Standout Papers

Control of Regulatory T Cells by Co-signal Molecules 2017 2026 2020 2023 671
  1. Control of Regulatory T Cells by Co-signal Molecules (2019)
    James B. Wing, Christopher Tay et al. Advances in experimental medicine and biology
  2. Hyper-Progressive Disease: The Potential Role and Consequences of T-Regulatory Cells Foiling Anti-PD-1 Cancer Immunotherapy (2020)
    Christopher Tay, Shimon Sakaguchi et al. Cancers
  3. A distinct subpopulation of CD25T-follicular regulatory cells localizes in the germinal centers (2017)
    James B. Wing, Yohko Kitagawa et al. Proceedings of the National Academy of Sciences
  4. Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy (2023)
    Christopher Tay, Atsushi Tanaka et al. Cancer Cell
  5. PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer (2019)
    Takahiro Kamada, Yosuke Togashi et al. Proceedings of the National Academy of Sciences

Citation Impact

Citing Papers

A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients
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Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis
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A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity
2023 StandoutNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Reading the glyco-code: New approaches to studying protein–carbohydrate interactions
2022 StandoutNobel
Head and neck squamous cell carcinoma
2020 Standout
Regulatory T cells in tumor microenvironment: new mechanisms, potential therapeutic strategies and future prospects
2020
The role of B cells in atherosclerosis
2018
Synovial Tissue Inflammation Mediated by Autoimmune T Cells
2019 StandoutNobel
Chronic inflammation in the etiology of disease across the life span
2019 Standout
Adaptive immunity in atherogenesis: new insights and therapeutic approaches
2013
Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy
2021
Cellular senescence in aging and age-related disease: from mechanisms to therapy
2015 Standout
Hallmarks of aging: An expanding universe
2023 Standout
Microglial cell origin and phenotypes in health and disease
2011 Standout
The changing landscape of atherosclerosis
2021 StandoutNature
Atherosclerosis: current pathogenesis and therapeutic options
2011 Standout
Anti-angiogenic agents — overcoming tumour endothelial cell anergy and improving immunotherapy outcomes
2021
Control of Germinal Center Responses by T-Follicular Regulatory Cells
2018 StandoutNobel
T Follicular Helper Cell Biology: A Decade of Discovery and Diseases
2019
CXCR3 expression in regulatory T cells drives interactions with type I dendritic cells in tumors to restrict CD8+ T cell antitumor immunity
2023
Macrophages in atherosclerosis: a dynamic balance
2013 Standout
IL-6 as a keystone cytokine in health and disease
2015 Standout
ALDH4A1 is an atherosclerosis auto-antigen targeted by protective antibodies
2020 Nature
Gut microbiome and health: mechanistic insights
2022 Standout
Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4
2019
The role of T cells in age-related diseases
2021
Macrophages in Tissue Repair, Regeneration, and Fibrosis
2016 Standout
The immune system in atherosclerosis
2011 Standout
Immune Effector Mechanisms Implicated in Atherosclerosis: From Mice to Humans
2013
The immunology of atherosclerosis
2017
Neutrophil extracellular traps in immunity and disease
2017 Standout
The innate immune response to products of phospholipid peroxidation
2012
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
2023 Standout
Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals
2020 Standout
B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction
2013
Atherosclerosis
2019 Standout
Targeting ferroptosis as a vulnerability in cancer
2022 Standout
Atherosclerosis and the role of immune cells
2015
PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment
2022 StandoutNobel
Dynamics of effector and naïve Regulatory T cells throughout pregnancy
2020 StandoutNobel
Neutrophils in cancer: neutral no more
2016 Standout
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Microbial modulation of cardiovascular disease
2018
Regulatory T Cell-Specific Epigenomic Region Variants Are a Key Determinant of Susceptibility to Common Autoimmune Diseases
2020 StandoutNobel
New Treg cell-based therapies of autoimmune diseases: towards antigen-specific immune suppression
2020 StandoutNobel
Inflammasomes: mechanism of action, role in disease, and therapeutics
2015 Standout
Opportunities for Treg cell therapy for the treatment of human disease
2023 StandoutNobel
Imbalanced gp130 signalling in ApoE-deficient mice protects against atherosclerosis
2014
Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
2018 Standout
A guide to cancer immunotherapy: from T cell basic science to clinical practice
2020 Standout
Thrombosis as an intravascular effector of innate immunity
2012 Standout
Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer
2019 StandoutNobel
Overcoming microenvironmental resistance to PD-1 blockade in genetically engineered lung cancer models
2021
Regulatory T Cells and Human Disease
2020 StandoutNobel
Targeting Treg cells in cancer immunotherapy
2019 StandoutNobel
Adaptive Response of T and B Cells in Atherosclerosis
2016
Inflammation in Atherosclerosis
2012 Standout
Strain-Specific Manifestation of Lupus-like Systemic Autoimmunity Caused by Zap70 Mutation
2019 StandoutNobel
Extramedullary Hematopoiesis Generates Ly-6C high Monocytes That Infiltrate Atherosclerotic Lesions
2011
Control of foreign Ag‐specific Ab responses by Treg and Tfr
2020 StandoutNobel
The Biological Basis for Cardiac Repair After Myocardial Infarction
2016 Standout
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
2014 Standout
B cell–intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice
2021 StandoutNobel
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
Rapid progression of adult T-cell leukemia/lymphoma as tumor-infiltrating Tregs after PD-1 blockade
2019
Regulatory roles of IL-10–producing human follicular T cells
2019 StandoutNobel
Tumor-associated macrophages promote intratumoral conversion of conventional CD4 + T cells into regulatory T cells via PD-1 signalling
2022
Leukocytes Link Local and Systemic Inflammation in Ischemic Cardiovascular Disease
2016
Impaired T cell receptor signaling and development of T cell–mediated autoimmune arthritis
2020 StandoutNobel
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody
2018 StandoutNobel

Works of Christopher Tay being referenced

PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Phosphatidylserine liposomes mimic apoptotic cells to attenuate atherosclerosis by expanding polyreactive IgM producing B1a lymphocytes
2015
Depletion of B2 but Not B1a B Cells in BAFF Receptor-Deficient ApoE−/− Mice Attenuates Atherosclerosis by Potently Ameliorating Arterial Inflammation
2012
BAFF Receptor mAb Treatment Ameliorates Development and Progression of Atherosclerosis in Hyperlipidemic ApoE−/− Mice
2013
B-cell-specific depletion of tumour necrosis factor alpha inhibits atherosclerosis development and plaque vulnerability to rupture by reducing cell death and inflammation
2016
Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy
2023 StandoutNobel
Follicular B Cells Promote Atherosclerosis via T Cell–Mediated Differentiation Into Plasma Cells and Secreting Pathogenic Immunoglobulin G
2018
Cytotoxic and Proinflammatory CD8 + T Lymphocytes Promote Development of Vulnerable Atherosclerotic Plaques in ApoE-Deficient Mice
2013
Conventional B2 B Cell Depletion Ameliorates whereas Its Adoptive Transfer Aggravates Atherosclerosis
2010
B1a B Lymphocytes Are Atheroprotective by Secreting Natural IgM That Increases IgM Deposits and Reduces Necrotic Cores in Atherosclerotic Lesions
2011
Protective Role for Toll-Like Receptor-9 in the Development of Atherosclerosis in Apolipoprotein E–Deficient Mice
2014
A distinct subpopulation of CD25T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
Rankless by CCL
2026