Citation Impact
Citing Papers
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
Murine liver repair via transient activation of regenerative pathways in hepatocytes using lipid nanoparticle-complexed nucleoside-modified mRNA
2021 StandoutNobel
Cardiomyocyte-specific Prolyl-4-hydroxylase Domain 2 Knock Out Protects from Acute Myocardial Ischemic Injury
2011
Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
2010 StandoutNobel
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
2009 StandoutNobel
Keeping the engine primed: HIF factors as key regulators of cardiac metabolism and angiogenesis during ischemia
2007
HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine
2015 StandoutNobel
The impact of O2 availability on human cancer
2008
Role of hypoxia-inducible factor in cell survival during myocardial ischemia–reperfusion
2008
Improved heart function follows enhanced inflammatory cell recruitment and angiogenesis in 11βHSD1-deficient mice post-MI
2010
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
2016 StandoutNobel
Megestrol Acetate Stimulates Weight Gain and Ventilation in Underweight COPD Patients
2002
HIF-1 reduces ischaemia–reperfusion injury in the heart by targeting the mitochondrial permeability transition pore
2014
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
2004 StandoutNature
Operative classification of thromboembolic disease determines outcome after pulmonary endarterectomy
2002
Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice
2011 StandoutNobel
Treatment of Pulmonary Arterial Hypertension
2004 Standout
mRNA-Based Protein Replacement Therapy for the Heart
2018
Hypoxia and Inflammation
2011 Standout
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
Cellular and molecular pathobiology of pulmonary arterial hypertension
2004 Standout
Pre- and post-conditional inhibition of prolyl-4-hydroxylase domain enzymes protects the heart from an ischemic insult
2015
Angiogenesis in health and disease
2003 Standout
Conditional HIF-1α Expression Produces a Reversible Cardiomyopathy
2010
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors
2011 StandoutNobel
Hypoxia inducible factor 1 (HIF-1) and cardioprotection
2010
Pulmonary thromboendarterectomy surgery
2004
Tricuspid valvular disease in the patient with chronic pulmonary thromboembolic disease
2003
Angiogenesis in life, disease and medicine
2005 StandoutNature
Cellular and Molecular Basis of Pulmonary Arterial Hypertension
2009
CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION
2001
Endoglin germline mutation in a patient with hereditary haemorrhagic telangiectasia and dexfenfluramine associated pulmonary arterial hypertension
2004
Molecular Biology of Chronic Thromboembolic Pulmonary Hypertension
2006
Depletion of PHD3 protects heart from ischemia/reperfusion injury by inhibiting cardiomyocyte apoptosis
2015
Effects of Iron Supplementation and Depletion on Hypoxic Pulmonary Hypertension
2009 StandoutNobel
Activation of hypoxia-inducible factor-1 via prolyl-4 hydoxylase-2 gene silencing attenuates acute inflammatory responses in postischemic myocardium
2007
Sox18 induces development of the lymphatic vasculature in mice
2008 StandoutNature
The role of autophagy in the heart
2008
Pulmonary Arterial Hypertension
2004
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
Unfavourable consequences of chronic cardiac HIF-1α stabilization
2012
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Outcomes of pulmonary endarterectomy for treatment of extreme thromboembolic pulmonary hypertension
2006
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Pulmonary endarterectomy: experience and lessons learned in 1,500 cases
2003
Hepatic Stellate Cells Secrete Angiopoietin 1 That Induces Angiogenesis in Liver Fibrosis
2008
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system
2009
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease
2009
Chronic thromboembolic pulmonary hypertension
2014
Angiopoietin/Tie2 Pathway Influences Smooth Muscle Hyperplasia in Idiopathic Pulmonary Hypertension
2006
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase
2018 StandoutNobel
Digoxin inhibits development of hypoxic pulmonary hypertension in mice
2012 StandoutNobel
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Clinical iron deficiency disturbs normal human responses to hypoxia
2016 StandoutNobel
Pulmonary Arterial Hypertension
2006
Protective Role of Angiopoietin-1 in Experimental Pulmonary Hypertension
2003
A Feedback Loop Involving the Phd3 Prolyl Hydroxylase Tunes the Mammalian Hypoxic Response In Vivo
2009 StandoutNobel
Management of Massive and Submassive Pulmonary Embolism, Iliofemoral Deep Vein Thrombosis, and Chronic Thromboembolic Pulmonary Hypertension
2011 Standout
Hypoxia-Inducible Factor-Dependent Degeneration, Failure, and Malignant Transformation of the Heart in the Absence of the von Hippel-Lindau Protein
2008
Reactivation of Hepatic EPO Synthesis in Mice After PHD Loss
2010 StandoutScienceNobel
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Chronic Thromboembolic Pulmonary Hypertension
2006 Standout
The angiopietin-1–Tie2 pathway prevents rather than promotes pulmonary arterial hypertension in transgenic mice
2009
Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure
2007 StandoutNobel
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy
2005 StandoutScience
Evaluation and Management of the Patient with Pulmonary Arterial Hypertension
2005
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
Hypoxia. 2. Hypoxia regulates cellular metabolism
2010
Stabilized HIF‐1α is superior to VEGF for angiogenesis in skeletal muscle via adeno‐associated virus gene transfer
2005
Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
2009 StandoutNobel
Signaling and Functions of Angiopoietin-1 in Vascular Protection
2006
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
Inhibition of Hypoxia-Inducible Factor Prolyl Hydroxylase Domain Oxygen Sensors: Tricking the Body into Mounting Orchestrated Survival and Repair Responses
2013
Works of Christopher C. Sullivan being referenced
Gene Delivery to the Mammalian Heart Using AAV Vectors
2004
Hypoxia-Inducible Factor 1-Alpha Reduces Infarction and Attenuates Progression of Cardiac Dysfunction After Myocardial Infarction in the Mouse
2005
Diabetes Mellitus Induced by Megestrol Acetate in a Patient with AIDS and Cachexia
1992
A new animal model for pulmonary hypertension based on the overexpression of a single gene, angiopoietin-1
2004
Signaling Molecules in Nonfamilial Pulmonary Hypertension
2003
Direct comparison of efficiency and stability of gene transfer into the mammalian heart using adeno-associated virus versus adenovirus vectors
2003
Gene transfer of a TIE2 receptor antagonist prevents pulmonary hypertension in rodents
2004
Human angiopoietin gene expression is a marker for severity of pulmonary hypertension in patients undergoing pulmonary thromboendarterectomy
2001
Induction of pulmonary hypertension by an angiopoietin 1/TIE2/serotonin pathway
2003