Citation Impact
Citing Papers
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
Vascular Klotho Deficiency Potentiates the Development of Human Artery Calcification and Mediates Resistance to Fibroblast Growth Factor 23
2012 Standout
Munc18-1 binds directly to the neuronal SNARE complex
2007 StandoutNobel
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors
2022 StandoutNobel
Genetic Dissection of the Amyloid Precursor Protein in Developmental Function and Amyloid Pathogenesis
2010 StandoutNobel
Incorporation of sensing modalities into de novo designed fluorescence-activating proteins
2021 StandoutNobel
Biotin-transfer from a trifunctional crosslinker for identification of cell surface receptors of soluble protein ligands
2017
The role of liquid–liquid phase separation in aggregation of the TDP-43 low-complexity domain
2019 Standout
Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein
2014 Standout
The Active Conformation of β-Arrestin1
2007 StandoutNobel
Klotho suppresses RIG-I-mediated senescence-associated inflammation
2011
Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue
2010
Klotho Sensitivity of the Neuronal Excitatory Amino Acid Transporters EAAT3 and EAAT4
2013
Regulation of Renal Outer Medullary Potassium Channel and Renal K+ Excretion by Klotho
2009
Visual Arrestin Binding to Microtubules Involves a Distinct Conformational Change
2006
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Diastereospecific Photochemical Dimerization of a Stilbene‐Containing Daisy Chain Monomer in Solution as well as in the Solid State
2003 StandoutNobel
Imaging the Glycosylation State of Cell Surface Glycoproteins by Two‐Photon Fluorescence Lifetime Imaging Microscopy
2013 StandoutNobel
The ClusPro web server for protein–protein docking
2017 Standout
Klotho and Chronic Kidney Disease
2013
Functional Amyloid Formation within Mammalian Tissue
2005
Soluble serum Klotho levels in healthy subjects. Comparison of two different immunoassays
2013
Gelsolin amyloidosis: genetics, biochemistry, pathology and possible strategies for therapeutic intervention
2012
Klotho Deficiency Causes Vascular Calcification in Chronic Kidney Disease
2010 Standout
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
Protein aggregation and neurodegenerative disease
2004 Standout
Extracellular matrix structure
2015 Standout
Klotho
2009
Amyloid Protofilaments from the Calcium-binding Protein Equine Lysozyme: Formation of Ring and Linear Structures Depends on pH and Metal Ion Concentration
2003
Metalloendoprotease cleavage triggers gelsolin amyloidogenesis
2005
Protein folding and misfolding
2003 StandoutNature
The ADAM metalloproteinases
2008
The biofilm matrix
2010 Standout
Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses
2008
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention
2013 Standout
Simultaneous multi-lifetime multi-color STED imaging for colocalization analyses
2011 StandoutNobel
Regulation of Ion Channels by Secreted Klotho
2012
Furin at the cutting edge: From protein traffic to embryogenesis and disease
2002
We find them here, we find them there: Functional bacterial amyloid
2007
Improved Prediction of Signal Peptides: SignalP 3.0
2004 Standout
Myosin V Transports Secretory Vesicles via a Rab GTPase Cascade and Interaction with the Exocyst Complex
2011 StandoutNobel
Purification of active HOPS complex reveals its affinities for phosphoinositides and the SNARE Vam7p
2006
Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's disease
2008
Coming of age: ten years of next-generation sequencing technologies
2016 Standout
The SH3-like Domain Switches Its Interaction Partners to Modulate the Repression Activity of Mycobacterial Iron-dependent Transcription Regulator in Response to Metal Ion Fluctuations
2007
Differential Regulation of Lipoprotein and Hepatitis C Virus Secretion by Rab1b
2017 StandoutNobel
The Amyloid State of Proteins in Human Diseases
2012 Standout
A Pragmatic Guide to Enrichment Strategies for Mass Spectrometry–Based Glycoproteomics
2020 StandoutNobel
Endocrine functions of bone in mineral metabolism regulation
2008
FGF-23 and secondary hyperparathyroidism in chronic kidney disease
2013
The Pathobiology of Vascular Dementia
2013 Standout
Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry
2014 StandoutNobel
Therapeutic strategies for human amyloid diseases
2002
Design and implementation of bimolecular fluorescence complementation (BiFC) assays for the visualization of protein interactions in living cells
2006
Chronic Kidney Disease
2016 Standout
Membrane fusion
2008 StandoutNobel
Molecular Mechanisms of Amyloidosis
2003 Standout
Fibrillogenesis and Cytotoxic Activity of the Amyloid-forming Apomyoglobin Mutant W7FW14F
2004
Fibroblast Growth Factor 23 and Risks of Mortality and End-Stage Renal Disease in Patients With Chronic Kidney Disease
2011 Standout
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
2015 StandoutNobel
Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1
2008
Protein Misfolding, Functional Amyloid, and Human Disease
2006 Standout
Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis
2003
Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming
2009 StandoutNobel
Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF4)‐Derived Connective Hubs for Bioconjugation to DNA and Proteins
2019 StandoutNobel
Human serum leads to differentiation of human hepatoma cells, restoration of very-low-density lipoprotein secretion, and a 1000-fold increase in HCV Japanese fulminant hepatitis type 1 titers
2013 StandoutNobel
The Chemistry of Reactive Oxygen Species (ROS) Revisited: Outlining Their Role in Biological Macromolecules (DNA, Lipids and Proteins) and Induced Pathologies
2021 Standout
Secretion of amyloidogenic gelsolin progressively compromises protein homeostasis leading to the intracellular aggregation of proteins
2009
Bimolecular Fluorescence Complementation (BiFC) Analysis as a Probe of Protein Interactions in Living Cells
2008
The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
2011 Standout
Aerobic exercise training increases plasma Klotho levels and reduces arterial stiffness in postmenopausal women
2013
Intracellular Trafficking and Secretion of VLDL
2012
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Molecular Mechanisms and Genetics of Oxidative Stress in Alzheimer’s Disease
2019
Membrane Fusion: Grappling with SNARE and SM Proteins
2009 StandoutScienceNobel
Towards an Understanding of DNA Recognition by the Methyl-CpG Binding Domain 1
2005
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
Amyloid as a natural product
2003
APL-1, a Caenorhabditis elegans protein related to the human β-amyloid precursor protein, is essential for viability
2007
A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO2+” Donor of Unprecedented Reactivity, Selectivity, and Scope
2017 StandoutNobel
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
2016 StandoutNobel
Templated photochemical synthesis of a uracil vs. thymine receptor
2001
Works of Ci-Di Chen being referenced
Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17
2007
Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein
2008
The Neuroprotective Effect of Klotho is Mediated via Regulation of Members of the Redox System
2014
Visualization of APP dimerization and APP‐Notch2 heterodimerization in living cells using bimolecular fluorescence complementation
2006
Stage-Specific Assays to Study Biosynthetic Cargo Selection and Role of SNAREs in Export from the Endoplasmic Reticulum and Delivery to the Golgi
2000
Amyloid precursor protein interacts with notch receptors
2005
Furin initiates gelsolin familial amyloidosis in the Golgi through a defect in Ca2+ stabilization
2001
Methyl Groups of Thymine Bases Are Important for Nucleic Acid Recognition by DtxR,
2000
Small-Molecule Klotho Enhancers As Novel Treatment Of Neurodegeneration
2012