Citation Impact
Citing Papers
Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases
2016 Standout
Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging
2023 Standout
Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer
2013
Berberine induces oxidative DNA damage and impairs homologous recombination repair in ovarian cancer cells to confer increased sensitivity to PARP inhibition
2017
The Pharmacological Potential of Rutin
2016 Standout
Modulation of gut microbiota by berberine and metformin during the treatment of high-fat diet-induced obesity in rats
2015 Standout
Berberine suppresses in vitro migration and invasion of human SCC-4 tongue squamous cancer cells through the inhibitions of FAK, IKK, NF-κB, u-PA and MMP-2 and -9
2009
Anti-cancer natural products isolated from chinese medicinal herbs
2011 Standout
In vivo and in vitro effects of curcumin on head and neck carcinoma: a systematic review
2016
A review on plant-based rutin extraction methods and its pharmacological activities
2013 Standout
Genetic Evidence for Inhibition of Bacterial Division Protein FtsZ by Berberine
2010
An overview on immunoregulatory and anti-inflammatory properties of chrysin and flavonoids substances
2017
Rutin inhibits human leukemia tumor growth in a murine xenograft model in vivo
2011
The Role of Phenolic Compounds in the Fight against Cancer – A Review
2013
Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials
2012 Standout
Galangin induces apoptosis of hepatocellular carcinoma cellsviathe mitochondrial pathway
2010
Curcumin-Mediated HDAC Inhibition Suppresses the DNA Damage Response and Contributes to Increased DNA Damage Sensitivity
2015
Oxidative Stress and Inflammation: What Polyphenols Can Do for Us?
2016 Standout
Berberine induces p53-dependent cell cycle arrest and apoptosis of human osteosarcoma cells by inflicting DNA damage
2009
Phytochemicals in Cancer Treatment: From Preclinical Studies to Clinical Practice
2020 Standout
Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor
2015
Chemopreventive and therapeutic potential of chrysin in cancer: mechanistic perspectives
2015
Prevalence and hazardous impact of pharmaceutical and personal care products and antibiotics in environment: A review on emerging contaminants
2021 Standout
The alkaloid Berberine inhibits the growth of Anoikis-resistant MCF-7 and MDA-MB-231 breast cancer cell lines by inducing cell cycle arrest
2009
Simultaneous delivery of doxorubicin and curcumin encapsulated in liposomes of pegylated RGDK-lipopeptide to tumor vasculature
2013
Targeting Inflammatory Pathways by Flavonoids for Prevention and Treatment of Cancer
2010
Development of novel nanoparticles shelled with heparin for berberine delivery to treat Helicobacter pylori
2010
Marine steroid derived from Acropora formosa enhances mitochondrial-mediated apoptosis in non-small cell lung cancer cells
2016
Emodin inhibits LOVO colorectal cancer cell proliferation via the regulation of the Bcl-2/Bax ratio and cytochrome c
2014
Carbohydrates, volatile and phenolic compounds composition, and antioxidant activity of calabura (Muntingia calabura L.) fruit
2018 Standout
Kaempferol induced apoptosis via endoplasmic reticulum stress and mitochondria‐dependent pathway in human osteosarcoma U‐2 OS cells
2010
Nano based drug delivery systems: recent developments and future prospects
2018 Standout
A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes
2010 Standout
Protective effects of thymoquinone and diallyl sulphide against malathion-induced toxicity in rats
2020
Quercetin nanoparticle complex attenuated diabetic nephropathy via regulating the expression level of ICAM-1 on endothelium
2017
Berberine and Coptidis Rhizoma as novel antineoplastic agents: A review of traditional use and biomedical investigations
2009 Standout
Screening of the Pan-African Natural Product Library Identifies Ixoratannin A-2 and Boldine as Novel HIV-1 Inhibitors
2015 StandoutNobel
Synergistic anticancer effects of curcumin and resveratrol in Hepa1-6 hepatocellular carcinoma cells
2013
Plant derived substances with anti-cancer activity: from folklore to practice
2015
An overview of application of silver nanoparticles for biomaterials in dentistry
2018 Standout
Rutin attenuates cisplatin induced renal inflammation and apoptosis by reducing NFκB, TNF-α and caspase-3 expression in wistar rats
2011
Casticin from Vitex species: a short review on its anticancer and anti-inflammatory properties
2018
Pyroptosis: mechanisms and diseases
2021 Standout
The JAK/STAT signaling pathway: from bench to clinic
2021 Standout
Emodin suppresses Wnt signaling in human colorectal cancer cells SW480 and SW620
2014
Natural product-based nanoformulations for cancer therapy: Opportunities and challenges
2019 Standout
Emodin induces apoptosis of human cervical cancer hela cells via intrinsic mitochondrial and extrinsic death receptor pathway
2013
Co-assembly of doxorubicin and curcumin targeted micelles for synergistic delivery and improving anti-tumor efficacy
2016
Molecular mechanisms underlying chemopreventive potential of curcumin: Current challenges and future perspectives
2016
The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication
2020 Standout
Inhibitory effect of emodin on migration, invasion and metastasis of human breast cancer MDA-MB-231 cells in vitro and in vivo
2014
Molecular and cellular basis of the anticancer activity of the prenylated flavonoid icaritin in hepatocellular carcinoma
2020
Berberine modulates AP-1 activity to suppress HPV transcription and downstream signaling to induce growth arrest and apoptosis in cervical cancer cells
2011
A novel antitubulin agent, DPQZ, induces cell apoptosis in human oral cancer cells through Ras/Raf inhibition and MAP kinases activation
2012
The Molecular Basis for the Pharmacokinetics and Pharmacodynamics of Curcumin and Its Metabolites in Relation to Cancer
2013
The distinct mechanisms of the antitumor activity of emodin in different types of cancer (Review)
2013
Therapeutic potential of nucleic acid‐binding isoquinoline alkaloids: Binding aspects and implications for drug design
2010
Curcumin and Cancer Cells: How Many Ways Can Curry Kill Tumor Cells Selectively?
2009
Involvement of PPARγ in emodin-induced HK-2 cell apoptosis
2014
Emodin-Provoked Oxidative Stress Induces Apoptosis in Human Colon Cancer HCT116 Cells through a p53-Mitochondrial Apoptotic Pathway
2014
Alkaloids: An overview of their antibacterial, antibiotic-enhancing and antivirulence activities
2014 Standout
Plant-derived immunomodulators: an insight on their preclinical evaluation and clinical trials
2015 Standout
A 12-week supplementation with quercetin does not affect natural killer cell activity, granulocyte oxidative burst activity or granulocyte phagocytosis in female human subjects
2010
Inhibition of PI3K/Akt/mTOR pathway by apigenin induces apoptosis and autophagy in hepatocellular carcinoma cells
2018 Standout
Co-treatment of mouse antral follicles with 17β-estradiol interferes with mono-2-ethylhexyl phthalate (MEHP)-induced atresia and altered apoptosis gene expression
2014
Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals
2010 Standout
Skepinone-L, a Novel Potent and Highly Selective Inhibitor of p38 MAP Kinase, Effectively Impairs Platelet Activation and Thrombus Formation
2013 Standout
Emodin suppresses pulmonary metastasis of breast cancer accompanied with decreased macrophage recruitment and M2 polarization in the lungs
2014
Using sulfuramidimidoyl fluorides that undergo sulfur(vi) fluoride exchange for inverse drug discovery
2020 StandoutNobel
Luteolin induces apoptotic cell death via antioxidant activity in human colon cancer cells
2017
Improving effect of a probiotic mixture on memory and learning abilities in d-galactose–treated aging mice
2019
Traditional usages, botany, phytochemistry, pharmacology and toxicology of Polygonum multiflorum Thunb.: A review
2014 Standout
Virtualizing the p-ANAPL Library: A Step towards Drug Discovery from African Medicinal Plants
2014
Gallic acid: a versatile antioxidant with promising therapeutic and industrial applications
2015 Standout
Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review
2020 Standout
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
2018 StandoutNobel
Poly(lactic-co-glycolic acid) nanoparticles for sustained release of allyl isothiocyanate: characterization,in vitrorelease and biological activity
2017
Kaempferol Induces G2/M Cell Cycle Arrest via Checkpoint Kinase 2 and Promotes Apoptosis via Death Receptors in Human Ovarian Carcinoma A2780/CP70 Cells
2018
EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals
2015 Standout
Natural Polyphenols for Prevention and Treatment of Cancer
2016 Standout
Apoptosis: A Target for Anticancer Therapy
2018 Standout
Genistein induces apoptosis in vitro and has antitumor activity against human leukemia HL‐60 cancer cell xenograft growth in vivo
2019
Aloe‐emodin: A review of its pharmacology, toxicity, and pharmacokinetics
2019 Standout
Elaborating the Role of Natural Products-Induced Autophagy in Cancer Treatment: Achievements and Artifacts in the State of the Art
2015
Berberine inhibits WEHI-3 leukemia cells in vivo.
2007
Molecular Mechanisms of the Anti-Obesity and Anti-Diabetic Properties of Flavonoids
2016 Standout
Emodin, aloe-emodin and rhein induced DNA damage and inhibited DNA repair gene expression in SCC-4 human tongue cancer cells.
2010
Kaempferol suppresses cell metastasis via inhibition of the ERK-p38-JNK and AP-1 signaling pathways in U-2 OS human osteosarcoma cells
2013
Role of Human Macrophage Polarization in Inflammation during Infectious Diseases
2018 Standout
Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics
2016 Standout
Silver Nanoparticles Exhibit the Dose-Dependent Anti-Proliferative Effect against Human Squamous Carcinoma Cells Attenuated in the Presence of Berberine
2016
The outer membrane protein Tp92 of Treponema pallidum induces human mononuclear cell death and IL ‐8 secretion
2018
Marine natural products
2018 Standout
Curcumin, an active component of turmeric (Curcuma longa), and its effects on health
2015 Standout
Berberine inhibits Rho GTPases and cell migration at low doses but induces G2 arrest and apoptosis at high doses in human cancer cells
2009
Flavonoids as Potential Anti-Inflammatory Molecules: A Review
2022 Standout
The Role of Oxidative Stress and Antioxidants in Liver Diseases
2015 Standout
Unraveling the Anticancer Effect of Curcumin and Resveratrol
2016
Kaempferol Induces DNA Damage and Inhibits DNA Repair Associated Protein Expressions in Human Promyelocytic Leukemia HL-60 Cells
2015
Roles of NF-κB in Cancer and Inflammatory Diseases and Their Therapeutic Approaches
2016 Standout
Plant Secondary Metabolites as Anticancer Agents: Successes in Clinical Trials and Therapeutic Application
2018 Standout
Kaempferol induces autophagy through AMPK and AKT signaling molecules and causes G2/M arrest via downregulation of CDK1/cyclin B in SK-HEP-1 human hepatic cancer cells
2013
Flavonoids in Cancer and Apoptosis
2018 Standout
Chemo‐preventive and therapeutic effect of the dietary flavonoid kaempferol: A comprehensive review
2018
Curcumin a potent cancer preventive agent: Mechanisms of cancer cell killing
2014
Berberine-targeted miR-21 chemosensitizes oral carcinomas stem cells
2017
Insoluble-Bound Phenolics in Food
2016
Quinones Derived from Plant Secondary Metabolites as Anti-cancer Agents
2013
Integrons and antibiotic resistance genes in water-borne pathogens: threat detection and risk assessment
2019
Kaempferol: A Key Emphasis to Its Anticancer Potential
2019 Standout
The Essential Medicinal Chemistry of Curcumin
2017 Standout
Human regulatory macrophages are potent in suppression of the xenoimmune response via indoleamine‐2,3‐dioxygenase‐involved mechanism(s)
2017
Dietary Flavonoids Luteolin and Quercetin Inhibit Migration and Invasion of Squamous Carcinoma through Reduction of Src/Stat3/S100A7 Signaling
2019
Anthraquinones As Pharmacological Tools and Drugs
2016 Standout
In Vitro and in Vivo Antitumoral Effects of Combinations of Polyphenols, or Polyphenols and Anticancer Drugs: Perspectives on Cancer Treatment
2015
The pleiotropic role of transcription factor STAT3 in oncogenesis and its targeting through natural products for cancer prevention and therapy
2020
Important Flavonoids and Their Role as a Therapeutic Agent
2020 Standout
Works of Chi‐Cheng Lu being referenced
Antitumor effects of emodin on LS1034 human colon cancer cells in vitro and in vivo: Roles of apoptotic cell death and LS1034 tumor xenografts model
2012
Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells
2010
The newly synthesized 2-(3-hydroxy-5-methoxyphenyl)-6,7-methylenedioxyquinolin-4-one triggers cell apoptosis through induction of oxidative stress and upregulation of the p38 MAPK signaling pathway in HL-60 human leukemia cells
2012
Class 1 integrons and plasmid-mediated multiple resistance genes of the Campylobacter species from pediatric patient of a university hospital in Taiwan
2017
Curcumin inhibits human lung large cell carcinoma cancer tumour growth in a murine xenograft model
2010
AKT serine/threonine protein kinase modulates bufalin-triggered intrinsic pathway of apoptosis in CAL 27 human oral cancer cells
2012
Quercetin inhibited murine leukemia WEHI‐3 cells in vivo and promoted immune response
2009
Emodin Induces Apoptotic Death in Murine Myelomonocytic Leukemia WEHI‐3 Cells In Vitro and Enhances Phagocytosis in Leukemia Mice In Vivo
2011
Quercetin facilitates cell death and chemosensitivity through RAGE/PI3K/AKT/mTOR axis in human pancreatic cancer cells
2019
The synthesized 2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-one (CHM-1) promoted G2/M arrest through inhibition of CDK1 and induced apoptosis through the mitochondrial-dependent pathway in CT-26 murine colorectal adenocarcinoma cells
2009
Rutin inhibits the proliferation of murine leukemia WEHI-3 cells in vivo and promotes immune response in vivo
2008
Berberine inhibits human tongue squamous carcinoma cancer tumor growth in a murine xenograft model
2009
ERK-modulated intrinsic signaling and G2/M phase arrest contribute to the induction of apoptotic death by allyl isothiocyanate in MDA-MB-468 human breast adenocarcinoma cells
2012
Curcumin-Induced DNA Damage and Inhibited DNA Repair Genes Expressions in Mouse–Rat Hybrid Retina Ganglion Cells (N18)
2009
YC-1 induces G0/G1phase arrest and mitochondria-dependent apoptosis in cisplatin-resistant human oral cancer CAR cells
2017
Recent progress in natural dietary non-phenolic bioactives on cancers metastasis
2018
Novel quinazoline HMJ‐30 induces U‐2 OS human osteogenic sarcoma cell apoptosis through induction of oxidative stress and up‐regulation of ATM/p53 signaling pathway
2011
Novel Quinazolinone MJ-29 Triggers Endoplasmic Reticulum Stress and Intrinsic Apoptosis in Murine Leukemia WEHI-3 Cells and Inhibits Leukemic Mice
2012
Gallic acid induces G₀/G₁ phase arrest and apoptosis in human leukemia HL-60 cells through inhibiting cyclin D and E, and activating mitochondria-dependent pathway.
2011
Protective Effects of Catechin against Monosodium Urate-Induced Inflammation through the Modulation of NLRP3 Inflammasome Activation
2015
CCY-1a-E2 induces G2/M phase arrest and apoptotic cell death in HL-60 leukemia cells through cyclin-dependent kinase 1 signaling and the mitochondria-dependent caspase pathway
2016
Gallic acid provokes DNA damage and suppresses DNA repair gene expression in human prostate cancer PC‐3 cells
2011
Allyl isothiocyanate inhibits cell metastasis through suppression of the MAPK pathways in epidermal growth factor-stimulated HT29 human colorectal adenocarcinoma cells
2013
Gallic Acid Induces Apoptosis via Caspase-3 and Mitochondrion-Dependent Pathways in Vitro and Suppresses Lung Xenograft Tumor Growth in Vivo
2009
Berberine induces apoptosis in human HSC-3 oral cancer cells via simultaneous activation of the death receptor-mediated and mitochondrial pathway.
2007
(-)-Menthol inhibits WEHI-3 leukemia cells in vitro and in vivo.
2007
Chrysin, a natural and biologically active flavonoid, influences a murine leukemia model in vivo through enhancing populations of T-and B-cells, and promoting macrophage phagocytosis and NK cell cytotoxicity.
2013
Kaempferol induces ATM/p53-mediated death receptor and mitochondrial apoptosis in human umbilical vein endothelial cells
2016
Activations of Both Extrinsic and Intrinsic Pathways in HCT 116 Human Colorectal Cancer Cells Contribute to Apoptosis through p53-Mediated ATM/Fas Signaling byEmilia sonchifoliaExtract, a Folklore Medicinal Plant
2012
Diallyl sulfide attenuates transforming growth factor-β-stimulated pulmonary fibrosis through Nrf2 activation in lung MRC-5 fibroblast
2016
Berberine induced apoptosis via promoting the expression of caspase-8, -9 and -3, apoptosis-inducing factor and endonuclease G in SCC-4 human tongue squamous carcinoma cancer cells.
2009
Bufalin increases sensitivity to AKT/mTOR-induced autophagic cell death in SK-HEP-1 human hepatocellular carcinoma cells
2012
Casticin Induced Apoptosis in A375.S2 Human Melanoma Cells through the Inhibition of NF-κB and Mitochondria-Dependent Pathways In Vitro and Inhibited Human Melanoma Xenografts in a Mouse Model In Vivo
2016
Curcumin-loaded nanoparticles induce apoptotic cell death through regulation of the function of MDR1 and reactive oxygen species in cisplatin-resistant CAR human oral cancer cells
2013
Epigallocatechin gallate sensitizes cisplatin-resistant oral cancer CAR cell apoptosis and autophagy through stimulating AKT/STAT3 pathway and suppressing multidrug resistance 1 signaling
2016
Safrole suppresses murine myelomonocytic leukemia WEHI-3 cellsin vivo, and stimulates macrophage phagocytosis and natural killer cell cytotoxicity in leukemic mice
2011
Curcumin induces apoptosis in human non-small cell lung cancer NCI-H460 cells through ER stress and caspase cascade- and mitochondria-dependent pathways.
2010