Citation Impact
Citing Papers
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist
2004 StandoutNobel
Basal Cell Carcinomas in Mice Overexpressing Sonic Hedgehog
1997 StandoutScience
Interaction of Hydroxylated Collagen IV with the von Hippel-Lindau Tumor Suppressor
2007 StandoutNobel
Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein
2000 StandoutNobel
Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
2010 StandoutNobel
The Xenopus Oocyte as a Surrogate Secretory System The Specificity of Protein Export
1980 StandoutNobel
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
1993 Standout
Current Approaches to Primary Therapy for Papillary and Follicular Thyroid Cancer
2001 Standout
The pressure rises: update on the genetics of phaeochromocytoma
2002
Von Hippel‐Lindau gene alterations in sporadic benign and malignant pheochromocytomas
2003
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
2004 StandoutNobel
Spermidine/Spermine-N1-Acetyltransferase 2 Is an Essential Component of the Ubiquitin Ligase Complex That Regulates Hypoxia-inducible Factor 1α
2007 StandoutNobel
Molecular basis of the VHL hereditary cancer syndrome
2002 StandoutNobel
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
A genetic model for colorectal tumorigenesis
1990 Standout
Hereditary paraganglioma targets diverse paraganglia: Table 1
2002
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Gene Mutations in the Succinate Dehydrogenase Subunit SDHB Cause Susceptibility to Familial Pheochromocytoma and to Familial Paraganglioma
2001 Standout
Oxygen sensing by HIF hydroxylases
2004 StandoutNobel
APC mutations occur early during colorectal tumorigenesis
1992 StandoutNature
Oncogenic pathway signatures in human cancers as a guide to targeted therapies
2005 StandoutNature
Novel succinate dehydrogenase subunit B (SDHB) mutations in familial phaeochromocytomas and paragangliomas, but an absence of somatic SDHB mutations in sporadic phaeochromocytomas
2003
Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
1991 StandoutNature
Genomic organization and precise physical location of protein phosphatase 2A regulatory subunit A beta isoform gene on chromosome band 11q23
1998
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
2015 StandoutNobel
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Synthetic peptides define critical contacts between elongin C, elongin B, and the von Hippel-Lindau protein
1999 StandoutNobel
Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor
2004 StandoutNobel
Regulation of angiogenesis by hypoxia: role of the HIF system
2003 StandoutNobel
Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A
1993 Nature
Immunity, Inflammation, and Cancer
2010 Standout
Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret
1994 StandoutNature
Hereditary Colorectal Cancer
2003 Standout
Vitamin D3and Calcium to Prevent Hip Fractures in Elderly Women
1992 Standout
The Effect of Vitamin D Supplementation on Vitamin D Status and Parathyroid Function in Elderly Subjects*
1988
Mechanism of folding chamber closure in a group II chaperonin
2010 StandoutNatureNobel
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
1993 Standout
Principles of protein folding, misfolding and aggregation
2004
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Differential Genetic Alterations in von Hippel-Lindau Syndrome-Associated and Sporadic Pheochromocytomas1
2000
Hypermutability and mismatch repair deficiency in RER+ tumor cells
1993 StandoutNobel
Comparative Genomic Hybridization for Molecular Cytogenetic Analysis of Solid Tumors
1992 StandoutScience
Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing
1983 StandoutNature
Active multi-subunit ACh receptor assembled by translation of heterologous mRNA in Xenopus oocytes
1981 StandoutNatureNobel
von Hippel-Lindau Disease
2006 StandoutNobel
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
2006 StandoutNature
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
2002 StandoutNobel
Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products
1982 StandoutNature
Kinase requirements in human cells: III. Altered kinase requirements inVHL−/− cancer cells detected in a pilot synthetic lethal screen
2008 StandoutNobel
The von Hippel-Lindau Tumor Suppressor Gene
2020
pVHL 19 is a biologically active product of the von Hippel–Lindau gene arising from internal translation initiation
1998 StandoutNobel
Immunoreactive calcitonin in the intermediate lobe of the pituitary gland
1978 Nobel
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Linkage of Early-Onset Familial Breast Cancer to Chromosome 17q21
1990 StandoutScience
Metabolic reprogramming and cancer progression
2020 StandoutScience
Structure of an HIF-1α-pVHL Complex: Hydroxyproline Recognition in Signaling
2002 StandoutScienceNobel
Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma Cells
1993 StandoutScienceNobel
Cancer Genome Landscapes
2013 StandoutScience
Calcitonin Messenger RNA Encodes Multiple Polypeptides in a Single Precursor
1981 Science
Mutations in the RET proto-oncogene and the von Hippel-Lindau disease tumour suppressor gene in sporadic and syndromic phaeochromocytomas.
1995
Mutations in SDHD , a Mitochondrial Complex II Gene, in Hereditary Paraganglioma
2000 StandoutScience
Role ofVHLGene Mutation in Human Cancer
2004 StandoutNobel
The Molecular Basis of Von Hippel-Lindau Disease
1997 StandoutNobel
Works of C.J.M. Lips being referenced
Genotype‐phenotype correlation in multiple endocrine neoplasia type 2: report of the International RET Mutation Consortium
1995
Role of islet amyloid in type 2 diabetes mellitus: consequence or cause?
2002
Multiple endocrine neoplasia syndrome type 2: The value of screening and central registration
1987
Development of multiple endocrine neoplasia type 2A does not involve substantial deletions of chromosome 10
1989
Mapping of the gene encoding the B56β subunit of protein phosphatase 2A (PPP2R5B) to a 0.5-Mb region of chromosome 11q13 and its exclusion as a candidate gene for multiple endocrine neoplasia type 1 (MEN1)
1997
Enolase isozymes in differentiated and undifferentiated medullary thyroid carcinomas
1985
Clinical Implications of Estimation of Intact Parathyroid Hormone (PTH) Versus Total Immunoreactive PTH in Normal Subjects and Hyperparathyroid Patients*
1986
Extensive mutation scanning of RET in sporadic medullary thyroid carcinoma and of RET and VHL in sporadic pheochromocytoma reveals involvement of these genes in only a minority of cases.
1996
COMMON PRECURSOR MOLECULE AS ORIGIN FOR THE ECTOPIC-HORMONE-PRODUCING-TUMOUR SYNDROME
1978