Citation Impact
Citing Papers
Features, Evaluation and Treatment Coronavirus (COVID-19)
2020 Standout
QT interval prolongation related to psychoactive drug treatment: a comparison of monotherapy versus polytherapy
2005
Impact of sex and gender on COVID-19 outcomes in Europe
2020
The hERG potassium channel and hERG screening for drug-induced torsades de pointes
2008
A human ether-á-go-go-related (hERG) ion channel atomistic model generated by long supercomputer molecular dynamics simulations and its use in predicting drug cardiotoxicity
2014 StandoutNobel
The association of serum testosterone levels and ventricular repolarization
2009
The influence of drug-like concepts on decision-making in medicinal chemistry
2007 Standout
Strategies to reduce the risk of drug‐induced QT interval prolongation: a pharmaceutical company perspective
2008
Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework
2014 Standout
Collation, assessment and analysis of literature in vitro data on hERG receptor blocking potency for subsequent modeling of drugs' cardiotoxic properties
2008
The Generation R Study: design and cohort update 2010
2010 Standout
Epidemiology of symptomatic drug-induced long QT syndrome and torsade de pointes in Germany
2013
A structure-based computational workflow to predict liability and binding modes of small molecules to hERG
2020 StandoutNobel
Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG
2012
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Sex and gender: modifiers of health, disease, and medicine
2020 Standout
Therapeutic implications of the gender-specific aspects of cardiovascular disease
2006
Microfluidic organs-on-chips
2014 Standout
In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes
2009 StandoutNobel
Heart repair by reprogramming non-myocytes with cardiac transcription factors
2012 Nature
Analysis of Pharmacology Data and the Prediction of Adverse Drug Reactions and Off‐Target Effects from Chemical Structure
2007
An introduction to QT interval prolongation and non‐clinical approaches to assessing and reducing risk
2010
Estimating the Risk of Drug-Induced Proarrhythmia Using Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes
2011
The ChEMBL database in 2017
2016 Standout
Relating protein pharmacology by ligand chemistry
2007 Standout
Toxicology for the twenty-first century
2009 StandoutNature
Assessing the proarrhythmic potential of drugs: Current status of models and surrogate parameters of torsades de pointes arrhythmias
2006
Acquired QT interval prolongation and HERG: implications for drug discovery and development
2004
An analysis of the attrition of drug candidates from four major pharmaceutical companies
2015 Standout
Fluorine in medicinal chemistry
2007 Standout
Engineering Adolescence
2014 Standout
pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures
2015 Standout
A critical assessment of modeling safety-related drug attrition
2013
Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus
2016 Standout
Future of ToxicologyMechanisms of Toxicity and Drug Safety: Where Do We Go from Here?
2006
Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment
2013 Standout
2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death
2015 Standout
Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
2011 StandoutNobel
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Applications of Fluorine in Medicinal Chemistry
2015 Standout
Works of Chris Pollard being referenced
The application of in vitro methods to safety pharmacology
2002
Nonclinical proarrhythmia models: Predicting Torsades de Pointes
2005
IKs restricts excessive beat-to-beat variability of repolarization during beta-adrenergic receptor stimulation
2009
A framework to assess the translation of safety pharmacology data to humans
2009
Evidence for gender differences in electrophysiological properties of canine Purkinje fibres
2004
Sex differences in ventricular repolarization: from cardiac electrophysiology to Torsades de Pointes
2004
Validation of a voltage-sensitive dye (di-4-ANEPPS)-based method for assessing drug-induced delayed repolarisation in Beagle dog left ventricular midmyocardial myocytes
2009
Comparative Pharmacology of Guinea Pig Cardiac Myocyte and Cloned hERG (IKr) Channel
2004
Dog left ventricular midmyocardial myocytes for assessment of drug‐induced delayed repolarization: short‐term variability and proarrhythmic potential
2009
Impact and prevalence of safety pharmacology-related toxicities throughout the pharmaceutical life cycle
2010