Standout Papers
Citation Impact
Citing Papers
Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells
2002 StandoutScienceNobel
Targeting of Diacylglycerol Degradation to M1 Muscarinic Receptors by ß-Arrestins
2007 StandoutScienceNobel
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels
2006 StandoutNobel
A monomeric red fluorescent protein
2002 StandoutNobel
Diffraction-unlimited all-optical imaging and writing with a photochromic GFP
2011 StandoutNatureNobel
Interaction of a Receptor Tyrosine Kinase, EGF-R, with Caveolins
1997
Identification of Triton X-100 Insoluble Membrane Domains in the Yeast Saccharomyces cerevisiae
1996
RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction
2011 StandoutNobel
Immunoisolation of Caveolae with High Affinity Antibody Binding to the Oligomeric Caveolin Cage
1999
Endothelial Nitric Oxide Synthase Is Regulated by Tyrosine Phosphorylation and Interacts with Caveolin-1
1996
Acylation Targets Endothelial Nitric-oxide Synthase to Plasmalemmal Caveolae
1996
Lipid rafts and signal transduction
2000 Standout
Bradykinin Sequesters B2 Bradykinin Receptors and the Receptor-coupled Gα Subunits Gαq and Gαiin Caveolae in DDT1 MF-2 Smooth Muscle Cells
1997
Concentration of MHC class II molecules in lipid rafts facilitates antigen presentation
2000
Src Tyrosine Kinases, Gα Subunits, and H-Ras Share a Common Membrane-anchored Scaffolding Protein, Caveolin
1996
Contribution of the ERK5/MEK5 Pathway to Ras/Raf Signaling and Growth Control
1999
Structure of the Type VI Secretion System Contractile Sheath
2015 StandoutNobel
Endothelial Nitric Oxide Synthase Targeting to Caveolae
1996
Association of p75 with Caveolin and Localization of Neurotrophin-induced Sphingomyelin Hydrolysis to Caveolae
1997
Mechanism of the Calcium-dependent Multimerization of Synaptotagmin VII Mediated by Its First and Second C2 Domains
2001
The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product
1990 StandoutNobel
The changing landscape of atherosclerosis
2021 StandoutNature
G Protein-coupled Receptors Mediate Two Functionally Distinct Pathways of Tyrosine Phosphorylation in Rat 1a Fibroblasts
1997 StandoutNobel
Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains
1998
Caveolin Interacts with Trk A and p75NTR and Regulates Neurotrophin Signaling Pathways
1999
Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK
1994 StandoutNobel
EGF signalling amplification induced by dynamic clustering of EGFR
2004
A Role for Caveolin in Transport of Cholesterol from Endoplasmic Reticulum to Plasma Membrane
1996
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
Localization of Platelet-derived Growth Factor-stimulated Phosphorylation Cascade to Caveolae
1996
Differential Targeting of β-Adrenergic Receptor Subtypes and Adenylyl Cyclase to Cardiomyocyte Caveolae
2000
Co-purification and Direct Interaction of Ras with Caveolin, an Integral Membrane Protein of Caveolae Microdomains
1996
Dynamic Targeting of the Agonist-stimulated m2 Muscarinic Acetylcholine Receptor to Caveolae in Cardiac Myocytes
1997
HIV-1 Genome Nuclear Import Is Mediated by a Central DNA Flap
2000 StandoutNobel
Membrane protein sequestering by ionic protein–lipid interactions
2011 StandoutNatureNobel
Synaptotagmin I is necessary for compensatory synaptic vesicle endocytosis in vivo
2003 Nature
Regulation of β-Adrenergic Receptor Signaling by S-Nitrosylation of G-Protein-Coupled Receptor Kinase 2
2007 StandoutNobel
Caveolins, a Family of Scaffolding Proteins for Organizing “Preassembled Signaling Complexes” at the Plasma Membrane
1998 Standout
Membrane Fusion
2003 StandoutNobel
GFRα-Mediated Localization of RET to Lipid Rafts Is Required for Effective Downstream Signaling, Differentiation, and Neuronal Survival
2000
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Localization and Turnover of Phosphatidylinositol 4,5-Bisphosphate in Caveolin-enriched Membrane Domains
1996
Cholesterol Depletion Delocalizes Phosphatidylinositol Bisphosphate and Inhibits Hormone-stimulated Phosphatidylinositol Turnover
1998
Structure of Detergent-Resistant Membrane Domains: Does Phase Separation Occur in Biological Membranes?
1997
Synaptotagmin: A Ca2+ sensor that triggers exocytosis?
2002
The Recruitment of Raf-1 to Membranes Is Mediated by Direct Interaction with Phosphatidic Acid and Is Independent of Association with Ras
2000
Identification of Peptide and Protein Ligands for the Caveolin-scaffolding Domain
1997
Glycosylation in health and disease
2019
The evolving role of lipid rafts and caveolae in G protein‐coupled receptor signaling: implications for molecular pharmacology
2004
Identification, Sequence, and Expression of an Invertebrate Caveolin Gene Family from the Nematode Caenorhabditis elegans
1997
A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension
2005
MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation
2002 StandoutNatureNobel
Caveolae and caveolins
1996
Direct observation of the nanoscale dynamics of membrane lipids in a living cell
2008 StandoutNatureNobel
Molecular and Cellular Biology of Caveolae
1997
Mechanism of the SDS-resistant Synaptotagmin Clustering Mediated by the Cysteine Cluster at the Interface between the Transmembrane and Spacer Domains
2001
Synaptotagmins: Why So Many?
2002 StandoutNobel
Cholesterol Depletion of Caveolae Causes Hyperactivation of Extracellular Signal-related Kinase (ERK)
1998
Organized Endothelial Cell Surface Signal Transduction in Caveolae Distinct from Glycosylphosphatidylinositol-anchored Protein Microdomains
1997
Synaptobrevin is essential for fast synaptic-vesicle endocytosis
2004 StandoutNobel
Baculovirus-based Expression of Mammalian Caveolin in Sf21 Insect Cells
1996
β2-Adrenergic Receptor Activates Extracellular Signal-regulated Kinases (ERKs) via the Small G Protein Rap1 and the Serine/Threonine Kinase B-Raf
2000
Expression of Caveolin-3 in Skeletal, Cardiac, and Smooth Muscle Cells
1996
Detergent-insoluble glycosphingolipid/cholesterol-rich membrane domains, lipid rafts and caveolae (Review)
1999
Synaptotagmin VII as a Plasma Membrane Ca2+ Sensor in Exocytosis
2001 StandoutNobel
Activity-Dependent IGF-1 Exocytosis Is Controlled by the Ca2+-Sensor Synaptotagmin-10
2011 StandoutNobel
Synaptotagmin 7 splice variants differentially regulate synaptic vesicle recycling
2003
Microdomains of GPI-anchored proteins in living cells revealed by crosslinking
1998 Nature
Membrane Compartmentation Is Required for Efficient T Cell Activation
1998
Deadly Conformations—Protein Misfolding in Prion Disease
1997
GM3-enriched Microdomain Involved in Cell Adhesion and Signal Transduction through Carbohydrate-Carbohydrate Interaction in Mouse Melanoma B16 Cells
1998
Activated Cardiac Adenosine A1 Receptors Translocate Out of Caveolae
2000
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Association of Phosphofructokinase-M with Caveolin-3 in Differentiated Skeletal Myotubes
1997
STED microscopy reveals that synaptotagmin remains clustered after synaptic vesicle exocytosis
2006 StandoutNatureNobel
A Complexin/Synaptotagmin 1 Switch Controls Fast Synaptic Vesicle Exocytosis
2006 StandoutNobel
Cloning of a human cDNA encoding a CDC2-related kinase by complementation of a budding yeast cdc28 mutation.
1991
Requirement of Receptor Internalization for Opioid Stimulation of Mitogen-Activated Protein Kinase: Biochemical and Immunofluorescence Confocal Microscopic Evidence
1999
Examining Synaptotagmin 1 Function in Dense Core Vesicle Exocytosis under Direct Control of Ca2+
2003 StandoutNobel
synaptotagmin mutants reveal essential functions for the C2B domain in Ca2+-triggered fusion and recycling of synaptic vesicles in vivo.
2001
Synaptotagmin 13: Structure and expression of a novel synaptotagmin
2001 StandoutNobel
Functional rafts in cell membranes
1997 StandoutNature
Compartmentalized IgE Receptor–mediated Signal Transduction in Living Cells
1997
Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions*
2001 Standout
Abnormal Vascular Function and Hypertension in Mice Deficient in Estrogen Receptor β
2002 StandoutScienceNobel
Deletion of CASK in mice is lethal and impairs synaptic function
2007 StandoutNobel
Unexpected Ca 2+ -binding properties of synaptotagmin 9
2004 StandoutNobel
Epidermal growth factor receptor activation is localized within low-buoyant density, non-caveolar membrane domains
1999
Myocyte Adrenoceptor Signaling Pathways
2003 StandoutScienceNobel
Compartmentation of G Protein-Coupled Signaling Pathways in Cardiac Myocytes
2001
T Lymphocyte Costimulation Mediated by Reorganization of Membrane Microdomains
1999 Science
A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones
2002 StandoutNobel
Bound simian virus 40 translocates to caveolin-enriched membrane domains, and its entry is inhibited by drugs that selectively disrupt caveolae.
1996
Recombinant Expression of Caveolin-1 in Oncogenically Transformed Cells Abrogates Anchorage-independent Growth
1997
Distribution of a Glycosylphosphatidylinositol-anchored Protein at the Apical Surface of MDCK Cells Examined at a Resolution of <100 Å Using Imaging Fluorescence Resonance Energy Transfer
1998
Stomatin, flotillin-1, and flotillin-2 are major integral proteins of erythrocyte lipid rafts
2001
Phosphoinositides and phosphoinositide-utilizing enzymes in detergent-insoluble lipid domains.
1996
FUNCTIONS OF LIPID RAFTS IN BIOLOGICAL MEMBRANES
1998 Standout
Nongenomic Steroid Action: Controversies, Questions, and Answers
2003
Integration of murine leukemia virus DNA depends on mitosis.
1993
Immunoisolation and partial characterization of endothelial plasmalemmal vesicles (caveolae).
1997 Nobel
A Chinese hamster cell cycle mutant arrested at G2 phase has a temperature-sensitive ubiquitin-activating enzyme, E1.
1988 StandoutNobel
Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.
1995 StandoutNobel
Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling.
1996
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
The Strength of Interaction at the Raf Cysteine-Rich Domain Is a Critical Determinant of Response of Raf to Ras Family Small GTPases
1999
Nongenomic, ER-Mediated Activation of Endothelial Nitric Oxide Synthase:
2000
Transport of Peptide-MHC Class II Complexes in Developing Dendritic Cells
2000 StandoutScienceNobel
Cross Talk Between Interferon-γ and -α/β Signaling Components in Caveolar Membrane Domains
2000 Science
Anatomy and Dynamics of a Supramolecular Membrane Protein Cluster
2007 StandoutScienceNobel
Expression of caveolin-1 and polarized formation of invaginated caveolae in Caco-2 and MDCK II cells
1998
Interaction of Stoned and Synaptotagmin in Synaptic Vesicle Endocytosis
2001
Structure of the recombinant full-length hamster prion protein PrP(29–231): The N terminus is highly flexible
1997 StandoutNobel
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains
1996 StandoutNobel
High-Resolution FRET Microscopy of Cholera Toxin B-Subunit and GPI-anchored Proteins in Cell Plasma Membranes
2000
THE REGULATION AND PHARMACOLOGY OF ENDOTHELIAL NITRIC OXIDE SYNTHASE
2005
Caveolins, Liquid-Ordered Domains, and Signal Transduction
1999
Observing Fcεri Signaling from the Inside of the Mast Cell Membrane
2000
synaptotagminMutants Reveal Essential Functions for the C2B Domain in Ca2+-Triggered Fusion and Recycling of Synaptic VesiclesIn Vivo
2001
COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform
1997 StandoutNobel
Synaptotagmins I and IX function redundantly in regulated exocytosis but not endocytosis in PC12 cells
2007
Recombinant scrapie-like prion protein of 106 amino acids is soluble
1996 StandoutNobel
THE CAVEOLAE MEMBRANE SYSTEM
1998 Standout
The C2B Domain of Synaptotagmin I Is a Ca2+-Binding Module
2001 StandoutNobel
Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors
2000 StandoutNobel
Ligand-induced protease receptor translocation into caveolae: a mechanism for regulating cell surface proteolysis of the tissue factor-dependent coagulation pathway.
1996
Works of Chieko Mineo being referenced
A Vacuolar-Type Proton ATPase Mediates Acidification of Plasmalemmal Vesicles during Potocytosis
1996
Hyposialylated IgG activates endothelial IgG receptor FcγRIIB to promote obesity-induced insulin resistance
2017
Localization of Epidermal Growth Factor-stimulated Ras/Raf-1 Interaction to Caveolae Membrane
1996
Plasma Membrane Estrogen Receptors Are Coupled to Endothelial Nitric-oxide Synthase through Gαi
2001
SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis
2019 Nature
High Density Lipoprotein-induced Endothelial Nitric-oxide Synthase Activation Is Mediated by Akt and MAP Kinases
2003
Synaptotagmin Regulation of Coated Pit Assembly
2000 StandoutNobel
Physical Association with Ras Enhances Activation of Membrane-bound Raf (RafCAAX)
1997
Regulated Migration of Epidermal Growth Factor Receptor from Caveolae
1999
Estrogen Receptor α and Endothelial Nitric Oxide Synthase Are Organized Into a Functional Signaling Module in Caveolae
2000
A detergent-free method for purifying caveolae membrane from tissue culture cells.
1995
Clustered folate receptors deliver 5-methyltetrahydrofolate to cytoplasm of MA104 cells.
1996
Isolation and analysis of a mammalian temperature-sensitive mutant defective in G2 functions
1986