Standout Papers

Experimental and computational approaches to estimate solubility and permeability... 1997 2026 2006 2016 14.0k
  1. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1 (2001)
    Christopher A. Lipinski, Franco Lombardo et al. Advanced Drug Delivery Reviews
  2. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings (1997)
    Christopher A. Lipinski, Franco Lombardo et al. Advanced Drug Delivery Reviews
  3. Lead- and drug-like compounds: the rule-of-five revolution (2004)
    Christopher A. Lipinski Drug Discovery Today Technologies
  4. Drug-like properties and the causes of poor solubility and poor permeability (2000)
    Christopher A. Lipinski Journal of Pharmacological and Toxicological Methods
  5. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings (2012)
    Christopher A. Lipinski, Franco Lombardo et al. Advanced Drug Delivery Reviews
  6. Navigating chemical space for biology and medicine (2004)
    Christopher A. Lipinski, Andrew L. Hopkins Nature
  7. Rule of five in 2015 and beyond: Target and ligand structural limitations, ligand chemistry structure and drug discovery project decisions (2016)
    Christopher A. Lipinski Advanced Drug Delivery Reviews

Immediate Impact

6 by Nobel laureates 16 from Science/Nature 164 standout
Sub-graph 1 of 20

Citing Papers

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Works of Christopher A. Lipinski being referenced

Navigating chemical space for biology and medicine
2004 StandoutNature
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1
2001 Standout

Author Peers

Author Last Decade Papers Cites
Christopher A. Lipinski 15208 11004 11151 70 34.2k
Franco Lombardo 11923 8595 9210 40 27.2k
Beryl W. Dominy 11325 8355 8100 17 24.9k
Garrett M. Morris 20439 9017 9273 120 37.0k
Thomas A. Halgren 17226 8061 9008 64 32.7k
David S. Goodsell 26708 10280 10062 223 44.7k
Richard K. Belew 15168 7373 6796 48 28.6k
Ruth Huey 18085 8558 7990 20 32.8k
Corwin Hansch 9380 13018 6823 334 32.5k
Michel F. Sanner 13452 5727 5840 45 24.2k
Brian K. Shoichet 23888 5056 15092 257 35.2k

All Works

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2026