Standout Papers

Hepatitis B virus infection 2009 2026 2014 2020 991
  1. Hepatitis B virus infection (2009)
    Yun‐Fan Liaw, Chia‐Ming Chu The Lancet

Citation Impact

Citing Papers

Species Interactions in a Parasite Community Drive Infection Risk in a Wildlife Population
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Evidence for a functional RNA element in the hepatitis C virus core gene
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Mouse models of acute and chronic hepacivirus infection
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Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production
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Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance
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A comprehensive immunization strategy to eliminate transmission of hepatitis B virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP) Part II: immunization of adults.
2006 Standout
Spontaneous seroclearance of hepatitis B seromarkers and subsequent risk of hepatocellular carcinoma
2013
Natural history and prognostic factors for chronic hepatitis type B.
1991
Serum hepatitis B virus RNA levels as an early predictor of hepatitis B envelope antigen seroconversion during treatment with polymerase inhibitors
2014
Long‐term effect of antiviral therapy on disease course after decompensation in patients with hepatitis B virus–related cirrhosis
2015
Lipid nanoparticle technology for therapeutic gene regulation in the liver
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2007
Hepatitis B surface antigen levels: association with 5-year response to peginterferon alfa-2a in hepatitis B e-antigen-negative patients
2012
Care of patients with chronic hepatitis C and HIV co-infection: recommendations from the HIV–HCV International Panel
2002
Improved survival with screening for hepatocellular carcinoma
2000
Chronic hepatitis B in children after e antigen seroclearance: Final report of a 29-year longitudinal study
2006
Cancer Statistics, 2021
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The Effect of Concurrent Human Immunodeficiency Virus Infection on Chronic Hepatitis B: A Study of 150 Homosexual Men
1989
Ultrasound screening and risk factors for death from hepatocellular carcinoma in a high risk group in Taiwan
2001
Serum α-fetoprotein for diagnosis of hepatocellular carcinoma in patients with chronic liver disease: influence of HBsAg and anti-HCV status
2001
Incidence of hepatocellular carcinoma after HBsAg seroclearance in chronic hepatitis B patients: A need for surveillance
2014
Hepatocellular carcinoma
2003 Standout
Treatment predictors of a sustained virologic response in hepatitis B and C
2008
Hepatocellular carcinoma without cirrhosis in the West: epidemiological factors and histopathology of the non-tumorous liver
1999
Interferón en la hepatitis B
2008
Predicting Cirrhosis Risk Based on the Level of Circulating Hepatitis B Viral Load
2006
Hepatitis B Virus Infection — Natural History and Clinical Consequences
2004 Standout
Molecular diagnosis and treatment of drug-resistant hepatitis B virus
2014
American Gastroenterological Association Institute Guideline on the Prevention and Treatment of Hepatitis B Virus Reactivation During Immunosuppressive Drug Therapy
2014
Natural history of hepatitis B
2003
Comparison of Surgical Outcomes for Hepatocellular Carcinoma in Patients With Hepatitis B Versus Hepatitis C: A Western Experience
2000
Durability of Serologic Response After Lamivudine Treatment of Chronic Hepatitis B
2003
On the Role of RNA Amplification in dsRNA-Triggered Gene Silencing
2001 StandoutNobel
Hepatitis B virus-related decompensated liver cirrhosis: Benefits of antiviral therapy
2012
Long-term follow-up of anti-HBe-positive chronic active hepatitis B
1988
Nuclear Export and Import of Human Hepatitis B Virus Capsid Protein and Particles
2010
Clinical trials in primary hepatocellular carcinoma: current status and future directions
1988
Molecular pathogenesis of human hepatocellular carcinoma
2002
Effects of Tenofovir Disoproxil Fumarate in Hepatitis B e Antigen-Positive Patients With Normal Levels of Alanine Aminotransferase and High Levels of Hepatitis B Virus DNA
2014
Parasite interactions in natural populations: insights from longitudinal data
2008
Surveillance for Hepatocellular Carcinoma and Early Diagnosis
2007
Association of Nucleos(t)ide Analogue Therapy With Reduced Risk of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B—A Nationwide Cohort Study
2014
Hepatocellular carcinoma
2018 Standout
Hepatitis C Virus Infection
2001 Standout
Clinical utility of quantitative HBsAg in natural history and nucleos(t)ide analogue treatment of chronic hepatitis B: new trick of old dog
2012
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Survival and prognostic indicators in hepatitis B surface antigen-positive cirrhosis of the liver
1992
Variations of hepatitis B virus core gene sequence in Western patients with chronic hepatitis B virus infection
1997
Incidence of hepatocellular carcinoma in chronic hepatitis B patients receiving nucleos(t)ide therapy: A systematic review
2010
Rising Incidence of Hepatocellular Carcinoma in the United States
1999 Standout
Alternate Translation Occurs within the Core Coding Region of the Hepatitis C Viral Genome
2002
A Dose-Ranging Study of the Efficacy and Tolerability of Entecavir in Lamivudine-Refractory Chronic Hepatitis B Patients
2005
The polymerase L528M mutation cooperates with nucleotide binding-site mutations, increasing hepatitis B virus replication and drug resistance
2001
Efficacy of thymosin α1 in patients with chronic hepatitis B: A randomized, controlled trial
1998
Ribavirin and Interferon Is Effective for Hepatitis C Virus Clearance in Hepatitis B and C Dually Infected Patients
2003
Management of patients with hepatitis B who require immunosuppressive therapy
2013
Hepatitis B viral genotypes: Clinical relevance and molecular characteristics
2002
Precore mutant hepatitis B virus infection and liver disease
1992
Hepatitis C virus infection in mouse hepatoma cells co-expressing human CD81 and Sip-L
2008
Repeated Measurements of Hepatitis B Surface Antigen Identify Carriers of Inactive HBV During Long-term Follow-up
2016
Preserved T-Cell Function in Children and Young Adults With Immune-Tolerant Chronic Hepatitis B
2012
Meta‐analysis: treatment of hepatitis B infection reduces risk of hepatocellular carcinoma
2008
Hepatitis B e Antigen and the Risk of Hepatocellular Carcinoma
2002
The development of cirrhosis in patients with chronic type B hepatitis: A prospective study
1988
Analysis of cost‐effectiveness of different strategies for hepatocellular carcinoma screening in hepatitis B virus carriers
1992
Management of hepatitis B: 2000—Summary of a workshop
2001
Radiofrequency ablation improves prognosis compared with ethanol injection for hepatocellular carcinoma ≤4 cm
2004
Screening for hepatocellular carcinoma
1998
New insight in the pathobiology of hepatitis B virus infection
2012
Asian‐Pacific consensus statement on the management of chronic hepatitis B: An update*
2003
Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2008 update
2008
Hepatitis B virus genotype B is associated with earlier HBeAg seroconversion compared with hepatitis B virus genotype C
2002
Therapy of hepatitis C: Meta-analysis of interferon alfa-2b trials
1997
HBsAg seroclearance in asymptomatic carriers of high endemic areas
2007
Screening for hepatocellular carcinoma
1999
The cost-effectiveness of hepatitis A vaccination in patients with chronic hepatitis C
2000
PREVALENCE OF ANTIBODIES TO HEPATITIS C VIRUS IN ITALIAN PATIENTS WITH HEPATOCELLULAR CARCINOMA
1989 StandoutNobel
Antiviral drug-resistant HBV
2007
Switching from entecavir to PegIFN alfa-2a in patients with HBeAg-positive chronic hepatitis B: A randomised open-label trial (OSST trial)
2014
Efficacy of entecavir treatment for lamivudine‐resistant hepatitis B over 3 years: Histological improvement or entecavir resistance?
2009
The efficacy and safety comparison between tenofovir and entecavir in treatment of chronic hepatitis B and HBV related cirrhosis: A systematic review and Meta-analysis
2016
Hepatocellular carcinoma
2012 Standout
Hepatitis B Virus Reactivation During Successful Treatment of Hepatitis C Virus With Sofosbuvir and Simeprevir: Figure 1.
2015
Entecavir: A New Nucleoside Analog for the Treatment of Chronic Hepatitis B Infection
2006
A longitudinal follow-up of asymptomatic hepatitis B surface antigen-positive chinese children
1988
Pretherapy alanine transaminase level as a determinant for hepatitis B e antigen seroconversion during lamivudine therapy in patients with chronic hepatitis B
1999
Changes in serum albumin during treatment of chronic hepatitis B with lamivudine: effects of response and emergence of drug resistance
2002
THE MOLECULAR BIOLOGY OF HEPATITIS DELTA VIRUS
1995
Chronic hepatitis B
2001
Screening for hepatocellular carcinoma
2005
American Gastroenterological Association Institute Technical Review on Prevention and Treatment of Hepatitis B Virus Reactivation During Immunosuppressive Drug Therapy
2014
Hepatocellular carcinoma
1988
Survival and prognostic factors in 366 patients with compensated cirrhosis type B: a multicenter study
1994
Resistance surveillance in chronic hepatitis B patients treated with adefovir dipivoxil for up to 60 weeks
2002
MUTATION PREVENTING FORMATION OF HEPATITIS B e ANTIGEN IN PATIENTS WITH CHRONIC HEPATITIS B INFECTION
1989
Natural History of Chronic Hepatitis B Virus Infection: What We Knew in 1981 and What We Know in 2005
2006
Hepatitis due to Reactivation of Hepatitis B Virus in Endemic Areas Among Patients With Hepatitis C Treated With Direct-acting Antiviral Agents
2016
The non-bleeding visible vessel versus the sentinel clot: natural history and risk of rebleeding
1993
Lamivudine for Patients with Chronic Hepatitis B and Advanced Liver Disease
2004 Standout
Hepatitis B e antigen-negative chronic hepatitis B
2001
Intrahepatic mononuclear cell populations and MHC antigen expression in patients with chronic hepatitis B: Effect of interferon-α
1994
Genotype C hepatitis B virus infection is associated with an increased risk of hepatocellular carcinoma
2004
HBsAg seroclearance after nucleoside analogue therapy in patients with chronic hepatitis B: clinical outcomes and durability
2013
A controlled trial of human lymphoblastoid interferon in chronic hepatitis B in Italy
1989
Spontaneous clearance of high-titer serum HBV DNA and risk of hepatocellular carcinoma in a Chinese population
2003
Natural and iatrogenic variation in hepatitis B virus
1999
Lymphangiogenesis in development and human disease
2005 StandoutNature
Treatment of chronic hepatitis B
2001
Clinical trial: a phase II, randomized study evaluating the safety, pharmacokinetics and anti‐viral activity of clevudine for 12 weeks in patients with chronic hepatitis B
2008
Acute exacerbations in Chinese patients with chronic hepatitis B virus (HBV) infection
1990
Unusual Multiple Recoding Events Leading to Alternative Forms of Hepatitis C Virus Core Protein from Genotype 1b
2003
Management of Hepatocellular Carcinoma *
2005 Standout
Hepatic arterial embolization in patients with unresectable hepatocellular carcinoma—A randomized controlled trial
1988
Meta–Analysis of Interferon Randomized Trials in the Treatment of Viral Hepatitis C: Effects of Dose and Duration
1996
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
Transcatheter arterial embolization followed by percutaneous ethanol injection in the treatment of hepatocellular carcinoma
1994
Long-term follow-up of chronic hepatitis B patients treated with interferon alfa
1993
Preemptive use of lamivudine reduces hepatitis B exacerbation after allogeneic hematopoietic cell transplantation
2002
Prospective study of early detection of hepatocellular carcinoma in patients with cirrhosis
1990
Occurrence of hepatocellular carcinoma and decompensation in western european patients with cirrhosis type B
1995
A controlled study of therapeutic endoscopy for peptic ulcer with non-bleeding visible vessel
1990
Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures
2004 Standout
Hepatitis B Virus Genotype and DNA Level and Hepatocellular Carcinoma: A Prospective Study in Men
2005
Clinical Management of Hepatocellular Carcinoma. Conclusions of the Barcelona-2000 EASL Conference
2001 Standout
HBsAg seroclearance in chronic hepatitis B in the Chinese: Virological, histological, and clinical aspects
2004
Detection of Type 2–Like T–Helper Cells in Hepatitis C Virus Infection: Implications for Hepatitis C Virus Chronicity
1997
Hepatocellular carcinoma in cirrhosis: Incidence and risk factors
2004 Standout
Management of treatment failure in chronic hepatitis B
2012
Liver Transplantation for the Treatment of Small Hepatocellular Carcinomas in Patients with Cirrhosis
1996 Standout
Factors That Predict Response of Patients With Hepatitis B e Antigen–Positive Chronic Hepatitis B to Peginterferon-Alfa
2009
Predictors of survival in hepatitis B virus related decompensated cirrhosis on tenofovir therapy: An Indian perspective
2013
Polymorphisms Near IL28B and Serologic Response to Peginterferon in HBeAg-Positive Patients With Chronic Hepatitis B
2011
Prevalence and Clinical Correlates of YMDD Variants during Lamivudine Therapy for Patients with Chronic Hepatitis B
2003
Frequency of hepatitis B virus reactivation in cancer patients undergoing cytotoxic chemotherapy: A prospective study of 626 patients with identification of risk factors
2000
Characteristics of patients with dual infection by hepatitis B and C viruses
1998
Evolution of multi-drug resistant hepatitis B virus during sequential therapy
2006
Efficacy of long-term lamivudine monotherapy in patients with hepatitis B e antigen-negative chronic hepatitis B
2000
Long-term continuous entecavir therapy in nucleos(t)ide-naïve chronic hepatitis B patients
2012
Two Alternative Translation Mechanisms Are Responsible for the Expression of the HCV ARFP/F/Core+1 Coding Open Reading Frame
2003
Chronic hepatitis B
2007 Standout
Lymphoblastoid interferon therapy of chronic HBV infection
1987
Extended Lamivudine Treatment in Patients With Chronic Hepatitis B Enhances Hepatitis B E Antigen Seroconversion Rates: Results After 3 Years of Therapy
2001
Effects of entecavir and lamivudine for hepatitis B decompensated cirrhosis: Meta-analysis
2013
Treatment of hepatitis B virus infection with interferon
1991
Slow decline of hepatitis B burden in general population: Results from a population-based survey and longitudinal follow-up study in Taiwan
2015
Peginterferon Is Superior to Nucleos(t)ide Analogues for Prevention of Hepatocellular Carcinoma in Chronic Hepatitis B
2015
The natural history of chronic hepatitis B virus infection #
2009
Peginterferon for the treatment of chronic hepatitis B in the era of nucleos(t)ide analogues
2008
Hepatocellular Carcinoma in Italian Patients with Cirrhosis
1991
Comprehensive analysis of risk factors associating with Hepatitis B virus (HBV) reactivation in cancer patients undergoing cytotoxic chemotherapy
2004
Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells
2013
Long-term efficacy and safety of adefovir dipivoxil for the treatment of hepatitis B e antigen–positive chronic hepatitis B
2008
Prospective Analysis of Risk Factors for Hepatocellular Carcinoma in Patients With Liver Cirrhosis
2003
Chronic hepatitis B: Update 2009 #
2009 Standout
Peginterferon α‐2a (40 kDa): an advance in the treatment of hepatitis B e antigen‐positive chronic hepatitis B
2003
Hepatitis C virus-specific T lymphocyte responses
1995 StandoutNobel
Association between high serum alanine aminotransferase levels and more rapid development and higher rate of incidence of hepatocellular carcinoma in patients with hepatitis C virus-associated cirrhosis
1999
Combination therapy with interferon‐α and ribavirin in patients with dual hepatitis B and hepatitis C virus infection
2005
Optimal management of hepatitis B virus infection – EASL Special Conference
2015
Comparison of anti-HBe-positive and HBe-antigen-positive chronic hepatitis B in France
1994
Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B
2000
Effects of extended lamivudine therapy in Asian patients with chronic hepatitis B
2000
Four years of lamivudine treatment in Chinese patients with chronic hepatitis B
2004
Structural organization of the hepatitis B virus minichromosome
2001
Factors associated with hepatitis B virus DNA breakthrough in patients receiving prolonged lamivudine therapy
2001
Combination therapy with lamivudine and famciclovir for chronic hepatitis B-infected Chinese patients: A viral dynamics study
2000
Comparison of the Efficacy of Lamivudine Plus Adefovir Versus Entecavir in the Treatment of Lamivudine-Resistant Chronic Hepatitis B: A Systematic Review and Meta-Analysis
2013
Management of chronic hepatitis B in childhood: ESPGHAN clinical practice guidelines
2013
Determinants for Sustained Hbeag Response to Lamivudine Therapy
2003
HCV infection, hepatic HLA display and composition of the mononuclear cell inflammatory infiltrate in chronic alcoholic liver disease
1991
Long–Term Beneficial Effect of Interferon Therapy in Patients With Chronic Hepatitis B Virus Infection
1999
Evidence for a new hepatitis C virus antigen encoded in an overlapping reading frame
2001
The HEP-NET B/C co-infection trial: A prospective multicenter study to investigate the efficacy of pegylated interferon-α2b and ribavirin in patients with HBV/HCV co-infection
2008
Comparison of efficacy and renal safety of telbivudine and entecavir in treatment-naive elderly patients with chronic hepatitis B
2015
Generation of Covalently Closed Circular DNA of Hepatitis B Viruses via Intracellular Recycling Is Regulated in a Virus Specific Manner
2010
Acute Exacerbation of Chronic Hepatitis B Virus Infection After Withdrawal of Lamivudine Therapy
2000
Occult hepatitis B virus infection
2006
Outcome of Hepatitis B e Antigen–Negative Chronic Hepatitis B on Long-Term Nucleos(t)ide Analog Therapy Starting With Lamivudine *
2005
Clinical course after stopping lamivudine in chronic hepatitis B patients with lamivudine‐resistant mutants
2004
A randomized trial of ribavirin and interferon-α vs. interferon-α alone in patients with chronic hepatitis C who were non-responders to a previous treatment
1999
Hepatocellular carcinoma
1991
Course of virologic breakthroughs under long-term lamivudine in HBeAg-negative precore mutant HBV liver disease
2002
Interferon therapy in chronic hepatitis C virus infection
1994
Sero-clearance of hepatitis B surface antigen in chronic carriers does not necessarily imply a good prognosis
1998
Hepatitis E Virus and Chronic Hepatitis in Organ-Transplant Recipients
2008 Standout
Sonographic screening for hepatocellular carcinoma in patients with chronic hepatitis or cirrhosis: an evaluation.
1998
Prospective study of screening for hepatocellular carcinoma in Caucasian patients with cirrhosis
1994
Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide
1996 StandoutNobel
A Comparison of Entecavir and Lamivudine for HBeAg-Positive Chronic Hepatitis B
2006
A Retrospective Study on the Significance of Liver Biopsy and Hepatitis B Surface Antigen in Chronic Hepatitis B Infection
2016
Changes of serum hepatitis B virus DNA and aminotransferase levels during the course of chronic hepatitis B virus infection in children
1990
Preemptive lamivudine therapy based on HBV DNA level in HBsAg-positive kidney allograft recipients
2002
Influence of hepatitis B virus genotype on the long-term outcome of chronic hepatitis B in western patients
2002
Prevention of Hepatitis B reactivation in the setting of immunosuppression
2016
Trained immunity in newborn infants of HBV-infected mothers
2015
Adefovir dipivoxil alone or in combination with lamivudine in patients with lamivudine-resistant chronic hepatitis B 1 1The Adefovir Dipivoxil International 461 Study Group includes the following: N. Afdhal (Beth Israel Deaconess Medical Center, Boston, MA); P. Angus (Austin and Repatriation Medical Centre, Melbourne, Australia); Y. Benhamou (Hopital La Pitie Salpetriere, Paris, France); M. Bourliere (Hopital Saint Joseph, Marseille, France); P. Buggisch (Universitaetsklinikum Eppendorf, Department of Medicine, Hamburg, Germany); P. Couzigou (Hopital Haut Leveque, Pessac, France); P. Ducrotte and G. Riachi (Hopital Charles Nicolle, Rouen, France); E. Jenny Heathcote (Toronto Western Hospital, Toronto, Ontario, Canada); H. W. Hann (Jefferson Medical College, Philadelphia, PA); I. Jacobson (New York Presbyterian Hospital, New York, NY); K. Kowdley (University of Washington Hepatology Center, Seattle, WA); P. Marcellin (Hopital Beaujon, Clichy, France); P. Martin (Cedars-Sinai Medical Center, Los Angeles, CA); J. M. Metreau (Centre Hospitalier Universitaire Henri Mondor, Creteil, France); M. G. Peters (University of California, San Francisco, San Francisco, CA); R. Rubin (Piedmont Hospital, Atlanta, GA); S. Sacks (Viridae Clinical Sciences, Inc., Vancouver, Canada); H. Thomas (St. Mary’s Hospital, London, England); C. Trepo (Hopital Hôtel Dieu, Lyon, France); D. Vetter (Hopital Civil, Strasbourg, France); C. L. Brosgart, R. Ebrahimi, J. Fry, C. Gibbs, K. Kleber, J. Rooney, M. Sullivan, P. Vig, C. Westland, M. Wulfsohn, and S. Xiong (Gilead Sciences, Inc., Foster City, CA); D. F. Gray (GlaxoSmithKline, Greenford, Middlesex, England); R. Schilling and V. Ferry (Parexel International, Waltham, MA); and D. Hunt (Covance Laboratories, Princeton, NJ).
2003
Impact of age and gender on risk of hepatocellular carcinoma after hepatitis B surface antigen seroclearance
2017
Hepatitis B virus and hepatitis C virus dual infection
2014
Assessment of Bone Mineral Density in Tenofovir-Treated Patients With Chronic Hepatitis B: Can the Fracture Risk Assessment Tool Identify Those at Greatest Risk?
2014
Peginterferon Alfa-2a Alone, Lamivudine Alone, and the Two in Combination in Patients with HBeAg-Negative Chronic Hepatitis B
2004
High Doses of alpha-Interferon Are Required in Chronic Hepatitis Due to Coinfection With Hepatitis B virus and hepatitis C virus: long term results of a prospective randomized trial
2001
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Bleeding Peptic Ulcer
1994 Standout
Adaptive immunity in HBV infection
2016
Natural history of chronic HBV carriers in northern Italy: Morbidity and mortality after 30 years
2004
Long-term clinical and histological outcomes in patients with spontaneous hepatitis B surface antigen seroclearance
2004
Review article: chronic hepatitis B – anti‐viral or immunomodulatory therapy?
2010
Lymphoblastoid interferon alfa with or without steroid pretreatment in children with chronic hepatitis B: A multicenter controlled trial
1996
Role of serum hepatitis B virus marker quantitation to differentiate natural history phases of HBV infection
2015
Reactivation of hepatitis B virus replication in patients receiving cytotoxic therapy
1991
Targeting the Achilles heel of the hepatitis B virus: a review of current treatments against covalently closed circular DNA
2015 StandoutNobel
The NS5A Protein of Hepatitis C Virus Is a Zinc Metalloprotein
2004 StandoutNobel
A genetically humanized mouse model for hepatitis C virus infection
2011 StandoutNatureNobel
The Risk of Transfusion-Transmitted Viral Infections
1996 Standout
Asian‐Pacific consensus statement on the management of chronic hepatitis B: a 2005 update
2005
Crystal structure of a hepatitis delta virus ribozyme
1998 StandoutNatureNobel
A long-term follow-up study of asymptomatic hepatitis B surface antigen—Positive carriers in montreal
1994
Interferon Alfa-2b Alone or in Combination with Ribavirin as Initial Treatment for Chronic Hepatitis C
1998 Standout
Evolution of Hepatitis B Virus Polymerase Gene Mutations in Hepatitis B E Antigen-Negative Patients Receiving Lamivudine Therapy
2000
Follow-up and indications for liver biopsy in HBeAg-negative chronic hepatitis B virus infection with persistently normal ALT: A systematic review
2012
HBcrAg predicts hepatocellular carcinoma development: An analysis using time-dependent receiver operating characteristics
2016
Prospective Study of Hepatocellular Carcinoma and Liver Cirrhosis in Asymptomatic Chronic Hepatitis B Virus Carriers
1997
Chylous ascites: A collective review
2000 Standout
Hepatocellular Carcinoma
2011 Standout
Natural history of acute and chronic hepatitis B: The role of HBV genotypes and mutants
2017
Carriers of Inactive Hepatitis B Virus Are Still at Risk for Hepatocellular Carcinoma and Liver-Related Death
2010
Hepatitis C: Natural History of a Unique Infection
1995
Entecavir for Treatment of Lamivudine-Refractory, HBeAg-Positive Chronic Hepatitis B
2006
Synthesis and biological evaluation of helioxanthin analogues
2012
Antigenic relevance of F protein in chronic hepatitis C virus infection
2004
HBsAg Seroclearance in Chronic Hepatitis B in Asian Patients: Replicative Level and Risk of Hepatocellular Carcinoma
2008
Lamivudine treatment in patients with severely decompensated cirrhosis due to replicating hepatitis B infection
2000
Sustained response after a 2‐year course of lamivudine treatment of hepatitis B e antigen‐negative chronic hepatitis B
2004
Long-term therapy of chronic hepatitis B with lamivudine
2000
Surveillance programme of cirrhotic patients for early diagnosis and treatment of hepatocellular carcinoma: a cost effectiveness analysis
2001
Natural history of acute hepatitis B surface antigen-positive hepatitis in Greek adults
1987
Phosphorylation and nuclear localization of the hepatitis B virus core protein: significance of serine in the three repeated SPRRR motifs
1995
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
2023 StandoutNobel
Concurrent hepatitis B and C virus infection and risk of hepatocellular carcinoma in cirrhosis. A prospective study
1994
Hepatocellular Carcinoma
2019 Standout
Effects of interferon on intrahepatic human leukocyte antigens and lymphocyte subsets in patients with chronic hepatitis B and C
1991
Antigenic relevance of F protein in chronic hepatitis C virus infection
2004
EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection
2017 Standout
Adding pegylated interferon to entecavir for hepatitis B e antigen–positive chronic hepatitis B: A multicenter randomized trial (ARES study)
2014
AASLD guidelines for treatment of chronic hepatitis B
2015
Short-term prednisone therapy affects aminotransferase activity and hepatitis C virus RNA levels in chronic hepatitis C
1994
Serologic and Clinical Outcomes of 1536 Alaska Natives Chronically Infected with Hepatitis B Virus
2001
Optimal management of chronic hepatitis B patients with treatment failure and antiviral drug resistance
2013
Molecular virology of hepatitis B virus and the development of antiviral drug resistance
2006
Survival in Chronic Hepatitis B
1984
RNA-Dependent Replication and Transcription of Hepatitis Delta Virus RNA Involve Distinct Cellular RNA Polymerases
2000
Limited Hepatitis B Virus Replication Space in the Chronically Hepatitis C Virus-Infected Liver
2014
Prevalence of Antibodies to Hepatitis E Virus in Veterinarians Working with Swine and in Normal Blood Donors in the United States and Other Countries
2002
A Comprehensive Immunization Strategy to Eliminate Transmission of Hepatitis B Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices (ACIP): Part 1: Immunization of Infants, Children, and Adolescents
2005
Comparison of the efficacies of lamivudine versus entecavir in patients with hepatitis B virus‐related decompensated cirrhosis
2011
Clinical, Virologic and Histologic Outcome Following Seroconversion From Hbeag to Anti–Hbe in Chronic Hepatitis Type B
1986
A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen
2004
Cirrhosis and the aetiology of hepatocellular carcinoma
1987
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Interferon alfa-2b treatment of HBeAg negative/serum HBV DNA positive chronic active hepatitis type B
1990
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Hepatic flare after telbivudine withdrawal and efficacy of postpartum antiviral therapy for pregnancies with chronic hepatitis B virus
2016
Hepatocellular Carcinoma
1988
Tenofovir disoproxil fumarate (TDF), emtricitabine/TDF, and entecavir in patients with decompensated chronic hepatitis B liver disease
2010
Discontinuation of oral antivirals in chronic hepatitis B: A systematic review
2016
Prevention of Hepatitis A Through Active or Passive Immunization: Recommendations of the Advisory Committee on Immunization Practices (ACIP)
1999 Standout
Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus
2014 StandoutNobel
Which Patients With Chronic Hepatitis B Virus Infection Will Respond to α–Interferon Therapy? A Statistical Analysis of Predictive Factors
1989
Screening for Hepatitis C Virus Infection in Adolescents and Adults
2020
Inhibition of Hepatitis B Virus Polymerase by Entecavir
2007
Meta‐analysis: oral anti‐viral agents in adults with decompensated hepatitis B virus cirrhosis
2012
New developments in antiviral therapy for chronic hepatitis B
2009
BLEEDING PEPTIC ULCER: SURGICAL THERAPY
1993
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Efficacy and safety of entecavir and/or tenofovir in hepatitis B compensated and decompensated cirrhotic patients in clinical practice
2013
Characterization of the Intracellular Deproteinized Relaxed Circular DNA of Hepatitis B Virus: an Intermediate of Covalently Closed Circular DNA Formation
2007
Incidence of hepatocellular carcinoma in untreated subjects with chronic hepatitis B: a systematic review and meta‐analysis
2016
Replication of Subgenomic Hepatitis C Virus Replicons in Mouse Fibroblasts Is Facilitated by Deletion of Interferon Regulatory Factor 3 and Expression of Liver-Specific MicroRNA 122
2010
Incidence of hepatocellular carcinoma in chronic hepatitis B and C: A prospective study of 251 patients
1995
Spontaneous hepatitis B e antigen to antibody seroconversion and reversion in Chinese patients with chronic hepatitis B virus infection
1987
RNA editing of hepatitis B virus transcripts by activation-induced cytidine deaminase
2013 StandoutNobel
Scalable mRNA and siRNA Lipid Nanoparticle Production Using a Parallelized Microfluidic Device
2021 StandoutNobel
Pathogenic role of hepatitis B virus in hepatitis B surface antigen—negative decompensated cirrhosis
1995
Clinical outcome of HBeAg-negative chronic hepatitis B in relation to virological response to lamivudine
2004
Targeted DNA Mutagenesis for the Cure of Chronic Viral Infections
2012
Towards a small animal model for hepatitis C
2009 StandoutNobel
Antiviral therapy in chronic hepatitis B viral infection during pregnancy: A systematic review and meta‐analysis
2015
No Benefit to Continue Lamivudine Therapy after Emergence of Ymdd Mutations
2004
Antiviral therapy for chronic hepatitis B viral infection in adults: A systematic review and meta‐analysis
2015
Clinical features and treatment efficacy of peginterferon alfa plus ribavirin in chronic hepatitis C patients coinfected with hepatitis B virus
2011
Hepatitis B Reactivation in Patients With Previous Hepatitis B Virus Exposure Undergoing Rituximab-Containing Chemotherapy for Lymphoma: A Prospective Study
2014
The spectrum of HBV/HCV coinfection: epidemiology, clinical characteristics, viralinteractions and management.
2015
The significance of spontaneous hepatitis B e antigen seroconversion in childhood: With special emphasis on the clearance of hepatitis B e antigen before 3 years of age
1995
Telbivudine: a new nucleoside analogue for the treatment of chronic hepatitis B
2005
In Vitro Susceptibilities of Wild-Type or Drug-Resistant Hepatitis B Virus to (−)-β-d-2,6-Diaminopurine Dioxolane and 2′-Fluoro-5-Methyl-β-l-Arabinofuranosyluracil
2001
Spontaneous reactivation of chronic hepatitis B virus infection
1984

Works of Chia‐Ming Chu being referenced

Intrahepatic distribution of hepatitis B surface and core antigens in chronic hepatitis B virus infection
1987
Fulminant hepatic failure in acute hepatitis C: increased risk in chronic carriers of hepatitis B virus
1999
Age‐specific prevalence and significance of hepatitis B e antigen and antibody in chronic hepatitis B virus infection in taiwan: A comparison among asymptomatic carriers, Chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma
1984
Molecular cloning of a defective hepatitis C virus genome from the ascitic fluid of a patient with hepatocellular carcinoma.
1997
Amino acid substitutions in codons 9–11 of hepatitis C virus core protein lead to the synthesis of a short core protein product
2000
Purification and characterization of a naturally processed hepatitis B virus peptide recognized by CD8+ cytotoxic T lymphocytes.
1996
Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy
1999
Hepatitis B Virus-Related Cirrhosis: Natural History and Treatment
2006
Effects of prednisolone pretreatment in interferon alfa therapy for patients with chronic non‐A, non‐B (C) hepatitis
1993
Serial HBV DNA levels in patients with persistently normal transaminase over 10 years following spontaneous HBeAg seroconversion
2011
Relative Roles of HBsAg Seroclearance and Mortality in the Decline of HBsAg Prevalence With Increasing Age
2010
Chronic hepatitis B virus infection acquired in childhood: special emphasis on prognostic and therapeutic implication of delayed HBeAg seroconversion
2006
Prognosis following spontaneous HBsAg seroclearance in chronic hepatitis B patients with or without concurrent infection
2002
Impact of acute hepatitis C virus superinfection in patients with chronic hepatitis B virus infection☆
2004
Displacement of hepatitis B virus by hepatitis C virus as the cause of continuing chronic hepatitis
1994
Hepatitis B virus infection
2009 Standout
Natural course following the onset of cirrhosis in patients with chronic hepatitis B: a long-term follow-up study
2007
Studies on the Composition of the Mononuclear Cell Infiltrates in Liver From Patients With Chronic Active Delta Hepatitis
1989
The role of laparoscopy in the evaluation of ascites of unknown origin
1994
Natural history of hepatitis b e antigen to antibody seroconversion in patients with normal serum aminotransferase levels
2004
Acute hepatitis C virus superinfection followed by spontaneous HBeAg seroconversion and HBsAg elimination
1991
Identification of a novel strain of hepatitis E virus responsible for sporadic acute hepatitis in Taiwan
1998
Prednisolone Priming Enhances Th1 Response and Efficacy of Subsequent Lamivudine Therapy in Patients With Chronic Hepatitis B
2000
Polyadenylation of the mRNA of hepatitis delta virus is dependent on the structure of the nascent RNA and regulated by the small or large delta antigen
1994
Interferon therapy in HBeAg positive chronic hepatitis reduces progression to cirrhosis and hepatocellular carcinoma
2006
Intrahepatic expression of HBcAg in chronic HBV hepatitis: Lessons from molecular biology
1990
G1 phase dependent nuclear localization of relaxed-circular hepatitis B virus DNA and aphidicolin-induced accumulation of covalently closed circular DNA
1998
Comparison of long‐term effects of lymphoblastoid interferon alpha and recombinant interferon alpha‐2a therapy in patients with chronic hepatitis B
2004
Identification of a novel pre‐S2 mutation in a subgroup of chronic carriers with spontaneous clearance of hepatitis B virus surface antigen
2003
Age-Specific Prognosis Following Spontaneous Hepatitis B E Antigen Seroconversion in Chronic Hepatitis B
2009
Predictive Factors for Reactivation of Hepatitis B Following Hepatitis B e Antigen Seroconversion in Chronic Hepatitis B
2007
Hepatitis C virus infection in patients with chronic liver diseases in an endemic area for hepatitis B virus infection
1991
Concurrent hepatitis C virus and hepatitis delta virus superinfection in patients with chronic hepatitis B virus infection
1992
Natural history of chronic hepatitis B virus infection in adults with emphasis on the occurrence of cirrhosis and hepatocellular carcinoma
2000
Different implications of stigmata of recent hemorrhage in gastric and duodenal ulcers
1988
Changes of serum HBV‐DNA in relation to serum transaminase level during acute exacerbation in patients with chronic type B hepatitis
1988
Simultaneous Acute Hepatitis B Virus and Hepatitis C Virus Infection Leading to Fulminant Hepatitis and Subsequent Chronic Hepatitis C
1995
Acute hepatitis delta virus superinfection in patients with liver cirrhosis
1990
Clearance of the original hepatitis B virus YMDD-motif mutants with emergence of distinct lamivudine-resistant mutants during prolonged lamivudine therapy
2000
Natural course after the development of cirrhosis in patients with chronic type B hepatitis: a prospective study
1989
The aetiology of acute hepatitis in Taiwan: Acute hepatitis superimposed on HBsAg carrier state as the main aetiology of acute hepatitis in areas with high HBsAg carrier rate
1988
Spontaneous relapse of hepatitis in inactive HBsAg carriers
2007
Genotype C hepatitis B virus infection is associated with a higher risk of reactivation of hepatitis B and progression to cirrhosis than genotype B: A longitudinal study of hepatitis B e antigen-positive patients with normal aminotransferase levels at baseline
2005
Long‐term outcome of hepatitis B e antigen–negative hepatitis B surface antigen carriers in relation to changes of alanine aminotransferase levels over time†
2009
Incidence and Risk Factors of Progression to Cirrhosis in Inactive Carriers of Hepatitis B Virus
2009
Decreasing Levels of HBsAg Predict HBsAg Seroclearance in Patients With Inactive Chronic Hepatitis B Virus Infection
2011
HLA class I antigen display on hepatocyte membrane in chronic hepatitis B virus infection: Its role in the pathogenesis of chronic type B hepatitis
1988
Long-term outcome after spontaneous HBeAg seroconversion in patients with chronic hepatitis B
2002
Quantitative assessment of hepatitis C virus RNA by polymerase chain reaction and a digoxigenin detection system: comparison with branched DNA assay
1997
Natural History of Chronic Hepatitis B Virus Infection in Taiwan: Studies of Hepatitis B Virus Dna in Serum
1985
Determinants for hepatitis B e antigen clearance in chronic type B hepatitis
1984
Severe clinical rebound upon withdrawal of corticosteroid before interferon therapy: Incidence and risk factors
1996
Incidence, determinants and significance of delayed clearance of serum HBsAg in chronic hepatitis B virus infection: A prospective study
1991
Clinical and Histological Events Preceding Hepatitis B e Antigen Seroconversion in Chronic Type B Hepatitis
1983
Hepatitis B surface antigen seroclearance during chronic HBV infection
2010
Sex Difference in Chronic Hepatitis B Virus Infection: An Appraisal Based on the Status of Hepatitis B e Antigen and Antibody
1983
Hepatocellular carcinoma in noncirrhotic patients. A laparoscopic study of 92 cases in Taiwan
1984
Identification of a Hepatic Factor Capable of Supporting Hepatitis C Virus Replication in a Nonpermissive Cell Line
2001
HLA Class i antigen display on hepatocyte membrane in chronic hepatitis B virus infection: Its role in the pathogenesis of chronic type B hepatitis
1987
Integration of HBV-DNA may not be a prerequisite for the maintenance of the state of malignant transformation
1986
Intrahepatic distribution of hepatitis B surface and core antigens in chronic hepatitis B virus infection
1987
Appearance and persistence of hepatitis A IgM antibody in acute clinical hepatitis A observed in an outbreak
1986
Alpha‐fetoprotein changes in the course of chronic hepatitis: relation to bridging hepatic necrosis and hepatocellular carcinoma
1986
Acute exacerbation in hepatitis B e antigen positive chronic type B hepatitis
1985
Precore Stop Mutant in HBeAg-Positive Patients with Chronic Hepatitis B: Clinical Characteristics and Correlation with the Course of HBeAg-to-Anti-HBe Seroconversion
2002
Changes of serum hepatitis B virus DNA in two types of clinical events preceding spontaneous hepatitis B e antigen seroconversion in chronic type B hepatitis
1987
Acute exacerbation in chronic type B hepatitis: Comparison between HBeAg and antibody-positive patients
1987
Hepatic decompensation associated with hepatitis B e antigen clearance in chronic type B hepatitis
1985
Cellular immune responses in patients with dual infection of hepatitis B and C viruses: Dominant role of hepatitis C virus
1995
Early detection of anti-HCc antibody in acute hepatitis C virus (HCV) by western blot (immunoblot) using a recombinant HCV core protein fragment
1994
Early detection of hepatocellular carcinoma in patients with chronic type B hepatitis
1986
Chronic Lobular Hepatitis: A Clinicopathological and Prognostic Study
1982
The Window Period Between Hepatitis B e Antigen and Antibody in Chronic Type B Hepatitis
1984
Viral Superinfection in Previously Unrecognized Chronic Carriers of Hepatitis B Virus with Superimposed Acute Fulminant versus Nonfulminant Hepatitis
1999
Off-therapy durability of response to entecavir therapy in hepatitis B e antigen-negative chronic hepatitis B patients
2013
Low-Level Viremia and Intracellular Expression of Hepatitis B Surface Antigen (HBsAg) in HBsAg Carriers with Concurrent Hepatitis C Virus Infection
1998
The role of delta superinfection in acute exacerbations of chronic type B hepatitis
1986
Precore mutant of hepatitis B virus prevails in acute and chronic infections in an area in which hepatitis B is endemic
1996
Rankless by CCL
2026