Citation Impact

Citing Papers

Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites
2009 StandoutScience
Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
2011 Standout
Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus
2009 StandoutNobel
Circulating microRNA profiles in human patients with acetaminophen hepatotoxicity or ischemic hepatitis
2014 StandoutNobel
Consistent blind protein structure generation from NMR chemical shift data
2008 StandoutNobel
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells
2008
Bats Are Natural Reservoirs of SARS-Like Coronaviruses
2005 StandoutScience
Pure Hemozoin Is Inflammatory In Vivo and Activates the NALP3 Inflammasome via Release of Uric Acid
2009
Cutting Edge: TNF-α Mediates Sensitization to ATP and Silica via the NLRP3 Inflammasome in the Absence of Microbial Stimulation
2009
Characterization of a CD44/CD122int Memory CD8 T Cell Subset Generated under Sterile Inflammatory Conditions
2009
P2X7 Receptor Differentially Couples to Distinct Release Pathways for IL-1β in Mouse Macrophage
2008
Identification of the Cellular Sensor That Stimulates the Inflammatory Response to Sterile Cell Death
2010
Hallmarks of Cancer: The Next Generation
2011 Standout
Emerging Role for Members of the Bcl-2 Family in Mitochondrial Morphogenesis
2009
Engagement of fatty acids with toll‐like receptor 2 drives interleukin‐1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal–induced gouty arthritis
2010
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
2009 StandoutNature
Uric Acid Is a Danger Signal Activating NALP3 Inflammasome in Lung Injury Inflammation and Fibrosis
2009
The Interleukin-1α Precursor is Biologically Active and is Likely a Key Alarmin in the IL-1 Family of Cytokines
2013
Hepatocyte Necrosis Induced by Oxidative Stress and IL-1α Release Mediate Carcinogen-Induced Compensatory Proliferation and Liver Tumorigenesis
2008
Necroptosis and its role in inflammation
2015 StandoutNature
Immunogenic cell death, DAMPs and anticancer therapeutics: An emerging amalgamation
2009
Virus Binding to a Plasma Membrane Receptor Triggers Interleukin-1α-Mediated Proinflammatory Macrophage Response In Vivo
2009
Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity
2011
Autoinflammatory Disease Reloaded: A Clinical Perspective
2010 Standout
Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome
2009
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
2012 StandoutNature
Towards an understanding of the adjuvant action of aluminium
2009
A role for mitochondria in NLRP3 inflammasome activation
2010 StandoutNature
Neutrophils in a mouse model of autoantibody‐mediated arthritis: Critical producers of Fc receptor γ, the receptor for C5a, and lymphocyte function−associated antigen 1
2010
Apoptosis: controlled demolition at the cellular level
2007 Standout
Innate apoptotic immunity: the calming touch of death
2008
The interleukin‐1 receptor/Toll‐like receptor superfamily: 10 years of progress
2008
Phylogenomics and bioinformatics of SARS-CoV
2004
Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity
2011
Developments in the scientific and clinical understanding of gout
2008
Pattern Recognition Receptors and Inflammation
2010 Standout
Prospective Evaluation of a Shortened Regimen of Treatment for Acute Osteomyelitis and Septic Arthritis in Children
2009
TLR-2 and TLR-9 are sensors of apoptosis in a mouse model of doxorubicin-induced acute inflammation
2011
TLR-dependent T cell activation in autoimmunity
2011
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
2009 StandoutNature
Conditional Deletion of IκB-Kinase-β Accelerates Helicobacter-Dependent Gastric Apoptosis, Proliferation, and Preneoplasia
2009
Gout
2009 Standout
The inflammasome, autoinflammatory diseases, and gout
2007
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Recent developments in crystal-induced inflammation pathogenesis and management
2007
Taming cancer by inducing immunity via dendritic cells
2007
How dying cells alert the immune system to danger
2008
The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis
2009 Standout
Immunity, Inflammation, and Cancer
2010 Standout
IL‐1, IL‐18, and IL‐33 families of cytokines
2008
A calculated response: control of inflammation by the innate immune system
2008
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
2013 StandoutNature
Non-canonical inflammasome activation targets caspase-11
2011 StandoutNature
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
2008 Nature
Interleukin-33 – cytokine of dual function or novel alarmin?
2009
Coronavirus Genome Structure and Replication
2005
Origin and physiological roles of inflammation
2008 StandoutNature
Sterile inflammation: sensing and reacting to damage
2010 Standout
Coronavirus Pathogenesis
2011
Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells
2009 StandoutNature
The Inflammasomes
2010 Standout
TOLL-LIKE RECEPTORS IN ISCHEMIA-REPERFUSION INJURY
2009
Function of Nod‐like receptors in microbial recognition and host defense
2008
Progress and challenges in translating the biology of atherosclerosis
2011 StandoutNature
Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
2012
Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
2011 StandoutNobel
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Caspase 1–independent activation of interleukin‐1β in neutrophil‐predominant inflammation
2009
Necrosis: C-Type Lectins Sense Cell Death
2009
Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation
2006
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
2010 StandoutNature
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Exploring the full spectrum of macrophage activation
2008 Standout
Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability
2009 Standout
Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation
2011
Inflammasomes in health and disease
2012 StandoutNature
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
IL‐1: Discoveries, controversies and future directions
2010
Basic Calcium Phosphate Crystals Induce Monocyte/Macrophage IL-1β Secretion through the NLRP3 Inflammasome In Vitro
2011
Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management
2015 Standout
Horror Autoinflammaticus: The Molecular Pathophysiology of Autoinflammatory Disease
2009
Cutting Edge: Critical Role for Mesothelial Cells in Necrosis-Induced Inflammation through the Recognition of IL-1α Released from Dying Cells
2008
The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1
2009
IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice
2007
Overview of the IL‐1 family in innate inflammation and acquired immunity
2017
Differential release of chromatin-bound IL-1α discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation
2010
Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells
2010 StandoutNobel
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
2011 StandoutNobel
Mitochondrial Fission, Fusion, and Stress
2012 StandoutScience
Immunological and Inflammatory Functions of the Interleukin-1 Family
2009 Standout
Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
2009
Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease
2020 Standout
The Inflammasomes: Guardians of the Body
2009 Standout
Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation
2011
The Inflammatory Response to Cell Death
2008
Regulation of Adaptive Immunity by the Innate Immune System
2010 StandoutScience
Endogenous Oils Derived From Human Adipocytes Are Potent Adjuvants That Promote IL-1α–Dependent Inflammation
2014
A Novel Coronavirus from Patients with Pneumonia in China, 2019
2020 Standout
NK cell–mediated killing of target cells triggers robust antigen-specific T cell–mediated and humoral responses
2009 StandoutNobel
Coronavirus Pathogenesis and the Emerging Pathogen Severe Acute Respiratory Syndrome Coronavirus
2005
Cyclophilin A Is a Damage-Associated Molecular Pattern Molecule That Mediates Acetaminophen-Induced Liver Injury
2011
High Mobility Group Box 1 Protein Binding to Lipopolysaccharide Facilitates Transfer of Lipopolysaccharide to CD14 and Enhances Lipopolysaccharide-Mediated TNF-α Production in Human Monocytes
2008
Novel β-Barrel Fold in the Nuclear Magnetic Resonance Structure of the Replicase Nonstructural Protein 1 from the Severe Acute Respiratory Syndrome Coronavirus
2007 Nobel
Innate or Adaptive Immunity? The Example of Natural Killer Cells
2011 StandoutScience
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel

Works of Chun‐Jen Chen being referenced

Identification of a key pathway required for the sterile inflammatory response triggered by dying cells
2007
Uric acid promotes an acute inflammatory response to sterile cell death in mice
2010
MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals
2006
Natural endogenous adjuvants
2004
Induction of Apoptosis in Murine Coronavirus-Infected Cultured Cells and Demonstration of E Protein as an Apoptosis Inducer
1999
Characteristics and outcome of septic arthritis in children.
2006
Murine Coronavirus Replication Induces Cell Cycle Arrest in G0/G1Phase
2004
Murine Coronavirus Nonstructural Protein p28 Arrests Cell Cycle in G0/G1Phase
2004
Nucleocapsid-Independent Specific Viral RNA Packaging via Viral Envelope Protein and Viral RNA Signal
2003
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