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Citing Papers
Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production
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Rosiglitazone (BRL49653), a PPARγ-selective agonist, causes peroxisome proliferator-like liver effects in obese mice
1999
Two-generation reproduction and cross-foster studies of perfluorooctanesulfonate (PFOS) in rats
2005
Molecular mediators of hepatic steatosis and liver injury
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Isomer Profiling of Perfluorinated Substances as a Tool for Source Tracking: A Review of Early Findings and Future Applications
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Negative bias from analog methods used in the analysis of free thyroxine in rat serum containing perfluorooctanesulfonate (PFOS)
2007
Peroxisome proliferator-activated receptors in vascular biology and atherosclerosis: Emerging insights for evolving paradigms
2000
Thiazolidinediones
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Mitochondrial Permeability Transition as the Critical Target of N-Acetyl Perfluorooctane Sulfonamide Toxicity in Vitro
2004
Reactions in Droplets in Microfluidic Channels
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Effects of perfluorooctane sulfonate on mallard and northern bobwhite quail exposed chronically via the diet
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A comparison of the pharmacokinetics of perfluorobutanesulfonate (PFBS) in rats, monkeys, and humans
2008
Inhibition of Gap Junctional Intercellular Communication by Perfluorinated Compounds in Rat Liver and Dolphin Kidney Epithelial Cell Lines in Vitro and Sprague-Dawley Rats in Vivo
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PPARα Agonist-Induced Rodent Tumors: Modes of Action and Human Relevance
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Vascularized and functional human liver from an iPSC-derived organ bud transplant
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Effects of prenatal perfluorooctane sulfonate (PFOS) exposure on lung maturation in the perinatal rat
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Biomonitoring of perfluorochemicals and toxicity to the downstream fish community of Etobicoke Creek following deployment of aqueous film-forming foam
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Epidemiologic Assessment of Worker Serum Perfluorooctanesulfonate (PFOS) and Perfluorooctanoate (PFOA) Concentrations and Medical Surveillance Examinations
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Perfluoroalkyl Acids: A Review of Monitoring and Toxicological Findings
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Subacute exposure to N-ethyl perfluorooctanesulfonamidoethanol results in the formation of perfluorooctanesulfonate and alters superoxide dismutase activity in female rats
2009
Nonalcoholic Fatty Liver Disease
2002 Standout
Congener-specific numbering systems for the environmentally relevant C4through C8perfluorinated homologue groups of alkyl sulfonates, carboxylates, telomer alcohols, olefins, and acids, and their derivatives
2008
Exposure to Perfluorooctane Sulfonate during Pregnancy in Rat and Mouse. II: Postnatal Evaluation
2003
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
Mechanism of Action of the Nongenotoxic Peroxisome Proliferators: Role of the Peroxisome Proliferator-Activated Receptor
1998
Steatohepatitis, Spontaneous Peroxisome Proliferation and Liver Tumors in Mice Lacking Peroxisomal Fatty Acyl-CoA Oxidase
1998
Global emission inventories for C4–C14 perfluoroalkyl carboxylic acid (PFCA) homologues from 1951 to 2030, Part I: production and emissions from quantifiable sources
2014
The peroxisome proliferator (PP) response element upstream of the human acyl CoA oxidase gene is inactive among a sample human population: significance for species differences in response to PPs
1999
Comparison of gene expression methods to identify genes responsive to perfluorooctane sulfonic acid
2004
Analysis of Episodes of Care in a Perfluorooctanesulfonyl Fluoride Production Facility
2004
Hepatic differentiation of human pluripotent stem cells in miniaturized format suitable for high-throughput screen
2016
Potent suppression of the adaptive immune response in mice upon dietary exposure to the potent peroxisome proliferator, perfluorooctanoic acid
2002
Hydrogen peroxide metabolism during peroxisome proliferation by fenofibrate
1995
Characterization of risk for general population exposure to perfluorooctanoate
2004
PPAR: a mediator of peroxisome proliferator action
1995
Mortality of employees of a perfluorooctanesulphonyl fluoride manufacturing facility
2003
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
1990 StandoutNature
Further evidence for the involvement of inhibition of cell proliferation and development in thymic and splenic atrophy induced by the peroxisome proliferator perfluoroctanoic acid in mice33Abbreviations: PFOA, perfluorooctanoic acid; PP, peroxisome proliferator; FBS, fetal bovine serum; FITC, fluorescein isothiocyanate; and DEHP, di(2-ethylhexyl)phthalate.
2001
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Peroxisome Proliferator‐activated Receptors: Stuctures and Function
1996
A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations
2008 StandoutNobel
Identification of genes responsive to PFOS using gene expression profiling
2004
Peroxisome proliferator-activated receptor alpha: role in rodent liver cancer and species differences
1999
Cytokines in non-genotoxic hepatocarcinogenesis
1999
PLASMA CHOLECYSTOKININ AND HEPATIC ENZYMES, CHOLESTEROL AND LIPOPROTEINS IN AMMONIUM PERFLUOROOCTANOATE PRODUCTION WORKERS
2000
Dose-Dependent Alterations in Androgen-Regulated Male Reproductive Development in Rats Exposed to Di(n-butyl) Phthalate during Late Gestation
2000 Standout
Epigenetic Modulation of miR-122 Facilitates Human Embryonic Stem Cell Self-Renewal and Hepatocellular Carcinoma Proliferation
2011
Evidence for the suppression of apoptosis by the peroxisome proliferator activated receptor alpha (PPAR alpha)
1998
The developmental toxicity of perfluoroalkyl acids and their derivatives
2004
Diabetes and Atherosclerosis
2002 Standout
Peroxisome Proliferator-Activated Receptor Agonists Inhibit Inflammatory Edema and Hyperalgesia
2002
Sofosbuvir Inhibits Hepatitis E Virus Replication In Vitro and Results in an Additive Effect When Combined With Ribavirin
2015 StandoutNobel
trans-Activation of PPAR and Induction of PPAR Target Genes by Perfluorooctane-Based Chemicals
2004
A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia
2017
Central administration of perfluorooctanoic acid inhibits cutaneous inflammation
2005
Subchronic Toxicity Studies on Perfluorooctanesulfonate Potassium Salt in Cynomolgus Monkeys
2002
Evidence for Transcriptional Induction of the Liver Fatty-Acid-Binding-Protein Gene by Bezafibrate in the Small Intestine
1995
Species differences in sequence and activity of the peroxisome proliferator response element (PPRE) within the acyl CoA oxidase gene promoter
1999
Exposure to Perfluorooctane Sulfonate during Pregnancy in Rat and Mouse. I: Maternal and Prenatal Evaluations
2003
Bladder Cancer in Perfluorooctanesulfonyl Fluoride Manufacturing Workers
2007
Inflammation and cancer: back to Virchow?
2001 Standout
PPARγ signaling and metabolism: the good, the bad and the future
2013 Standout
Spin Trapping: ESR parameters of spin adducts 1474 1528V
1987 Standout
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Neonatal mortality from in utero exposure to perfluorooctanesulfonate (PFOS) in Sprague–Dawley rats: Dose–response, and biochemical and pharamacokinetic parameters
2005
Differential induction and regulation of peroxisomal enzymes: Predictive value of peroxisome proliferation in identifying certain nonmutagenic carcinogens
1989
Mechanisms of fatty acid-induced inhibition of glucose uptake.
1994 Standout
Serum concentrations of perfluorooctanesulfonate and other fluorochemicals in an elderly population from Seattle, Washington
2003
The hormone resistin links obesity to diabetes
2001 StandoutNature
Opposite regulation of human versus mouse apolipoprotein A-I by fibrates in human apolipoprotein A-I transgenic mice.
1996
Toxicity of Ammonium Perfluorooctanoate in Male Cynomolgus Monkeys after Oral Dosing for 6 Months
2002
Some issues relating to the use of perfluorooctanesulfonate (PFOS) samples as reference standards
2007
Perfluorinated chemicals in selected residents of the American continent
2005
Synthesis of environmentally relevant fluorinated surfactants—a review
2005
Evaluation of biochemical effects related to perfluorooctane sulfonic acid exposure in organohalogen-contaminated great tit (Parus major) and blue tit (Parus caeruleus) nestlings
2005
Hepatoblast-Like Progenitor Cells Derived From Embryonic Stem Cells Can Repopulate Livers of Mice
2010
'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
1999 Standout
Oxidative DNA damage caused by persistent peroxisome proliferation: its role in hepatocarcinogenesis
1989
Application of comparative functional genomics to identify best-fit mouse models to study human cancer
2004
Perfluorooctane sulfonic acid and organohalogen pollutants in liver of three freshwater fish species in Flanders (Belgium): relationships with biochemical and organismal effects
2005
Cytochrome P450 ω-Hydroxylase Pathway of Tocopherol Catabolism
2002 Standout
Peroxisomes and oxidative stress
2006
Potential urinary and plasma biomarkers of peroxisome proliferation in the rat: identification ofN-methylnicotinamide andN-methyl-4-pyridone-3-carboxamide by1H nuclear magnetic resonance and high performance liquid chromatography
2003
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens
2015 StandoutNobel
Interactions of flurochemicals with rat liver fatty acid-binding protein
2002
Peroxisome Proliferator-Activated Receptor-alpha and the Pleiotropic Responses to Peroxisome Proliferators
1998
Self-Reported Medical Conditions in Perfluorooctanesulfonyl Fluoride Manufacturing Workers
2007
Prenatal window of susceptibility to perfluorooctane sulfonate‐induced neonatal mortality in the Sprague‐Dawley rat
2003
trans-Activation of PPARα and PPARγ by Structurally Diverse Environmental Chemicals
1999
Inhibition and induction of human cytochrome P450 (CYP) enzymes
1998
PFOS or PreFOS? Are perfluorooctane sulfonate precursors (PreFOS) important determinants of human and environmental perfluorooctane sulfonate (PFOS) exposure?
2010
Induction of Cyclooxygenase-2 Expression by Peroxisome Proliferators and Non-tetradecanoylphorbol 12,13-Myristate-type Tumor Promoters in Immortalized Mouse Liver Cells
1997
Alterations in cell membrane properties caused by perfluorinated compounds
2003
Stem cell-derived polarized hepatocytes
2020 StandoutNobel
Roles of PPARs in health and disease
2000 StandoutNature
Adipose Tissue as an Endocrine Organ
2004 Standout
Effect of potassium perfluorooctanesulfonate, perfluorooctanoate and octanesulfonate on the phase transition of dipalmitoylphosphatidylcholine (DPPC) bilayers
2007
Determination of ten perfluorinated compounds in bluegill sunfish (Lepomis macrochirus) fillets
2009
Highly Efficient Generation of Human Hepatocyte–Like Cells From Induced Pluripotent Stem Cells
2009
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
The Toxicology of Perfluorooctanoate
2004
Oxidants, antioxidants, and the degenerative diseases of aging.
1993 Standout
Identification of Farnesoid X Receptor β as a Novel Mammalian Nuclear Receptor Sensing Lanosterol
2003 StandoutNobel
Cyclooxygenases: Structural, Cellular, and Molecular Biology
2000 Standout
The Free Radical Theory of Aging Matures
1998 Standout
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
Myocardial Fatty Acid Metabolism in Health and Disease
2010 Standout
Characterization of the adipose tissue atrophy induced by peroxisome proliferators in mice
2002
Perfluorooctanesulfonate and Related Fluorochemicals in Human Blood Samples from China
2005
The Mechanisms of Action of PPARs
2002 Standout
Detection of Perfluorooctane Surfactants in Great Lakes Water
2004
Perfluorooctane Sulfonate (PFOS) and Related Perfluorinated Compounds in Human Maternal and Cord Blood Samples: Assessment of PFOS Exposure in a Susceptible Population during Pregnancy
2004
Historical Comparison of Perfluorooctanesulfonate, Perfluorooctanoate, and Other Fluorochemicals in Human Blood
2005
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Partial life-cycle toxicity and bioconcentration modeling of perfluorooctanesulfonate in the northern leopard frog (Rana pipiens)
2004
Cord Serum Concentrations of Perfluorooctane Sulfonate (PFOS) and Perfluorooctanoate (PFOA) in Relation to Weight and Size at Birth
2007
Modeling hepatitis C virus infection using human induced pluripotent stem cells
2012 StandoutNobel
Effects of peroxisome proliferators on the thymus and spleen of mice
2000
Polyfluorinated Compounds: Past, Present, and Future
2011 Standout
Automated Solid-Phase Extraction and Measurement of Perfluorinated Organic Acids and Amides in Human Serum and Milk
2004
Formation of 8-hydroxydeoxyguanosine in liver DNA of rats following long-term exposure to a peroxisome proliferator.
1989
PFAS Environmental Pollution and Antioxidant Responses: An Overview of the Impact on Human Field
2020
Perfluoroalkyl and polyfluoroalkyl substances in the environment: Terminology, classification, and origins
2011 Standout
Selective modification of rat hepatic microsomal fatty acid chain elongation and desaturation by fibrates: relationship with peroxisome proliferation
1995
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells
2012 StandoutNobel
Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases
2014 Standout
Perfluorochemicals in Pooled Serum Samples from United States Residents in 2001 and 2002
2006
Highly Efficient Differentiation of Functional Hepatocytes From Human Induced Pluripotent Stem Cells
2013
Evidence for Transcriptional Induction of the Liver Fatty‐Acid‐Binding‐Protein Gene by Bezafibrate in the Small Intestine
1995
Environmental Implications of Hydroxyl Radicals (•OH)
2015 Standout
The PPARs: From Orphan Receptors to Drug Discovery
2000 Standout
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ
1997 Standout
Peroxisome proliterators and cancer: mechanisms and implications
1986
The Applicability of Biomonitoring Data for Perfluorooctanesulfonate to the Environmental Public Health Continuum
2006
Association between Serum Perfluorooctanoic Acid (PFOA) and Thyroid Disease in the U.S. National Health and Nutrition Examination Survey
2010
Replicons of a Rodent Hepatitis C Model Virus Permit Selection of Highly Permissive Cells
2019 StandoutNobel
Perfluorooctanesulfonate and other fluorochemicals in the serum of American Red Cross adult blood donors.
2003
Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*
1999 Standout
Per- and polyfluoroalkyl substances in the environment
2022 StandoutScience
Molecular mediators of hepatic steatosis and liver injury
2004 Standout
Decreased susceptibility to copper‐induced oxidation of rat‐lipoproteins after fibrate treatment: influence of fatty acid composition
1996
Generation and Detection of Reactive Oxygen Species in Photocatalysis
2017 Standout
Health Risks in Infants Associated with Exposure to Perfluorinated Compounds in Human Breast Milk from Zhoushan, China
2006
Human Donor Liver and Serum Concentrations of Perfluorooctanesulfonate and Other Perfluorochemicals
2003
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators.
2000
Works of Cliff Elcombe being referenced
Immediate-Early Gene Expression during Regenerative and Mitogen-Induced Liver Growth in the Rat
1998
On the mechanism of induction of microsomal cytochrome P450IVA1 and peroxisome proliferation in rat liver by clofibrate
1990
Hepatic peroxisome proliferation in rodents and its significance for humans
1993
A Cancer Risk Assessment of Di(2-ethylhexyl)phthalate: Application of the New U.S. EPA Risk Assessment Guidelines
1999
Sub-chronic dietary toxicity of potassium perfluorooctanesulfonate in rats
2003
Hepatotoxin-induced hypertaurinuria: a proton NMR study
1990
Immediate‐Early Gene Expression during Regenerative and Mitogen‐Induced Liver Growth in the Rat
1998
Mechanistically-based Human Hazard Assessment of Peroxisome Proliferator-induced Hepatocarcinogenesis
1994
Efficient Differentiation of Hepatocytes from Human Embryonic Stem Cells Exhibiting Markers Recapitulating Liver Development In Vivo
2008
Do Peroxisome Proliferating Compounds Pose a Hepatocarcinogenic Hazard to Humans?
1998
Increased hydroxyl radical production in liver peroxisomal fractions from rats treated with peroxisome proliferators
1986