Citation Impact
Citing Papers
Regulation of Spontaneous Intestinal Tumorigenesis Through the Adaptor Protein MyD88
2007 Science
Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice
2021 StandoutScienceNobel
Adenomatous polyposis coli‐deficient zebrafish are susceptible to digestive tract neoplasia
2006
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
Immunomodulatory Function of Interleukin 28B During Primary Infection With Cytomegalovirus
2014 StandoutNobel
Four-component protein nanocages designed by programmed symmetry breaking
2024 StandoutNatureNobel
CYCLE Is a Second bHLH-PAS Clock Protein Essential for Circadian Rhythmicity and Transcription of Drosophila period and timeless
1998 StandoutNobel
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis
1999
APC gene mutations and colorectal adenomatosis in familial adenomatous polyposis
2000
Molecular genetics of implantation in the mouse
1997
Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development
1999
Memory CD8 T cells mediate severe immunopathology following respiratory syncytial virus infection
2018
Inflammation and cancer
2002 StandoutNature
β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
1999 StandoutNature
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
The role of cyclooxygenases in inflammation, cancer, and development
1999
TCF transcription factors: molecular switches in carcinogenesis
1999
Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function
2010
NF-κB in cancer: from innocent bystander to major culprit
2002 Standout
Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer
2005
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia
1995
Programmable RNA Tracking in Live Cells with CRISPR/Cas9
2016 StandoutNobel
A Mutant Drosophila Homolog of Mammalian Clock Disrupts Circadian Rhythms and Transcription of period and timeless
1998 StandoutNobel
Inducible in vivo genome editing with CRISPR-Cas9
2015
Positional Cloning of the Mouse Circadian Gene
1997
Type I interferons in infectious disease
2015 Standout
Alleles of the APC gene: An attenuated form of familial polyposis
1993
Suppression of intestinal neoplasia by DNA hypomethylation
1995
APC mutations occur early during colorectal tumorigenesis
1992 StandoutNature
The Hallmarks of Cancer
2000 Standout
Lessons from Hereditary Colorectal Cancer
1996 Standout
Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells
2014 StandoutNobel
The Intestinal Wnt/TCF Signature
2006
Viral and cellular mRNA capping: Past and prospects
2000
Gene function in mouse embryogenesis: get set for gastrulation
2007
Microbes and Colorectal Cancer: Is There a Relationship?
2009
Mechanisms of carcinogenesis and the mutant mouse
1996
Effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine on intestinal polyp development in ApcΔ716 knockout mice
1996
COX-2 and colon cancer
1998
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling
2002
Osteoclast differentiation and activation
2003 StandoutNature
Mutations of theAPC adenomatous polyposis coli) gene
1993
Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)
1996 Standout
IL-28A, IL-28B, and IL-29: Promising cytokines with type I interferon-like properties
2010
Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry
2007 StandoutNatureNobel
Wnt/β-Catenin Signaling in Development and Disease
2006 Standout
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
2005 Nature
An essential role for the IL-2 receptor in Treg cell function
2016
The gut microbiota — masters of host development and physiology
2013 Standout
Microarray Analysis and Organization of Circadian Gene Expression in Drosophila
2001 StandoutNobel
EphB receptor activity suppresses colorectal cancer progression
2005 Nature
A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
2009
Removing the Vertebrate-Specific TBP N Terminus Disrupts Placental β2m-Dependent Interactions with the Maternal Immune System
2002 StandoutNobel
Cancer-related inflammation
2008 StandoutNature
Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse
1993
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
2009 StandoutNature
The genetic basis of colorectal cancer: Insights into critical pathways of tumorigenesis
2000
Identification of stem cells in small intestine and colon by marker gene Lgr5
2007 StandoutNature
Parallels among positive-strand RNA viruses, reverse-transcribing viruses and double-stranded RNA viruses
2006
Interferon-λ Contributes to Innate Immunity of Mice against Influenza A Virus but Not against Hepatotropic Viruses
2008
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
1998
Tumors and inflammatory infiltrates: Friends or foes?
2002
Mammalian DNA Mismatch Repair
1999
The Von Hippel-Lindau Tumor Suppressor Gene and Kidney Cancer
2004 StandoutNobel
APC mutations in colorectal tumors with mismatch repair deficiency.
1996
Mbd4 inactivation increases C→T transition mutations and promotes gastrointestinal tumor formation
2002
Adding the Third Dimension to Virus Life Cycles: Three-Dimensional Reconstruction of Icosahedral Viruses from Cryo-Electron Micrographs
2000
Virus-Induced Transient Immune Suppression and the Inhibition of T Cell Proliferation by Type I Interferon
2011
The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon
2002
Antioncogenes and human cancer.
1993
Wnt signaling and cancer
2000 Standout
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
Independent Photoreceptive Circadian Clocks Throughout Drosophila
1997 StandoutScienceNobel
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice.
1999
PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance
2010 StandoutNobel
Innate Immune Inflammatory Response against Enteric Bacteria Helicobacter hepaticus Induces Mammary Adenocarcinoma in Mice
2006
Adding the Third Dimension to Virus Life Cycles: Three-Dimensional Reconstruction of Icosahedral Viruses from Cryo-Electron Micrographs
1999
Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene.
1995
Evidence against dominant negative mechanisms of intestinal polyp formation by Apc gene mutations.
1995
Microbiota, Disease, and Back to Health: A Metastable Journey
2012
beta-Catenin associates with the actin-bundling protein fascin in a noncadherin complex.
1996 StandoutNobel
Myofibroblasts. II. Intestinal subepithelial myofibroblasts
1999
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Inflammatory Bowel Disease and Adenomas in Mice Expressing a Dominant Negative N-Cadherin
1995 Science
Mutation ofPten/Mmac1in mice causes neoplasia in multiple organ systems
1999
Genetic control of blood pressure and the angiotensinogen locus.
1995 StandoutNobel
Epiregulin Is Not Essential for Development of Intestinal Tumors but Is Required for Protection from Intestinal Damage
2004
APC binds to the novel protein EB1.
1995
Vitamin B 2 -based blue-light photoreceptors in the retinohypothalamic tract as the photoactive pigments for setting the circadian clock in mammals
1998 StandoutNobel
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 StandoutNobel
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
The chromosomal distribution of mouse odorant receptor genes.
1996 StandoutNobel
Biallelic inactivation of hMLH 1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
1998 StandoutNobel
A Genetic Linkage Map of the Mouse: Current Applications and Future Prospects
1993 Science
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Differential regulation of mammalian Period genes and circadian rhythmicity by cryptochromes 1 and 2
1999 StandoutNobel
Dysregulation of the TSC-mTOR pathway in human disease
2004 Standout
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
Specific 5'-GGGA-3'-->5'-GGA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
1995
Pathologic progression of autochthonous prostate cancer in the TRAMP model
1999
Apoptosis and APC in colorectal tumorigenesis.
1996
Synergy Between Tumor Suppressor APC and the β-Catenin-Tcf4 Target Tcf1
1999 Science
MSH2 deficiency contributes to accelerated APC-mediated intestinal tumorigenesis.
1996
Association of the APC Tumor Suppressor Protein with Catenins
1993 Science
Works of Cindy Luongo being referenced
Binding Site for S-Adenosyl-l-methionine in a Central Region of Mammalian Reovirus λ2 Protein
1998
Elevated cyclooxygenase-2 levels in Min mouse adenomas
1996
Studies of neoplasia in the Min mouse1C57BL/6J Min/+ mice are available worldwide from The Jackson Laboratory, Bar Harbor, ME 04609, USA.1
1997
The Adenomatous Polyposis Coli Gene of the Mouse in Development and Neoplasia
1994
ApcMin: A mouse model for intestinal and mammary tumorigenesis
1995
Homozygosity for the Minallele of Apc results in disruption of mouse development prior to gastrulation
1995
Identification of the Guanylyltransferase Region and Active Site in Reovirus mRNA Capping Protein λ2
2000
Mapping of Multiple Intestinal Neoplasia (Min) to Proximal Chromosome 18 of the Mouse
1993
Localization of a C-terminal region of lambda2 protein in reovirus cores
1997
Loss of Apc+ in intestinal adenomas from Min mice.
1994
Genetic Evaluation of Candidate Genes for the Mom1 Modifier of Intestinal Neoplasia in Mice
1996
A Chimeric A2 Strain of Respiratory Syncytial Virus (RSV) with the Fusion Protein of RSV Strain Line 19 Exhibits Enhanced Viral Load, Mucus, and Airway Dysfunction
2009
Concurrent overexpression of cyclin D1 and cyclin-dependent kinase 4 (Cdk4) in intestinal adenomas from multiple intestinal neoplasia (Min) mice and human familial adenomatous polyposis patients.
1997
Somatic mutational mechanisms involved in intestinal tumor formation in Min mice.
1997
Nonstructural Proteins 1 and 2 of Respiratory Syncytial Virus Suppress Maturation of Human Dendritic Cells
2008
Intestinal neoplasia in the ApcMin mouse: independence from the microbial and natural killer (beige locus) status.
1997
Multiple Intestinal Neoplasia Caused by a Mutation in the Murine Homolog of the APC Gene
1992 Science
Alpha and Lambda Interferon Together Mediate Suppression of CD4 T Cells Induced by Respiratory Syncytial Virus
2006