Standout Papers
- Increased Wnt Signaling During Aging Alters Muscle Stem Cell Fate and Increases Fibrosis (2007)
- Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function (2004)
- Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin (2004)
- Virtual Histology of Transgenic Mouse Embryos for High-Throughput Phenotyping (2006)
- New Genetic Tactics to Model Alveolar Rhabdomyosarcoma in the Mouse (2005)
- Practical Vessel Imaging by Computed Tomography in Live Transgenic Mouse Models for Human Tumors (2005)
Citation Impact
Citing Papers
Control of the DNA Damage Checkpoint by Chk1 and Rad53 Protein Kinases Through Distinct Mechanisms
1999 Science
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
2013 StandoutScience
Application of bio-orthogonal proteome labeling to cell transplantation and heterochronic parabiosis
2017
The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage
1998
DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity
2018 StandoutNobel
Distinct fibroblast lineages determine dermal architecture in skin development and repair
2013 StandoutNature
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
2019 StandoutNobel
A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood
2016
Progenitors of skeletal muscle satellite cells express the muscle determination gene, MyoD
2009
Aging, Rejuvenation, and Epigenetic Reprogramming: Resetting the Aging Clock
2012
microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice
2012
MASTR directs MyoD-dependent satellite cell differentiation during skeletal muscle regeneration
2012
Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice
2014
Can we safely target the WNT pathway?
2014
Adult satellite cells and embryonic muscle progenitors have distinct genetic requirements
2009 Nature
Notch1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice
2011
Rejuvenation of Regeneration in the Aging Central Nervous System
2012
Epigenetic regulation of aging stem cells
2011
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
2010 StandoutNature
The genetics of ageing
2010 StandoutNature
Bmpr1a signaling plays critical roles in palatal shelf growth and palatal bone formation
2010
HMGB1/RAGE regulates muscle satellite cell homeostasis via p38 MAPK/myogenin-dependent repression of Pax7 transcription
2012
Hallmarks of aging: An expanding universe
2023 Standout
Maintenance of muscle stem-cell quiescence by microRNA-489
2012 Nature
The p53 family in differentiation and tumorigenesis
2007
The aged niche disrupts muscle stem cell quiescence
2012 Nature
Endothelial Cell Metabolism in Health and Disease
2017
The changing landscape of atherosclerosis
2021 StandoutNature
RAD9 and RAD24 define two additive, interacting branches of the DNA damage checkpoint pathway in budding yeast normally required for Rad53 modification and activation
1998
Poor Repair of Skeletal Muscle in Aging Mice Reflects a Defect in Local, Interleukin-33-Dependent Accumulation of Regulatory T Cells
2016
Reprogramming aging and progeria
2012
NF-κB inhibition delays DNA damage–induced senescence and aging in mice
2012
Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway
1998
Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression
2016
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century
2005 StandoutNobel
Cleft lip and palate: understanding genetic and environmental influences
2011 Standout
Recombinant adenovirus as a methodology for exploration of physiologic functions of growth factor pathways
2007
MicroRNA-1/206 Targets c-Met and Inhibits Rhabdomyosarcoma Development
2009
Metazoan MicroRNAs
2018 Standout
DNA Damage, Aging, and Cancer
2009 Standout
Wnt/β-Catenin Signaling and Disease
2012 Standout
A Temporal Switch from Notch to Wnt Signaling in Muscle Stem Cells Is Necessary for Normal Adult Myogenesis
2008
Heterochronic parabiosis for the study of the effects of aging on stem cells and their niches
2012
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Improved Cutaneous Healing in Diabetic Mice Exposed to Healthy Peripheral Circulation
2009
Short-Term Calorie Restriction Enhances Skeletal Muscle Stem Cell Function
2012
Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human
2012 Standout
Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
2009
Cellular senescence: A link between cancer and age-related degenerative disease?
2011
Integrating Physiological Regulation with Stem Cell and Tissue Homeostasis
2011
Mitotic DNA damage and replication checkpoints in yeast
1998
Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy
2013 Standout
Stems Cells and the Pathways to Aging and Cancer
2008
β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis
2015
Emerging models and paradigms for stem cell ageing
2011
One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
2013 Standout
Age-associated inflammation inhibits epidermal stem cell function
2012
Embryonic and fetal limb myogenic cells are derived from developmentally distinct progenitors and have different requirements for β-catenin
2009
Pro-proliferative and inflammatory signaling converge on FoxO1 transcription factor in pulmonary hypertension
2014 Nobel
Two Cell Lineages, myf5 and myf5-Independent, Participate in Mouse Skeletal Myogenesis
2008 Nobel
Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model
2012
The quest to slow ageing through drug discovery
2020
Regeneration, Rejuvenation, and Replacement: Turning Back the Clock on Tissue Aging
2021
Therapeutic targeting of the angiopoietin–TIE pathway
2017
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
What We Talk About When We Talk About Fat
2014 Standout
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
The role of senescent cells in ageing
2014 StandoutNature
Wnt/β-Catenin Signaling Induces the Aging of Mesenchymal Stem Cells through the DNA Damage Response and the p53/p21 Pathway
2011
Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis
2010
Syndecan-4-Expressing Muscle Progenitor Cells in the SP Engraft as Satellite Cells during Muscle Regeneration
2009
The depletion of skeletal muscle satellite cells with age is concomitant with reduced capacity of single progenitors to produce reserve progeny
2010
The Hallmarks of Aging
2013 Standout
Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA
2010 Standout
Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms
2008
Human DNA Damage Checkpoint Protein hRAD9 Is a 3′ to 5′ Exonuclease
2000 StandoutNobel
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Lineage tracing and genetic ablation of ADAM12+ perivascular cells identify a major source of profibrotic cells during acute tissue injury
2012
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
A Conditional Mouse Model of Synovial Sarcoma: Insights into a Myogenic Origin
2007 StandoutNobel
An elt-3/elt-5/elt-6 GATA Transcription Circuit Guides Aging in C. elegans
2008
Inducible lineage tracing of Pax7‐descendant cells reveals embryonic origin of adult satellite cells
2010
Update on Wnt signaling in bone cell biology and bone disease
2011
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Anemia of Chronic Disease
2005 Standout
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Dissecting racial bias in an algorithm used to manage the health of populations
2019 StandoutScience
Tissue Tregs
2016
Purification and characterization of human DNA damage checkpoint Rad complexes
2001 StandoutNobel
Aging, Cellular Senescence, and Cancer
2012 Standout
Skeletal Muscle Satellite Cells Are Committed to Myogenesis and Do Not Spontaneously Adopt Nonmyogenic Fates
2011
Multiple Sclerosis
2018 Standout
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
2002 StandoutNobel
Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA
2011 StandoutNobel
Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin
2020
An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration
2011
Disease Tolerance as a Defense Strategy
2012 StandoutScience
Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways
2000
Slow-dividing satellite cells retain long-term self-renewal ability in adult muscle
2012
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Augmented Wnt Signaling in a Mammalian Model of Accelerated Aging
2007 Science
Dystrophin‐deficient mdx mice display a reduced life span and are susceptible to spontaneous rhabdomyosarcoma
2007
Canonical Wnt signalling induces satellite-cell proliferation during adult skeletal muscle regeneration
2008
Genomic Expression Responses to DNA-damaging Agents and the Regulatory Role of the Yeast ATR Homolog Mec1p
2001
Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice
2011 StandoutNobel
Satellite Cells and the Muscle Stem Cell Niche
2013 Standout
Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration
2011
Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics
2018 StandoutNobel
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Intradermal adipocytes mediate fibroblast recruitment during skin wound healing
2013
Works of Charles Keller being referenced
Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin
2004 StandoutNobel
Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function
2004 StandoutNobel
Rb1 Gene Inactivation Expands Satellite Cell and Postnatal Myoblast Pools
2011
FOXO1 couples metabolic activity and growth state in the vascular endothelium
2016 Nature
BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration
2009
Sprouty1 Regulates Reversible Quiescence of a Self-Renewing Adult Muscle Stem Cell Pool during Regeneration
2010
Tbx22 null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes
2009
New Genetic Tactics to Model Alveolar Rhabdomyosarcoma in the Mouse
2005 StandoutNobel
Tbx22null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes
2010
Anemia and erythropoietin levels in recipients of solid organ transplants. The Multi-Organ Transplant Group.
1993
Constitutive Notch Activation Upregulates Pax7 and Promotes the Self-Renewal of Skeletal Muscle Satellite Cells
2012
Increased Wnt Signaling During Aging Alters Muscle Stem Cell Fate and Increases Fibrosis
2007 StandoutScience
Reconstitution of a MEC1-Independent Checkpoint in Yeast by Expression of a Novel Human fork head cDNA
1997
Effective fiber hypertrophy in satellite cell-depleted skeletal muscle
2011
Biomarker system for studying muscle, stem cells, and cancer in vivo
2009 Nobel