Citation Impact
Citing Papers
Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma
2005
Characterization of MicroRNA Expression Levels and Their Biological Correlates in Human Cancer Cell Lines
2007 StandoutNobel
PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors
2003 StandoutScience
Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma
2009 Standout
Small-Molecule Inhibitors of Phosphatidylinositol 3-Kinase/Akt Signaling Inhibit Wnt/β-Catenin Pathway Cross-Talk and Suppress Medulloblastoma Growth
2009
Targeted Replacement of Hypoxia-Inducible Factor-1α by a Hypoxia-Inducible Factor-2α Knock-in Allele Promotes Tumor Growth
2005
Comprehensive genomic characterization of head and neck squamous cell carcinomas
2015 StandoutNature
Hypoxia-Inducible Factors, Stem Cells, and Cancer
2007
High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
2011 StandoutNobel
HIF-2α regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth
2006
Concordant Regulation of Gene Expression by Hypoxia and 2-Oxoglutarate-dependent Dioxygenase Inhibition
2006 StandoutNobel
The Hypoxia-Associated Factor Switches Cells from HIF-1α- to HIF-2α-Dependent Signaling Promoting Stem Cell Characteristics, Aggressive Tumor Growth and Invasion
2011
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
2009 StandoutNobel
The impact of O2 availability on human cancer
2008
The Hypoxia-Inducible Factor 2α N-Terminal and C-Terminal Transactivation Domains Cooperate To Promote Renal Tumorigenesis In Vivo
2007 StandoutNobel
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia
2013 Standout
Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449
2009 Standout
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
2009 Standout
The von Hippel–Lindau tumour suppressor protein: O2 sensing and cancer
2008 StandoutNobel
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
HIF-Dependent Antitumorigenic Effect of Antioxidants In Vivo
2007 StandoutNobel
Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype
2006
CD155/PVR plays a key role in cell motility during tumor cell invasion and migration
2004
HEDGEHOG-GLI1 Signaling Regulates Human Glioma Growth, Cancer Stem Cell Self-Renewal, and Tumorigenicity
2006
HIFs, Hypoxia, and Vascular Development
2004
Head and neck cancer
2008 Standout
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death
2009
Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression
2004
Early diagnostic and prognostic significance of a specific Th1/Th2 cytokine pattern in children with haemophagocytic syndrome
2008
Procalcitonin assay in systemic inflammation, infection, and sepsis: Clinical utility and limitations
2008
A crucial function of PDGF in TGF-β-mediated cancer progression of hepatocytes
2006
Oncogenic pathway signatures in human cancers as a guide to targeted therapies
2005 StandoutNature
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
2010 StandoutNature
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Cancer genes and the pathways they control
2004 Standout
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
2008 Standout
Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis
2012 StandoutNobel
The Molecular and Genetic Basis of Neurological Tumours
2002
Molecular Analysis of Glioblastoma: Pathway Profiling and Its Implications for Patient Therapy
2003
Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer
2013 StandoutNobel
Medulloblastoma in childhood: new biological advances
2007
Four-and-a-Half LIM Domain Proteins Inhibit Transactivation by Hypoxia-inducible Factor 1
2012 StandoutNobel
Regulation of cancer cell metabolism
2011 Standout
Failure to prolyl hydroxylate hypoxia‐inducible factor α phenocopies VHL inactivation in vivo
2006 StandoutNobel
Hypoxia Inducible Factor 1-α Regulates of Platelet Derived Growth Factor-B in Human Glioblastoma Cells
2005
Heterogeneous Effects of Direct Hypoxia Pathway Activation in Kidney Cancer
2015 StandoutNobel
Gli and hedgehog in cancer: tumours, embryos and stem cells
2002
A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function
2008 Standout
Met, metastasis, motility and more
2003 Standout
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
The t(4;22)(q12;q11) in atypical chronic myeloid leukaemia fuses BCR to PDGFRA
2002
Hsp70 and CHIP Selectively Mediate Ubiquitination and Degradation of Hypoxia-inducible Factor (HIF)-1α but Not HIF-2α
2009 StandoutNobel
Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial
2010 Standout
Coexpression Analysis of Human Genes Across Many Microarray Data Sets
2004
Hedgehog–Gli signaling in brain tumors: stem cells and paradevelopmental programs in cancer
2003
MicroRNA expression profiles classify human cancers
2005 StandoutNatureNobel
Identification of molecular subtypes of glioblastoma by gene expression profiling
2003
Comprehensive Dissection of PDGF-PDGFR Signaling Pathways in PDGFR Genetically Defined Cells
2008
Mitochondrial TCA cycle metabolites control physiology and disease
2020 Standout
Small molecule tyrosine kinase inhibitors: clinical development of anticancer agents
2003
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
The prognostic landscape of genes and infiltrating immune cells across human cancers
2015 Standout
Molecular portraits and the family tree of cancer
2002
The kinesin KIF1Bβ acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor
2008 StandoutNobel
Advances in the Diagnosis, Molecular Genetics, and Treatment of Pediatric Embryonal CNS Tumors
2003
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity
2009 Standout
Binding of Ovarian Cancer Antigen CA125/MUC16 to Mesothelin Mediates Cell Adhesion
2004 Standout
DNA Microarrays in Clinical Oncology
2002
Genomics Identifies Medulloblastoma Subgroups That Are Enriched for Specific Genetic Alterations
2006
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
A molecular fingerprint for medulloblastoma.
2003
Hypoxia-Inducible Factor 1 and Dysregulated c-Myc Cooperatively Induce Vascular Endothelial Growth Factor and Metabolic Switches Hexokinase 2 and Pyruvate Dehydrogenase Kinase 1
2007 StandoutNobel
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
2007 Standout
The Origins of Medulloblastoma Subtypes
2008
Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme
2005
Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
2003 Standout
Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells
2012 StandoutNobel
Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α
2008 StandoutNobel
Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression
2004
Cancerous stem cells can arise from pediatric brain tumors
2003 Standout
Hypoxia and HIF1α Repress the Differentiative Effects of BMPs in High-Grade Glioma
2008
Classification of human astrocytic gliomas on the basis of gene expression: a correlated group of genes with angiogenic activity emerges as a strong predictor of subtypes.
2003
Works of Christopher Lawlor being referenced
Overexpression of the EGFR/FKBP12/HIF-2alpha pathway identified in childhood astrocytomas by angiogenesis gene profiling.
2003
Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease
2001
Interleukin-6, interleukin-8, and a rapid and sensitive assay for calcitonin precursors for the determination of bacterial sepsis in febrile neutropenic children
2005