Citation Impact
Citing Papers
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes
2020 StandoutNobel
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
2016 StandoutScience
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
CRISPR/Cas9 in Genome Editing and Beyond
2016
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
Structures of the CRISPR genome integration complex
2017 StandoutScienceNobel
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
De novo design and directed folding of disulfide-bridged peptide heterodimers
2022 StandoutNobel
Improved gRNA secondary structures allow editing of target sites resistant to CRISPR-Cas9 cleavage
2022 StandoutNobel
Nucleoside-modified VEGFC mRNA induces organ-specific lymphatic growth and reverses experimental lymphedema
2021 StandoutNobel
The CRISPR tool kit for genome editing and beyond
2018
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Orthogonal Genetic Regulation in Human Cells Using Chemically Induced CRISPR/Cas9 Activators
2017
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
2019 StandoutNobel
Engineering precision nanoparticles for drug delivery
2020 Standout
Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions
2024 StandoutNobel
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity
2020 StandoutNobel
Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements
2015
A multifunctional AAV–CRISPR–Cas9 and its host response
2016
Editing the epigenome: technologies for programmable transcription and epigenetic modulation
2016
A tunable orthogonal coiled-coil interaction toolbox for engineering mammalian cells
2020
In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation
2017
Complex transcriptional modulation with orthogonal and inducible dCas9 regulators
2016
Hydrophobic mismatch drives self-organization of designer proteins into synthetic membranes
2024 StandoutNobel
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
2014 Standout
Multi-input chemical control of protein dimerization for programming graded cellular responses
2019 StandoutNobel
Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators
2015
Genome-Editing Technologies: Principles and Applications
2016
A CRISPR–dCas Toolbox for Genetic Engineering and Synthetic Biology
2018
Comparison of Cas9 activators in multiple species
2016
Genetic engineering of T cells for immunotherapy
2021
Inducible and multiplex gene regulation using CRISPR–Cpf1-based transcription factors
2017
Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation
2017
Evolved Cas9 variants with broad PAM compatibility and high DNA specificity
2018 Nature
Large-scale design of robust genetic circuits with multiple inputs and outputs for mammalian cells
2017
Multiplexable, locus-specific targeting of long RNAs with CRISPR-Display
2015
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Enabling functional genomics with genome engineering
2015
Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
2015
Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system
2017
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
Engineering an allosteric transcription factor to respond to new ligands
2015 StandoutNobel
Orthologous CRISPR–Cas9 enzymes for combinatorial genetic screens
2017
Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)–mediated induction of the long noncoding RNA NICI
2019 StandoutNobel
Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch
2016 StandoutNobel
High-Throughput Approaches to Pinpoint Function within the Noncoding Genome
2017
Cas9 gRNA engineering for genome editing, activation and repression
2015
Beyond editing: repurposing CRISPR–Cas9 for precision genome regulation and interrogation
2015
Targeted transcriptional modulation with type I CRISPR–Cas systems in human cells
2019
Rational designs of in vivo CRISPR-Cas delivery systems
2019
Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity
2016
Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies
2020
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
A thermostable Cas9 with increased lifetime in human plasma
2017 StandoutNobel
The next generation of CRISPR–Cas technologies and applications
2019
Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing
2019
A new era in functional genomics screens
2021
Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation
2020 StandoutNobel
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes
2017 StandoutNobel
Genome Editing with mRNA Encoding ZFN, TALEN, and Cas9
2019
Mutations in Cas9 Enhance the Rate of Acquisition of Viral Spacer Sequences during the CRISPR-Cas Immune Response
2016 StandoutNobel
Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9
2016 StandoutNobel
Massively parallel kinetic profiling of natural and engineered CRISPR nucleases
2020 StandoutNobel
CRISPR/Cas9-Mediated Genome Editing of Epigenetic Factors for Cancer Therapy
2015
CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine
2017
Systematic discovery of natural CRISPR-Cas12a inhibitors
2018 StandoutScienceNobel
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
CRISPR Correction of Duchenne Muscular Dystrophy
2018
Molecular recordings by directed CRISPR spacer acquisition
2016 Science
Modular repeat protein sculpting using rigid helical junctions
2020 StandoutNobel
The STRING database in 2023: protein–protein association networks and functional enrichment analyses for any sequenced genome of interest
2022 Standout
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Engineering of temperature- and light-switchable Cas9 variants
2013 StandoutNobel
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
Cellular uptake of nanoparticles: journey inside the cell
2017 Standout
De novo design of protein homodimers containing tunable symmetric protein pockets
2022 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
CRISPOR: intuitive guide selection for CRISPR/Cas9 genome editing experiments and screens
2018 Standout
De novo design of protein logic gates
2020 StandoutScienceNobel
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation
2016
Works of Christopher D. Guzman being referenced
Highly efficient Cas9-mediated transcriptional programming
2015
Synthetic biosensors for precise gene control and real-time monitoring of metabolites
2015
Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells
2019
AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma
2017