Citation Impact
Citing Papers
Genetic-related and carbohydrate-related factors affecting liver fat accumulation
2012
Lipolysis – A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores
2010
Genetic determinants of hepatic steatosis in man
2011
Homozygosity for the patatin‐like phospholipase‐3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease†
2010
Potential risks associated with increased plasma plant-sterol levels
2014
FAT SIGNALS - Lipases and Lipolysis in Lipid Metabolism and Signaling
2012
Biochemistry and pathophysiology of intravascular and intracellular lipolysis
2013
Non-alcoholic fatty liver disease – A global public health perspective
2018 Standout
Genetic Predisposition in NAFLD and NASH: Impact on Severity of Liver Disease and Response to Treatment
2013
Genetic modifiers of non-alcoholic fatty liver disease progression
2011
Mechanisms of hepatic stellate cell activation
2017 Standout
The role of lipid droplets in metabolic disease in rodents and humans
2011
The Effect of PNPLA3 on Fibrosis Progression and Development of Hepatocellular Carcinoma: A Meta-analysis
2014
PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals
2012
The perilipin family of lipid droplet proteins: Gatekeepers of intracellular lipolysis
2017 Standout
Hepatic Fat Accumulation Is Modulated by the Interaction between the rs738409 Variant in the PNPLA3 Gene and the Dietary Omega6/Omega3 PUFA Intake
2012
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
2012 StandoutNature
Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention
2017 Standout
Mouse patatin-like phospholipase domain-containing 3 influences systemic lipid and glucose homeostasis
2011
Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome
2010
Fibrosis and Adipose Tissue Dysfunction
2013 Standout
Dissociating fatty liver and diabetes
2012
Evolution of Inflammation in Nonalcoholic Fatty Liver Disease: The Multiple Parallel Hits Hypothesis
2010 Standout
Common polymorphism in the PNPLA3/adiponutrin gene confers higher risk of cirrhosis and liver damage in alcoholic liver disease
2011
Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation
2017
Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance
2011
NAFLD and diabetes mellitus
2016
Unravelling the pathogenesis of fatty liver disease: patatin-like phospholipase domain-containing 3 protein
2010
Statin use and non-alcoholic steatohepatitis in at risk individuals
2015
Genetic predisposition in nonalcoholic fatty liver disease
2017
The PNPLA3 I148M polymorphism is associated with insulin resistance and nonalcoholic fatty liver disease in a normoglycaemic population
2011
A 360-degree overview of paediatric NAFLD: Recent insights
2012
Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice
2010
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)
2016 Standout
Patatin-Like Phospholipase Domain-Containing 3/Adiponutrin Deficiency in Mice Is Not Associated with Fatty Liver Disease†,‡
2010
Effect of short-term carbohydrate overfeeding and long-term weight loss on liver fat in overweight humans
2012
Hepatocellular carcinoma in nonalcoholic fatty liver: Role of environmental and genetic factors
2014
The Association of Genetic Variability in Patatin-Like Phospholipase Domain-Containing Protein 3 (PNPLA3) with Histological Severity of Nonalcoholic Fatty Liver Disease†
2010
Non-alcoholic fatty liver disease
2021 Standout
Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association
2021 Standout
Lack of Exercise Is a Major Cause of Chronic Diseases
2012 Standout
The genetics of NAFLD
2013
Systematic review: the epidemiology and natural history of non‐alcoholic fatty liver disease and non‐alcoholic steatohepatitis in adults
2011 Standout
Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease
2011
Dynamics and functions of lipid droplets
2018 Standout
The Riddle of Nonalcoholic Fatty Liver Disease: Progression From Nonalcoholic Fatty Liver to Nonalcoholic Steatohepatitis
2015
Distinct regulation of adiponutrin/PNPLA3 gene expression by the transcription factors ChREBP and SREBP1c in mouse and human hepatocytes
2010
Characterization of European Ancestry Nonalcoholic Fatty Liver Disease-Associated Variants in Individuals of African And Hispanic Descent
2013
Genetic Factors That Affect Risk of Alcoholic and Nonalcoholic Fatty Liver Disease
2016
Variant in the glucokinase regulatory protein ( GCKR ) gene is associated with fatty liver in obese children and adolescents
2011
PPARγ signaling and metabolism: the good, the bad and the future
2013 Standout
Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol
2011
Animal models of nonalcoholic fatty liver disease
2010
A Common Variant in the Patatin-Like Phospholipase 3 Gene ( PNPLA3 ) Is Associated with Fatty Liver Disease in Obese Children and Adolescents
2010
The global NAFLD epidemic
2013 Standout
Toward Genetic Prediction of Nonalcoholic Fatty Liver Disease Trajectories: PNPLA3 and Beyond
2020
What We Talk About When We Talk About Fat
2014 Standout
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
Nonalcoholic fatty liver disease
2010
Lipid-induced insulin resistance: unravelling the mechanism
2010
Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets
2011 Standout
Type 2 diabetes mellitus
2015 Standout
Ethnopharmacological uses, phytochemistry, biological activities, and therapeutic applications of Clinacanthus nutans (Burm. f.) Lindau: A comprehensive review
2017 Standout
Energy Metabolism in the Liver
2014 Standout
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Past, present and future perspectives in nonalcoholic fatty liver disease
2019
Nonalcoholic Fatty Liver Disease, Hepatic Insulin Resistance, and Type 2 Diabetes
2013
PNPLA3 Variants Specifically Confer Increased Risk for Histologic Nonalcoholic Fatty Liver Disease But Not Metabolic Disease†,‡
2010
NAFLD: A multisystem disease
2015 Standout
Genetic Polymorphisms of the Human PNPLA3 Gene Are Strongly Associated with Severity of Non-Alcoholic Fatty Liver Disease in Japanese
2012
DAG tales: the multiple faces of diacylglycerol—stereochemistry, metabolism, and signaling
2015
Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro
2012
Liver triacylglycerol lipases
2011
AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease
2023 Standout
The Genetics of Nonalcoholic Fatty Liver Disease: Spotlight on PNPLA3 and TM6SF2
2015
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Non-Alcoholic Fatty Liver Disease: Metabolic, Genetic, Epigenetic and Environmental Risk Factors
2021
Nonalcoholic Fatty Liver Disease: Pathogenesis and Disease Spectrum
2016
A feed-forward loop amplifies nutritional regulation of PNPLA3
2010
The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases
2017 Standout
Impact of the Association Between PNPLA3 Genetic Variation and Dietary Intake on the Risk of Significant Fibrosis in Patients With NAFLD
2020
Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity
2016 Standout
Pathophysiology of Type 2 Diabetes Mellitus
2020 Standout
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
2016 Standout
The rs2294918 E434K variant modulates patatin‐like phospholipase domain‐containing 3 expression and liver damage
2015
The global epidemiology of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH): a systematic review
2023 Standout
Human Fatty Liver Disease: Old Questions and New Insights
2011 StandoutScience
EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma
2018 Standout
The Controversial Role of Human Gut Lachnospiraceae
2020 Standout
PNPLA3, CGI‐58, and Inhibition of Hepatic Triglyceride Hydrolysis in Mice
2019
Review article: the emerging role of genetics in precision medicine for patients with non‐alcoholic steatohepatitis
2020
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
2016 Standout
Silymarin/Silybin and Chronic Liver Disease: A Marriage of Many Years
2017 Standout
The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation
2017
Nonalcoholic Fatty Liver Disease
2015 Standout
Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis
2014
Works of Christopher McPhaul being referenced
A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis
2009
Phytosterols differentially influence ABC transporter expression, cholesterol efflux and inflammatory cytokine secretion in macrophage foam cells
2010