Citation Impact
Citing Papers
Signal transduction and regulation in smooth muscle
1994 StandoutNature
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors
2022 StandoutNobel
Peptide-binding specificity of the molecular chaperone BiP
1991 StandoutNatureNobel
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
1995 StandoutNobel
Human Neutrophil Granule Cationic Protein CAP37 is a Specific Macrophage Chemotaxin that Shares Homology with Inflammatory Proteinases
1991
Expression of human proteoglycan in Chinese hamster ovary cells inhibits cell proliferation
1988 Nature
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE
1994 StandoutNature
Identification of Elastase as a Secretory Protease from Cultured Rat Microglia
1992
Species differences in platelet responses to thrombin and SFLLRN. Receptor-mediated calcium mobilization and aggregation, and regulation by protein kinases
1995
Tertiary structure of Bacillus thermoproteolyticus [4Fe-4S] ferredoxin
1988
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
Beyond Cholesterol
1989 Standout
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
1995 StandoutNature
Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line.
1992
Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction
1992 StandoutNature
Protease‐activated receptors in hemostasis, thrombosis and vascular biology
2005
Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin
1999
Production of Platelet-Derived Growth Factor–like Mitogen by Smooth-Muscle Cells from Human Atheroma
1988
Thrombin signalling and protease-activated receptors
2000 StandoutNature
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
1998 StandoutNature
Protease-activated receptor 3 is a second thrombin receptor in humans
1997 Nature
Mast cell tryptases and chymases in inflammation and host defense
2007
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
Regulation of angiogenesis by hypoxia: role of the HIF system
2003 StandoutNobel
The development of allergic inflammation
2008 StandoutNature
Inflammatory Mediators, Cytokines, and Adhesion Molecules in Pulmonary Inflammation and Injury
1996
The microenvironment of the tumour–host interface
2001 StandoutNature
Negative regulation of transforming growth factor-β by the proteoglycan decorin
1990 StandoutNature
Autocrine-paracrine mechanisms of vascular myocytes in systemic hypertension
1987
Mast Cell Proteases
2007
P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury
2003 StandoutNature
Amino acid sequence of CAP37, a human neutrophil granule‐derived antibacterial and monocyte‐specific chemotactic glycoprotein structurally similar to neutrophil elastase
1990
Structure of [4Fe-4S] ferredoxin from Bacillus thermoproteolyticus refined at 2.3 Å resolution
1989
Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
1994 StandoutNature
A dual thrombin receptor system for platelet activation
1998 Nature
Male–female differences in fertility and blood pressure in ACE-deficient mice
1995 StandoutNatureNobel
Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo
1992 Nature
The PPARα–leukotriene B4 pathway to inflammation control
1996 Nature
Atherosclerosis — An Inflammatory Disease
1999 Standout
Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo. Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-alpha, and transforming growth factor-beta.
1991
Physiology of Local Renin-Angiotensin Systems
2006 Standout
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
1995 StandoutNobel
Regulation of vascular smooth muscle cell integrin expression by transforming growth factor β1 and by platelet‐derived growth factor‐BB
1992
.alpha.-Macroglobulin from Limulus polyphemus exhibits proteinase inhibitory activity and participates in a hemolytic system
1990
Points of control in inflammation
2002 StandoutNature
Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins
1991
Inflammation, Atherosclerosis, and Coronary Artery Disease
2005 Standout
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
2005 StandoutNature
Inflammation, Aspirin, and the Risk of Cardiovascular Disease in Apparently Healthy Men
1997 Standout
Elastin is an essential determinant of arterial morphogenesis
1998 StandoutNature
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry
2014 StandoutNobel
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
Chronic thromboembolic pulmonary hypertension
2014
Granzymes, a Family of Serine Proteases Released from Granules of Cytolytic T Lymphocytes upon T Cell Receptor Stimulation
1988
The multiple roles of tumour stroma
1997
NAD(P)H Oxidase-Derived Reactive Oxygen Species as Mediators of Angiotensin II Signaling
2002
Granulocyte-angiotensin system. Identification of angiotensinogen as the plasma protein substrate of leukocyte cathepsin G
1984
How the protease thrombin talks to cells
1999
Cathepsin G is a strong platelet agonist released by neutrophils
1988
Sol Sherry Lecture in Thrombosis
1998
Leukocyte lipid body formation and eicosanoid generation: cyclooxygenase-independent inhibition by aspirin.
1996 StandoutNobel
Heparin protects basic and acidic FGF from inactivation
1986
Introduction of interleukin-3 gene into stromal cells from the bone marrow alters hemopoietic differentiation but does not modify stem cell renewal
1988
Intracellular targeting and trafficking of thrombin receptors. A novel mechanism for resensitization of a G protein-coupled receptor.
1994 StandoutNobel
Abnormal Vascular Function and Hypertension in Mice Deficient in Estrogen Receptor β
2002 StandoutScienceNobel
Fibronectin stimulates macrophage uptake of low density lipoprotein-heparin-collagen complexes.
1988
Genetically increased angiotensin I-converting enzyme level and renal complications in the diabetic mouse
2001 StandoutNobel
Antibody to Thrombin Receptor Inhibits Neointimal Smooth Muscle Cell Accumulation Without Causing Inhibition of Platelet Aggregation or Altering Hemostatic Parameters After Angioplasty in Rat
1998
Targeting G βγ signaling in arterial vascular smooth muscle proliferation: A novel strategy to limit restenosis
1999 StandoutNobel
Altered Vascular Injury Responses in Mice Deficient in Protease-Activated Receptor-1
1999
Angiotensinogen gene is expressed and differentially regulated in multiple tissues of the rat.
1986
Angiotensin I converting enzyme and the changes in our concepts through the years. Lewis K. Dahl memorial lecture.
1990
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Regulation of differentiated properties and proliferation of arterial smooth muscle cells.
1990
Human Plasminogen Activator Inhibitor-1 (PAI-1) Deficiency: Characterization of a Large Kindred With a Null Mutation in the PAI-1 Gene
1997
Role of Prostacyclin in the Cardiovascular Response to Thromboxane A 2
2002 StandoutScience
Chronic Thromboembolic Pulmonary Hypertension
2006 Standout
Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology
1988 StandoutScience
Transforming growth factor-beta activity is potentiated by heparin via dissociation of the transforming growth factor-beta/alpha 2-macroglobulin inactive complex.
1989
Angiogenic Factors
1987 StandoutScience
Protein Control of Redox Potentials of Iron−Sulfur Proteins
1996 StandoutNobel
Specificity and reactivity of human leukocyte elastase, porcine pancreatic elastase, human granulocyte cathepsin G, and bovine pancreatic chymotrypsin with arylsulfonyl fluorides. Discovery of a new series of potent and specific irreversible elastase inhibitors.
1982
Signaling Mechanisms Underlying the Vascular Myogenic Response
1999
Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors
1985
Induction of the Plasminogen Activator Inhibitor-1 Gene Expression by Mild Hypoxia Via a Hypoxia Response Element Binding the Hypoxia-Inducible Factor-1 in Rat Hepatocytes
1999
A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association.
1994
Constitutive expression of a complement-like protein in Toll and JAK gain-of-function mutants ofDrosophila
2000 StandoutNobel
The Pathogenesis of Atherosclerosis: Atherogenesis and Inflammation
1989
Requirement of Vascular Integrin α v β 3 for Angiogenesis
1994 StandoutScience
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
2001 StandoutNobel
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease
2002 Standout
G protein coupling to the thrombin receptor in Chinese hamster lung fibroblasts.
1994
The Intima
1995
Mechanisms and Genes of Cellular Suicide
1995 StandoutScience
Cloning of the gene and cDNA for human heart chymase.
1991
Works of Christopher Reilly being referenced
An antiproliferative heparan sulfate species produced by postconfluent smooth muscle cells.
1985
Thrombin Receptor Agonist Peptide Induction of Mitogenesis in CCL39 Cells
1993
Heparin‐like molecules regulate the number of epidermal growth factor receptors on vascular smooth muscle cells
1988
Rat vascular smooth muscle cells immortalized with SV40 large T antigen possess defined smooth muscle cell characteristics including growth inhibition by heparin
1990
Atherogenic Regulation by Heparin‐like Moleculesa
1985
Effects of Subtype-Selective and Balanced Angiotensin II Receptor Antagonists in a Porcine Coronary Artery Model of Vascular Restenosis
1996
Platelet-derived growth factor and transforming growth factor-beta regulate plasminogen activator inhibitor-1 synthesis in vascular smooth muscle cells
1991
Human Leucocyte Elastase and Cathepsin G: Structural and Functional Characteristics
1980
Heparin inhibition of smooth muscle cell proliferation: A cellular site of action
1986
Soluble Cell Adhesion Molecules in Hypertriglyceridemia and Potential Significance on Monocyte Adhesion
1998
The degradation of human lung elastin by neutrophil proteinases
1980
Rapid conversion of angiotensin I to angiotensin II by neutrophil and mast cell proteinases.
1982
Antiproliferative effects of heparin on vascular smooth muscle cells are reversed by epidermal growth factor
1987
Species Variability in Platelet and other Cellular Responsiveness to Thrombin Receptor-derived Peptides
1994
Inactivation of bradykinin and kallidin by cathepsin G and mast cell chymase
1985
Human leukocyte cathepsin G. Subsite mapping with 4-nitroanilides, chemical modification, and effect of possible cofactors
1985
Heparin Prevents Vascular Smooth Muscle Cell Progression through the G1 Phase of the Cell Cycle
1989
Development and validation of an alternative dermal sensitization test: The mouse ear swelling test (MEST)
1986
Suppression of thrombolysis in a canine model of pulmonary embolism.
1994
Complete amino acid sequence of the 4Fe-4S, thermostable ferredoxin from Clostridium thermoaceticum
1982
Molecular cloning of human cathepsin G: structural similarity to mast cell and cytotoxic T lymphocyte proteinases
1987
Both circulating and clot-bound plasminogen activator inhibitor-1 inhibit endogenous fibrinolysis in the rat.
1991