Citation Impact
Citing Papers
Combination Therapy Targeting the Chk1 and Wee1 Kinases Shows Therapeutic Efficacy in Neuroblastoma
2012
Cytoplasmic steps of peptidoglycan biosynthesis
2008
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Integrative genomic mining for enzyme function to enable engineering of a non-natural biosynthetic pathway
2015 StandoutNobel
Autocatalytic association of proteins by covalent bond formation: a Bio Molecular Welding toolbox derived from a bacterial adhesin
2017
Theoretical Study of Molecular Recognition by Hoechst 33258 Derivatives
2005
DNA-binding drugs caught in action: the latest 3D pictures of drug-DNA complexes
2008
Peptidoglycan structure and architecture
2008 Standout
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Acetohydroxyacid synthase and its role in the biosynthetic pathway for branched-chain amino acids
2006
Sugar and pH dual-responsive mesoporous silica nanocontainers based on competitive binding mechanisms
2014 StandoutNobel
Directed evolution: new parts and optimized function
2009 StandoutNobel
Marine natural products
1990 Standout
Pushing product formation to its limit: Metabolic engineering of Corynebacterium glutamicum for l-leucine overproduction
2013
Molecular dynamics simulations of G-DNA and perspectives on the simulation of nucleic acid structures
2012
Isopeptide bond in collagen- and fibrinogen-binding MSCRAMMs
2016
Industrial applications of enzyme biocatalysis: Current status and future aspects
2015
Mononuclear Fe(ii)-N4Py complexes in oxidative DNA cleavage: structure, activity and mechanism
2010 StandoutNobel
Macrophages in atherosclerosis: a dynamic balance
2013 Standout
Microbial production of advanced transportation fuels in non-natural hosts
2009
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
The Regulation of Sulfur Metabolism in Mycobacterium tuberculosis
2011 StandoutNobel
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Illumination of growth, division and secretion by metabolic labeling of the bacterial cell surface
2015 StandoutNobel
Natural Product Hybrids as New Leads for Drug Discovery
2003 Standout
Templated Ligand Assembly by Using G‐Quadruplex DNA and Dynamic Covalent Chemistry
2004
WEE1 murine deficiency induces hyper-activation of APC/C and results in genomic instability and carcinogenesis
2014
The application of DNA and RNA G-quadruplexes to therapeutic medicines
2011
A Catalytic Asymmetric 6 π Electrocyclization: Enantioselective Synthesis of 2‐Pyrazolines
2009 StandoutNobel
Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase
2011
Structural studies of atom-specific anticancer drugs acting on DNA
1999
Waste biorefinery models towards sustainable circular bioeconomy: Critical review and future perspectives
2016 Standout
Supramolecular DNA recognition
2006
Morpholylureas are a new class of potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase (AKR1C3)
2014
Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond
2019 Standout
Recent achievements in developing the biocatalytic toolbox for chiral amine synthesis
2014
Engineering synthetic recursive pathways to generate non-natural small molecules
2012
G‐Quartets 40 Years Later: From 5′‐GMP to Molecular Biology and Supramolecular Chemistry
2004
Design, synthesis and SAR of thienopyridines as potent CHK1 inhibitors
2010
Decellularization of tissues and organs
2006 Standout
A Synthetic Recursive “+1” Pathway for Carbon Chain Elongation
2012
Selenium incorporation using recombinant techniques
2010
The Biosynthetic Logic of Polyketide Diversity
2009 Standout
Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter
2005
Evolution in Action: Plants Resistant to Herbicides
2010 Standout
Quadruplex DNA: sequence, topology and structure
2006 Standout
targetTB: A target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis
2008
Iron Catalysis in Organic Synthesis
2015 Standout
Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
2003 Standout
Supramolecular Coordination: Self-Assembly of Finite Two- and Three-Dimensional Ensembles
2011 Standout
Role of indoleamine 2,3-dioxygenase in health and disease
2015
Photoexpulsion of Surface-Grafted Ruthenium Complexes and Subsequent Release of Cytotoxic Cargos to Cancer Cells from Mesoporous Silica Nanoparticles
2013 StandoutNobel
Challenges in the Discovery of Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors
2015
A study of the reactivity of S(VI)–F containing warheads with nucleophilic amino-acid side chains under physiological conditions
2017
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
Structural Studies of Cytotoxic Marine Alkaloids: Synthesis of Novel Ring-E Analogues of Ascididemin and their in vitro and in vivo Biological Evaluation
2000
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 2. Explicit Solvent Particle Mesh Ewald
2013 Standout
Biosynthesis of Pentangular Polyphenols: Deductions from the Benastatin and Griseorhodin Pathways
2007
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Antimicrobial Resistance in Neisseria gonorrhoeae in the 21st Century: Past, Evolution, and Future
2014 Standout
Dynamic Combinatorial Chemistry
2006 Standout
Directed Evolution of Methanococcus jannaschii Citramalate Synthase for Biosynthesis of 1-Propanol and 1-Butanol by Escherichia coli
2008
Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
2012 Standout
Technology development for the production of biobased products from biorefinery carbohydrates—the US Department of Energy’s “Top 10” revisited
2010 Standout
Rational recognition of nucleic acid sequences
1999
Online structure-based screening of purchasable approved drugs and natural compounds: retrospective examples of drug repositioning on cancer targets
2018
The development of anticancer ruthenium(ii ) complexes: from single molecule compounds to nanomaterials
2017 Standout
Synthesis, Biological Properties, and Molecular Modeling Investigations of Novel 3,4-Diarylpyrazolines as Potent and Selective CB1 Cannabinoid Receptor Antagonists
2003
Unlocking Reactivity of TrpB: A General Biocatalytic Platform for Synthesis of Tryptophan Analogues
2017 StandoutNobel
Molecular Docking: Shifting Paradigms in Drug Discovery
2019 Standout
Non-quinolone Inhibitors of Bacterial Type IIA Topoisomerases: A Feat of Bioisosterism
2013
Helicenes: Synthesis and Applications
2011 Standout
Cofactor specificity motifs and the induced fit mechanism in class I ketol-acid reductoisomerases
2015 StandoutNobel
Structure-Based Design, Synthesis, and Biological Evaluation of Potent and Selective Macrocyclic Checkpoint Kinase 1 Inhibitors
2007
Synthetic Biology and Metabolic Engineering Approaches To Produce Biofuels
2013
Artificial Molecular Machines
2015 Standout
anti-Tuberculosis natural products: synthesis and biological evaluation of pyridoacridine alkaloids related to ascididemin
2010
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
Discovery, Engineering, and Synthetic Application of Transaminase Biocatalysts
2017
A Chiral Wedge Molecule Inhibits Telomerase Activity
2010
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Phase II Study of WEE1 Inhibitor AZD1775 Plus Carboplatin in Patients With TP53-Mutated Ovarian Cancer Refractory or Resistant to First-Line Therapy Within 3 Months
2016
Esterase- and pH-responsive poly(β-amino ester)-capped mesoporous silica nanoparticles for drug delivery
2015 StandoutNobel
Multimerization of an Alcohol Dehydrogenase by Fusion to a Designed Self-Assembling Protein Results in Enhanced Bioelectrocatalytic Operational Stability
2019 StandoutNobel
Asymmetric Enzymatic Synthesis of Allylic Amines: A Sigmatropic Rearrangement Strategy
2016 StandoutNobel
Oxime Ligation on the Surface of Mesoporous Silica Nanoparticles
2015 StandoutNobel
OPLS3: A Force Field Providing Broad Coverage of Drug-like Small Molecules and Proteins
2015 Standout
Intramolecular Michael-type addition of azadienes to 1,4-naphthoquinones instead of Aza-Diels–Alder cycloaddition: a synthesis of ascididemin
2002
Heterocyclic Nanographenes and Other Polycyclic Heteroaromatic Compounds: Synthetic Routes, Properties, and Applications
2016 Standout
Metal–Organic Frameworks and Self-Assembled Supramolecular Coordination Complexes: Comparing and Contrasting the Design, Synthesis, and Functionality of Metal–Organic Materials
2012 Standout
Expanding metabolism for biosynthesis of nonnatural alcohols
2008
Cyclic Tetrapeptides from Nature and Design: A Review of Synthetic Methodologies, Structure, and Function
2019
Works of C.J. Squire being referenced
In Vitro Studies with Methylproamine
2004
Defining the Potassium Binding Region in an Apple Terpene Synthase
2009
Structure and Inhibition of the Human Cell Cycle Checkpoint Kinase, Wee1A Kinase
2005
Crystal Structures of Three Classes of Non-Steroidal Anti-Inflammatory Drugs in Complex with Aldo-Keto Reductase 1C3
2012
Structure ofEscherichia coliUDP-N-acetylmuramoyl:L -alanine ligase (MurC)
2006
Synthesis and structure–activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of the Wee1 and Chk1 checkpoint kinases
2008
Designer DNA-Binding Drugs: The Crystal Structure of a Meta-Hydroxy Analogue of Hoechst 33258 Bound to d(CGCGAATTCGCG)2
1996
The high-resolution crystal structure of a parallel intermolecular DNA G-4 quadruplex/drug complex employing syn glycosyl linkages
2012
Crystallization and preliminary X-ray analysis of α-isopropylmalate synthase fromMycobacterium tuberculosis
2004
Synthesis and structure–activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases
2007
The 1.65 Å resolution structure of the complex of AZD4547 with the kinase domain of FGFR1 displays exquisite molecular recognition
2015
Discovery and characterisation of hydrazines as inhibitors of the immune suppressive enzyme, indoleamine 2,3-dioxygenase 1 (IDO1)
2013
A Convenient New Route to 4-Substituted Benzo[de][3,6]Phenanthrolin-6(6H)-Ones: Important Intermediates in the Synthesis of Ring-A Analogues of the Cytotoxic Marine Alkaloid Ascididemin
1999
High-Resolution Crystal Structure of Plant Carboxylesterase AeCXE1, from Actinidia eriantha, and Its Complex with a High-Affinity Inhibitor Paraoxon,
2007
Autocatalytically generated Thr-Gln ester bond cross-links stabilize the repetitive Ig-domain shaft of a bacterial cell surface adhesin
2013
Crystal structure of LeuA from Mycobacterium tuberculosis , a key enzyme in leucine biosynthesis
2004
Structure of the First Parallel DNA Quadruplex-Drug Complex
2003
Crystal and NMR Structures of a Peptidomimetic β‐Turn That Provides Facile Synthesis of 13‐Membered Cyclic Tetrapeptides
2017
Use of ω-Transaminase Enzyme Chemistry in the Synthesis of a JAK2 Kinase Inhibitor
2013
Efficient Synthesis of (S)-1-(5-Fluoropyrimidin-2-yl)ethylamine Using an ω-Transaminase Biocatalyst in a Two-Phase System
2013
Self-generated covalent cross-links in the cell-surface adhesins of Gram-positive bacteria
2015