Citation Impact
Citing Papers
Vaccine-delivered HIV envelope inhibits CD4+ T-cell activation, a mechanism for poor HIV vaccine responses
2006 StandoutNobel
Human Immunodeficiency Virus Type 1 Resistance to the Small Molecule Maturation Inhibitor 3- O -(3′,3′-Dimethylsuccinyl)-Betulinic Acid Is Conferred by a Variety of Single Amino Acid Substitutions at the CA-SP1 Cleavage Site in Gag
2006
Reconstitution of the DNA base excision—repair pathway
1994 StandoutNobel
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Synthesis of a novel series of diphenolic chromone derivatives as inhibitors of NO production in LPS-activated RAW264.7 macrophages
2010
Association between presence of HLA-B*5701, HLA-DR7 , and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir
2002 Standout
Use of organic cosmotropic solutes to crystallize flexible proteins: application to T7 RNA polymerase and its complex with the inhibitor T7 lysozyme
1997 StandoutNobel
Crystal Structures of the Bacillus stearothermophilus CCA-Adding Enzyme and Its Complexes with ATP or CTP
2002 StandoutNobel
Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69
1997 StandoutNobel
Natural products: An evolving role in future drug discovery
2011 Standout
Gel Shift and UV Cross-linking Analysis of Tetrahymena Telomerase
1995 StandoutNobel
Structure of the Replicating Complex of a Pol α Family DNA Polymerase
2001 StandoutNobel
Periluminal Distribution of HIV-Binding Target Cells and Gp340 in the Oral, Cervical and Sigmoid/Rectal Mucosae: A Mapping Study
2015 StandoutNobel
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
1998 StandoutNature
Yeast RNA Polymerase II at 5 Å Resolution
1999 StandoutNobel
Mitochondrial toxicity and HIV therapy
2001
Core Structure of gp41 from the HIV Envelope Glycoprotein
1997 Standout
Crystal structure of Thermus aquaticus DNA polymerase
1995 StandoutNatureNobel
New developments in natural products‐based anti‐AIDS research
2006
An exonucleolytic activity of human apurinic/apyrimidinic endonuclease on 3′ mispaired DNA
2002 Nature
The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases
2006 StandoutNobel
Recent progress in the development of coumarin derivatives as potent anti‐HIV agents
2003 Standout
Betulinic acid derivatives as HIV-1 antivirals
2004
Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide Complexes
2003 StandoutNobel
Two conformations of RNA polymerase II revealed by electron crystallography
1997 StandoutNobel
Antibody neutralization and escape by HIV-1
2003 StandoutNature
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Natural products to drugs: natural product-derived compounds in clinical trials
2008 Standout
Synthesis and studies of anticancer properties of lupane-type triterpenoid derivatives containing a cisplatin fragment
2014
Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B‐family polymerases
2007 StandoutNobel
Structure of T7 RNA polymerase complexed to the transcriptional inhibitor T7 lysozyme
1998 StandoutNobel
Synthesis via carbon suboxide and pharmacological activity of coumarin derivatives
1998
Structure of Taq polymerase with DNA at the polymerase active site
1996 StandoutNatureNobel
Insights into Strand Displacement and Processivity from the Crystal Structure of the Protein-Primed DNA Polymerase of Bacteriophage φ29
2004 StandoutNobel
Structural principles for the inhibition of the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates
1998 StandoutNobel
Pharmacological properties of the ubiquitous natural product betulin
2006
Potent Activity of the HIV-1 Maturation Inhibitor Bevirimat in SCID-hu Thy/Liv Mice
2007
Natural products to drugs: natural product derived compounds in clinical trials
2005
Heterologous Epitope-Scaffold Prime∶Boosting Immuno-Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant
2011 StandoutNobel
Two-Dimensional Crystallography of TFIIB– and IIE–RNA Polymerase II Complexes: Implications for Start Site Selection and Initiation Complex Formation
1996 StandoutNobel
Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor
1997 StandoutNatureNobel
DNA Polymerases: Structural Diversity and Common Mechanisms
1999 StandoutNobel
Insights into the Replisome from the Structure of a Ternary Complex of the DNA Polymerase III α-Subunit
2008 StandoutNobel
Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template
2004 StandoutNatureNobel
Antitumor agents 292. Design, synthesis and pharmacological study of S- and O-substituted 7-mercapto- or hydroxy-coumarins and chromones as potent cytotoxic agents
2011
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages
1999 StandoutNobel
Computer Simulation of Liquids
2017 Standout
Postbinding events mediated by human immunodeficiency virus type 1 are sensitive to modifications in the D4-transmembrane linker region of CD4
1996
PA-457: A potent HIV inhibitor that disrupts core condensation by targeting a late step in Gag processing
2003
A facile synthetic route to 2-trifluoromethyl-substituted polyfunctionalized chromenes and chromones
2011
Theoretical Investigation of the Binding Free Energies and Key Substrate-Recognition Components of the Replication Fidelity of Human DNA Polymerase β
2002 StandoutNobel
The mouth: a gateway or a trap for HIV?
2009
Physiochemical, Optical and Biological Activity of Chitosan-Chromone Derivative for Biomedical Applications
2012 Standout
Catalytic Effects of Mutations of Distant Protein Residues in Human DNA Polymerase β: Theory and Experiment
2012 StandoutNobel
Computer Simulation of the Chemical Catalysis of DNA Polymerases: Discriminating between Alternative Nucleotide Insertion Mechanisms for T7 DNA Polymerase
2003 StandoutNobel
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
STRUCTURES OF TERNARY COMPLEXES OF RAT DNA POLYMERASE BETA, A DNA TEMPLATE-PRIMER, AND DDCTP
1994
Picomolar Inhibitors of HIV Reverse Transcriptase Featuring Bicyclic Replacement of a Cyanovinylphenyl Group
2013
Gene-Targeted Mice Lacking the Trex1 (DNase III) 3′→5′ DNA Exonuclease Develop Inflammatory Myocarditis
2004 StandoutNobel
Membrane Fusion and Exocytosis
1999 StandoutNobel
Recent applications of click chemistry in drug discovery
2019
Human Monoclonal Antibodies Specific for Conformation-Sensitive Epitopes of V3 Neutralize Human Immunodeficiency Virus Type 1 Primary Isolates from Various Clades
2002
CD4, CXCR-4, and CCR-5 dependencies for infections by primary patient and laboratory-adapted isolates of human immunodeficiency virus type 1
1997
A Field Guide to Foldamers
2001 Standout
Computer simulations of protein functions: Searching for the molecular origin of the replication fidelity of DNA polymerases
2005 StandoutNobel
The Membrane-Proximal Tryptophan-Rich Region of the HIV Glycoprotein, gp41, Forms a Well-Defined Helix in Dodecylphosphocholine Micelles,
2001
Free-Energy Perturbation Calculations of DNA Destabilization by Base Substitutions: The Effect of Neutral Guanine·Thymine, Adenine·Cytosine and Adenine·Difluorotoluene Mismatches
2000 StandoutNobel
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Reduction of 3‘-azido-3‘-deoxythymidine (AZT) and AZT nucleotides by thiols. Kinetics and product identification.
1994
Anti-Human Immunodeficiency Virus Activity of YK-FH312 (a Betulinic Acid Derivative), a Novel Compound Blocking Viral Maturation
2001
Anti-AIDS Agents. 37. Synthesis and Structure−Activity Relationships of (3‘R,4‘R)-(+)-cis-Khellactone Derivatives as Novel Potent Anti-HIV Agents
1999
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
2020 StandoutNobel
Catalytic Asymmetric Intramolecular [4+2] Cycloaddition of In Situ Generated ortho‐Quinone Methides
2017 StandoutNobel
Dilation of the Human Immunodeficiency Virus–1 Envelope Glycoprotein Fusion Pore Revealed by the Inhibitory Action of a Synthetic Peptide from gp41
1998
Peptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion.
1996
Microwave-assisted solvent-free synthesis of biologically active novel heterocycles from 3-formylchromones
2010
Structures of Ternary Complexes of Rat DNA Polymerase β, a DNA Template-Primer, and ddCTP
1994 Science
Palladium(II)-Catalyzed Enantioselective Aerobic Dialkoxylation of 2-Propenyl Phenols: A Pronounced Effect of Copper Additives on Enantioselectivity
2007
Determinants of CD4 Independence for a Human Immunodeficiency Virus Type 1 Variant Map outside Regions Required for Coreceptor Specificity
1999
On the Interpretation of the Observed Linear Free Energy Relationship in Phosphate Hydrolysis: A Thorough Computational Study of Phosphate Diester Hydrolysis in Solution
2008 StandoutNobel
Elicitation of structure-specific antibodies by epitope scaffolds
2010 StandoutNobel
Works of Chin‐Ho Chen being referenced
Anti-AIDS agents 79. Design, synthesis, molecular modeling and structure–activity relationships of novel dicamphanoyl-2′,2′-dimethyldihydropyranochromone (DCP) analogs as potent anti-HIV agents
2010
Anti-AIDS Agents. 15. Synthesis and Anti-HIV Activity of Dihydroseselins and Related Analogs
1994
DNA Polymerases versus HIV Reverse Transcriptase in AIDS Therapy
1990
Anti-AIDS agents—XXVII. Synthesis and anti-HIV activity of betulinic acid and dihydrobetulinic acid derivatives
1997
The discovery of a class of novel HIV-1 maturation inhibitors and their potential in the therapy of HIV
2005
Discovery of phenylalanine derivatives as potent HIV-1 capsid inhibitors from click chemistry-based compound library
2018
Structural Rearrangements in the Transmembrane Glycoprotein after Receptor Binding
1994
Anti-AIDS agents 88. Anti-HIV conjugates of betulin and betulinic acid with AZT prepared via click chemistry
2012
Optimization of 2,4-diarylanilines as non-nucleoside HIV-1 reverse transcriptase inhibitors
2012
Anti-AIDS Agents. 60. Substituted 3‘R,4‘R-Di-O-(−)-camphanoyl-2‘,2‘-dimethyldihydropyrano[2,3-f]chromone (DCP) Analogues as Potent Anti-HIV Agents
2004
Betulinic Acid and Dihydrobetulinic Acid Derivatives as Potent Anti-HIV Agents
1996
Induction and Characterization of Neutralizing Antibodies against a Human Immunodeficiency Virus Type 1 Primary Isolate
2001
Anti-AIDS Agents 49. Synthesis, Anti-HIV, and Anti-Fusion Activities of IC9564 Analogues Based on Betulinic Acid
2002
Anti-AIDS Agents. 34. Synthesis and Structure−Activity Relationships of Betulin Derivatives as Anti-HIV Agents
1998
Inhibition of Human Immunodeficiency Virus Type 1 Entry by a Binding Domain of Porphyromonas gingivalis Gingipain
2006