Citation Impact
Citing Papers
On the relationship between folding and chemical landscapes in enzyme catalysis
2008 StandoutNobel
Loss of conformational entropy in protein folding calculated using realistic ensembles and its implications for NMR-based calculations
2014 StandoutNobel
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Consistent blind protein structure generation from NMR chemical shift data
2008 StandoutNobel
Origins of coevolution between residues distant in protein 3D structures
2017 StandoutNobel
Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions
2011 StandoutNobel
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Nicastrin Functions as a γ-Secretase-Substrate Receptor
2005 StandoutNobel
Cation–π interactions in ligand recognition and catalysis
2002
Just add water! The effect of water on the specificity of protein-ligand binding sites and its potential application to drug design
1996
The Systemic Amyloidoses
1997 Standout
Electrostatic control of charge separation in bacterial photosynthesis
1990 StandoutNobel
Nature of biological electron transfer
1992 StandoutNature
Structure of the photosynthetic reaction centre from Rhodobacter sphaeroides at 2.65 å resolution: cofactors and protein-cofactor interactions
1994 Nobel
Crystal structure of Thermus aquaticus DNA polymerase
1995 StandoutNatureNobel
Protein backbone angle restraints from searching a database for chemical shift and sequence homology
1999 Standout
Protein dynamics from NMR
1998
Structural and mechanistic insight from high resolution structures of archaeal rhodopsins
2003
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
2011 StandoutNatureNobel
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
2012 StandoutNatureNobel
Microscopic simulation of quantum dynamics and nuclear tunneling in bacterial reaction centers
1989 StandoutNobel
Structure of HIV-1 protease with KNI-272, a tight-binding transition-state analog containing allophenylnorstatine
1995
Crystallographic determination of the structures of human α‐thrombin complexed with BMS‐186282 and BMS‐189090
1996
15N backbone dynamics of the S‐peptide from ribonuclease A in its free and S‐protein bound forms: Toward a site‐specific analysis of entropy changes upon folding
1998
Predicting Drug‐Resistant Mutations of HIV Protease
2007 StandoutNobel
Hydration and DNA Recognition by Homeodomains
1996 StandoutNobel
Recombining the structures of HIV integrase, RuvC and RNase H
1995 StandoutNobel
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Mass spectrometric and thermodynamic studies reveal the role of water molecules in complexes formed between SH2 domains and tyrosyl phosphopeptides
1998
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Primary photochemistry of reaction centers from the photosynthetic purple bacteria
1987
Conformations of immunoglobulin hypervariable regions
1989 StandoutNatureNobel
Adhesion receptors of the immune system
1990 StandoutNature
Interfacial Water as a “Hydration Fingerprint” in the Noncognate Complex of BamHI
2005
Three-Dimensional Structure of Antibodies
1988
Photoswitch inhibitors of α-chymotrypsin—increased substitution and peptidic character in peptidomimetic boronate esters
2006
Illuminating the dark conformational space of macrocycles using dominant rotors
2021
Automated prediction of 15N, 13Cα, 13Cβ and 13C′ chemical shifts in proteins using a density functional database
2001
Interactions with Aromatic Rings in Chemical and Biological Recognition
2003 Standout
Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors
1995
Protein–ligand docking: Current status and future challenges
2006
Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 Å resolution
1992 StandoutNobel
AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
2009 Standout
Evolutionarily conserved networks of residues mediate allosteric communication in proteins
2002
A Noncleavable Retro-Binding Peptide That Spans the Substrate Binding Cleft of Serine Proteases. Atomic Structure of Nazumamide A: Human Thrombin
1996
Quantitative exploration of the molecular origin of the activation of GTPase
2013 StandoutNobel
A kinetic analysis of the primary charge separation in bacterial photosynthesis. Energy gaps and static heterogeneity
1995
Initial electron-transfer in the reaction center from Rhodobacter sphaeroides.
1990
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
2010 StandoutNobel
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
Dynamical Contributions to Enzyme Catalysis: Critical Tests of A Popular Hypothesis
2006 StandoutNobel
Human immunodeficiency virus type 1 proteinase resistance to symmetric cyclic urea inhibitor analogs
1997
Converting structural information into an allosteric-energy-based picture for elongation factor Tu activation by the ribosome
2011 StandoutNobel
Water as an Active Constituent in Cell Biology
2007 Standout
Linkage between dynamics and catalysis in a thermophilic-mesophilic enzyme pair
2004
Structure of the reaction center from Rhodobacter sphaeroides R-26: the cofactors.
1987
Ordered water in macromolecular structure
1994
Multiple Mutations in the Human Immunodeficiency Virus Protease Gene Are Responsible for Decreased Susceptibility to Protease Inhibitors
1995
Thermodynamic Contributions of the Ordered Water Molecule in HIV-1 Protease
2003
Nobel lecture. The photosynthetic reaction centre from the purple bacterium Rhodopseudomonas viridis.
1989 Nobel
The dynamics of the primary event in rhodopsins revisited
1991 StandoutNobel
Synthesis of conformationally-restricted boropeptide thrombin inhibitors
1996
The Toxicogenomic Multiverse: Convergent Recruitment of Proteins Into Animal Venoms
2009
Mapping Aβ Amyloid Fibril Secondary Structure Using Scanning Proline Mutagenesis
2003
Simulating the dynamics of the primary charge separation process in bacterial photosynthesis
1988 StandoutNobel
Synthesis of Native Proteins by Chemical Ligation
2000
Relevance of the photosynthetic reaction center from purple bacteria to the structure of photosystem II
1988 StandoutNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Crystal Structure of DNA Photolyase from Escherichia coli
1995 StandoutScienceNobel
Organic Chemistry on Solid Supports
1996
Structure-based discovery of β 2 -adrenergic receptor ligands
2009 StandoutNobel
Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation
2004 StandoutNobel
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Organische Chemie an fester Phase
1996
Examining methods for calculations of binding free energies: LRA, LIE, PDLD-LRA, and PDLD/S-LRA calculations of ligands binding to an HIV protease
2000 StandoutNobel
Protein Control of Redox Potentials of Iron−Sulfur Proteins
1996 StandoutNobel
Structural homology of reaction centers from Rhodopseudomonas sphaeroides and Rhodopseudomonas viridis as determined by x-ray diffraction.
1986 StandoutNobel
Single-molecule spectroscopy reveals photosynthetic LH2 complexes switch between emissive states
2013 StandoutNobel
Electronic Excitation Transfer in the LH2 Complex ofRhodobacter sphaeroides
1996
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Protein structure-based design of potent orally bioavailable, nonpeptide inhibitors of human immunodeficiency virus protease.
1995
Intramolecular Long-Distance Electron Transfer in Organic Molecules
1988 Science
A role for destabilizing amino acid replacements in light-chain amyloidosis.
1994
Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant reverse transcriptases resistant to other nonnucleoside inhibitors
2004 StandoutNobel
The 3D profile method for identifying fibril-forming segments of proteins
2006 StandoutNobel
Converting conformational changes to electrostatic energy in molecular motors: The energetics of ATP synthase
2003 StandoutNobel
Enzyme millisecond conformational dynamics do not catalyze the chemical step
2009 StandoutNobel
Enzyme Dynamics During Catalysis
2002 Science
Simulation of enzyme reactions using valence bond force fields and other hybrid quantum/classical approaches
1993 StandoutNobel
Design and synthesis of ring-constrained boropeptide thrombin inhibitors
1996
DMP 323, a nonpeptide cyclic urea inhibitor of human immunodeficiency virus (HIV) protease, specifically and persistently blocks intracellular processing of HIV gag polyprotein
1994
Dispersed Polaron Simulations of Electron Transfer in Photosynthetic Reaction Centers
1989 StandoutScienceNobel
Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function
1998 Standout
Observation of a bacteriochlorophyll anion radical during the primary charge separation in a reaction center
1989
The structure of protein-protein recognition sites.
1990
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release
2017 StandoutNobel
Unidirectionality of charge separation in reaction centers of photosynthetic bacteria
1988 StandoutNobel
Femtosecond dynamics of DNA-mediated electron transfer
1999 StandoutNobel
Works of Chong‐Hwan Chang being referenced
Kinetic and Crystallographic Studies of Thrombin with Ac-(D)Phe-Pro-boroArg-OH and Its Lysine, Amidine, Homolysine, and Ornithine Analogs
1995
Flexibility and function in HIV-1 protease
1995
A Molecular Model for Self-Assembly of Amyloid Fibrils: Immunoglobulin Light Chains
1995
Three‐dimensional solution structure of the HIV‐1 protease complexed with DMP323, a novel cyclic urea‐type inhibitor, determined by nuclear magnetic resonance spectroscopy
1996
Solvation studies of DMP323 and A76928 bound to HIV protease: Analysis of water sites using grand canonical Monte Carlo simulations
1998
Analysis of immunoglobulin domain interactions
1988
Unexpected binding mode of tick anticoagulant peptide complexed to bovine factor Xa
1998
Molecular Basis of HIV-1 Protease Drug Resistance: Structural Analysis of Mutant Proteases Complexed with Cyclic Urea Inhibitors
1997
Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450
1996
Counteracting HIV-1 Protease Drug Resistance: Structural Analysis of Mutant Proteases Complexed with XV638 and SD146, Cyclic Urea Amides with Broad Specificities
1998
Structure of Rhodopseudomonas sphaeroides R‐26 reaction center
1986
Rational Design of Potent, Bioavailable, Nonpeptide Cyclic Ureas as HIV Protease Inhibitors
1994 Science
The molecular basis of HIV-1 protease drug resistance
1996
Site-specific and compensatory mutations imply unexpected pathways for proton delivery to the QB binding site of the photosynthetic reaction center.
1993
REGENERATION OF BLUE AND PURPLE MEMBRANES FROM DEIONIZED BLEACHED MEMBRANES OF Halobacterium halobium
1988
Pronounced effect of the solvent of crystallization on the structure of a multi-domain protein
1987