Citation Impact
Citing Papers
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Snail1-Dependent Activation of Cancer-Associated Fibroblast Controls Epithelial Tumor Cell Invasion and Metastasis
2016
High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells
2005 StandoutScience
Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix
2006 Standout
Fate-determining mechanisms in epithelial–myofibroblast transition: major inhibitory role for Smad3
2010
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Synaptotagmins form a hierarchy of exocytotic Ca 2+ sensors with distinct Ca 2+ affinities
2002 StandoutNobel
Alternative Activation Is an Innate Response to Injury That Requires CD4+ T Cells to be Sustained during Chronic Infection
2007 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
TGF-β inhibition enhances chemotherapy action against triple-negative breast cancer
2013
Transition from inflammation to proliferation: a critical step during wound healing
2016 Standout
Synaptotagmin III/VII Isoforms Mediate Ca2+-induced Insulin Secretion in Pancreatic Islet β-Cells
2000
Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
2003
Inflammation and metabolic disorders
2006 StandoutNature
A Self-Enabling TGFβ Response Coupled to Stress Signaling
2003
Cellular and molecular mechanisms of fibrosis
2007 Standout
Cancer nanomedicine: progress, challenges and opportunities
2016 Standout
Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus
2003 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Group VIA Phospholipase A2 Forms a Signaling Complex with the Calcium/Calmodulin-dependent Protein Kinase IIβ Expressed in Pancreatic Islet β-Cells
2004
Wound repair and regeneration
2008 StandoutNature
Pulmonary fibrosis: pathogenesis, etiology and regulation
2009 Standout
Increased Bleomycin-Induced Skin Fibrosis in Mice Lacking the Th1-Specific Transcription Factor T-bet
2006
Lymphangiogenesis: Molecular Mechanisms and Future Promise
2010 Standout
TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation
2009 Standout
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
2015 StandoutNature
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors
2006
Regulation and role of transforming growth factor-β in immune tolerance induction and inflammation
2004
TGFβ: the molecular Jekyll and Hyde of cancer
2006
Complementation of reduced survival, hypotension, and renal abnormalities in angiotensinogen-deficient mice by the human renin and human angiotensinogen genes.
1997 StandoutNobel
Scleroderma
2009 Standout
Essential Roles for Early Growth Response Transcription Factor Egr-1 in Tissue Fibrosis and Wound Healing
2009
Nonresolving Inflammation
2010 Standout
Inhibition of TGFβ signaling in cancer therapy
2005
Characterization of an ATP-stimulatable calcium2+ independent phospholipase A2 from clonal insulin-secreting HIT cells and rat pancreatic islets: a possible molecular component of the .beta.-cell fuel sensor
1994
Combination delivery of TGF-β inhibitor and IL-2 by nanoscale liposomal polymeric gels enhances tumour immunotherapy
2012
Fibrotic disease and the TH1/TH2 paradigm
2004 Standout
TGF-β1is a negative regulator of lymphatic regeneration during wound repair
2008
Mediators of Chronic Obstructive Pulmonary Disease
2004
Functional Significance of Smad2 in Regulating Basal Keratinocyte Migration During Wound Healing
2005
Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy
2013 Standout
Topical Application of a Peptide Inhibitor of Transforming Growth Factor-β1 Ameliorates Bleomycin-Induced Skin Fibrosis
2005
EMT: 2016
2016 Standout
TGFβ in Cancer
2008 Standout
The role of connective tissue growth factor, a multifunctional matricellular protein, in fibroblast biology
2003
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
2013 StandoutNobel
Cancer immunotherapy comes of age
2011 StandoutNature
Smad3 is key to TGF-β-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis
2005
Transient adenoviral gene transfer of Smad7 prevents injury-induced epithelial–mesenchymal transition of lens epithelium in mice
2004
Origin and physiological roles of inflammation
2008 StandoutNature
Smad3: A Key Player in Pathogenetic Mechanisms Dependent on TGF‐β
2003
Western Diet Modulates Insulin Signaling, c-Jun N-Terminal Kinase Activity, and Insulin Receptor Substrate-1ser307 Phosphorylation in a Tissue-Specific Fashion
2005
TGF-β Tumor Suppression through a Lethal EMT
2016
TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology
2016 Standout
The basics of epithelial-mesenchymal transition
2009 Standout
Clonal evolution in cancer
2012 StandoutNature
Synthesis and biological evaluation of 2-pyridyl-substituted pyrazoles and imidazoles as transforming growth factor-β type 1 receptor kinase inhibitors
2010
Function and Inhibition of Intracellular Calcium-independent Phospholipase A2
1997
Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS
2005 StandoutNobel
Targeting the TGFβ, endothelin-1 and CCN2 axis to combat fibrosis in scleroderma
2008
Release of sphingosine‐1‐phosphate from human platelets is dependent on thromboxane formation
2011
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Heat shock proteins in fibrosis and wound healing: Good or evil?
2014
Bromoenol Lactone Inhibits Magnesium-dependent Phosphatidate Phosphohydrolase and Blocks Triacylglycerol Biosynthesis in Mouse P388D1 Macrophages
1996
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Radiation and the microenvironment – tumorigenesis and therapy
2005
Pancreatic cancer–associated retinoblastoma 1 dysfunction enables TGF-β to promote proliferation
2013
TGF‐β signaling and the fibrotic response
2004 Standout
Cell-Type-Specific Activation of PAK2 by Transforming Growth Factor β Independent of Smad2 and Smad3
2003
Advances in skin grafting and treatment of cutaneous wounds
2014 StandoutScience
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
2015 StandoutNobel
Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
2003
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
2008 StandoutNobel
Transcriptional Control of Wound Repair
2007
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Dendritic cells are specialized accessory cells along with TGF-β for the differentiation of Foxp3+ CD4+ regulatory T cells from peripheral Foxp3− precursors
2007 StandoutNobel
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Angiotensin II stimulates the release of phospholipid-derived second messengers through multiple receptor subtypes in heart cells.
1994
IL-13 Activates a Mechanism of Tissue Fibrosis That Is Completely TGF-β Independent
2004
Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS
2005 StandoutNobel
Smad3 Null Mice Develop Airspace Enlargement and Are Resistant to TGF-β-Mediated Pulmonary Fibrosis
2004
Growth differentiation factor 9:bone morphogenetic protein 15 heterodimers are potent regulators of ovarian functions
2013
Signal Transduction Pathway through Activin Receptors as a Therapeutic Target of Musculoskeletal Diseases and Cancer
2008
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis
2008 Standout
From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles
2011 Standout
Wound-Healing Studies in Transgenic and Knockout Mice
2004
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Inflammation and metabolism in tissue repair and regeneration
2017 StandoutScience
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Regulation of Wound Healing by Growth Factors and Cytokines
2003 Standout
Works of Christopher Major being referenced
Mice Lacking Smad3 Are Protected Against Cutaneous Injury Induced by Ionizing Radiation
2002
Fuel secretagogue stimulation of arachidonic acid accumulation in fresh and cultured pancreatic islets
1993
Interference with Transforming Growth Factor-β/ Smad3 Signaling Results in Accelerated Healing of Wounds in Previously Irradiated Skin
2003
Diacylglycerol Hydrolysis to Arachidonic Acid Is Necessary for Insulin Secretion from Isolated Pancreatic Islets: Sequential Actions of Diacylglycerol and Monoacylglycerol Lipases
1994
Inhibition of phospholipase A2 and insulin secretion in pancreatic islets
1992
Transient activation of calcium-dependent phospholipase A2 by insulin secretagogues in isolated pancreatic islets
1993
SB-505124 Is a Selective Inhibitor of Transforming Growth Factor-β Type I Receptors ALK4, ALK5, and ALK7
2004
Interleukin-1β Stimulation of c-Jun NH2-Terminal Kinase Activity in Insulin-Secreting Cells
2001
Extracellular Mediators in Atherosclerosis and Thrombosis
2003