Citation Impact
Citing Papers
Pathobiology of liver fibrosis: a translational success story
2015
The Desmoplastic Reaction Surrounding Hepatic Colorectal Adenocarcinoma Metastases Aids Tumor Growth and Survival via αv Integrin Ligation
2008
Fibronectin EDA Promotes Chronic Cutaneous Fibrosis Through Toll-Like Receptor Signaling
2014
Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis
2007 Standout
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
2023 StandoutNobel
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
2005
Prevention of rat hepatic fibrosis by the protease inhibitor, camostat mesilate, via reduced generation of active TGF-β
2001
Regulation of hepatic stellate cell proliferation and collagen synthesis by proteinase-activated receptors
2002
Matrix metalloproteinases and the regulation of tissue remodelling
2007 Standout
Adiponectin protects against cerebral ischemia–reperfusion injury through anti-inflammatory action
2009 StandoutNobel
Tissue inhibitor of metalloproteinases-1 attenuates spontaneous liver fibrosis resolution in the transgenic mouse
2002
Flt3 Signaling-Dependent Dendritic Cells Protect against Atherosclerosis
2011 StandoutNobel
Liver fibrosis
2005 Standout
The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis
2005
Integrins in cancer: biological implications and therapeutic opportunities
2009 Standout
Hepatocytes Express Nerve Growth Factor during Liver Injury
2003
Peroxisome Proliferator-activated Receptor γ Induces a Phenotypic Switch from Activated to Quiescent Hepatic Stellate Cells
2004
Mechanisms of hepatic stellate cell activation
2017 Standout
Mechanisms of liver fibrosis
2005
Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice
2011 StandoutNobel
Hepatic Stellate Cells and Liver Fibrosis
2013
Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis
2006
Liver fibrosis – from bench to bedside
2003 Standout
p75 neurotrophin receptor signaling regulates hepatic myofibroblast proliferation and apoptosis in recovery from rodent liver fibrosis†
2008
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Lipid accumulation in hepatocytes induces fibrogenic activation of hepatic stellate cells
2009
TLR4 enhances TGF-β signaling and hepatic fibrosis
2007 Standout
Stress System Activity, Innate and T Helper Cytokines, and Susceptibility to Immune‐Related Diseases
2006
Low-Density Lipoprotein Receptor-Related Protein-1 Mediates Endocytic Clearance of Tissue Inhibitor of Metalloproteinases-1 and Promotes Its Cytokine-Like Activities
2014 StandoutNobel
The biology and function of fibroblasts in cancer
2016 Standout
Macrophages: Master Regulators of Inflammation and Fibrosis
2010 Standout
Hepatic stellate cells and the reversal of fibrosis
2006
Apoptosis: The nexus of liver injury and fibrosis
2004
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
2014 StandoutNature
A Humanized Mouse Model to Study Hepatitis C Virus Infection, Immune Response, and Liver Disease
2011 StandoutNobel
Engagement of αvβ3 Integrin Regulates Proliferation and Apoptosis of Hepatic Stellate Cells
2004
Inhibition of inhibitor of κB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis
2005
Spontaneous recovery from micronodular cirrhosis: Evidence for incomplete resolution associated with matrix cross-linking☆
2004
ADAM metallopeptidase with thrombospondin type 1 motif 2 inactivation reduces the extent and stability of carbon tetrachloride–induced hepatic fibrosis in mice
2007
Pharmacological inhibition of the chemokine C-C motif chemokine ligand 2 (monocyte chemoattractant protein 1) accelerates liver fibrosis regression by suppressing Ly-6C+ macrophage infiltration in mice
2014
A New Role for TIMP-1 in Modulating Neurite Outgrowth and Morphology of Cortical Neurons
2009
JunD is a profibrogenic transcription factor regulated by Jun N-terminal kinase-independent phosphorylation
2006
Matrix metalloproteinases, the pros and cons, in liver fibrosis
2006
Reversal of Fibrosis: No Longer a Pipe Dream?
2006
A simple immunofluorescence technique for simultaneous visualization of mast cells and nerve fibers reveals selectivity and hair cycle - dependent changes in mast cell - nerve fiber contacts in murine skin
1997
Liver fibrosis: Insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors
2003
Immune-Neuro-Endocrine Interactions: Facts and Hypotheses
1996
Induction of myofibroblast MMP-9 transcription in three-dimensional collagen I gel cultures: regulation by NF-κB, AP-1 and Sp1
2003
Liver fibrosis and repair: immune regulation of wound healing in a solid organ
2014
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Tissue inhibitors of metalloproteases: Regulation and biological activities
2000
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
Transcriptional regulation of hepatic stellate cell activation: Figure 1
2002
Molecular and cellular mechanisms of liver fibrosis and its regression
2020
A Role for Serotonin (5-HT) in Hepatic Stellate Cell Function and Liver Fibrosis
2006
DDR2 receptor promotes MMP-2–mediated proliferation and invasion by hepatic stellate cells
2001
Normal and Pathologic Soft Tissue Remodeling: Role of the Myofibroblast, with Special Emphasis on Liver and Kidney Fibrosis
2003
Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
2007 Standout
Fibroblast Differentiation in Wound Healing and Fibrosis
2007
Macrophages in Tissue Repair, Regeneration, and Fibrosis
2016 Standout
Oxidative stress stimulates proliferation and invasiveness of hepatic stellate cells via a MMP2‐mediated mechanism†
2005
Glucocorticoids and the Th1/Th2 Balance
2004
Upstream Tissue Inhibitor of Metalloproteinases-1 (TIMP-1) Element-1, a Novel and Essential Regulatory DNA Motif in the Human TIMP-1 Gene Promoter, Directly Interacts with a 30-kDa Nuclear Protein
2000
Molecular Regulation of Hepatic Fibrosis, an Integrated Cellular Response to Tissue Injury
2000 Standout
The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity
2010
Mechanisms of Hepatic Fibrogenesis
2008 Standout
JunD Regulates Transcription of the Tissue Inhibitor of Metalloproteinases-1 and Interleukin-6 Genes in Activated Hepatic Stellate Cells
2001
Characterization of a Stellate Cell Activation-associated Protein (STAP) with Peroxidase Activity Found in Rat Hepatic Stellate Cells
2001
The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis
2004
Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ
2007
Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis
2004
Reversal of Hepatic Fibrosis — Fact or Fantasy?
2006
Sinusoidal remodeling and angiogenesis: A new function for the liver-specific pericyte?
2007
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
2013 Standout
Remodelling the extracellular matrix in development and disease
2014 Standout
TIMPs as multifacial proteins
2004
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
1998 StandoutNature
TIMP-1 binding to proMMP-9/CD44 complex localized at the cell surface promotes erythroid cell survival
2008
Activated hepatic stellate cells overexpress p75NTR after partial hepatectomy and undergo apoptosis on nerve growth factor stimulation
2006
Fibroblast Activation Protein Increases Apoptosis, Cell Adhesion, and Migration by the LX-2 Human Stellate Cell Line *
2005
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
2012 Standout
Transcriptional regulation of hepatic stellate cells
2009
GFAP promoter directs lacZ expression specifically in a rat hepatic stellate cell line
2006
DLPC and SAMe combined prevent leptin‐stimulated TIMP‐1 production in LX‐2 human hepatic stellate cells by inhibiting H2O2‐mediated signal transduction
2005
Advances in functional and molecular MRI technologies in chronic liver diseases
2020
IgG4-related disease
2014 Standout
A Farnesoid X Receptor-Small Heterodimer Partner Regulatory Cascade Modulates Tissue Metalloproteinase Inhibitor-1 and Matrix Metalloprotease Expression in Hepatic Stellate Cells and Promotes Resolution of Liver Fibrosis
2005
Basement membrane-like matrix inhibits proliferation and collagen synthesis by activated rat hepatic stellate cells: evidence for matrix-dependent deactivation of stellate cells
2003
Protective and pathogenic functions of macrophage subsets
2011 Standout
Discoidin Domain Receptor 2 Regulates Fibroblast Proliferation and Migration through the Extracellular Matrix in Association with Transcriptional Activation of Matrix Metalloproteinase-2
2002
Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats
2001
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Hepatocellular carcinoma pathogenesis: from genes to environment
2006 Standout
Fibroblasts in cancer
2006 Standout
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
2005
Conditional Ablation of Macrophages Halts Progression of Crescentic Glomerulonephritis
2005
Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis
2003
Novel functions of TIMPs in cell signaling
2006
FXR agonist obeticholic acid reduces hepatic inflammation and fibrosis in a rat model of toxic cirrhosis
2016
Exploring the full spectrum of macrophage activation
2008 Standout
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Mechanisms of Disease: mechanisms of hepatic fibrosis and therapeutic implications
2004
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
2009 Standout
A crucial role for Lyn in TIMP‐1 erythroid cell survival signalling pathway
2013 StandoutNobel
Cytokine functions of TIMP-1
2013
Flying Under the Radar: The Immunobiology of Hepatitis C
2006 StandoutNobel
DDR2 receptor promotes MMP-2–mediated proliferation and invasion by hepatic stellate cells
2001
Apoptosis and angiogenesis: an evolving mechanism for fibrosis
2013
Mechanisms of Organ Injury and Repair by Macrophages
2016
Emerging Concepts in Inflammation and Fibrosis
2002
Mac the knife? Macrophages– the double-edged sword of hepatic fibrosis
2005
Tissue inhibitor of metalloproteinases-1 signalling pathway leading to erythroid cell survival
2003
VEGF Secreted by Hypoxic Müller Cells Induces MMP-2 Expression and Activity in Endothelial Cells to Promote Retinal Neovascularization in Proliferative Diabetic Retinopathy
2013 StandoutNobel
Inhibition of hepatic fibrogenesis by matrix metalloproteinase‐9 mutants in mice
2006
Leptin as a novel profibrogenic cytokine in hepatic stellate cells: mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation
2004
Immunological and molecular aspects of liver fibrosis in chronic hepatitis C virus infection.
2005
How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions*
2000 Standout
Reversal of Liver Fibrosis and Cirrhosis — An Emerging Reality
2004
Wound Healing: A Cellular Perspective
2018 Standout
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Controls of Hair Follicle Cycling
2001 Standout
Diverse functions of matrix metalloproteinases during fibrosis
2014
Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis
2003
Hepatic fibrosis and cirrhosis: The (myo)fibroblastic cell subpopulations involved
2005
Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis
2000
Leptin Increases Tissue Inhibitor of Metalloproteinase I (TIMP-1) Gene Expression by a Specificity Protein 1/Signal Transducer and Activator of Transcription 3 Mechanism
2006
Hypoxia-Inducible Factor 1α Is a Critical Downstream Mediator for Hypoxia-Induced Mitogenic Factor (FIZZ1/RELMα)–Induced Pulmonary Hypertension
2015 StandoutNobel
Inflammation and metabolism in tissue repair and regeneration
2017 StandoutScience
HEPATIC FIBROSIS: Molecular Mechanisms and Drug Targets
2004
Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to Mechanical Loading
2004 Standout
Fast detection of liver fibrosis with collagen-binding single-nanometer iron oxide nanoparticles via T 1 -weighted MRI
2023 StandoutNobel
Integrating mechanisms of pulmonary fibrosis
2011 Standout
Works of Christopher Benyon being referenced
Inhibition of Apoptosis of Activated Hepatic Stellate Cells by Tissue Inhibitor of Metalloproteinase-1 Is Mediated via Effects on Matrix Metalloproteinase Inhibition
2002
Interaction of Neuropeptides with Human Mast Cells
1989
Control of the Tissue Inhibitor of Metalloproteinases–1 Promoter in Culture–Activated Rat Hepatic Stellate Cells: Regulation by Activator Protein–1 Dna Binding Proteins
1999
Elastin accumulation is regulated at the level of degradation by macrophage metalloelastase (MMP-12) during experimental liver fibrosis
2011
Mutation in collagen‐I that confers resistance to the action of collagenase results in failure of recovery from CCl 4 ‐induced liver fibrosis, persistence of activated hepatic stellate cells, and diminished hepatocyte regeneration
2002
Progelatinase A is produced and activated by rat hepatic stellate cells and promotes their proliferation
1999