Citation Impact
Citing Papers
The Caenorhabditis elegans vulval morphogenesis gene sqv - 4 encodes a UDP-glucose dehydrogenase that is temporally and spatially regulated
2002 StandoutNobel
UDP-Glucose Dehydrogenase Required for Cardiac Valve Formation in Zebrafish
2001 Science
A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling
2007 StandoutNobel
Trastuzumab as adjuvant systemic therapy for HER2-positive breast cancer
2008
Blockade of Epidermal Growth Factor- or Heregulin-Dependent ErbB2 Activation with the Anti-ErbB2 Monoclonal Antibody 2C4 Has Divergent Downstream Signaling and Growth Effects
2004
Molecular mechanisms underlying ErbB2/HER2 action in breast cancer
2000
ErbB Receptors: Directing Key Signaling Networks Throughout Life
2004
The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system
1998
The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation
2003
The ErbB-2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derived growth factors
1999
Biochemical and Clinical Implications of the ErbB/HER Signaling Network of Growth Factor Receptors
1999
ErbB2 Is Necessary for Induction of Carcinoma Cell Invasion by Erbb Family Receptor Tyrosine Kinases
2000
The Crystal Structure of a Truncated ErbB2 Ectodomain Reveals an Active Conformation, Poised to Interact with Other ErbB Receptors
2003
Changes in ErbB2 (her-2/neu), ErbB3, and ErbB4 during Growth, Differentiation, and Apoptosis of Normal Rat Mammary Epithelial Cells
2000
Toward controlling gene expression at will: Specific regulation of the erbB - 2 / HER - 2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks
1998
Arresting a Transient Receptor Potential (TRP) Channel
2010 StandoutNobel
The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives
1999 StandoutNature
Antitumor activity of HER-2 inhibitors
2004
Biologic and therapeutic role of HER2 in cancer
2003
Her4 and Her2/neu Tyrosine Kinase Domains Dimerize and Activate in a Reconstituted in Vitro System
2009
Bivalence of EGF-like ligands drives the ErbB signaling network
1997
ERBB receptors and cancer: the complexity of targeted inhibitors
2005 Standout
Neuregulins Promote Survival and Growth of Cardiac Myocytes
1998
Evolutionary Analysis of the ErbB Receptor and Ligand Families
2000
Distinct Neural Stem Cells Proliferate in Response to EGF and FGF in the Developing Mouse Telencephalon
1999
Independent β-Arrestin2 and Gq/Protein Kinase Cζ Pathways for ERK Stimulated by Angiotensin Type 1A Receptors in Vascular Smooth Muscle Cells Converge on Transactivation of the Epidermal Growth Factor Receptor
2009 StandoutNobel
Specificity within the EGF family/ErbB receptor family signaling network
1998
Genes that mediate breast cancer metastasis to the brain
2009 StandoutNature
Control of EGF Receptor Signalling: Lessons from Fruitflies
1999
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21
2006 StandoutNature
The discovery of receptor tyrosine kinases: targets for cancer therapy
2004
Heparin‐binding epidermal growth factor‐like growth factor as a novel targeting molecule for cancer therapy
2006
Oncogenic kinase signalling
2001 StandoutNature
A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor
1998
ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
1997
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
Tumor Necrosis Factor-α-converting Enzyme Is Required for Cleavage of erbB4/HER4
2000
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Wound repair and regeneration
2008 StandoutNature
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
Differential endocytic routing of homo- and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers
1998
Analysis of HER2 and HER4 in Human Myocardium to Clarify the Cardiotoxicity of Trastuzumab (Herceptin™)
2003
Radiotherapy plus Cetuximab for Squamous-Cell Carcinoma of the Head and Neck
2006 Standout
Severe neuropathies in mice with targeted mutations in the ErbB3 receptor
1997 Nature
Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling.
1998 StandoutNobel
Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer
2004 Standout
Mice Lacking α-Calcitonin Gene-Related Peptide Exhibit Normal Cardiovascular Regulation and Neuromuscular Development
1999
Pathogenic poxviruses reveal viral strategies to exploit the ErbB signaling network
1998
Lives of a Heart Cell: Tracing the Origins of Cardiac Progenitors
2008
EGF–ERBB signalling: towards the systems level
2006 Standout
ESDN, a Novel Neuropilin-like Membrane Protein Cloned from Vascular Cells with the Longest Secretory Signal Sequence among Eukaryotes, Is Up-regulated after Vascular Injury
2001 StandoutNobel
Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor
1995 Nature
Rescue of the Cardiac Defect in ErbB2 Mutant Mice Reveals Essential Roles of ErbB2 in Peripheral Nervous System Development
1999
A genetic blueprint for cardiac development
2000 Nature
Feedback inhibition by RALT controls signal output by the ErbB network
2003
ErbB2 is essential in the prevention of dilated cardiomyopathy
2002
Characterization of a naturally occurring ErbB4 isoform that does not bind or activate phosphatidyl inositol 3-kinase
1999
Roles of JUMONJI in mouse embryonic development
2004
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Anticancer drugs and cardiotoxicity: Insights and perspectives in the era of targeted therapy
2009
Multipotent Flk-1+ Cardiovascular Progenitor Cells Give Rise to the Cardiomyocyte, Endothelial, and Vascular Smooth Muscle Lineages
2006
Signals Transduced by Ca2+/Calcineurin and NFATc3/c4 Pattern the Developing Vasculature
2001
Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases
1997 Nature
Epiregulin Is a Potent Pan-ErbB Ligand That Preferentially Activates Heterodimeric Receptor Complexes
1998
Vascular-specific growth factors and blood vessel formation
2000 StandoutNature
NEW EMBO MEMBERS' REVIEW: The ErbB signaling network: receptor heterodimerization in development and cancer
2000 Standout
Stem Cell-derived Neural Stem/Progenitor Cell Supporting Factor Is an Autocrine/Paracrine Survival Factor for Adult Neural Stem/Progenitor Cells
2003 StandoutNobel
Mechanisms of angiogenesis
1997 StandoutNature
Patterning the vertebrate heart
2002
Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis
1996 Standout
The transcription factor NF-ATc is essential for cardiac valve formation
1998 Nature
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
2003 StandoutNature
From catalytic asymmetric synthesis to the transcriptional regulation of genes: In vivo and in vitro evolution of proteins
2001 StandoutNobel
Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, Angiopoietins, and ephrins in vascular development
1999
β-Arrestin–mediated β1-adrenergic receptor transactivation of the EGFR confers cardioprotection
2007 StandoutNobel
Defects in Sensory and Autonomic Ganglia and Absence of Locus Coeruleus in Mice Deficient for the Homeobox Gene Phox2a
1997
c-Src, Receptor Tyrosine Kinases, and Human Cancer
1999
Neuregulins: functions, forms, and signaling strategies
2003
Ligands for ErbB-family receptors encoded by a neuregulin-like gene
1997 NatureNobel
Are Complex Behaviors Specified by Dedicated Regulatory Genes? Reasoning from Drosophila
2001 StandoutNobel
Genes that mediate breast cancer metastasis to lung
2005 StandoutNature
Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis
2003 StandoutNature
Neuregulin1/ErbB4 Signaling Induces Cardiomyocyte Proliferation and Repair of Heart Injury
2009
Inhibition of Spontaneous β2-Adrenergic Activation Rescues β1-Adrenergic Contractile Response in Cardiomyocytes Overexpressing β2-Adrenoceptor
2000 StandoutNobel
Receptor Activity-modifying Proteins 2 and 3 Have Distinct Physiological Functions from Embryogenesis to Old Age
2007 StandoutNobel
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation
2010 StandoutNature
The cancer genome
2009 StandoutNature
Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4
1998 Standout
Neuregulin-4: a novel growth factor that acts through the ErbB-4 receptor tyrosine kinase
1999
Neuregulin-3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4
1997
Embryonic development is disrupted by modest increases in vascular endothelial growth factor gene expression
2000
Protein–protein interactions define specificity in signal transduction
2000
Directed and Systematic Differentiation of Cardiovascular Cells From Mouse Induced Pluripotent Stem Cells
2008 StandoutNobel
The SQV-1 UDP-glucuronic acid decarboxylase and the SQV-7 nucleotide-sugar transporter may act in the Golgi apparatus to affect Caenorhabditis elegans vulval morphogenesis and embryonic development
2002 StandoutNobel
Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis
1997 StandoutScience
Cardiac Dysfunction in the Trastuzumab Clinical Trials Experience
2002 Standout
Maintenance of Acetylcholine Receptor Number by Neuregulins at the Neuromuscular Junction in Vivo
1997 Science
Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene
2001 StandoutNobel
Neural Science
2000 StandoutNobel
Transient Regenerative Potential of the Neonatal Mouse Heart
2011 StandoutScience
A Pictet-Spengler ligation for protein chemical modification
2012 StandoutNobel
Characterization of a Neuregulin-Related Gene, Don-1, That Is Highly Expressed in Restricted Regions of the Cerebellum and Hippocampus
1997
Cancer Genome Landscapes
2013 StandoutScience
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
Epiregulin Is Not Essential for Development of Intestinal Tumors but Is Required for Protection from Intestinal Damage
2004
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 StandoutNobel
Mutation of the Sry-related Sox10 gene in Dominant megacolon , a mouse model for human Hirschsprung disease
1998
ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2- and heregulin-deficient mice
1997
Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function
2003
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
Cardiac transgenic and gene-targeted mice as models of cardiac hypertrophy and failure: A problem of (new) riches
1998
Heparin-binding EGF-like growth factor accelerates keratinocyte migration and skin wound healing
2005
Evidence for Cardiomyocyte Renewal in Humans
2009 StandoutScience
Works of Christopher B. Hauser being referenced
Requirement for neuregulin receptor erbB2 in neural and cardiac development
1995 Nature