Citation Impact
Citing Papers
Differential Antigen Processing by Dendritic Cell Subsets in Vivo
2007 StandoutScienceNobel
Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8
2004 StandoutScience
Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice
2005
Systemic CTLA-4 Blockade Ameliorates Glioma-Induced Changes to the CD4+ T Cell Compartment without Affecting Regulatory T-Cell Function
2007 StandoutNobel
High-Content Screening Assay for Activators of the Wnt/Fzd Pathway in Primary Human Cells
2005
Single immunizations of self-amplifying or non-replicating mRNA-LNP vaccines control HPV-associated tumors in mice
2023 StandoutNobel
Untangling the ErbB signalling network
2001 Standout
Hallmarks of Cancer: The Next Generation
2011 Standout
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
MFG-E8–mediated uptake of apoptotic cells by APCs links the pro- and antiinflammatory activities of GM-CSF
2007
ErbB-targeted therapeutic approaches in human cancer
2003
A family with osteoporosis pseudoglioma syndrome due to compound heterozygosity of two novel mutations in the LRP5 gene
2006
Cysteine cathepsin proteases as pharmacological targets in cancer
2007
Analysis of multiple bone responses to graded strains above functional levels, and to disuse, in mice in vivo show that the human Lrp5 G171V High Bone Mass mutation increases the osteogenic response to loading but that lack of Lrp5 activity reduces it
2011
Wnt signaling in the stem cell niche
2004
Wnt signaling control of bone cell apoptosis
2008
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21
2006 StandoutNature
DCC and netrins
1998
Role of wnts in prostate cancer bone metastases
2005
The microbiota in adaptive immune homeostasis and disease
2016 StandoutNature
Genetic regulation of bone mass and susceptibility to osteoporosis
2006
Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus
2003 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Lipid nanoparticles for mRNA delivery
2021 Standout
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance
2008 Nature
Targeting the Wnt/β-Catenin Pathway to Regulate Bone Formation in the Adult Skeleton
2007
Tumor Suppressing Pathways
1998
Wnt Proteins Prevent Apoptosis of Both Uncommitted Osteoblast Progenitors and Differentiated Osteoblasts by β-Catenin-dependent and -independent Signaling Cascades Involving Src/ERK and Phosphatidylinositol 3-Kinase/AKT
2005
Extracellular control of TGFβ signalling in vascular development and disease
2007
The type III epidermal growth factor receptor mutation
2001
Kinase-mediated transcription, activators of nongenotropic estrogen–like signaling (ANGELS), and osteoporosis: A different perspective on the HRT dilemma
2004
Pattern Recognition Receptors and Inflammation
2010 Standout
Osteocytes, mechanosensing and Wnt signaling
2008
The cell biology of antigen presentation in dendritic cells
2001
Control of Bone Mass and Remodeling by PTH Receptor Signaling in Osteocytes
2008
Wnt Signaling Stimulates Osteoblastogenesis of Mesenchymal Precursors by Suppressing CCAAT/Enhancer-binding Protein α and Peroxisome Proliferator-activated Receptor γ
2007
Sclerostin Binds to LRP5/6 and Antagonizes Canonical Wnt Signaling
2005
Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells
2003 Nature
Lysosomal cysteine proteases: more than scavengers
2000
Autophagy: Renovation of Cells and Tissues
2011 Standout
Immunogenicity of induced pluripotent stem cells
2011 StandoutNature
Wnt inhibitory factor (WIF)-1 inhibits osteoblastic differentiation in mouse embryonic mesenchymal cells
2009
Large-Scale Analysis of Association Between <emph type="ital">LRP5</emph> and <emph type="ital">LRP6</emph> Variants and Osteoporosis
2008
WNT signaling in bone homeostasis and disease: from human mutations to treatments
2013 Standout
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
Mouse models for colorectal cancer
1999
The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor
2008 Nature
Targeted Molecular Therapy of GBM
2003
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Immunity, Inflammation, and Cancer
2010 Standout
Oxidative Stress Antagonizes Wnt Signaling in Osteoblast Precursors by Diverting β-Catenin from T Cell Factor- to Forkhead Box O-mediated Transcription
2007
The Wnt Co-receptor LRP5 Is Essential for Skeletal Mechanotransduction but Not for the Anabolic Bone Response to Parathyroid Hormone Treatment
2006
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Crystal structure of cathepsin X: a flip–flop of the ring of His23 allows carboxy-monopeptidase and carboxy-dipeptidase activity of the protease
2000
Suppression of Wnt Signaling by Dkk1 Attenuates PTH-Mediated Stromal Cell Response and New Bone Formation
2010
Cell adhesion and signalling by cadherins and Ig-CAMs in cancer
2004
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Clinical and Molecular Findings in Osteoporosis-Pseudoglioma Syndrome
2005
Bone anabolic effects of parathyroid hormone are blunted by deletion of the Wnt antagonist secreted frizzled‐related protein‐1
2006
LRP5 Mutations Linked to High Bone Mass Diseases Cause Reduced LRP5 Binding and Inhibition by SOST
2006
BMPs as Mediators of Roof Plate Repulsion of Commissural Neurons
1999
multifunctional enzymes in cancer
2006
Wnt/β-Catenin Signaling Is a Normal Physiological Response to Mechanical Loading in Bone
2006
A Wnt canon orchestrating osteoblastogenesis
2006
Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation
2005
Regulation of bone mass by Wnt signaling
2006
Wnt/β-Catenin Signaling in Development and Disease
2006 Standout
IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion
2010
Wnt-independent activation of β-catenin mediated by a Dkk1-Fz5 fusion protein
2005
A role for axon guidance receptors and ligands in blood vessel development and tumor angiogenesis
2005
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Class II MHC peptide loading by the professionals
2003
Modulation of Wnt signaling influences fracture repair
2010
Role of Transforming Growth Factor-beta Signaling in Cancer
2000
PHENIX: a comprehensive Python-based system for macromolecular structure solution
2010 Standout
Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia
2006
Multiple Transforming Growth Factor-β Isoforms and Receptors Function during Epithelial-Mesenchymal Cell Transformation in the Embryonic Heart
2007
Inflammation, Atherosclerosis, and Coronary Artery Disease
2005 Standout
Genetics of osteoporosis: accelerating pace in gene identification and validation
2009
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S
2014
Genes that mediate breast cancer metastasis to lung
2005 StandoutNature
Wnt signalling in stem cells and cancer
2005 StandoutNature
Molecular Bases of the Regulation of Bone Remodeling by the Canonical Wnt Signaling Pathway
2006
Neurotrophins and Netrins Require Calcineurin/NFAT Signaling to Stimulate Outgrowth of Embryonic Axons
2003
F-Spondin Is Required for Accurate Pathfinding of Commissural Axons at the Floor Plate
1999
Negative Regulation of Bone Formation by the Transmembrane Wnt Antagonist Kremen-2
2010
Angiogenesis as a therapeutic target
2005 StandoutNature
Autophagy in immunity and inflammation
2011 StandoutNature
Essential Role of β-Catenin in Postnatal Bone Acquisition
2005
Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib
2004 Standout
Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults
2003 Standout
LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling
2013 StandoutNature
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity
2022 StandoutNobel
Misguided Axonal Projections, Neural Cell Adhesion Molecule 180 mRNA Upregulation, and Altered Behavior in Mice Deficient for the Close Homolog of L1
2002
The Th17 Pathway and Inflammatory Diseases of the Intestines, Lungs, and Skin
2011
The role of Dickkopf-1 in bone development, homeostasis, and disease
2008
Axonal Ephrin-As and Odorant Receptors
2003 StandoutNobel
Deficiencies of GM-CSF and Interferon γ Link Inflammation and Cancer
2003
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8 + T cells in a spectrum of human MHC I haplotypes
2007 StandoutNobel
In Vivo Analysis of Wnt Signaling in Bone
2007
GROWTH CONE GUIDANCE: First Steps Towards a Deeper Understanding
1999
Gene Regulatory Networks and the Evolution of Animal Body Plans
2006 StandoutScience
Wnt10b Increases Postnatal Bone Formation by Enhancing Osteoblast Differentiation
2007
Osteocyte Wnt/β-Catenin Signaling Is Required for Normal Bone Homeostasis
2010
Lrp6 Hypomorphic Mutation Affects Bone Mass Through Bone Resorption in Mice and Impairs Interaction With Mesd
2008 StandoutNobel
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
Two distinctive pathways for recruitment of naïve and primed IgM+B cells to the gut lamina propria
2005 StandoutNobel
A protease-resistant immunotoxin against CD22 with greatly increased activity against CLL and diminished animal toxicity
2008
N-Cadherin Interacts with Axin and LRP5 To Negatively Regulate Wnt/β-Catenin Signaling, Osteoblast Function, and Bone Formation
2008
Regulation of osteoblastogenesis and bone mass by Wnt10b
2005
Overexpression of secreted frizzled-related protein 1 inhibits bone formation and attenuates parathyroid hormone bone anabolic effects
2009
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage
2004 StandoutNobel
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling:Arrows point the way
2004
Neural Science
2000 StandoutNobel
Lysosomal Cysteine Proteases in Atherosclerosis
2004
Gone with the Wnts: β-Catenin, T-Cell Factor, Forkhead Box O, and Oxidative Stress in Age-Dependent Diseases of Bone, Lipid, and Glucose Metabolism
2007
Extracellular Regulation of BMP Signaling in Vertebrates: A Cocktail of Modulators
2002
Signal Transduction by the TGF-β Superfamily
2002 StandoutScience
The Genetics of Low-Density Lipoprotein Receptor-Related Protein 5 in Bone: A Story of Extremes
2007
The Wnt Antagonist Secreted Frizzled-Related Protein-1 Is a Negative Regulator of Trabecular Bone Formation in Adult Mice
2004
From Estrogen-Centric to Aging and Oxidative Stress: A Revised Perspective of the Pathogenesis of Osteoporosis
2010 Standout
Wnt10b deficiency results in age-dependent loss of bone mass and progressive reduction of mesenchymal progenitor cells
2010
IARC Handbooks of Cancer Prevention
2003
The LRP5 High-Bone-Mass G171V Mutation Disrupts LRP5 Interaction with Mesd
2004
Functional deficiencies of granulocyte-macrophage colony stimulating factor and interleukin-3 contribute to insulitis and destruction of β cells
2007 StandoutNobel
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
2010 StandoutNobel
Decreased BMD and Limb Deformities in Mice Carrying Mutations in Both Lrp5 and Lrp6
2004
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines
2023 StandoutNobel
Antigen Presentation and T Cell Stimulation by Dendritic Cells
2002
Deletion of a Single Allele of the Dkk1 Gene Leads to an Increase in Bone Formation and Bone Mass
2006
Wnt signalling in osteoblasts regulates expression of the receptor activator of NFκB ligand and inhibits osteoclastogenesis in vitro
2006
Oropharyngeal Skeletal Disease Accompanying High Bone Mass and Novel LRP5 Mutation
2005
TOPGAL Mice Show That the Canonical Wnt Signaling Pathway Is Active During Bone Development and Growth and Is Activated by Mechanical Loading In Vitro
2005
Comparison of early nerve cord development in insects and vertebrates
1999
Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes
2014 StandoutNobel
Orally Bioavailable GSK-3α/β Dual Inhibitor Increases Markers of Cellular Differentiation In Vitro and Bone Mass In Vivo
2006
Works of Clayton Small being referenced
Cathepsin S Required for Normal MHC Class II Peptide Loading and Germinal Center Development
1999
Inter-Regulation of Th17 Cytokines and the IL-36 Cytokines In Vitro and In Vivo: Implications in Psoriasis Pathogenesis
2011
Gdf11 Is a Negative Regulator of Chondrogenesis and Myogenesis in the Developing Chick Limb
2001
Phenotype of mice lacking functional Deleted in colorectal cancer (Dec) gene
1997 Nature
mRNA-encoded, constitutively active STINGV155M is a potent genetic adjuvant of antigen-specific CD8+ T cell response
2021
Overlapping roles for granulocyte-macrophage colony-stimulating factor and interleukin-3 in eosinophil homeostasis and contact hypersensitivity
2001
High Bone Mass in Mice Expressing a Mutant LRP5 Gene
2003
Heart and Liver Defects and Reduced Transforming Growth Factor β2 Sensitivity in Transforming Growth Factor β Type III Receptor-Deficient Embryos
2003
Involvement of interleukin-3 in delayed-type hypersensitivity.
1998
Unarmed, tumor-specific monoclonal antibody effectively treats brain tumors
2000