Citation Impact
Citing Papers
Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer
2009 Standout
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
2019 StandoutNobel
In situ click chemistry generation of cyclooxygenase-2 inhibitors
2017 Standout
Cyclooxygenase Isozymes: The Biology of Prostaglandin Synthesis and Inhibition
2004 Standout
Inflammation and Alzheimer's disease
2000 Standout
Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2
1996
Prostaglandin Endoperoxide H Synthases-1 and -2
1996
Neuroinflammation in Parkinson's disease: a target for neuroprotection?
2009 Standout
Control of Oxygenation in Lipoxygenase and Cyclooxygenase Catalysis
2007
Therapeutic potential of resveratrol: the in vivo evidence
2006 Standout
Management of cancer pain
1999 Standout
Spatial Requirements for 15-(R)-Hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic Acid Synthesis within the Cyclooxygenase Active Site of Murine COX-2
2000
FARFAR2: Improved De Novo Rosetta Prediction of Complex Global RNA Folds
2020
Eicosanoid Transcellular Biosynthesis: From Cell-Cell Interactions to in Vivo Tissue Responses
2006
Free radicals, metals and antioxidants in oxidative stress-induced cancer
2006 Standout
Molecular Understanding and Modern Application of Traditional Medicines: Triumphs and Trials
2007 Standout
Platelet-Cancer Interplay: Molecular Mechanisms and New Therapeutic Avenues
2021
Aspirin inhibits human coronary artery endothelial cell proliferation by upregulation of p53
2003
Chemoprevention of familial adenomatous polyposis development in the APCmin mouse model by 1,4-phenylene bis(methylene)selenocyanate
2000
Cyclooxygenase‐2 and its regulation in inflammation
1996
Cyclooxygenase-2 Inhibitors in Tumorigenesis (Part I)
1998
Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators
2008 Standout
Novel Docosatrienes and 17S-Resolvins Generated from Docosahexaenoic Acid in Murine Brain, Human Blood, and Glial Cells
2003 Standout
Cardiovascular Risk Associated with Celecoxib in a Clinical Trial for Colorectal Adenoma Prevention
2005 Standout
The historical analysis of aspirin discovery, its relation to the willow tree and antiproliferative and anticancer potential
2006
Allergic Rhinitis and Its Impact on Asthma
2001 Standout
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
Gastrointestinal Toxicity With Celecoxib vs Nonsteroidal Anti-inflammatory Drugs for Osteoarthritis and Rheumatoid Arthritis
2000 Standout
The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase
1995
Nitric Oxide Trapping of the Tyrosyl Radical of Prostaglandin H Synthase-2 Leads to Tyrosine Iminoxyl Radical and Nitrotyrosine Formation
1997
Cyclooxygenase mechanisms
2000
Deficiency of COX-1 causes natriuresis and enhanced sensitivity to ACE inhibition
2001 StandoutNobel
The Role of Arginine 120 of Human Prostaglandin Endoperoxide H Synthase-2 in the Interaction with Fatty Acid Substrates and Inhibitors
1999
Aspirin Inhibition and Acetylation of the Plant Cytochrome P450, Allene Oxide Synthase, Resembles that of Animal Prostaglandin Endoperoxide H Synthase
1998
The structures of prostaglandin endoperoxide H synthases-1 and -2
2002
Resveratrol Inhibits Cyclooxygenase-2 Transcription and Activity in Phorbol Ester-treated Human Mammary Epithelial Cells
1998 Standout
Cyclooxygenase‐2 modulates cellular growth and promotes tumorigenesis
2003
Regulation of Prostaglandin E2 Biosynthesis by Inducible Membrane-associated Prostaglandin E2 Synthase That Acts in Concert with Cyclooxygenase-2
2000 Standout
Prostaglandin endoperoxide synthases-1 and -2
1995
Cyclo-Oxygenase Isoenzymes
1997
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
2023 Standout
Resolution of inflammation: the beginning programs the end
2005 Standout
Bronchial aspirin challenge causes specific eicosanoid response in aspirin-sensitive asthmatics.
1996
Prostaglandin Endoperoxide H Synthases (Cyclooxygenases)-1 and −2
1996 Standout
Eicosanoids and cancer
2010 Standout
Paradoxical roles of the immune system during cancer development
2006 Standout
Overexpression of Cyclooxygenase-2 Induces Cell Cycle Arrest
1999
Augmented Expression of Cyclooxygenase-2 in Human Atherosclerotic Lesions
1999
Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents
1996 StandoutNature
Molecular characterization of the 5.2 KB isoform of the human cyclooxygenase-1 transcript
1996
2‐Chloroadenosine but not adenosine induces apoptosis in rheumatoid fibroblasts independently of cell surface adenosine receptor signalling
2002 StandoutNobel
Prostaglandin synthase 2
1996 Standout
Cyclooxygenase Inhibitors and the Antiplatelet Effects of Aspirin
2001 Standout
Role of Val509 in Time-dependent Inhibition of Human Prostaglandin H Synthase-2 Cyclooxygenase Activity by Isoform-selective Agents
1996
Involvement of Arginine 120, Glutamate 524, and Tyrosine 355 in the Binding of Arachidonate and 2-Phenylpropionic Acid Inhibitors to the Cyclooxygenase Active Site of Ovine Prostaglandin Endoperoxide H Synthase-1
1996
The in vivo assessment of nimesulide cyclooxygenase-2 selectivity
1999
COX-2 inhibitors
1999 Standout
Inflammation, reproduction, cancer and all that…. The regulation and role of the inducible prostaglandin synthase
1995
Accurate prediction of protein–nucleic acid complexes using RoseTTAFoldNA
2023 StandoutNobel
Cyclooxygenases in cancer: progress and perspective
2004
Prostaglandin Endoperoxide H Synthase-1
2001
RASSF tumor suppressor gene family: Biological functions and regulation
2014
New tools provide a second look at HDV ribozyme structure, dynamics and cleavage
2014 StandoutNobel
Arginine 120 of Prostaglandin G/H Synthase-1 Is Required for the Inhibition by Nonsteroidal Anti-inflammatory Drugs Containing a Carboxylic Acid Moiety
1995
Control of Prostaglandin Stereochemistry at the 15-Carbon by Cyclooxygenases-1 and -2
2002
Differential Metabolism of Arachidonic Acid in Nasal Polyp Epithelial Cells Cultured from Aspirin-sensitive and Aspirin-tolerant Patients
2000
E-Prostanoid-3 Receptors Mediate the Proinflammatory Actions of Prostaglandin E2 in Acute Cutaneous Inflammation
2004 StandoutNobel
Amino Acid Determinants in Cyclooxygenase-2 Oxygenation of the Endocannabinoid Anandamide
2003
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
The origin of 15 R -prostaglandins in the Caribbean coral Plexaura homomalla : Molecular cloning and expression of a novel cyclooxygenase
2001
Structural and Functional Basis of Cyclooxygenase Inhibition
2007
Cyclooxygenases: Structural, Cellular, and Molecular Biology
2000 Standout
The Productive Conformation of Arachidonic Acid Bound to Prostaglandin Synthase
2000 Science
Endocrine and Paracrine Regulation of Birth at Term and Preterm*
2000 Standout
Substitution of Tyrosine for the Proximal Histidine Ligand to the Heme of Prostaglandin Endoperoxide Synthase 2: Implications for the Mechanism of Cyclooxygenase Activation and Catalysis
2000
Inhibitor-Induced Changes in the Intrinsic Fluorescence of Human Cyclooxygenase-2
1996
Kinetic basis for selective inhibition of cyclo-oxygenases
1999
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Lipidomics of polyunsaturated-fatty-acid-derived oxygenated metabolites
2011
NAMD2: Greater Scalability for Parallel Molecular Dynamics
1999 Standout
The Cyclooxygenase Reaction Mechanism
2002
Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases
2014 Standout
CYCLOOXYGENASES 1 AND 2
1998 StandoutNobel
Cyclooxygenase in biology and disease
1998 Standout
Arachidonic Acid Oxygenation by COX-1 and COX-2
1999
Identification of Mechanism-Based Inactivation in P450-Catalyzed Cyclopropanation Facilitates Engineering of Improved Enzymes
2016 StandoutNobel
Selective COX-2 Inhibition Improves Endothelial Function in Coronary Artery Disease
2003
Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
2014 Standout
Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions.
1995
Heme-Containing Oxygenases
1996 Standout
Prostaglandins and Inflammation
2011 Standout
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
2001 StandoutNobel
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Prostaglandin endoperoxide synthase: why two isoforms?
1996
Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed in the United States
2011
Organoselenium and Organotellurium Compounds: Toxicology and Pharmacology
2004 Standout
Hormonal Modulation of Plant Immunity
2011 Standout
Mechanism-based inhibition of an aldolase at high concentrations of its natural substrate acetaldehyde: structural insights and protective strategies
2016
Structure and Chemistry of Cytochrome P450
2005 Standout
Works of Chen Ji being referenced
RASSF10 is epigenetically silenced and functions as a tumor suppressor in gastric cancer
2013
Identification of the Catalytic Mg2+ Ion in the Hepatitis Delta Virus Ribozyme
2013
Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction
2015
Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin.
1994