Standout Papers
Citation Impact
Citing Papers
Drosophila melanogaster Is a Genetically Tractable Model Host for Mycobacterium marinum
2003
Overexpression of a pattern-recognition receptor, peptidoglycan-recognition protein-LE, activates imd/relish-mediated antibacterial defense and the prophenoloxidase cascade in Drosophila larvae
2002
Activation of Drosophila Toll During Fungal Infection by a Blood Serine Protease
2002 StandoutScienceNobel
Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility
2003 StandoutNobel
Two Proteases Defining a Melanization Cascade in the Immune System of Drosophila
2006
A Ubiquitin-Proteasome Pathway Represses the Drosophila Immune Deficiency Signaling Cascade
2002
Nitric oxide contributes to induction of innate immune responses to gram-negative bacteria in Drosophila
2003
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
2001 StandoutNature
Crystal structure of peptidoglycan recognition protein LB from Drosophila melanogaster
2003
Inflammation and metabolic disorders
2006 StandoutNature
Gout-associated uric acid crystals activate the NALP3 inflammasome
2006 StandoutNature
A Drosophila IκB kinase complex required for Relish cleavage and antibacterial immunity
2000
Hemolymph‐dependent and ‐independent responses in Drosophila immune tissue
2004
Toll-like Receptors and Innate Immunity
2001
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
Drosophila immunity: two paths to NF-κB
2001
Toll signaling pathways in the innate immune response
2000
A family of proteins related to Spätzle, the toll receptor ligand, are encoded in the Drosophila genome
2001
The Rel Protein DIF Mediates the Antifungal but Not the Antibacterial Host Defense in Drosophila
2000 StandoutNobel
Toll signaling: the enigma variations
2000
Evolution of enzyme cascades from embryonic development to blood coagulation
2002
Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections
2001 StandoutNobel
Gram-negative Bacteria-binding Protein, a Pattern Recognition Receptor for Lipopolysaccharide and β-1,3-Glucan That Mediates the Signaling for the Induction of Innate Immune Genes in Drosophila melanogaster Cells
2000
Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling
2003 StandoutNobel
Role of Drosophila IKKγ in a Toll-independent antibacterial immune response
2000 StandoutNobel
The Toll and Imd pathways are the major regulators of the immune response in Drosophila
2002
Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells
2001
NF-κB signaling pathways in mammalian and insect innate immunity
2001
Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila
2005 StandoutNobel
New insights into Drosophila larval haemocyte functions through genome-wide analysis
2005
Toll-like receptors in the induction of the innate immune response
2000 StandoutNature
A Drosophila Pattern Recognition Receptor Contains a Peptidoglycan Docking Groove and Unusual L,D-Carboxypeptidase Activity
2004 Nobel
Peptidomic and proteomic analyses of the systemic immune response of Drosophila
2004 StandoutNobel
Drosophila immunity: paths and patterns
2003
Drosophila innate immunity: an evolutionary perspective
2002 StandoutNobel
The immune response of Drosophila
2003 StandoutNatureNobel
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Bacterial recognition and signalling by the Drosophila IMD pathway
2005
Toll receptors in innate immunity
2001 StandoutNobel
The immune response of Drosophila melanogaster
2004
Drosophila Immunity: A Large-Scale In Vivo RNAi Screen Identifies Five Serine Proteases Required for Toll Activation
2006
Drosophila Immune Deficiency (IMD) Is a Death Domain Protein that Activates Antibacterial Defense and Can Promote Apoptosis
2001 StandoutNobel
Tehao functions in the Toll pathway in Drosophila melanogaster : possible roles in development and innate immunity
2001
An Immune-Responsive Serpin Regulates the Melanization Cascade in Drosophila
2002
Drosophila melanogasterAntimicrobial Defense
2003 StandoutNobel
Peptidoglycan recognition protein (PGRP)‐LE and PGRP‐LC act synergistically in Drosophila immunity
2004
Tip of another iceberg: Drosophila serpins
2005
Toll-like receptors: critical proteins linking innate and acquired immunity
2001 Standout
Microarray Analysis and Organization of Circadian Gene Expression in Drosophila
2001 StandoutNobel
Peptidoglycan Recognition Proteins Involved in 1,3-β-D-Glucan-dependent Prophenoloxidase Activation System of Insect
2004
The evolution and genetics of innate immunity
2001 StandoutNobel
JNK Signaling Pathway Is Required for Efficient Wound Healing in Drosophila
2002
Sensing infection in Drosophila: Toll and beyond
2004 StandoutNobel
Downregulation of lipopolysaccharide response in drosophila by negative crosstalk between the AP1 and NF-κB signaling modules
2005
Toll-like receptors and innate immunity
2009
The role of Toll-like receptors in host defense against microbial infection
2001
Antimicrobial peptides of multicellular organisms
2002 StandoutNature
Two ways to survive infection: what resistance and tolerance can teach us about treating infectious diseases
2008
Tissue and stage-specific expression of the Tolls in Drosophila embryos
2002 StandoutNobel
Antifungal defense in drosophila
2007 StandoutNobel
Proteomic Analysis of the Systemic Immune Response of Drosophila
2003
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Pathogen Recognition and Innate Immunity
2006 Standout
How Drosophila combats microbial infection: a model to study innate immunity and host–pathogen interactions
2002
Signaling mechanisms in the antimicrobial host defense of Drosophila
2000
Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein
2001 StandoutNatureNobel
Toll-like receptors and innate immunity
2001 Standout
Critical evaluation of the role of the Toll‐like receptor 18‐Wheeler in the host defense of Drosophila
2002
Toll-Like Receptors
2003 Standout
Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays
2001
Serpin Structure, Mechanism, and Function
2002 Standout
Tissue-Specific Inducible Expression of Antimicrobial Peptide Genes in Drosophila Surface Epithelia
2000 StandoutNobel
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
Toll‐like receptor 9 binds single‐stranded CpG‐DNA in a sequence‐ and pH‐dependent manner
2004
A proteomic approach for the analysis of instantly released wound and immune proteins in Drosophila melanogaster hemolymph
2004
Analysis of Homologous Gene Clusters inCaenorhabditis elegansReveals Striking Regional Cluster Domains
2005
Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
2005 StandoutNobel
The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments
2009 Standout
A genome-wide analysis of immune responses in Drosophila
2001 StandoutNobel
The interleukin-1 receptor/Toll-like receptor superfamily: signal generators for pro-inflammatory interleukins and microbial products
2000
A Spätzle-Processing Enzyme Required for Toll Signaling Activation in Drosophila Innate Immunity
2006
Dual Activation of the Drosophila Toll Pathway by Two Pattern Recognition Receptors
2003 StandoutScienceNobel
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
Immune-Deficient Drosophila melanogaster: A Model for the Innate Immune Response to Human Fungal Pathogens
2004
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
Multimerization and interaction of Toll and Spätzle in Drosophila
2004
Fibrinogen Stimulates Macrophage Chemokine Secretion Through Toll-Like Receptor 4
2001
Toll-related receptors and the control of antimicrobial peptide expression inDrosophila
2000 StandoutNobel
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
2006 StandoutNobel
Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis
2006 StandoutNobel
The Host Defense of Drosophila melanogaster
2007 StandoutNobel
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
2004 StandoutNobel
Constitutive expression of a complement-like protein in Toll and JAK gain-of-function mutants ofDrosophila
2000 StandoutNobel
Drosophila peptidoglycan recognition protein LC (PGRP-LC) acts as a signal-transducing innate immune receptor
2005
Innate Immune Recognition
2002 Standout
Drosophila : The Genetics of Innate Immune Recognition and Response
2004
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of Clare Green being referenced
Differential susceptibility of PCR reactions to inhibitors: an important and unrecognised phenomenon
2008
Constitutive Activation of Toll-Mediated Antifungal Defense in Serpin-Deficient Drosophila
1999 StandoutScienceNobel
Drosophila necroticmutations mirror disease-associated variants of human serpins
2003
The necrotic Gene in Drosophila Corresponds to One of a Cluster of Three Serpin Transcripts Mapping at 43A1.2
2000