Citation Impact
Citing Papers
Rapid compaction during RNA folding
2002
Loss of conformational entropy in protein folding calculated using realistic ensembles and its implications for NMR-based calculations
2014 StandoutNobel
Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water
2017 StandoutScienceNobel
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Voltage sensor conformations in the open and closed states in rosetta structural models of K + channels
2006 StandoutNobel
Origins of coevolution between residues distant in protein 3D structures
2017 StandoutNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Structural inference of native and partially folded RNA by high-throughput contact mapping
2008 StandoutNobel
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase
2003
On the Role of a Conserved Methionine in the Na+-Coupling Mechanism of a Neurotransmitter Transporter Homolog
2021
Mutational scanning reveals the determinants of protein insertion and association energetics in the plasma membrane
2016
Alpha helix capping in synthetic model peptides by reciprocal side chain–main chain interactions: Evidence for an N terminal “capping box”
1994
A Thermodynamic Scale for the .beta.-Sheet Forming Tendencies of the Amino Acids
1994
Evolutionary conservation in protein folding kinetics
2000 StandoutNobel
The Highly Cooperative Folding of Small Naturally Occurring Proteins Is Likely the Result of Natural Selection
2007 StandoutNobel
Asparagine-mediated self-association of a model transmembrane helix.
2000
Reconstitution of Hepatitis C Virus Envelope Glycoproteins into Liposomes as a Surrogate Model to Study Virus Attachment
2002
Sequence specificity in the dimerization of transmembrane .alpha.-helixes
1992
An antibiotic factory caught in action
2004
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
Proline-induced Distortions of Transmembrane Helices
2002
A Peptide Derived from a β2-Adrenergic Receptor Transmembrane Domain Inhibits Both Receptor Dimerization and Activation
1996
In VitroStudies of Membrane Protein Folding
2001
Conserved signature proposed for folding in the lipocalin superfamily
2003
New potential binding determinant for hERG channel inhibitors
2016
Central Pore Residues Mediate the p97/VCP Activity Required for ERAD
2006
The dimerization motif of the glycophorin A transmembrane segment in membranes: Importance of glycine residues
1998
Electrostatic interactions between transmembrane segments mediate folding of Shaker K+ channel subunits
1997
A structure-based computational workflow to predict liability and binding modes of small molecules to hERG
2020 StandoutNobel
Room to Move: Crystallizing Membrane Proteins in Swollen Lipidic Mesophases
2006
Saturation of the Endocytic Pathway for the Transferrin Receptor Does Not Affect the Endocytosis of the Epidermal Growth Factor Receptor
1997 StandoutNobel
Fast and Slow Intermediate Accumulation and the Initial Barrier Mechanism in Protein Folding
2002
Role of the molten globule state in protein folding
2000
Constitutive Activation of the β2 Adrenergic Receptor Alters the Orientation of Its Sixth Membrane-spanning Segment
1997
Differential control of band 3 lateral and rotational mobility in intact red cells.
1994 StandoutNobel
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel
1995
Structural studies of the putative helix 8 in the human β2 adrenergic receptor: an NMR study
2004
Early Collapse is not an Obligate Step in Protein Folding
2004
The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex
1995 StandoutNobel
Design of Monomeric Water-Soluble β-Hairpin and β-Sheet Peptides
2014
Uncovering the intimate relationship between lipids, cholesterol and GPCR activation
2011
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
Sar1p N-Terminal Helix Initiates Membrane Curvature and Completes the Fission of a COPII Vesicle
2005 StandoutNobel
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
Fully Reduced Ribonuclease A Does not Expand at High Denaturant Concentration or Temperature
2007
Molecular Determinants of hERG Channel Block by Terfenadine and Cisapride
2008
The Role of the Pleckstrin Homology Domain in Membrane Targeting and Activation of Phospholipase Cβ1
2000
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
The Membrane- and Soluble-Protein Helix-Helix Interactome: Similar Geometry via Different Interactions
2015
Computational investigations of hERG channel blockers: New insights and current predictive models
2015
How do small single-domain proteins fold?
1998
Interhelical hydrogen bonding drives strong interactions in membrane proteins.
2000
A surprising simplicity to protein folding
2000 StandoutNatureNobel
Surface topography dependence of biomolecular hydrophobic hydration
1998 Nature
Magainins as paradigm for the mode of action of pore forming polypeptides
1998
The burst phase in ribonuclease A folding and solvent dependence of the unfolded state
1998
The Crystal Structure of Yeast Fatty Acid Synthase, a Cellular Machine with Eight Active Sites Working Together
2007 StandoutNobel
Effect of Band 3 Subunit Equilibrium on the Kinetics and Affinity of Ankyrin Binding to Erythrocyte Membrane Vesicles
1998
An emerging pharmacology of peptide toxins targeted against potassium channels
1988
Toward high-resolution prediction and design of transmembrane helical protein structures
2007 StandoutNobel
Nonpolar solutes enhance water structure within hydration shells while reducing interactions between them
2005 StandoutNobel
The single transmembrane segment of gp210 is sufficient for sorting to the pore membrane domain of the nuclear envelope.
1992 StandoutNobel
Effect of Ions on the Structure of Water: Structure Making and Breaking
2009 Standout
The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na + channels
2004 StandoutNobel
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles
2003 StandoutNobel
Medicinal Chemistry of hERG Optimizations: Highlights and Hang-Ups
2006
Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs
2004
Reconstitution and functional comparison of purified GlpF and AqpZ, the glycerol and water channels from Escherichia coli
2001 StandoutNobel
Global properties of the mapping between local amino acid sequence and local structure in proteins.
1996 StandoutNobel
Lipid–protein interactions in DHPC micelles containing the integral membrane protein OmpX investigated by NMR spectroscopy
2002 StandoutNobel
Mutant Potassium Channels with Altered Binding of Charybdotoxin, a Pore-Blocking Peptide Inhibitor
1989 StandoutScienceNobel
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor
2012 StandoutNobel
Functional dissection of the CD21/CD19/TAPA-1/Leu-13 complex of B lymphocytes.
1993
Structural Reorganization of Phospholipid Headgroups upon Recrystallization of an S-Layer Lattice
2002
MEMBRANE PROTEIN FOLDING AND STABILITY: Physical Principles
1999
ENDOCYTOSIS AND MOLECULAR SORTING
1996
Chiroptical Molecular Switches
2000 StandoutNobel
Biomembrane mimetic systems
1995
Structure-based conformational preferences of amino acids
1999 StandoutNobel
Effective energy function for proteins in lipid membranes
2003
Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles
2012 Standout
THE STRUCTURAL BIOLOGY OF TYPE II FATTY ACID BIOSYNTHESIS
2005
The first membrane spanning region of the lamin B receptor is sufficient for sorting to the inner nuclear membrane.
1993 StandoutNobel
The third helix of the Antennapedia homeodomain translocates through biological membranes.
1994 Standout
Agonist-induced conformational changes in the G-protein-coupling domain of the β 2 adrenergic receptor
2001 StandoutNobel
Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity
2000 StandoutNobel
Mouse VAP33 is associated with the endoplasmic reticulum and microtubules
2000 StandoutNobel
CHARMM36 all-atom additive protein force field: Validation based on comparison to NMR data
2013 Standout
Dimerization of the Erythropoietin Receptor Transmembrane Domain in Micelles
2006
Anthrolysin O and Other Gram-positive Cytolysins Are Toll-like Receptor 4 Agonists
2004
Mechanisms of membrane deformation
2003
Prediction of membrane protein structures with complex topologies using limited constraints
2009 StandoutNobel
Activation of naïve B lymphocytes via CD81, a pathogenetic mechanism for hepatitis C virus-associated B lymphocyte disorders
2005 StandoutNobel
Development of Safe Drugs: The hERG Challenge
2017
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Modeling of Open, Closed, and Open-Inactivated States of the hERG1 Channel: Structural Mechanisms of the State-Dependent Drug Binding
2012
Self-catalyzed growth of S layers via an amorphous-to-crystalline transition limited by folding kinetics
2010 StandoutNobel
Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy
2015 StandoutNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Docking Model of Drug Binding to the Human Ether-à-go-go Potassium Channel Guided by Tandem Dimer Mutant Patch-Clamp Data: A Synergic Approach
2009
Limited internal friction in the rate-limiting step of a two-state protein folding reaction
1998 StandoutNobel
Hydrophobic Effects and Modeling of Biophysical Aqueous Solution Interfaces
2002
Works of Christopher E. Dempsey being referenced
Structural implications of hERG K+ channel block by a high-affinity minimally structured blocker
2018
Interactions between amiodarone and the hERG potassium channel pore determined with mutagenesis and in silico docking
2016
Structure, Location, and Lipid Perturbations of Melittin at the Membrane Interface
2001
Arginine side chain interactions and the role of arginine as a gating charge carrier in voltage sensitive ion channels
2016
Topology, sequence evolution and folding dynamics of an immunoglobulin domain
1998
Helix bending in alamethicin: molecular dynamics simulations and amide hydrogen exchange in methanol
1997
A combined X-ray and neutron diffraction study of selectively deuterated melittin in phospholipid bilayers: effect of pH
1994
Preferential closed channel blockade of HERG potassium currents by chemically synthesised BeKm‐1 scorpion toxin
2003
Weak interaction of spectrin with phosphatidylcholine‐phosphatidylserine multilayers: A 2H and 31P NMR study
1989
Direct Kinetic Evidence for Folding via a Highly Compact, Misfolded State
1999
Helical structure and orientation of melittin in dispersed phospholipid membranes from amide exchange analysis in situ
1992
The Low-Potency, Voltage-Dependent HERG Blocker Propafenone—Molecular Determinants and Drug Trapping
2004
Contribution of proline‐14 to the structure and actions of melittin
1991
The actions of melittin on membranes
1990
Ranolazine inhibition of hERG potassium channels: Drug–pore interactions and reduced potency against inactivation mutants
2014
Distinct subcellular localisations of the putative inositol 1,3,4,5-tetrakisphosphate receptors GAP1 IP4BP and GAP1 m result from the GAP1 IP4BP PH domain directing plasma membrane targeting
1997
Insight into Indole Interactions from Alkali Metal Chloride Effects on a Tryptophan Zipper β-Hairpin Peptide
2006
pH Dependence of hydrogen exchange from backbone peptide amides of melittin in methanol
1988
Solution Structure of the Actinorhodin Polyketide Synthase Acyl Carrier Protein from Streptomyces coelicolor A3(2),
1997
Evidence from deuterium nuclear magnetic resonance for the temperature-dependent reversible self-association of erythrocyte band 3 in dimyristoylphosphatidylcholine bilayers
1986
New methods of isolating bee venom peptides
1981
The hydration structure of guanidinium and thiocyanate ions: Implications for protein stability in aqueous solution
2003
Protein-lipid interactions at membrane surfaces: a deuterium and phosphorus nuclear magnetic resonance study of the interaction between bovine rhodopsin and the bilayer head groups of dimyristoylphosphatidylcholine
1986
The solution structures of the first and second transmembrane‐spanning segments of band 3
1994
Glycophorin A dimerization is driven by specific interactions between transmembrane alpha-helices.
1992
The Structure of Aqueous Guanidinium Chloride Solutions
2004
Assessing hERG Pore Models As Templates for Drug Docking Using Published Experimental Constraints: The Inactivated State in the Context of Drug Block
2014
Acquisition of Native β-Strand Topology During the Rapid Collapse Phase of Protein Folding
1997
The tyrosine-containing internalization motif in the cytoplasmic domain of TGN38/41 lies within a nascent helix.
1994