Citation Impact
Citing Papers
Isolated 17,20-Lyase Deficiency due to the Cytochrome b5 Mutation W27X
2010
The Common P450 Oxidoreductase Variant A503V Is Not a Modifier Gene for 21-Hydroxylase Deficiency
2008
Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54
2003 Standout
Nonclassic Lipoid Congenital Adrenal Hyperplasia Masquerading as Familial Glucocorticoid Deficiency
2009
Extraadrenal 21-Hydroxylation by CYP2C19 and CYP3A4: Effect on 21-Hydroxylase Deficiency
2008
Ferroptosis: molecular mechanisms and health implications
2020 Standout
Biology of FGFRL1, the fifth fibroblast growth factor receptor
2010
Severe loss‐of‐function mutations in the adrenocorticotropin receptor (ACTHR, MC2R) can be found in patients diagnosed with salt‐losing adrenal hypoplasia
2006
Inherited ACTH insensitivity illuminates the mechanisms of ACTH action
2005
Global Disorders of Sex Development Update since 2006: Perceptions, Approach and Care
2016
Complex assembly on the human CYP17 promoter
2008
Growth Hormone Treatment of Non–Growth Hormone-Deficient Growth Disorders
2007
Fetal Programming of Adrenal Androgen Excess: Lessons from a Nonhuman Primate Model of Polycystic Ovary Syndrome
2008
PlantCARE, a database of plant cis-acting regulatory elements and a portal to tools for in silico analysis of promoter sequences
2002 Standout
Estrogen receptors and human disease
2006 Standout
Hyponatremia Treatment Guidelines 2007: Expert Panel Recommendations
2007 Standout
Inhibition of AP-1 by SARI negatively regulates transformation progression mediated by CCN1
2010 Standout
RAB23 Mutations in Carpenter Syndrome Imply an Unexpected Role for Hedgehog Signaling in Cranial-Suture Development and Obesity
2007
Epigenetics meets endocrinology
2010
Neonatal screening for congenital adrenal hyperplasia
2009
Recognizing rare disorders: aromatase deficiency
2007
Prenatal exposure to fluconazole: An identifiable dysmorphic phenotype
2005
The human fetal adrenal cortex and the window of sexual differentiation
2006
A 52‐kb deletion in the SOST‐MEOX1 intergenic region on 17q12‐q21 is associated with van Buchem disease in the Dutch population
2002 StandoutNobel
Functional Selectivity and Classical Concepts of Quantitative Pharmacology
2006 StandoutNobel
Genetic basis of potential therapeutic strategies for craniosynostosis
2010
Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment
2018 Standout
P450 Oxidoreductase Expressed in Rat Chondrocytes Modulates Chondrogenesis via Cholesterol- and Indian Hedgehog-Dependent Mechanisms
2009
Hallmarks of aging: An expanding universe
2023 Standout
Defects of cholesterol biosynthesis
2006
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
2022 Standout
Cytochrome P450 Oxidoreductase Deficiency in Three Patients Initially Regarded as Having 21-Hydroxylase Deficiency and/or Aromatase Deficiency: Diagnostic Value of Urine Steroid Hormone Analysis
2006
Cytochrome P450 oxidoreductase contributes tophospholipid peroxidation in ferroptosis
2020
Single-cell analysis of somatic mutations in human bronchial epithelial cells in relation to aging and smoking
2022
Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro
2010
Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline
2016 Standout
Rab GTPases as coordinators of vesicle traffic
2009 Standout
Biochemical and Physiological Aspects of Endogenous Androgens
2009
Adrenal toxicology: a strategy for assessment of functional toxicity to the adrenal cortex and steroidogenesis
2007
The new bone biology: Pathologic, molecular, and clinical correlates
2006
The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
2016 Standout
The backdoor pathway to dihydrotestosterone
2004
Substrate-specific modulation of CYP3A4 activity by genetic variants of cytochrome P450 oxidoreductase
2010
Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
2008 StandoutNature
Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline
2013 Standout
5α-reduced C21 steroids are substrates for human cytochrome P450c17
2003
Androgen synthesis in adrenarche
2008
From Krebs to clinic: glutamine metabolism to cancer therapy
2016 Standout
TRANSFAC: an integrated system for gene expression regulation
2000
Alterations of folliculogenesis in women with polycystic ovary syndrome
2011
An automated method for finding molecular complexes in large protein interaction networks
2003 Standout
Steroid 5α-reductase 1 promotes 5α-androstane-3α,17β-diol synthesis in immature mouse testes by two pathways
2004
Monogenic Disorders of Puberty
2002
Congenital adrenal hyperplasia caused by mutant P450 oxidoreductase and human androgen synthesis: analytical study
2004
Genetic Causes of Human Reproductive Disease
2002
Epigenetics of endometriosis
2009
The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication
2020 Standout
Broadening horizons: the role of ferroptosis in cancer
2021 Standout
Polymorphisms in the Sclerosteosis/van Buchem Disease Gene (SOST) Region Are Associated with Bone-Mineral Density in Elderly Whites
2004 StandoutNobel
Transcriptional Regulation of Adrenocortical Steroidogenic Gene Expression
2007
Consensus Statement on Management of Intersex Disorders
2006 Standout
The FGFRL1 Receptor Is Shed from Cell Membranes, Binds Fibroblast Growth Factors (FGFs), and Antagonizes FGF Signaling in Xenopus Embryos
2009
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
2008 Standout
Human ovarian theca cells in culture
2006
Oxidative Damage and Antioxidant Defense in Ferroptosis
2020
Targeting ferroptosis as a vulnerability in cancer
2022 Standout
Nephrogenic Syndrome of Inappropriate Antidiuresis
2005
Zika Virus and Birth Defects — Reviewing the Evidence for Causality
2016 Standout
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
Modeling the structure of the StART domains of MLN64 and StAR proteins in complex with cholesterol
2006
Nonclassic Congenital Lipoid Adrenal Hyperplasia: A New Disorder of the Steroidogenic Acute Regulatory Protein with Very Late Presentation and Normal Male Genitalia
2006
Coccidioidomycosis During Pregnancy: A Review and Recommendations for Management
2011
Estrogen and adiposity—Utilizing models of aromatase deficiency to explore the relationship
2007
Determination of human teratogenicity by the astute clinician method: Review of illustrative agents and a proposal of guidelines
2008
Polycystic ovary syndrome
2016 Standout
Predisposing Factors for Adrenal Insufficiency
2009
Fibroblast Growth Factor Receptor Like-1 (FGFRL1) Interacts with SHP-1 Phosphatase at Insulin Secretory Granules and Induces Beta-cell ERK1/2 Protein Activation
2013
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
2013 Standout
CYP17 Mutation E305G Causes Isolated 17,20-Lyase Deficiency by Selectively Altering Substrate Binding
2003
Pendred's Syndrome and Genetic Defects in Thyroid Hormone Synthesis
2000
Physiological Estrogen Replacement Therapy for Puberty Induction in Girls: A Clinical Observational Study
2014
Genetic and Clinical Features of P450 Oxidoreductase Deficiency
2008
The Diagnosis of Polycystic Ovary Syndrome during Adolescence
2015 Standout
3β-Hydroxysterol Δ7-reductase and the Smith–Lemli–Opitz syndrome
2004
Regulation of 17,20 Lyase Activity by Cytochrome b5 and by Serine Phosphorylation of P450c17
2005
The murine Fgfrl1 receptor is essential for the development of the metanephric kidney
2009
Targeted Disruption of the Intracellular Domain of Receptor FgfrL1 in Mice
2014
TRANSFAC(R): transcriptional regulation, from patterns to profiles
2003 Standout
Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1
2020
Prenatal diagnosis of P450 oxidoreductase deficiency (ORD): A disorder causing low pregnancy estriol, maternal and fetal virilization, and the Antley–Bixler syndrome phenotype
2004
Hormonal regulation of longevity in mammals
2007
Pharmacogenetics of P450 oxidoreductase: effect of sequence variants on activities of CYP1A2 and CYP2C19
2008
The Fibroblast Growth Factor signaling pathway
2015 Standout
Clinical, Genetic, and Enzymatic Characterization of P450 Oxidoreductase Deficiency in Four Patients
2009
Molecular Biology of the 3β-Hydroxysteroid Dehydrogenase/Δ5-Δ4 Isomerase Gene Family
2005
Regulation of Cytochrome b5 Gene Transcription by Sp3, GATA-6, and Steroidogenic Factor 1 in Human Adrenal NCI-H295A Cells
2005
Homozygous Mutation G539R in the Gene for P450 Oxidoreductase in a Family Previously Diagnosed as Having 17,20-Lyase Deficiency
2008
Pathogenesis and pathophysiology of endometriosis
2012 Standout
P450c17 Deficiency: Clinical and Molecular Characterization of Six Patients
2006
Chronopharmacology: New Insights and Therapeutic Implications
2013
EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals
2015 Standout
Increased Expression of Genes Converting Adrenal Androgens to Testosterone in Androgen-Independent Prostate Cancer
2006 Standout
Impact of Estrogen Replacement Therapy in a Male with Congenital Aromatase Deficiency Caused by a Novel Mutation in the CYP19 Gene
2002
2016 Infectious Diseases Society of America (IDSA) Clinical Practice Guideline for the Treatment of Coccidioidomycosis
2016 Standout
Cytochrome P450 Oxidoreductase Gene Mutations and Antley-Bixler Syndrome with Abnormal Genitalia and/or Impaired Steroidogenesis: Molecular and Clinical Studies in 10 Patients
2005
Identification and transcriptome analysis of erythroblastic island macrophages
2019 StandoutNobel
Apparent Manifesting Heterozygosity in P450 Oxidoreductase Deficiency and Its Effect on Coexisting 21-Hydroxylase Deficiency
2007
LBP Proteins Modulate SF1-Independent Expression of P450scc in Human Placental JEG-3 Cells
2004
Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement
2009 Standout
Molecular Basis of Combined Pituitary Hormone Deficiencies
2002
Cytochrome P450 reductase (POR) as a ferroptosis fuel
2021
Cholesterol Metabolism: the Main Pathway Acting Downstream of Cytochrome P450 Oxidoreductase in Skeletal Development of the Limb
2009
Determination of Glutamate Dehydrogenase Activity and Its Kinetics in Mouse Tissues using Metabolic Mapping (Quantitative Enzyme Histochemistry)
2014
Minireview: Regulation of Steroidogenesis by Electron Transfer
2005
Genetics of P450 oxidoreductase: Sequence variation in 842 individuals of four ethnicities and activities of 15 missense mutations
2008
Sexual and Gender Minority Health: What We Know and What Needs to Be Done
2008 Standout
Physiological and Molecular Basis of Thyroid Hormone Action
2001 Standout
Multiple congenital malformations of Wolf-Hirschhorn syndrome are recapitulated inFgfrl1null mice
2009
Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency: An Endocrine Society* Clinical Practice Guideline
2018
Genetic Causes of Human Reproductive Disease
2002
The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders
2011 Standout
Sampling and energy evaluation challenges in ligand binding protein design
2017 StandoutNobel
Gata4 and Sp1 regulate expression of the erythropoietin receptor in cardiomyocytes
2010
Adverse Health Consequences of Performance-Enhancing Drugs: An Endocrine Society Scientific Statement
2013 Standout
Human Cytochrome b5 Requires Residues E48 and E49 to Stimulate the 17,20-Lyase Activity of Cytochrome P450c17
2005
Clinical, Genetic, and Functional Characterization of Four Patients Carrying Partial Loss-of-Function Mutations in the Steroidogenic Acute Regulatory Protein (StAR)
2010
Circadian Clock, Cancer, and Chemotherapy
2014 StandoutNobel
The Metabolic Syndrome
2008 Standout
Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society* Clinical Practice Guideline
2017 Standout
Insulin Resistance and the Polycystic Ovary Syndrome Revisited: An Update on Mechanisms and Implications
2012 Standout
Epithelioid Glioblastomas and Anaplastic Epithelioid Pleomorphic Xanthoastrocytomas—Same Entity or First Cousins?
2015
Pathways Leading to Phosphorylation of P450c17 and to the Posttranslational Regulation of Androgen Biosynthesis
2008
Protein Glycoengineering Enabled by the Versatile Synthesis of Aminooxy Glycans and the Genetically Encoded Aldehyde Tag
2011 StandoutNobel
Metabolomics for Investigating Physiological and Pathophysiological Processes
2019
The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited
2016
Extending Healthy Life Span—From Yeast to Humans
2010 StandoutScience
Urine Steroid Hormone Profile Analysis in Cytochrome P450 Oxidoreductase Deficiency: Implication for the Backdoor Pathway to Dihydrotestosterone
2006
MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights
2021 Standout
Works of Christa E. Flück being referenced
P450 Oxidoreductase Deficiency – A New Form of Congenital Adrenal Hyperplasia
2008
Diversity and Function of Mutations in P450 Oxidoreductase in Patients with Antley-Bixler Syndrome and Disordered Steroidogenesis
2005
Pioglitazone Inhibits Androgen Production in NCI-H295R Cells by Regulating Gene Expression of CYP17 and HSD3B2
2006
Restoration of mutant cytochrome P450 reductase activity by external flavin
2010
Modulation of Human CYP19A1 Activity by Mutant NADPH P450 Oxidoreductase
2007
P450 oxidoreductase deficiency: a new form of congenital adrenal hyperplasia
2006
The 17, 20-Lyase Activity of Cytochrome P450c17 from Human Fetal Testis Favors the Δ5Steroidogenic Pathway
2003
NADPH P450 oxidoreductase: Structure, function, and pathology of diseases
2013
Acute Encephalopathy with Unilateral Cortical-Subcortical Lesions in Two Unrelated Kindreds Treated with Glucocorticoids Prenatally for Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency: Established Facts and Novel Insight
2013
Steroidogenesis of the testis – new genes and pathways
2014
Characterization of the first FGFRL1 mutation identified in a craniosynostosis patient
2008
Why Boys Will Be Boys: Two Pathways of Fetal Testicular Androgen Biosynthesis Are Needed for Male Sexual Differentiation
2011
Modeling of human P450 oxidoreductase structure by in silico mutagenesis and MD simulation
2009
Mutant P450 oxidoreductase causes disordered steroidogenesis with and without Antley-Bixler syndrome
2004
Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis
2015
Impact of Estrogen Replacement throughout Childhood on Growth, Pituitary-Gonadal Axis and Bone in a 46,XX Patient with CYP19A1 Deficiency
2012
Role of DNA methylation in the tissue-specific expression of the CYP17A1 gene for steroidogenesis in rodents
2009
Adrenal gland development and defects
2008
NADPH–Cytochrome P450 Oxidoreductase: Roles in Physiology, Pharmacology, and Toxicology
2012
Butyrate Increases Intracellular Calcium Levels and Enhances Growth Hormone Release from Rat Anterior Pituitary Cells via the G-Protein-Coupled Receptors GPR41 and 43
2014
A Novel Mutation L260P of the Steroidogenic Acute Regulatory Protein Gene in Three Unrelated Patients of Swiss Ancestry with Congenital Lipoid Adrenal Hyperplasia
2005
Effects of Anticonvulsants on Human P450c17 (17α‐Hydroxylase/17,20 Lyase) and 3β‐Hydroxysteroid Dehydrogenase Type 2
2005
“Hot Spot” in the PROP1 Gene Responsible for Combined Pituitary Hormone Deficiency1
1999
Aromatase Deficiency Caused by a Novel P450arom Gene Mutation: Impact of Absent Estrogen Production on Serum Gonadotropin Concentration in a Boy1
1999
Phenotypic Variability in Familial Combined Pituitary Hormone Deficiency Caused by a PROP1 Gene Mutation Resulting in the Substitution of Arg→Cys at Codon 120 (R120C)1
1998
Clinical and Biochemical Consequences of P450 Oxidoreductase Deficiency
2010
SNP Array Profiling of Childhood Adrenocortical Tumors Reveals Distinct Pathways of Tumorigenesis and Highlights Candidate Driver Genes
2012
Short Stature Caused by a Biologically Inactive Mutant Growth Hormone (GH-C53S)
2005
GATA-4 and GATA-6 Modulate Tissue-Specific Transcription of the Human Gene for P450c17 by Direct Interaction with Sp1
2004
Clinical, Genetic, and Functional Characterization of Adrenocorticotropin Receptor Mutations Using a Novel Receptor Assay
2002