Citation Impact
Citing Papers
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
High‐Throughput Quality Control Assay for the Solid‐Phase Synthesis of DNA‐Encoded Libraries of Macrocycles**
2021
Property‐Driven Development of Passively Permeable Macrocyclic Scaffolds Using Heterocycles**
2022
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
The role of artificial intelligence in healthcare: a structured literature review
2021 Standout
Design and synthesis of ansamycin antibiotics
2008
Diterpenoids from Isodon species and their biological activities
2006 Standout
Light–induced disassembly of self-assembled vesicle-capped nanotubes observed in real time
2011 StandoutNobel
Enzymatic catalysis of the Diels–Alder reaction in the biosynthesis of natural products
2004
Synthesis of (−)‐Okilactomycin by a Prins‐Type Fragment‐Assembly Strategy
2011
Glucagon-Like Peptide-1 and Its Class B G Protein–Coupled Receptors: A Long March to Therapeutic Successes
2016
MC4R Agonists: Structural Overview on Antiobesity Therapeutics
2018 StandoutNobel
Marine natural products
1990 Standout
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
The Pictet–Spengler Reaction in Nature and in Organic Chemistry
2011 Standout
Green synthesis of nitriles using non-noble metal oxides-based nanocatalysts
2014
mRNA display: from basic principles to macrocycle drug discovery
2013 Nobel
Recent advances in bacterial topoisomerase inhibitors
2008
Rescue of Degradation‐Prone Mutants of the FK506‐Rapamycin Binding (FRB) Protein with Chemical Ligands
2007 StandoutNobel
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Drug repurposing: progress, challenges and recommendations
2018 Standout
New paradigms in GPCR drug discovery
2015
PROTAC targeted protein degraders: the past is prologue
2022 Standout
Quantitative measurement of cytosolic penetration using the chloroalkane penetration assay
2020
Late‐Stage Peptide Diversification by Bioorthogonal Catalytic CH Arylation at 23 °C in H2O
2015
DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs
2010 Standout
The Organocatalytic Asymmetric Prins Cyclization
2015 StandoutNobel
Mechanism of Quinolone Action and Resistance
2014 Standout
Structures of G protein-coupled receptors reveal new opportunities for drug discovery
2015
Chemical Approaches to Controlling Intracellular Protein Degradation
2004
Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates
2014
Die organokatalytische asymmetrische Prins‐Cyclisierung
2015 StandoutNobel
AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease
2023 Standout
Orally Absorbed Cyclic Peptides
2017
Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed Biomolecules Synthesis
2008 Standout
Cross‐Coupling of Heteroarenes by CH Functionalization: Recent Progress towards Direct Arylation and Heteroarylation Reactions Involving Heteroarenes Containing One Heteroatom
2014
3d Transition Metals for C–H Activation
2018 Standout
Concepts of Artificial Intelligence for Computer-Assisted Drug Discovery
2019
Artificial intelligence in drug discovery and development
2020 Standout
The emerging role of computational design in peptide macrocycle drug discovery
2020
Emerging Methods and Design Principles for Cell‐Penetrant Peptides
2018
Total Synthesis of Abyssomicin C, Atrop-abyssomicin C, and Abyssomicin D: Implications for Natural Origins of Atrop-abyssomicin C
2006
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Mapping the Efficiency and Physicochemical Trajectories of Successful Optimizations
2018
1,1,3,3‐Tetratriflylpropene (TTP): A Strong, Allylic C–H Acid for Brønsted and Lewis Acid Catalysis
2016 StandoutNobel
Highly enantio- and diastereoselective boron aldol reactions of α-heterosubstituted thioacetates with aldehydes and silyl imines
1997
A Stereocontrolled Synthesis of δ-trans-Tocotrienoloic Acid
2005
Oxidative Coupling between Two Hydrocarbons: An Update of Recent C–H Functionalizations
2015 Standout
The Current State of Peptide Drug Discovery: Back to the Future?
2017
Transition Metal‐Catalyzed CH Activation of Indoles
2015
A General Catalytic Asymmetric Prins Cyclization
2016 StandoutNobel
Metal Catalysts for Heterogeneous Catalysis: From Single Atoms to Nanoclusters and Nanoparticles
2018 Standout
Design and Development of a Cyclic Decapeptide Scaffold with Suitable Properties for Bioavailability and Oral Exposure
2016
Total Synthesis of Herbimycin A
2003
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
2020 Standout
Macrocyclic Peptides as Drug Candidates: Recent Progress and Remaining Challenges
2019
Melanocortin-4 Receptor Modulators for the Treatment of Obesity: a Patent Analysis (2008–2014)
2015
Mild metal-catalyzed C–H activation: examples and concepts
2016 Standout
Allostery and Biased Agonism at Class B G Protein-Coupled Receptors
2016
BODIPY Peptide Labeling by Late‐Stage C(sp3)−H Activation
2018
Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore
2010 Standout
Synthesis of (−)‐Okilactomycin by a Prins‐Type Fragment‐Assembly Strategy
2011
General Approach for the Synthesis of Sarpagine Indole Alkaloids. Enantiospecific Total Synthesis of (+)-Vellosimine, (+)-Normacusine B, (−)-Alkaloid Q3, (−)-Panarine, (+)-Na-Methylvellosimine, and (+)-Na-Methyl-16-epipericyclivine
2003
Catalytic Macrocyclization Strategies Using Continuous Flow: Formal Total Synthesis of Ivorenolide A
2016
Understanding Cell Penetration of Cyclic Peptides
2019
Antimicrobial Resistance in Neisseria gonorrhoeae in the 21st Century: Past, Evolution, and Future
2014 Standout
Lewis Base Activation of Lewis Acids: Catalytic, Enantioselective Addition of Glycolate-Derived Silyl Ketene Acetals to Aldehydes
2008
Palladium-Catalyzed Transformations of Alkyl C–H Bonds
2016 Standout
Site-Selective C(sp3)–H Functionalization of Di-, Tri-, and Tetrapeptides at the N-Terminus
2014
Transition Metal-Catalyzed Organometallic Reactions that Have Revolutionized Organic Synthesis
2007 StandoutNobel
Computational design of mixed chirality peptide macrocycles with internal symmetry
2020 StandoutNobel
Use of Gyrase Resistance Mutants To Guide Selection of 8-Methoxy-Quinazoline-2,4-Diones
2008
Peptidic Macrocycles - Conformational Sampling and Thermodynamic Characterization
2018
Straightforward Synthesis of α,β-Unsaturated Thioesters via Ruthenium-Catalyzed Olefin Cross-Metathesis with Thioacrylate
2008 StandoutNobel
Macrocycles: lessons from the distant past, recent developments, and future directions
2014
An Enantioselective Synthetic Route toward Second-Generation Light-Driven Rotary Molecular Motors
2010 StandoutNobel
Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1
2021 StandoutNobel
Unified mild reaction conditions for C2-selective Pd-catalysed tryptophan arylation, including tryptophan-containing peptides
2015
RNA Display Methods for the Discovery of Bioactive Macrocycles
2018
General approach for the total synthesis of the sarpagine related indole alkaloids (+)-Na-methyl-16-epipericyclivine, (−)-alkaloid Q3 and (−)-panarine via the asymmetric Pictet–Spengler reaction
2003
Click-Chemistry-Mediated Synthesis of Selective Melanocortin Receptor 4 Agonists
2017 StandoutNobel
Macrolactamization Approaches to Arylomycin Antibiotics Core
2018
ETCM: an encyclopaedia of traditional Chinese medicine
2018 Standout
Dose-dependent quantitative effects of acute fructose administration on hepatic de novo lipogenesis in healthy humans
2018
De Novo Carborane-Containing Macrocyclic Peptides Targeting Human Epidermal Growth Factor Receptor
2019 StandoutNobel
Transition-Metal-Catalyzed Reactions in Heterocyclic Synthesis
2004 Standout
Beyond the Rule of 5: Lessons Learned from AbbVie’s Drugs and Compound Collection
2017
Conformational Effects on the Passive Membrane Permeability of Synthetic Macrocycles
2022
Natural Products as Sources of New Drugs from 1981 to 2014
2016 Standout
Practical Procedures for the Preparation of N-tert-Butyldimethylsilylhydrazones and Their Use in Modified Wolff−Kishner Reductions and in the Synthesis of Vinyl Halides and gem-Dihalides
2004
1,1,3,3‐Tetratriflylpropen (TTP): eine starke, allylische C‐H‐Säure für die Brønsted‐ und Lewis‐Säure‐Katalyse
2016 StandoutNobel
Two Decades under the Influence of the Rule of Five and the Changing Properties of Approved Oral Drugs
2018
Cyclic peptide oral bioavailability: Lessons from the past
2016
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
Catalytic Asymmetric Protonation of Silyl Ketene Imines
2013 StandoutNobel
Total synthesis of (+)-ambruticin S
2003
Conformational Strain of Macrocyclic Peptides in Ligand–Receptor Complexes Based on Advanced Refinement of Bound-State Conformers
2021
Total Synthesis of 10-Isocyano-4-cadinene and Determination of Its Absolute Configuration
2010
Confinement-Controlled, Either syn- or anti-Selective Catalytic Asymmetric Mukaiyama Aldolizations of Propionaldehyde Enolsilanes
2021 StandoutNobel
Catalytic Asymmetric Vinylogous Prins Cyclization: A Highly Diastereo- and Enantioselective Entry to Tetrahydrofurans
2016 StandoutNobel
Metal-Free Multicomponent Syntheses of Pyridines
2014 Standout
Works of Chris Limberakis being referenced
Demonstration of the Innate Electrophilicity of 4-(3-(Benzyloxy)phenyl)-2-(ethylsulfinyl)-6-(trifluoromethyl)pyrimidine (BETP), a Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 Receptor
2013
Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes
2014
Peptidic macrocyclization via palladium-catalyzed chemoselective indole C-2 arylation
2012
A potentiator of orthosteric ligand activity at GLP-1R acts via covalent modification
2014
The synthesis and biological evaluation of novel series of nitrile-containing fluoroquinolones as antibacterial agents
2007
Biaryl-Bridged Macrocyclic Peptides: Conformational Constraint via Carbogenic Fusion of Natural Amino Acid Side Chains
2012
Peptide to Peptoid Substitutions Increase Cell Permeability in Cyclic Hexapeptides
2015
Cyclic Peptide Design Guided by Residual Dipolar Couplings, J-Couplings, and Intramolecular Hydrogen Bond Analysis
2019
Studies on the synthesis of the quartromicins: partial stereochemical assignment of quartromicins A3 and D3 and diastereoselective synthesis of the endo- and exo-spirotetronate subunits
2002
Nonclassical Size Dependence of Permeation Defines Bounds for Passive Adsorption of Large Drug Molecules
2017
A New and Useful Method for the Macrocyclization of Linear Peptides
2012
Comparative pharmacokinetic profile of cyclosporine (CsA) with a decapeptide and a linear analogue
2017
Optimizing PK properties of cyclic peptides: the effect of side chain substitutions on permeability and clearance
2012
Novel approach to the ansamycin antibiotics macbecin I and herbimycin A. A formal total synthesis of (+)-macbecin I
1996
Strategies for ansamycin antibiotics. asymmetric synthesis of the C(3)–C(21) subunit of herbimycin A
1999
Short Hydrophobic Peptides with Cyclic Constraints Are Potent Glucagon-like Peptide-1 Receptor (GLP-1R) Agonists
2015
Macrocyclizations for Medicinal Chemistry: Synthesis of Druglike Macrocycles by High-Concentration Ullmann Coupling
2012
Diastereoselective Synthesis of the endo- and exo-Spirotetronate Subunits of the Quartromicins. The First Enantioselective Diels−Alder Reaction of an Acyclic (Z)-1,3-Diene
2002