Standout Papers
Citation Impact
Citing Papers
Complement and microglia mediate early synapse loss in Alzheimer mouse models
2016 StandoutScience
Multiplex Genome Engineering Using CRISPR/Cas Systems
2013 StandoutScience
Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells
2008 StandoutScienceNobel
Protein Delivery Using Cys 2 –His 2 Zinc-Finger Domains
2014
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
ER Tubules Mark Sites of Mitochondrial Division
2011 StandoutScience
Inhibition of NADPH oxidase promotes alternative and anti‐inflammatory microglial activation during neuroinflammation
2011
Four-component protein nanocages designed by programmed symmetry breaking
2024 StandoutNatureNobel
Distinct fibroblast lineages determine dermal architecture in skin development and repair
2013 StandoutNature
Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions
2024 StandoutNobel
Therapeutic effects of glatiramer acetate and grafted CD115+monocytes in a mouse model of Alzheimer’s disease
2015
A new PG13-based packaging cell line for stable production of clinical-grade self-inactivating γ-retroviral vectors using targeted integration
2009
Inflammation in Alzheimer Disease--A Brief Review of the Basic Science and Clinical Literature
2011
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Frataxin deficiency induces Schwann cell inflammation and death
2009
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Pois(s)on – It's a Question of Dose…
2004
Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia
2009
Generation of a packaging cell line for prolonged large‐scale production of high‐titer HIV‐1‐based lentiviral vector
2005
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
Cloning of ascidian homeobox genes provides evidence for a primordial chordate cluster
1995
Detailed comparison of retroviral vectors and promoter configurations for stable and high transgene expression in human induced pluripotent stem cells
2017
Macrophages in the Pathogenesis of Atherosclerosis
2011 Standout
Human Primary Immunodeficiency Diseases
2007
Viral vectors: from virology to transgene expression
2008
Genotoxicity of Retroviral Integration In Hematopoietic Cells
2006
Haematopoietic stem cells require a highly regulated protein synthesis rate
2014 Nature
Tracking genome engineering outcome at individual DNA breakpoints
2011
Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation
2010 StandoutNobel
Virus-mediated gene delivery for human gene therapy
2012
An optimized lentiviral vector system for conditional RNAi and efficient cloning of microRNA embedded short hairpin RNA libraries
2017
Upping the Ante: Recent Advances in Direct Reprogramming
2009
TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease
2008
Mitochondria: In Sickness and in Health
2012 Standout
Systemic inflammatory cells fight off neurodegenerative disease
2010
Immune attack: the role of inflammation in Alzheimer disease
2015 Standout
Mitochondrial dynamics in cell death and neurodegeneration
2010
WNT signalling in the immune system: WNT is spreading its wings
2008
Nanotechnologies in delivery of mRNA therapeutics using nonviral vector-based delivery systems
2017
Protein Transfer Into Human Cells by VSV-G-induced Nanovesicles
2011
Elimination of large tumors in mice by mRNA-encoded bispecific antibodies
2017 StandoutNobel
Parkinson's disease
2015 Standout
A Multicolor Panel of Novel Lentiviral “Gene Ontology” (LeGO) Vectors for Functional Gene Analysis
2008
Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease
2008
A New Generation of Retroviral Producer Cells: Predictable and Stable Virus Production by Flp-Mediated Site-Specific Integration of Retroviral Vectors
2006
Alpharetroviral Vector-mediated Gene Therapy for X-CGD: Functional Correction and Lack of Aberrant Splicing
2012
From endoplasmic-reticulum stress to the inflammatory response
2008 StandoutNature
Viruses and tumours – an update
2004
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
Hematopoietic Stem-Cell Transplantation
2006 Standout
Progress and problems with the use of viral vectors for gene therapy
2003 Standout
Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins
2022
Neutrophils, from Marrow to Microbes
2010 Standout
Development of B-lineage Predominant Lentiviral Vectors for Use in Genetic Therapies for B Cell Disorders
2010
Targeted genome editing in pluripotent stem cells using zinc-finger nucleases
2010
Neuroinflammatory mechanisms in Parkinson's disease: Potential environmental triggers, pathways, and targets for early therapeutic intervention
2007
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
Induced pluripotent stem cell–derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice
2010 StandoutNobel
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
2009
Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases
2012 StandoutNobel
Retrovirus Silencing, Variegation, Extinction, and Memory Are Controlled by a Dynamic Interplay of Multiple Epigenetic Modifications
2004
Meganucleases and Other Tools for Targeted Genome Engineering: Perspectives and Challenges for Gene Therapy
2011
Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes
2016 StandoutNobel
Intracellular amyloid-β in Alzheimer's disease
2007 Standout
Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention
2009
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
2010 StandoutNature
Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
2014 Standout
Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications
2017 StandoutNobel
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
Canine Models of Gene-Modified Hematopoiesis
2009
The cancer genome
2009 StandoutNature
Defining and Assaying RNAi in Mammalian Cells
2005
Mutagenesis and Oncogenesis by Chromosomal Insertion of Gene Transfer Vectors
2006
Gene Therapy for X-Linked Severe Combined Immunodeficiency: Where Do We Stand?
2016
A Stable Producer Cell Line for the Manufacture of a Lentiviral Vector for Gene Therapy of Parkinson's Disease
2010
Quantification and Characterization of Autotransduction in Retroviral Vector Producer Cells
2007
TK.007: A Novel, Codon-Optimized HSVtk(A168H) Mutant for Suicide Gene Therapy
2010
Transduction of Rhesus Macaque Hematopoietic Stem and Progenitor Cells with Avian Sarcoma and Leukosis Virus Vectors
2007
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity
2022 StandoutNobel
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
2023 StandoutNobel
A tragic setback
2002 Nature
Cancer suicide gene therapy with TK.007: superior killing efficiency and bystander effect
2011
Functional Reconstitution of Class II MHC-Restricted T Cell Immunity Mediated by Retroviral Transfer of the αβ TCR Complex
2000
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Targeted and Equally Distributed Delivery of mRNA to Organs with Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers
2023 StandoutNobel
Self-Inactivating Alpharetroviral Vectors with a Split-Packaging Design
2010
TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models
2015
Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors
2008 StandoutScienceNobel
Side effects of retroviral gene transfer into hematopoietic stem cells
2003
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Murine Embryonic Stem Cell-Derived Hepatic Progenitor Cells Engraft in Recipient Livers with Limited Capacity of Liver Tissue Formation
2008
Oncoretrovirus and Lentivirus Vectors Pseudotyped with Lymphocytic Choriomeningitis Virus Glycoprotein: Generation, Concentration, and Broad Host Range
2002
Modeling hepatitis C virus infection using human induced pluripotent stem cells
2012 StandoutNobel
Functional mapping of disease susceptibility loci using cell biology
2006 StandoutNobel
Reprogramming homing endonuclease specificity through computational design and directed evolution
2013 StandoutNobel
B cell–specific lentiviral gene therapy leads to sustained B-cell functional recovery in a murine model of X-linked agammaglobulinemia
2010
Zebrafish hox Clusters and Vertebrate Genome Evolution
1998 StandoutScience
Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus
2014 StandoutNobel
megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering
2013 StandoutNobel
Pulmonary transplantation of macrophage progenitors as effective and long-lasting therapy for hereditary pulmonary alveolar proteinosis
2014
Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers
2021 StandoutNobel
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
Targeting neuroinflammation in Alzheimer’s disease: evidence for NSAIDs and novel therapeutics
2016
Genome-Wide Analysis of Alpharetroviral Integration in Human Hematopoietic Stem/Progenitor Cells
2014
Recombinant messenger RNA technology and its application in cancer immunotherapy, transcript replacement therapies, pluripotent stem cell induction, and beyond
2015
HEK293-Based Production Platform for γ-Retroviral (Self-Inactivating) Vectors: Application for Safe and Efficient Transfer ofCOL7A1cDNA
2014
Innate or Adaptive Immunity? The Example of Natural Killer Cells
2011 StandoutScience
CD28 costimulation and immunoaffinity-based selection efficiently generate primary gene-modified T cells for adoptive immunotherapy
2002
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of Christopher Baum being referenced
Alpharetroviral Self-inactivating Vectors: Long-term Transgene Expression in Murine Hematopoietic Cells and Low Genotoxicity
2012
Modified Lentiviral LTRs Allow Flp Recombinase–mediated Cassette Exchange and In Vivo Tracing of “Factor-free” Induced Pluripotent Stem Cells
2014
Insertional Transformation of Hematopoietic Cells by Self-inactivating Lentiviral and Gammaretroviral Vectors
2009
Avoiding cytotoxicity of transposases by dose-controlled mRNA delivery
2011
Viral and Non-Viral Approaches for Transient Delivery of mRNA and Proteins
2011
Dominant Selection of Hematopoietic Progenitor Cells with Retroviral MDR1 Co-Expression Vectors
1998
Clinical Application of Lentiviral Vectors – Concepts and Practice
2008
A Novel NK-Related Mouse Homeobox Gene: Expression in Central and Peripheral Nervous Structures during Embryonic Development
1994
Generation and genetic modification of induced pluripotent stem cells
2010
Equal potency of gammaretroviral and lentiviral SIN vectors for expression of O6-methylguanine–DNA methyltransferase in hematopoietic cells
2005
Genetic protection of repopulating hematopoietic cells with an improved MDR1‐retrovirus allows administration of intensified chemotherapy following stem cell transplantation in mice
2002
LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia
2006
Retroviral and Transposon-Based Tet-Regulated All-In-One Vectors with Reduced Background Expression and Improved Dynamic Range
2010
Lack of Superinfection Interference in Retroviral Vector Producer Cells
2001
Mutagenesis by retroviral transgene insertion: risk assessment and potential alternatives.
2003
Protein transduction from retroviral Gag precursors
2010
Murine Leukemia Induced by Retroviral Gene Marking
2002 Science
Retroviral Vectors Pseudotyped with Lymphocytic Choriomeningitis Virus
1999
Dose finding with retroviral vectors: correlation of retroviral vector copy numbers in single cells with gene transfer efficiency in a cell population
2003
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia
2011
LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia
2006 Standout