Citation Impact
Citing Papers
Signal transduction and regulation in smooth muscle
1994 StandoutNature
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Control of excitatory synaptic transmission by capsaicin is unaltered in TRPV1 vanilloid receptor knockout mice
2007
Postsynaptic TRPV1 triggers cell type–specific long-term depression in the nucleus accumbens
2010
Inositol trisphosphate, calcium and muscle contraction
1988
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Lessons from peppers and peppermint: the molecular logic of thermosensation
2003 StandoutNobel
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Molecular Determinants of Permeation through the Cation Channel TRPV4
2002
Pharmacology and electrophysiology of ATP-activated ion channels
1992
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
Reduced Anxiety, Conditioned Fear, and Hippocampal Long-Term Potentiation in Transient Receptor Potential Vanilloid Type 1 Receptor-Deficient Mice
2007
Cationic channels activated by extracellular atp in rat sensory neurons
1988
Thermodynamics of Heat Activation of Single Capsaicin Ion Channels VR1
2003
Increased Basal Activity Is a Key Determinant in the Severity of Human Skeletal Dysplasia Caused by TRPV4 Mutations
2011
TRPV3 and TRPV4 Mediate Warmth-evoked Currents in Primary Mouse Keratinocytes
2004
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Functional and physical coupling of voltage‐sensitive calcium channels with exocytotic proteins: ramifications for the secretion mechanism
2001
Forward Genetic Analysis Reveals Multiple Gating Mechanisms of TRPV4
2010
The capsaicin receptor: a heat-activated ion channel in the pain pathway
1997 StandoutNatureNobel
ATP mediates fast synaptic transmission in mammalian neurons
1992 Nature
Transient receptor potential ion channels as participants in thermosensation and thermoregulation
2006
Purine-mediated signalling in pain and visceral perception
2001
TRP channels and lipids: from Drosophila to mammalian physiology
2006
ThermoTRP channels and beyond: mechanisms of temperature sensation
2003 StandoutNobel
Pore region of TRPV3 ion channel is specifically required for heat activation
2008 StandoutNobel
2-Aminoethoxydiphenyl Borate Is a Common Activator of TRPV1, TRPV2, and TRPV3
2004
Opposite thermosensor in fruitfly and mouse
2003 StandoutNatureNobel
Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain
2006
Zebrafish TRPA1 Channels Are Required for Chemosensation But Not for Thermosensation or Mechanosensory Hair Cell Function
2008 StandoutNobel
Anandamide and vanilloid TRPV1 receptors
2003
A capsaicin-receptor homologue with a high threshold for noxious heat
1999 StandoutNatureNobel
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
1999 StandoutNatureNobel
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels
2004 Nature
Piezo proteins are pore-forming subunits of mechanically activated channels
2012 StandoutNatureNobel
Structure–functional intimacies of transient receptor potential channels
2009
2-Aminoethoxydiphenyl Borate Activates and Sensitizes the Heat-Gated Ion Channel TRPV3
2004
Eating disorder and epilepsy in mice lacking 5-HT2C serotonin receptors
1995 StandoutNatureNobel
Cell death and proliferation in acute slices and organotypic cultures of mammalian CNS
2009
Targeting TRP channels for pain relief
2013
Calcium-activated K+ channels: Metabolic regulation
1991
Regulation of calcium influx by second messengers in rat mast cells
1988 StandoutNatureNobel
Optical Control of TRPV1 Channels
2013
Localization of mechanosensitive channel TRPV4 in mouse skin
2003
A 3.5-nm Structure of Rat TRPV4 Cation Channel Revealed by Zernike Phase-contrast Cryoelectron Microscopy
2010
Nociceptors Lacking TRPV1 and TRPV2 Have Normal Heat Responses
2004
Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents
2000 Nature
Energetic optimization of ion conduction rate by the K+ selectivity filter
2001 StandoutNatureNobel
International Union of Basic and Clinical Pharmacology. LXXVI. Current Progress in the Mammalian TRP Ion Channel Family
2010
From chills to chilis: mechanisms for thermosensation and chemesthesis via thermoTRPs
2007 StandoutNobel
ATP-activated single-channel currents recorded from cell-free patches of pheochromocytoma PC12 cells
1990
4-(2-Pyridyl)piperazine-1-carboxamides: potent vanilloid receptor 1 antagonists
2003
Calcium Channels, Stores, and Oscillations
1990
New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor
1994 StandoutNatureNobel
Molecular Determinants of Species-Specific Activation or Blockade of TRPA1 Channels
2008
Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle
1994 StandoutNature
Effects of ATP antagonists on purinoceptor-operated inward currents in rat phaeochromocytoma cells
1991
Electrostatic tuning of Mg2+ affinity in an inward-rectifier K+channel
1994 StandoutNatureNobel
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
TRP channels as cellular sensors
2003 StandoutNature
TRPV1
2014
Two functionally distinct α2-adrenergic receptors regulate sympathetic neurotransmission
1999 StandoutNatureNobel
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Molecular basis of infrared detection by snakes
2010 StandoutNatureNobel
Camphor Activates and Strongly Desensitizes the Transient Receptor Potential Vanilloid Subtype 1 Channel in a Vanilloid-Independent Mechanism
2005
Two Interdependent TRPV Channel Subunits, Inactive and Nanchung, Mediate Hearing in Drosophila
2004
Activation of a TRPC3-Dependent Cation Current through the Neurotrophin BDNF
1999
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
2001 StandoutNatureNobel
2002
The TRPC3/6/7 subfamily of cation channels
2003
Molecular and Functional Characterization of the Melastatin-related Cation Channel TRPM3
2003
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
2002 StandoutNatureNobel
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus
2010
Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression
1998 StandoutNatureNobel
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels
2003 Nature
The epithelial calcium channels, TRPV5 & TRPV6: from identification towards regulation
2003
Expression and distribution of vanilloid receptor 1 (TRPV1) in the adult rat brain
2005
Receptor-activated Ca2+ influx: how many mechanisms for how many channels?
1994
Vanilloid Receptor–Related Osmotically Activated Channel (VR-OAC), a Candidate Vertebrate Osmoreceptor
2000 Standout
Epidermal growth factor activates calcium channels by phospholipase A25-lipoxygenase-mediated leukotriene C4 production
1992
Biphasic Currents Evoked by Chemical or Thermal Activation of the Heat-gated Ion Channel, TRPV3
2005
The menthol receptor TRPM8 is the principal detector of environmental cold
2007 StandoutNatureNobel
Endovanilloids
2004
Lack of evidence for functional TRPV1 vanilloid receptors in rat hippocampal nerve terminals
2006
Activation of ATP P2X receptors elicits glutamate release from sensory neuron synapses
1997 Nature
Warm Temperature-sensitive Transient Receptor Potential Vanilloid 4 (TRPV4) Plays an Essential Role in Thermal Hyperalgesia
2004
Sensing with TRP channels
2005
Activation Properties of Heterologously Expressed Mammalian TRPV2
2007
The role of Drosophila Piezo in mechanical nociception
2012 StandoutNatureNobel
A TRPV family ion channel required for hearing in Drosophila
2003 Nature
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
2004 StandoutNatureNobel
Trpv1 Reporter Mice Reveal Highly Restricted Brain Distribution and Functional Expression in Arteriolar Smooth Muscle Cells
2011 StandoutNobel
Spider toxins activate the capsaicin receptor to produce inflammatory pain
2006 StandoutNatureNobel
Acid‐sensing ion channels ASIC2 and ASIC3 do not contribute to mechanically activated currents in mammalian sensory neurones
2004
Ion channel and receptor mechanisms of bladder afferent nerve sensitivity
2009
Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx
1993 StandoutNatureNobel
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
Current understanding of mammalian TRP homologues
2002
TRPV3 is a temperature-sensitive vanilloid receptor-like protein
2002 Nature
Organotypic cultures as tools for functional screening in the CNS
2005
Hypotonicity Induces TRPV4-Mediated Nociception in Rat
2003
Pharmacology of Vanilloid Transient Receptor Potential Cation Channels
2009
TRPV1 Channels Mediate Long-Term Depression at Synapses on Hippocampal Interneurons
2008
Identification of the platelet ADP receptor targeted by antithrombotic drugs
2001 StandoutNatureNobel
Calcium signaling
1995 Standout
Mechanisms of intracellular protein transport
1994 StandoutNatureNobel
Capacitative calcium entry revisited
1990
TRPV3 is a calcium-permeable temperature-sensitive cation channel
2002 Nature
Impaired Pressure Sensation in Mice Lacking TRPV4
2003
α-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis
2003 StandoutNatureNobel
Overview: Purinergic Mechanisms
1990
Modulation of voltage-dependent Ca channel current by arachidonic acid and other long-chain fatty acids in rabbit intestinal smooth muscle.
1992
1990: Annus Mirabilis of Potassium Channels
1991 Science
Coupling between intracellular Ca2+ stores and the Ca2+ permeability of the plasma membrane. Comparison of the effects of thapsigargin, 2,5-di-(tert-butyl)-1,4-hydroquinone, and cyclopiazonic acid in rat thymic lymphocytes.
1991
Modular thermal sensors in temperature-gated transient receptor potential (TRP) channels
2011
An ATP‐activated conductance in pheochromocytoma cells and its suppression by extracellular calcium.
1990
Evolution of thermoTRP ion channel homologs in vertebrates
2006
PERMEATION AND SELECTIVITY OF TRP CHANNELS
2005
Basic mechanisms and local modulation of nerve impulse-induced secretion of neurotransmitters from individual sympathetic nerve varicosities
2005
Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes
2017
Characterization of calcium-activated potassium channels in single smooth muscle cells using the patch-clamp technique
1987
Cytochrome P450 may regulate plasma membrane Ca 2+ permeability according to the filling state of the intracellular Ca 2+ stores
1992
The exocytotic fusion pore.
1992
The TRP Superfamily of Cation Channels
2005
Mechanisms of NE-induced reduction of Ca current in single smooth muscle cells from guinea pig vas deferens
1991
Regulation of Arterial Tone by Activation of Calcium-Dependent Potassium Channels
1992 Science
The Ca signal from fura‐2 loaded mast cells depends strongly on the method of dye‐loading
1985 StandoutNobel
Adenosine triphosphate‐evoked currents in cultured neurones dissociated from rat parasympathetic cardiac ganglia.
1991
Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor
2000 StandoutScienceNobel
Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms
2018
Structure–function relationship of the TRP channel superfamily
2006
Muscarinic Response In Rat Lacrimal Glands
1986
Potassium blocks barium permeation through a calcium-activated potassium channel.
1988
Calcium Rises Abruptly and Briefly Throughout the Cell at the Onset of Anaphase
1986 StandoutScienceNobel
Impaired Thermosensation in Mice Lacking TRPV3, a Heat and Camphor Sensor in the Skin
2005 StandoutScienceNobel
Permeation of both cations and anions through a single class of ATP-activated ion channels in developing chick skeletal muscle.
1990
Hot Receptors in the Brain
2006
Rapid Activation of Protein Tyrosine Kinase and Phospholipase C-γ2 and Increase in Cytosolic Free Calcium Are Required byEhrlichia chaffeensisfor Internalization and Growth in THP-1 Cells
2002
CHEMICAL ACTIVATORS OF SENSORY NEURONS
1997
Optische Kontrolle von TRPV1‐Kanälen
2013
AN INTRODUCTION TO TRP CHANNELS
2005 Standout
TRP ION CHANNELS AND TEMPERATURE SENSATION
2006 StandoutNobel
Impaired osmotic sensation in mice lacking TRPV4
2003
Functional characterization of transient receptor potential channels in mouse urothelial cells
2009
Inhibition of Ca2+ transport pathways in thymic lymphocytes by econazole, miconazole, and SKF 96365
1993
Emerging Targets in Photopharmacology
2016 StandoutNobel
The role of intracellular Ca2+ in the regulation of the plasma membrane Ca2+ permeability of unstimulated rat lymphocytes
1991
Block by calcium of ATP-activated channels in pheochromocytoma cells.
1993
Heat-Evoked Activation of the Ion Channel, TRPV4
2002
A Heat-Sensitive TRP Channel Expressed in Keratinocytes
2002 StandoutScienceNobel
Structural and Biochemical Consequences of Disease-Causing Mutations in the Ankyrin Repeat Domain of the Human TRPV4 Channel
2012
Calcium channels, potassium channels, and voltage dependence of arterial smooth muscle tone
1990
TRP Channels
2007 Standout
An ATP‐sensitive conductance in single smooth muscle cells from the rat vas deferens.
1988
Extracellular nucleotides mediate Ca2+ fluxes in J774 macrophages by two distinct mechanisms.
1988
Role and regulation of TRP channels in neutrophil granulocytes
2003
Works of Christopher D. Benham being referenced
The diversity in the vanilloid (TRPV) receptor family of ion channels
2002
Stretch‐induced injury in organotypic hippocampal slice cultures reproduces in vivo post‐traumatic neurodegeneration: role of glutamate receptors and voltage‐dependent calcium channels
2006
Caspase inhibitors are functionally neuroprotective against oxygen glucose deprivation induced CA1 death in rat organotypic hippocampal slices
2000
[3H]Resiniferatoxin autoradiography in the CNS of wild-type and TRPV1 null mice defines TRPV1 (VR-1) protein distribution
2003
Recent Advances in the Molecular Understanding of Voltage-Gated Ca2+ Channels
1999
Heat-evoked Activation of TRPV4 Channels in a HEK293 Cell Expression System and in Native Mouse Aorta Endothelial Cells
2002
Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy
2007
Cloning and Functional Expression of Human Short TRP7, a Candidate Protein for Store-operated Ca2+ Influx
2002
TRPV channels as temperature sensors
2003
Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations
2006
TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP‐ribose) polymerase
2004
Sensing of Lysophospholipids by TRPC5 Calcium Channel
2005
Flufenamic acid is a pH-dependent antagonist of TRPM2 channels
2004
mRNA distribution analysis of human TRPC family in CNS and peripheral tissues
2002
Calcium Influx Induced by Stimulation of ATP Receptors on Neurons Cultured from Rat Dorsal Root Ganglia
1991
Activation of TRPV4 Channels (hVRL-2/mTRP12) by Phorbol Derivatives
2002
Calpain activation and inhibition in organotypic rat hippocampal slice cultures deprived of oxygen and glucose
1999
A novel receptor-operated Ca2+-permeable channel activated by ATP in smooth muscle
1987 Nature
Spontaneous transient outward currents in single visceral and vascular smooth muscle cells of the rabbit.
1986
Noradrenaline modulation of calcium channels in single smooth muscle cells from rabbit ear artery.
1988
Calcium‐activated potassium channels in single smooth muscle cells of rabbit jejunum and guinea‐pig mesenteric artery.
1986
The mechanism of action of Ba2+ and TEA on single Ca2+-activated K+-channels in arterial and intestinal smooth muscle cell membranes
1985
Selective N-Type Calcium Channel Antagonist Omega Conotoxin MVIIA Is Neuroprotective Against Hypoxic Neurodegeneration in Organotypic Hippocampal-Slice Cultures
1996
Action of externally applied adenosine triphosphate on single smooth muscle cells dispersed from rabbit ear artery.
1987
Potassium, chloride and non‐selective cation conductances opened by noradrenaline in rabbit ear artery cells.
1990
SK&F 96365, a novel inhibitor of receptor-mediated calcium entry
1990
Voltage‐gated and agonist‐mediated rises in intracellular Ca2+ in rat clonal pituitary cells (GH3) held under voltage clamp.
1989
Control of Secretion in Anterior Pituitary Cells - Linking ion Channels, Messengers and Exocytosis
1988
Vanilloid and TRP channels: a family of lipid-gated cation channels
2002
ATP‐activated channels gate calcium entry in single smooth muscle cells dissociated from rabbit ear artery.
1989
Acetylcholine activates an inward current in single mammalian smooth muscle cells
1985 Nature