Citation Impact
Citing Papers
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation
2010 Science
The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist
2008 StandoutScience
Stress Hormone-Related Psychopathology: Pathophysiological and Treatment Implications
2001
Different patterns of Ca2+ signals are induced by low compared to high concentrations of P2Y agonists in microglia
2006
Presynaptic Modulation Controlling Neuronal Excitability and Epileptogenesis: Role of Kainate, Adenosine and Neuropeptide Y Receptors
2003
A bacterial pathogen induces developmental slowing by high reactive oxygen species and mitochondrial dysfunction in Caenorhabditis elegans
2023 StandoutNobel
Adenosine triphosphate induces proliferation of human neural stem cells: Role of calcium and p70 ribosomal protein S6 kinase
2003
Neuroinflammation in Parkinson's disease: a target for neuroprotection?
2009 Standout
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
2009 StandoutNature
Adenosine, adenosine A2A antagonists, and Parkinson's disease
2009
Adenosine A2A receptors and brain injury: Broad spectrum of neuroprotection, multifaceted actions and “fine tuning” modulation
2007
Microglia: active sensor and versatile effector cells in the normal and pathologic brain
2007 Standout
P2X7 nucleotide receptor activation enhances IFNγ‐induced type II nitric oxide synthase activity in BV‐2 microglial cells
2003
Hippocampal Interleukin‐1β Gene Expression during Long‐Term Potentiation Decays with Age
2003
Selective inflammatory stimulations enhance release of microglial response factor (MRF)‐1 from cultured microglia
2002
Adenosine receptors and Huntington's disease: implications for pathogenesis and therapeutics
2003
A Crucial Role for Forebrain Adenosine A2A Receptors in Amphetamine Sensitization
2004
Blockade of A2A adenosine receptors prevents basic fibroblast growth factor‐induced reactive astrogliosis in rat striatal primary astrocytes
2003
Neuropathic pain and spinal microglia: a big problem from molecules in ‘small’ glia
2004
Brown and beige fat: development, function and therapeutic potential
2013 Standout
Calcium signaling in microglial cells
2002
Analysis of knockout mice suggests a role for VGF in the control of fat storage and energy expenditure
2009
Molecular Understanding and Modern Application of Traditional Medicines: Triumphs and Trials
2007 Standout
Adenosine receptors in the nervous system: pathophysiological implications
2002
Adenosine A1 and A2A receptors are co-expressed in pyramidal neurons and co-localized in glutamatergic nerve terminals of the rat hippocampus
2005
Inwardly rectifying K+ channels influence Ca2+ entry due to nucleotide receptor activation in microglia
2004
Animal models for the study of adenosine receptor function
2004
Ligand-regulated oligomerization of β2-adrenoceptors in a model lipid bilayer
2009 StandoutNobel
Adenosine receptors as therapeutic targets
2006 Standout
Microglial cell origin and phenotypes in health and disease
2011 Standout
Adenosine A2A receptors and metabotropic glutamate 5 receptors are co‐localized and functionally interact in the hippocampus: a possible key mechanism in the modulation of N‐methyl‐d ‐aspartate effects
2005
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
Pathophysiological roles of extracellular nucleotides in glial cells: differential expression of purinergic receptors in resting and activated microglia
2005
Purinergic receptors modulate MAP kinases and transcription factors that control microglial inflammatory gene expression
2006
An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii
2007 Standout
P2X7 Mediates Superoxide Production in Primary Microglia and Is Up-regulated in a Transgenic Mouse Model of Alzheimer's Disease
2003
Purinergic modulation of microglial cell activation
2006
ATP mediates rapid microglial response to local brain injury in vivo
2005 Standout
Repertoire of microglial and macrophage responses after spinal cord injury
2011 Standout
International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors—An Update
2011 Standout
Expression of Kv1.2 in microglia and its putative roles in modulating production of proinflammatory cytokines and reactive oxygen species
2008
P2X7 receptors in the nervous system
2006
Therapeutic potential of adenosine A2A receptor antagonists in Parkinson's disease
2004
Purinergic mediated changes in Ca2+ mobilization and functional responses in microglia: Effects of low levels of ATP
2005
Adenosine A2A receptor stimulation potentiates nitric oxide release by activated microglia
2005
P2Y and P2X purinoceptor mediated Ca2+ signalling in glial cell pathology in the central nervous system
2002
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Reversed Na+/Ca2+Exchange Contributes to Ca2+Influx and Respiratory Burst in Microglia
2007
Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer’s disease
2018
Cellular Distribution and Functions of P2 Receptor Subtypes in Different Systems
2004
Glutamate efflux from human cerebrocortical slices during ischemia: vesicular-like mode of glutamate release and sensitivity to A2A adenosine receptor blockade
2004
Neurovascular regulation in the normal brain and in Alzheimer's disease
2004 Standout
Pannexin‐1 mediates large pore formation and interleukin‐1β release by the ATP‐gated P2X7 receptor
2006 Standout
Selective expression of Gi/o‐coupled ATP receptor P2Y12 in microglia in rat brain
2003
Age and strain differences in rat place learning and hippocampal dentate gyrus frequency-potentiation
1994
The function of microglia through purinergic receptors: Neuropathic pain and cytokine release
2005
Genetic inactivation of adenosine A2A receptors attenuates acute traumatic brain injury in the mouse cortical impact model
2008
Nonalcoholic Steatohepatitis: Summary of An Aasld Single Topic Conference
2003 Standout
Host microbiota constantly control maturation and function of microglia in the CNS
2015 Standout
Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
2010 StandoutNature
Adenosine A2AReceptors in Bone Marrow-Derived Cells But Not in Forebrain Neurons Are Important Contributors to 3-Nitropropionic Acid-Induced Striatal Damage as Revealed by Cell-Type-Selective Inactivation
2006
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
ATP‐induced chemotaxis of microglial processes requires P2Y receptor‐activated initiation of outward potassium currents
2007
Purinergic receptors on microglial cells: functional expression in acute brain slices and modulation of microglial activation in vitro
2003
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Lysophosphatidylcholine potentiates Ca2+ influx, pore formation and p44/42 MAP kinase phosphorylation mediated by P2X7 receptor activation in mouse microglial cells
2007
Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques
2012 StandoutNobel
Suramin inhibits spinal cord microglia activation and long-term hyperalgesia induced by formalin injection
2004
Decreased adenosine receptor binding in dystonic brains of the dtsz mutant
2005
The epidemiology of Parkinson's disease: risk factors and prevention
2016 Standout
Expression of P2X receptors on rat microglial cells during early development
2005
Adenosine: does it have a neuroprotective role after all?
2000
ATP selectively suppresses the synthesis of the inflammatory protein microglial response factor (MRF)-1 through Ca2+ influx via P2X7 receptors in cultured microglia
2002
The birth and postnatal development of purinergic signalling
2010
Behavioral and electrophysiological correlates of the quinolinic acid rat model of Huntington's disease in rats
1994
LTP and LTD
2004 Standout
Stress-induced immune dysfunction: implications for health
2005 Standout
Small molecule drug screening in Drosophila identifies the 5HT2A receptor as a feeding modulation target
2013 Standout
Mitochondria: A target for bacteria
2015
Light‐Controlled Formation of Vesicles and Supramolecular Organogels by a Cholesterol‐Bearing Amphiphilic Molecular Switch
2014 StandoutNobel
The therapeutic potential of G-protein coupled receptors in Huntington's disease
2010
Involvement of P2X and P2Y receptors in microglial activation in vivo
2007
Environmental Enrichment Reduces Aβ Levels and Amyloid Deposition in Transgenic Mice
2005 Standout
Neurosteroids: biochemistry and clinical significance
2002
Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NFAT
2008
Selective inactivation or reconstitution of adenosine A2A receptors in bone marrow cells reveals their significant contribution to the development of ischemic brain injury
2004
The P2Y12 receptor regulates microglial activation by extracellular nucleotides
2006 StandoutNobel
Modulation of Seizures and Synaptic Plasticity by Adenosinergic Receptors in an Experimental Model of Temporal Lobe Epilepsy Induced by Pilocarpine in Rats
2005
Adenosine receptors as drug targets — what are the challenges?
2013
Lipopolysaccharide‐induced down‐regulation of Ca2+release‐activated Ca2+currents (ICRAC) but not Ca2+‐activated TRPM4‐like currents (ICAN) in cultured mouse microglial cells
2007
CURCUMIN: THE INDIAN SOLID GOLD
2007 Standout
Synaptic Plasticity: Multiple Forms, Functions, and Mechanisms
2007 Standout
Acinetobacter baumannii outer membrane protein A targets the nucleus and induces cytotoxicity
2007
The P2X7Receptor Drives Microglial Activation and Proliferation: A Trophic Role for P2X7R Pore
2009
A Long-Term Study of Istradefylline Safety and Efficacy in Patients With Parkinson Disease
2015
Up-regulation of p2x2, p2x4 receptor and ischemic cell death: prevention by p2 antagonists
2003
Lipid raft microdomains and neurotransmitter signalling
2006
Curcumin: From ancient medicine to current clinical trials
2008 Standout
Can Meditation Slow Rate of Cellular Aging? Cognitive Stress, Mindfulness, and Telomeres
2009 StandoutNobel
Activation of A$_3$ receptors by endogenous adenosine inhibits synaptic transmission during hypoxia in rat cortical neurons
2003
Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects Against Chronic Diseases
2012 Standout
Activation of Presynaptic P2X7-Like Receptors Depresses Mossy Fiber–CA3 Synaptic Transmission through p38 Mitogen-Activated Protein Kinase
2002
Lipids and Alzheimer’s Disease
2020
Structurally Enabled Discovery of Adenosine A2A Receptor Antagonists
2016
Bioavailability of Curcumin: Problems and Promises
2007 Standout
Long-Term Potentiation and Memory
2004
Applications of the Morris water maze in the study of learning and memory
2001 Standout
Purinoceptor expression in regenerating skeletal muscle in the mdx mouse model of muscular dystrophy and in satellite cell cultures
2004
Molecular Physiology of P2X Receptors
2002 Standout
ACTIONS OF ADENOSINE AT ITS RECEPTORS IN THE CNS: Insights from Knockouts and Drugs
2004
Neural plasticity in the ageing brain
2005
Purinergic receptors activating rapid intracellular Ca2+ increases in microglia
2005
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
ATP Mediates Calcium Signaling Between Astrocytes and Microglial Cells: Modulation by IFN-γ
2001
Voltage‐dependent ebselen and diorganochalcogenides inhibition of 45Ca2+ influx into brain synaptosomes
2003
The Chemistry of Reactive Oxygen Species (ROS) Revisited: Outlining Their Role in Biological Macromolecules (DNA, Lipids and Proteins) and Induced Pathologies
2021 Standout
The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders
2011 Standout
A Dual Role of Adenosine A2AReceptors in 3-Nitropropionic Acid-Induced Striatal Lesions: Implications for the Neuroprotective Potential of A2AAntagonists
2003
Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy
2016
About Sleep's Role in Memory
2013 Standout
Extracellular ATP or ADP Induce Chemotaxis of Cultured Microglia through Gi/o-Coupled P2Y Receptors
2001
Involvement of astrocytes in purine‐mediated reparative processes in the brain
2001
Microglial M1/M2 polarization and metabolic states
2015 Standout
Assignment of ecto‐nucleoside triphosphate diphosphohydrolase‐1/cd39 expression to microglia and vasculature of the brain
2000
An alternative to the LTP orthodoxy: a plasticity-pathology continuum model
1996
Synaptic Plasticity and Memory: An Evaluation of the Hypothesis
2000 Standout
Pharmacology of Lazaroids and Brain Energy Metabolism: A Review
1997
Organoselenium and Organotellurium Compounds: Toxicology and Pharmacology
2004 Standout
The Adaptive Brain: Aging and Neurocognitive Scaffolding
2008 Standout
Physiology of Microglia
2011 Standout
Works of Claudio Frank being referenced
Clostridium difficile Toxin B Causes Apoptosis in Epithelial Cells by Thrilling Mitochondria
2007
Effects of adenosinergic drugs on hypoxia-induced electrophysiological changes in rat hippocampal slices
1992
Neuroprotective effects of allopregnenolone on hippocampal irreversible neurotoxicity in vitro
2000
Comparative influence of calcium blocker and purinergic drugs on epileptiform bursting in rat hippocampal slices
1988
Two different ionotropic receptors are activated by ATP in rat microglia
1999
Cholesterol depletion inhibits synaptic transmission and synaptic plasticity in rat hippocampus
2008
Adenosine- and 2-chloro-adenosine-induced cytopathic effects on myoblastic cells and myotubes: involvement of different intracellular mechanisms
2000
Selective reduction of hippocampal dentate frequency potentiation in aged rats with impaired place learning
1994
Curcumin treatment protects rat retinal neurons against excitotoxicity: effect on N-methyl-D-aspartate-induced intracellular Ca2+ increase
2005
TLQP‐21, a neuroendocrine VGF‐derived peptide, prevents cerebellar granule cells death induced by serum and potassium deprivation
2007
Hippocampal long-term potentiation in nucleus basalis magnocellularis-lesioned rats
1992
Protective actions of 21-aminosteroids and MK-801 on hypoxia-induced electrophysiological changes in rat hippocampal slices
1993
Adenosine A2A receptor blockade differentially influences excitotoxic mechanisms at pre‐ and postsynaptic sites in the rat striatum
2004
Cholesterol perturbing agents inhibit NMDA‐dependent calcium influx in rat hippocampal primary culture
2004
Native metastable prefibrillar oligomers are the most neurotoxic species among amyloid aggregates
2014
Adenosine A2A receptors enable the synaptic effects of cannabinoid CB1 receptors in the rodent striatum
2009
Lipid raft disruption protects mature neurons against amyloid oligomer toxicity
2010
Neuroprotective effects of the mGlu5R antagonist MPEP towards quinolinic acid‐induced striatal toxicity: involvement of pre‐ and post‐synaptic mechanisms and lack of direct NMDA blocking activity
2004
The Controversial Role of Adenosine A2A Receptor Antagonists as Neuro-protective Agents
2004
Blockade of Striatal Adenosine A2AReceptor Reduces, through a Presynaptic Mechanism, Quinolinic Acid-Induced Excitotoxicity: Possible Relevance to Neuroprotective Interventions in Neurodegenerative Diseases of the Striatum
2002
Influence of adenosinergic drugs on the epileptiform and neurotoxic effects of N-methyl-d-aspartate: comparison with the effects of MK801.
1994
Modulation of glutamate release and excitotoxicity by adenosine A2Areceptors
2003