Citation Impact
Citing Papers
On the relationship between folding and chemical landscapes in enzyme catalysis
2008 StandoutNobel
Navigating the protein fitness landscape with Gaussian processes
2012 StandoutNobel
Protein stability promotes evolvability
2006 StandoutNobel
De novo design and directed folding of disulfide-bridged peptide heterodimers
2022 StandoutNobel
Reversible enantioselectivity of enzymatic reactions by media
1991
GROMACS: Fast, flexible, and free
2005 Standout
Dynamic personalities of proteins
2007 StandoutNature
Analysis of the structural stability of the multidomain enzyme flavocytochrome P-450 BM3
1996
A De Novo Protein Binding Pair By Computational Design and Directed Evolution
2011 StandoutNobel
von Willebrand Factor–Cleaving Protease in Thrombotic Thrombocytopenic Purpura and the Hemolytic–Uremic Syndrome
1998 Standout
Over-production of Proteins inEscherichia coli: Mutant Hosts that Allow Synthesis of some Membrane Proteins and Globular Proteins at High Levels
1996 StandoutNobel
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
Kinetic Analysis of the Mechanism and Specificity of Protein-disulfide Isomerase Using Fluorescence-quenched Peptides
1998 StandoutNobel
Computational Enzyme Design
2013 StandoutNobel
Molecular dynamics simulations of N-terminal peptides from a nucleotide binding protein
1996
Translational regulation of proinsulin biosynthesis and proinsulin conversion in the pancreaticβ-cell
2000
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Thermal denaturation of .beta.-galactosidase and of two site specific mutants
1990 StandoutNobel
Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura
2001 StandoutNature
Network antibodies identify nuclear lamin B as a physiological attachment site for peripherin intermediate filaments
1991 StandoutNobel
Conformation of peptide fragments of proteins in aqueous solution: implications for initiation of protein folding
1988
Conditional disorder in chaperone action
2012
Improving enzymes by using them in organic solvents
2001 StandoutNature
The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease.
1996 StandoutNobel
Protein folding in the cell
1992 StandoutNature
Recent Developments in Inhibiting Cysteine and Serine Proteases
1990
Activation-dependent Conformational Changes in β-Arrestin 2
2004 StandoutNobel
Temperature adaptation of enzymes: Lessons from laboratory evolution
2001 StandoutNobel
Protein folding: local structures, domains, subunits, and assemblies
1991
Molecular chaperones in cellular protein folding
1996 StandoutNature
Conformational change of dihydrofolate reductase near the active site after thiol modification: detected by limited proteolysis
2000
Optimizing Protein Stability In Vivo
2009
Cold Adaptation of a Mesophilic Subtilisin-like Protease by Laboratory Evolution
2000 StandoutNobel
Functional properties of the individual thioredoxin-like domains of protein disulfide isomerase
1995
Exploring protein fitness landscapes by directed evolution
2009 StandoutNobel
Stability and stabilization of globular proteins in solution
2000
The mechanism of protein folding. Implications of in vitro refolding models for de novo protein folding and translocation in the cell
1990
Protein folding and molecular chaperones in Archaea
2001
Dissecting the Mechanism of Protein Disulfide Isomerase: Catalysis of Disulfide Bond Formation in a Model Peptide
1994
Why are proteins marginally stable?
2001
Interactions Between Protein Disulphide Isomerase and Peptides
1997
Antibodies to von Willebrand Factor–Cleaving Protease in Acute Thrombotic Thrombocytopenic Purpura
1998 Standout
Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein
1995 StandoutNatureNobel
Engineered Alkane‐Hydroxylating Cytochrome P450BM3 Exhibiting Nativelike Catalytic Properties
2007 StandoutNobel
Exploitation of binding energy for catalysis and design
2009 StandoutNatureNobel
Positive cooperativity in the functioning of molecular chaperone GroEL.
1992 StandoutNobel
Dynamical Contributions to Enzyme Catalysis: Critical Tests of A Popular Hypothesis
2006 StandoutNobel
Prion-inducing domain 2–114 of yeast Sup35 protein transforms in vitro into amyloid-like filaments
1997 StandoutNobel
Synthesis and inhibiting activities of 1-peptidyl-2-haloacetyl hydrazines toward cathepsin B and calpains
1993
Watching proteins fold one molecule at a time
2003
Extreme stability in de novo-designed repeat arrays is determined by unusually stable short-range interactions
2018 StandoutNobel
In the light of directed evolution: Pathways of adaptive protein evolution
2009 StandoutNobel
Apparent NAC Effect in Chorismate Mutase Reflects Electrostatic Transition State Stabilization
2003 StandoutNobel
Bacterial Resistance to β-Lactam Antibiotics: Compelling Opportunism, Compelling Opportunity
2005 Standout
Functional mapping of disease susceptibility loci using cell biology
2006 StandoutNobel
Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast
1991 StandoutScience
Funnel sculpting for in silico assembly of secondary structure elements of proteins
2003 StandoutNobel
Roles of mutation and recombination in the evolution of protein thermodynamics
2002 StandoutNobel
Molecular Matchmakers
1993 StandoutScienceNobel
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
How Much Do Enzymes Really Gain by Restraining Their Reacting Fragments?
2002 StandoutNobel
Molecular Chaperones in the Cytosol: from Nascent Chain to Folded Protein
2002 StandoutScience
Intracellular Functions of N-Linked Glycans
2001 StandoutScience
Enzymatic construction of highly strained carbocycles
2018 StandoutScienceNobel
Folding and association of proteins
1987
Folding of firefly luciferase during translation in a cell-free system.
1994
Catalytic Mechanism and Performance of Computationally Designed Enzymes for Kemp Elimination
2008 StandoutNobel
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Insulin—From its Discovery to the Industrial Synthesis of Modern Insulin Analogues
2017
Identification of a region in segment 1 of gelsolin critical for actin binding.
1990
De Novo Computational Design of Retro-Aldol Enzymes
2008 StandoutScienceNobel
Interleukin 1 beta (IL-1 beta) processing in murine macrophages requires a structurally conserved homologue of human IL-1 beta converting enzyme.
1993
An enzymatic molten globule: Efficient coupling of folding and catalysis
2004
Computational design of a pH-sensitive IgG binding protein
2013 StandoutNobel
Minimizing a binding domain from protein A.
1996
A Perspective on Enzyme Catalysis
2003 Science
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Physiologic cleavage of von Willebrand factor by a plasma protease is dependent on its conformation and requires calcium ion
1996
Critical Analysis of Antibody Catalysis
2000
Works of Chen‐Lu Tsou being referenced
Inactivation precedes overall molecular conformation changes during enzyme denaturation
1995
Enzymes as chaperones and chaperones as enzymes
1998
Kinetics of trypsin inhibition by its specific inhibitors
1989
Folding of the nascent peptide chain into a biologically active protein
1988
The insulin A and B chains contain sufficient structural information to form the native molecule
1991
Activation of chicken liver dihydrofolate reductase in concentrated urea solutions
1995
Comparison of secondary structures of insulin and proinsulin by FTIR
1993
Active Site Flexibility in Enzyme Catalysisa
1998
Formation of enzyme—substrate disulfide linkage during catalysis by protein disulfide isomerase
1991
Chemical synthesis of crystalline bovine insulin: a reminiscence
1995
Sequential unfolding of adenylate kinase during denaturation by guanidine hydrochloride
1996
Conformational Flexibility of Enzyme Active Sites
1993 Science
Location of the active sites of some enzymes in limited and flexible molecular regions
1986
Activation of chicken liver dihydrofolate reductase by urea and guanidine hydrochloride is accompanied by conformational change at the active site
1996
Protein disulfide isomerase is both an enzyme and a chaperone
1993
Conformational and activity changes during guanidine denaturation of d-glyceraldehyde-3-phosphate dehydrogenase
1987