Standout Papers
- DNA Joining in Mammalian Cells (1993)
- Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I. (1994)
- Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I (1994)
- Activation of mammalian DNA ligase I through phosphorylation by casein kinase II. (1992)
Citation Impact
Citing Papers
Functional Genomic Analysis of RNA Interference in C. elegans
2005 StandoutScienceNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Feedback Circuit among INK4 Tumor Suppressors Constrains Human Glioblastoma Development
2008
Shortening of 3′UTRs Correlates with Poor Prognosis in Breast and Lung Cancer
2012
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
Enzymes acting at strand interruptions in DNA
1995 StandoutNobel
DNA Ligase IV from HeLa Cell Nuclei
1996 StandoutNobel
Towards a molecular architecture of centriole assembly
2012
Cloning and sequence analysis of a cDNA coding for the murine DNA ligase I enzyme
1994
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
2005 StandoutNature
Mammalian single-strand break repair: Mechanisms and links with chromatin
2006
Specific Function of DNA Ligase I in Simian Virus 40 DNA Replication by Human Cell-free Extracts Is Mediated by the Amino-terminal Non-catalytic Domain
1997 StandoutNobel
Global Analysis of Transcriptional Regulation by Poly(ADP-ribose) Polymerase-1 and Poly(ADP-ribose) Glycohydrolase in MCF-7 Human Breast Cancer Cells
2009
Chromatin Modifications and Their Function
2007 Standout
PARP-3 Is a Mono-ADP-ribosylase That Activates PARP-1 in the Absence of DNA
2010
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Oncogenes and tumour suppressors take on centrosomes
2007
High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis
2013 StandoutNobel
Stu-71air-2 is a C. elegans aurora homologue essential for chromosome segregation during embryonic and post-embryonic development
1999
Purification and Characterization of DNA Ligase III from Bovine Testes
1995
Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA-damaging agents
1992 StandoutNobel
Degradation of Cdc25A by β-TrCP during S phase and in response to DNA damage
2003 StandoutNatureNobel
Mammalian microRNAs predominantly act to decrease target mRNA levels
2010 StandoutNature
Ubiquitin ligases: cell-cycle control and cancer
2006
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3
2005
Telomere Dysfunction Increases Mutation Rate and Genomic Instability
2001 StandoutNobel
The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets
2010
14-3-3σ controls mitotic translation to facilitate cytokinesis
2007 Nature
Deletion Analysis of the Large Subunit p140 in Human Replication Factor C Reveals Regions Required for Complex Formation and Replication Activities
1997
The small GTPase Ran: interpreting the signs
2003
A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy
2006
Mitotic Phosphorylation of Histone H3 Is Governed by Ipl1/aurora Kinase and Glc7/PP1 Phosphatase in Budding Yeast and Nematodes
2000
Importin Beta
2004
Electron Crystal Structure of the Transcription Factor and DNA Repair Complex, Core TFIIH
2000 StandoutNobel
DNA ligase I gene expression during differentiation and cell proliferation
1992
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
The replication factory targeting sequence/PCNA-binding site is required in G1 to control the phosphorylation status of DNA ligase I
1999
Mechanism of Stimulation of Human DNA Ligase I by the Rad9-Rad1-Hus1 Checkpoint Complex
2006 StandoutNobel
The anaphase-promoting complex: it's not just for mitosis any more
2002
The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment
2005
Structure of the human DNA ligast I gene
1992 StandoutNobel
A newly identified DNA ligase of Saccharomyces cerevisiaeinvolved in RAD52-independent repair of DNA double-strand breaks
1997 StandoutNobel
Creation and Removal of Embedded Ribonucleotides in Chromosomal DNA during Mammalian Okazaki Fragment Processing
1997
Translational control by CPEB: a means to the end
2001
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
2004 StandoutNatureNobel
Two Distinct DNA Ligase Activities in Mitotic Extracts of the Yeast Saccharomyces Cerevisiae
1997
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
Altered DNA ligase III activity in the CHO EM9 mutant
1994
Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks
1995 StandoutNobel
DNA ligase I is required for fetal liver erythropoiesis but is not essential for mammalian cell viability
1996
To cycle or not to cycle: a critical decision in cancer
2001
DNA ligases in the repair and replication of DNA
2000
CDC5 and CKII Control Adaptation to the Yeast DNA Damage Checkpoint
1997 StandoutNobel
Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair
1997
Haploinsufficiency of the cdc2l gene contributes to skin cancer development in mice
2007
Human DNA ligase I completely encircles and partially unwinds nicked DNA
2004 Nature
DNA Ligase I and Proliferating Cell Nuclear Antigen Form a Functional Complex
2001
Regulation of HP1–chromatin binding by histone H3 methylation and phosphorylation
2005 Nature
A Key Role for Poly(ADP-Ribose) Polymerase 3 in Ectodermal Specification and Neural Crest Development
2011
CLIP170-like tip1p Spatially Organizes Microtubular Dynamics in Fission Yeast
2000 StandoutNobel
DNA repair
1993 StandoutNobel
The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast
1999
Regulation of the specific DNA binding function of p53
1992
The Survivin-like C. elegans BIR-1 Protein Acts with the Aurora-like Kinase AIR-2 to Affect Chromosomes and the Spindle Midzone
2000 StandoutNobel
Molecular mechanism of nucleotide excision repair
1999
Aurora-kinase inhibitors as anticancer agents
2004
DNA ligase III is the major high molecular weight DNA joining activity in SV40-transformed human fibroblasts: normal levels of DNA ligase III activity in Bloom syndrome cells
1993
Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice
1998 StandoutNobel
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
1999 StandoutNobel
Chromatin Decondensation and Nuclear Reprogramming by Nucleoplasmin
2006
Nuclear Reprogramming in Cells
2008 StandoutScienceNobel
Protein kinase CK2: an enzyme with multiple substrates and a puzzling regulation
1995
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA
2007 StandoutNobel
Expression of active human DNA ligase I in Escherichia coli cells that harbor a full-length DNA ligase I cDNA construct.
1993
Quality Control by DNA Repair
1999 StandoutScienceNobel
Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks
2018
Reticulating 1D Ribbons into 2D Covalent Organic Frameworks by Imine and Imide Linkages
2020 StandoutNobel
AIR-2: An Aurora/Ipl1-related Protein Kinase Associated with Chromosomes and Midbody Microtubules Is Required for Polar Body Extrusion and Cytokinesis in Caenorhabditis elegans Embryos
1998
Snail blocks the cell cycle and confers resistance to cell death
2004
Molecular Cloning and Expression of Human cDNAs Encoding a Novel DNA Ligase IV and DNA Ligase III, an Enzyme Active in DNA Repair and Recombination
1995 StandoutNobel
The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability
2009
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
CDK11p58 is required for the maintenance of sister chromatid cohesion
2007
Functional complementation of xeroderma pigmentosum complementation group E by replication protein A in an in vitro system.
1996 StandoutNobel
On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1
2012 Standout
Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome
2004 StandoutNobel
Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate
2008
Three distinct DNA ligases in mammalian cells.
1991 StandoutNobel
Prophase Destruction of Emi1 by the SCFβTrCP/Slimb Ubiquitin Ligase Activates the Anaphase Promoting Complex to Allow Progression beyond Prometaphase
2003
Assembly, subunit composition, and footprint of human DNA repair excision nuclease
1998 StandoutNobel
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
The N-terminal domain of human DNA ligase I contains the nuclear localization signal and directs the enzyme to sites of DNA replication.
1995
Schizosaccharomyces pombe cdc 20 + encodes DNA polymerase ɛ and is required for chromosomal replication but not for the S phase checkpoint
1997 StandoutNobel
Translating the Histone Code
2001 StandoutScience
Reconstitution of complete SV40 DNA replication with purified replication factors.
1994
The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases
2007
Recombinant replication protein A: expression, complex formation, and functional characterization
1994
Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression
2011
Identification of a specific inhibitor for DNA ligase I in human cells.
1992
Recognition and processing of damaged DNA
1995 StandoutNobel
Commentary: the fission yeast microtubule cytoskeleton
1998
Mammalian DNA ligase II is highly homologous with vaccinia DNA ligase. Identification of the DNA ligase II active site for enzyme-adenylate formation.
1994
Rejoining Kinetics of DNA Single- and Double-Strand Breaks in Normal and DNA Ligase-Deficient Cells after Exposure to Ultraviolet C and Gamma Radiation: An Evaluation of Ligating Activities Involved in Different DNA Repair Processes
1999
An interaction between DNA ligase I and proliferating cell nuclear antigen: Implications for Okazaki fragment synthesis and joining
1997
The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1
2004 StandoutNobel
Removal of oxygen free-radical-induced 5′,8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cells
2000 StandoutNobel
Mammalian DNA Ligase III: Molecular Cloning, Chromosomal Localization, and Expression in Spermatocytes Undergoing Meiotic Recombination
1995
Whose end is destruction: cell division and the anaphase-promoting complex
1999
DNA Ligase I Mediates Essential Functions in Mammalian Cells
1995
Molecular cloning of the human nucleotide-excision-repair gene ERCC4.
1994 StandoutNobel
Cap-Independent Translation Is Required for Starvation-Induced Differentiation in Yeast
2007 StandoutScienceNobel
Works of Claude Prigent being referenced
Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules
2002
The PITSLRE/CDK11 p58 protein kinase promotes centrosome maturation and bipolar spindle formation
2006
Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2–M transition
2004
A FRET biosensor reveals spatiotemporal activation and functions of aurora kinase A in living cells
2016
The Xenopus laevis Aurora-related Protein Kinase pEg2 Associates with and Phosphorylates the Kinesin-related Protein XlEg5
1999
FBXW7/hCDC4 controls glioma cell proliferation in vitro and is a prognostic marker for survival in glioblastoma patients
2007
A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly
2003
DNA ligase I fromXenopus laeviseggs
1991
Expression of DNA ligases I and II during oogenesis and early development of Xenopus laevis
1992
Drosophila Nek2 protein kinase knockdown leads to centrosome maturation defects while overexpression causes centrosome fragmentation and cytokinesis failure
2004
Clockwise or anticlockwise? Turning the centriole triplets in the right direction!
2007
Identification of DNA ligase I related polypeptides in three different human cells
1990
On the role of aurora-A in centrosome function
2002
Aurora kinases, aneuploidy and cancer, a coincidence or a real link?
2005
Reinvestigation of DNA ligase I in axolotl andPleurodelesdevelopment
1991
PARP‐3 associates with polycomb group bodies and with components of the DNA damage repair machinery
2006
The Xenopus laevis Aurora/Ip11p-Related Kinase pEg2 Participates in the Stability of the Bipolar Mitotic Spindle
2000
Aurora B -TACC1 protein complex in cytokinesis
2004
TACC1–chTOG–Aurora A protein complex in breast cancer
2003
APC/Fizzy‐Related targets Aurora‐A kinase for proteolysis
2002
Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I
1994 StandoutNobel
Progesterone regulates the accumulation and the activation of Eg2 kinase in Xenopus oocytes
2000
Proteomic Investigation of Phosphorylation Sites in Poly(ADP-ribose) Polymerase-1 and Poly(ADP-ribose) Glycohydrolase
2008
Phosphorylation of serine 10 in histone H3, what for?
2003
Activation of mammalian DNA ligase I through phosphorylation by casein kinase II.
1992 StandoutNobel
The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly
1998
Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I.
1994 StandoutNobel
Aurora/Ipl1p-related kinases, a new oncogenic family of mitotic serine-threonine kinases
1999