald trait.
1991
TRPM8 acute desensitization is mediated by calmodulin and requires PIP2: distinction from tachyphylaxis
2011
Evolutionary Divergence of Platelet-Derived Growth Factor Alpha Receptor Signaling Mechanisms
2003
Functional characterization of ACDP2 (ancient conserved domain protein), a divalent metal transporter
2005
AIRE Functions As an E3 Ubiquitin Ligase
2004
Subcellular Location and Expression Pattern of Autoimmune Regulator (Aire), the Mouse Orthologue for Human Gene Defective in Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)
2001
Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery
1997 Standout
Delineation of the Molecular Defects in the AIRE Gene in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Patients from Southern Italy
2002
The Mouse Clock Mutation Behaves as an Antimorph and Maps Within the W19H Deletion, Distal of Kit
1997
The effect of systemically administered PDGF-BB on the rodent skeleton
1996
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus
2018
T cell exclusion, immune privilege, and the tumor microenvironment
2015 StandoutScience
PDGF signalling is required for gastrulation of Xenopus laevis
1995
Cell-Type-Specific Expression of the Platelet-Derived Growth Factor α Receptor: a Role for GATA-Binding Protein
1996
Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.
1994 Standout
Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4
2013 StandoutNobel
Mutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldism.
1991
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism
2003 StandoutScience
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Developmental expression of the α receptor for platelet-derived growth factor, which is deleted in the embryonic lethal Patch mutation
1992
Platelet-derived growth factor-A and its receptor are expressed in separate, but adjacent cell layers of the mouse embryo
1992
Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor
1999 Standout
Testicular development involves the spatiotemporal control of PDGFs and PDGF receptors gene expression and action.
1995
Works of Cong‐Yi Wang being referenced
Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis
2010
Dietary and lifestyle changes associated with high prevalence of hyperuricemia and gout in the Shandong coastal cities of Eastern China.
2008
Molecular cloning and characterization of the mouse Acdp gene family
2004
Acidic pH inhibits ATP depletion-induced tubular cell apoptosis by blocking caspase-9 activation in apoptosome
2005
Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress
2005
Poststreptococcal reactive arthritis: Clinical characteristics and association with HLA-DR alleles
1998
The Autoimmune Regulator (AIRE) Is a DNA-binding Protein
2001
Characterization of mutations in patients with autoimmune polyglandular syndrome type 1 (APS1)
1998
Homozygosity and Linkage‐Disequilibrium Mapping of the Urofacial (Ochoa) Syndrome Gene to a 1‐cM Interval on Chromosome 10q23‐q24
1997
TNP-ATP-Resistant P2X Ionic Current on the Central Terminals and Somata of Rat Primary Sensory Neurons
2003
CCL2/CCR2-Dependent Recruitment of Th17 Cells but Not Tc17 Cells to the Lung in a Murine Asthma Model
2015
Caspase-mediated cleavage of ATM during cisplatin-induced tubular cell apoptosis: inactivation of its kinase activity toward p53
2006
Cloning ofAire,the Mouse Homologue of the Autoimmune Regulator (AIRE) Gene Responsible for Autoimmune Polyglandular Syndrome Type 1 (APS1)
1999
Gene delivery of indoleamine 2,3‐dioxygenase prolongs cardiac allograft survival by shaping the types of T‐cell responses
2008
Expression and Alternative Splicing of the Mouse Autoimmune Regulator Gene ( )
1999
Molecular cloning and characterization of a novel gene family of four ancient conserved domain proteins (ACDP)
2003
Construction of a Physical and Transcript Map for a 1-Mb Genomic Region Containing the Urofacial (Ochoa) Syndrome Gene on 10q23–q24 and Localization of the Disease Gene within Two Overlapping BAC Clones (<360 kb)
1999
High resolution mapping and mutation analyses of candidate genes in the urofacial syndrome (UFS) critical region
2003
Minocycline Up-regulates Bcl-2 and Protects against Cell Death in Mitochondria
2004
Effects of hydroxyl radical scavenging on cisplatin-induced p53 activation, tubular cell apoptosis and nephrotoxicity
2007
Extracellular Hmgb1 Functions as an Innate Immune-Mediator Implicated in Murine Cardiac Allograft Acute Rejection
2007
Molecular Cloning and Characterization of a Novel Mammalian Endo-apyrase (LALP1)
2001
TRPM8 Mechanism of Autonomic Nerve Response to Cold in Respiratory Airway
2008
Dominant-negative mutants of a platelet-derived growth factor gene.
1990
Isolation of an insulin-like growth factor II cDNA with a unique 5' untranslated region from human placenta.
1988
Platelet-derived growth factor receptor alpha-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation.
1991
Expression of insulin-like growth factor II in human placentas from normal and diabetic pregnancies.
1986
Physical Interaction and Functional Coupling between ACDP4 and the Intracellular Ion Chaperone COX11, an Implication of the Role of ACDP4 in Essential Metal Ion Transport and Homeostasis
2005