Citation Impact
Citing Papers
Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells
2008 StandoutScienceNobel
Programmable RNA recognition using a CRISPR-associated Argonaute
2018 StandoutNobel
The physiological and molecular regulation of lipoprotein assembly and secretion
2007
Obesity, adiposity, and dyslipidemia: A consensus statement from the National Lipid Association
2013
Base-modification mRNA editing through deamination — the good, the bad and the unregulated
1996
Lipid and lipoprotein dysregulation in insulin resistant states
2006
Complexity in the Secretory Pathway: The Assembly and Secretion of Apolipoprotein B-containing Lipoproteins
2002
Escherichia coli cytidine deaminase provides a molecular model for ApoB RNA editing and a mechanism for RNA substrate recognition 1 1Edited by A. R. Fersht
1998
Hepatic Very Low Density Lipoprotein-ApoB Overproduction Is Associated with Attenuated Hepatic Insulin Signaling and Overexpression of Protein-tyrosine Phosphatase 1B in a Fructose-fed Hamster Model of Insulin Resistance
2002
SEC14L2 enables pan-genotype HCV replication in cell culture
2015 StandoutNatureNobel
Apolipoprotein B mRNA sequences 3′ of the editing site are necessary and sufficient for editing and editosome assembly
1991
The regulation of ApoB metabolism by insulin
2013
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
2003 StandoutNobel
Mechanisms linking obesity with cardiovascular disease
2006 StandoutNature
In HepG2 Cells, Translocation, Not Degradation, Determines the Fate of the de Novo Synthesized Apolipoprotein B
1995
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
2001 StandoutNature
GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization
2004
Release of ceramide after membrane sphingomyelin hydrolysis decreases the basolateral secretion of triacylglycerol and apolipoprotein B in cultured human intestinal cells.
1993
Autophagy regulates lipid metabolism
2009 StandoutNature
A protein-conducting channel in the endoplasmic reticulum
1991 StandoutNobel
The Degradation of Apolipoprotein B100 Is Mediated by the Ubiquitin-proteasome Pathway and Involves Heat Shock Protein 70
1997 StandoutNobel
RNA editing: Exploring one mode with apolipoprotein B mRNA
1993
Synthesis and secretion of hepatic apolipoprotein B-containing lipoproteins
1994
Targeted Disruption of the Mouse apobec-1 Gene Abolishes Apolipoprotein B mRNA Editing and Eliminates Apolipoprotein B48
1996
Diabetic dyslipidaemia: from basic research to clinical practice*
2003
Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance
2011
Novel Role for RNA-binding Protein CUGBP2 in Mammalian RNA Editing
2001
Abnormal hepatic apolipoprotein B metabolism in type 2 diabetes
2010
Only cytidines 5′ of the apolipoprotein B mRNA mooring sequence are edited
1994
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
2002 StandoutNature
Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production
2004
The low density lipoprotein receptor
1989
Cell and molecular biology of the assembly and secretion of apolipoprotein B-containing lipoproteins by the liver
1999
Evolutionary origins of apoB mRNA editing: Catalysis by a cytidine deaminase that has acquired a novel RNA-binding motif at its active site
1995
Molecular cloning of a human small intestinal apolipoprotein B mRNA editing protein
1994
Editing of glutamate receptor subunit B pre-mRNA in vitro by site-specific deamination of adenosine
1995 StandoutNatureNobel
Ô‖Identification of GRY-RBP as an Apolipoprotein B RNA-binding Protein That Interacts with Both Apobec-1 and Apobec-1 Complementation Factor to Modulate C to U Editing
2001
The Atg18-Atg2 Complex Is Recruited to Autophagic Membranes via Phosphatidylinositol 3-Phosphate and Exerts an Essential Function
2008 StandoutNobel
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
2005 StandoutNature
β-Arrestin1 Mediates Insulin-like Growth Factor 1 (IGF-1) Activation of Phosphatidylinositol 3-Kinase (PI3K) and Anti-apoptosis
2003 StandoutNobel
An Antibody Fragment from a Phage Display Library Competes for Ligand Binding to the Low Density Lipoprotein Receptor Family and Inhibits Rhinovirus Infection
1995 StandoutNobel
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
N-3 fatty acids stimulate intracellular degradation of apoprotein B in rat hepatocytes.
1993
Metabolic Syndrome and Risk of Incident Cardiovascular Events and Death
2007 Standout
Postprandial hypertriglyceridemia as a coronary risk factor
2014
Hyperediting of Multiple Cytidines of Apolipoprotein B mRNA by APOBEC-1 Requires Auxiliary Protein(s) but Not a Mooring Sequence Motif
1996 StandoutNobel
Obesity and dyslipidemia
2003
A place in the world for RNA editing
1995
Cloning of an Apobec-1-binding Protein That Also Interacts with Apolipoprotein B mRNA and Evidence for Its Involvement in RNA Editing
1997
Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B–containing lipoproteins
2008 StandoutNobel
Purification and Molecular Cloning of a Novel Essential Component of the Apolipoprotein B mRNA Editing Enzyme-Complex
2000
HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms
2011
Three distinct RNA sequence elements are required for efficient apolipoprotein B (apoB) RNA editingin vitro
1992
Alternative mRNA Splicing and Differential Promoter Utilization Determine Tissue-specific Expression of the Apolipoprotein B mRNA-editing Protein (Apobec1) Gene in Mice.
1995
Hepatic insulin resistance, metabolic syndrome and cardiovascular disease
2009
Distinct Classes of Phosphatidylinositol 3′-Kinases Are Involved in Signaling Pathways That Control Macroautophagy in HT-29 Cells
2000
Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells
1999 StandoutNobel
Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
2000 StandoutNobel
Insulin regulates hepatic apolipoprotein B production independent of the mass or activity of Akt1/PKBα
2004
Pathophysiology of diabetic dyslipidaemia: where are we?
2015
Apolipoprotein B: Structural and Metabolic Heterogeneity
1983
Carboxy-terminal domain of AID required for its mRNA complex formation in vivo
2009 StandoutNobel
Pathophysiology of Human Visceral Obesity: An Update
2013 Standout
Evolution of intestinal apolipoprotein B mRNA editing. Chicken apolipoprotein B mRNA is not edited, but chicken enterocytes contain in vitro editing enhancement factor(s).
1992
MEK–ERK Inhibition Corrects the Defect in VLDL Assembly in HepG2 Cells
2006
Molecular weights of apoprotein B obtained from human low-density lipoprotein (apoprotein B-PI) and from rat very low density lipoprotein (apoprotein B-PIII)
1985
Fetal Hemoglobin Variants in Mice
1968 StandoutScienceNobel
Purification and characterization of double-stranded RNA adenosine deaminase from bovine nuclear extracts.
1994
Oleate stimulates secretion of apolipoprotein B-containing lipoproteins from Hep G2 cells by inhibiting early intracellular degradation of apolipoprotein B.
1991
The editosome for cytidine to uridine mRNA editing has a native complexity of 27S: identification of intracellular domains containing active and inactive editing factors
2002
Apolipoprotein E synthesis in human kidney, adrenal gland, and liver.
1983
Influence of triacylglycerol biosynthesis rate on the assembly of apoB-100-containing lipoproteins in Hep G2 cells.
1993
Multiple protein domains determine the cell type-specific nuclear distribution of the catalytic subunit required for apolipoprotein B mRNA editing
1997
Tissue-specific, developmental and nutritional regulation of the gene encoding the catalytic subunit of the rat apolipoprotein B mRNA editing enzyme: functional role in the modulation of apoB mRNA editing.
1995
Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals.
1995 StandoutNobel
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
2015 StandoutNobel
Lipid balance in HepG2 cells: active synthesis and impaired mobilization
1994
Molecular Cloning of an Apolipoprotein B Messenger RNA Editing Protein
1993 Science
Membrane proteomics of phagosomes suggests a connection to autophagy
2008 StandoutNobel
Loss of Insulin Signaling in Hepatocytes Leads to Severe Insulin Resistance and Progressive Hepatic Dysfunction
2000
Insulin Inhibits the Maturation Phase of VLDL Assembly via a Phosphoinositide 3-Kinase—Mediated Event
2001
A Receptor-Mediated Pathway for Cholesterol Homeostasis
1986 StandoutScienceNobel
Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling
1998
RNA editing in kinetoplastid protozoa
1997
Apolipoprotein B synthesis by human liver and intestine in vitro.
1986
Induction of RNA editing at heterologous sites by sequences in apolipoprotein B mRNA.
1993
The multifaceted roles of RNA binding in APOBEC cytidine deaminase functions
2014
Functions of Ceramide in Coordinating Cellular Responses to Stress
1996 StandoutScience
The p27 catalytic subunit of the apolipoprotein B mRNA editing enzyme is a cytidine deaminase.
1993
Globin Composition and Synthesis of Hemoglobins in Developing Fetal Mice Erythroid Cells
1967 Science
Pathophysiology of Type 2 Diabetes Mellitus
2020 Standout
Hyperinsulinemia Is Associated With Increased Production Rate of Intestinal Apolipoprotein B-48–Containing Lipoproteins in Humans
2006
apobec-1, the Catalytic Subunit of the Mammalian Apolipoprotein B mRNA Editing Enzyme, Is a Novel RNA-binding Protein
1995
Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management
2011
Proteolysis and lipid-facilitated translocation are distinct but competitive processes that regulate secretion of apolipoprotein B in Hep G2 cells.
1993
A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme.
1997 StandoutNobel
Regulated intracellular degradation of apolipoprotein B in semipermeable HepG2 cells.
1994
Effects of growth hormone on apolipoprotein-B (apoB) messenger ribonucleic acid editing, and apoB 48 and apoB 100 synthesis and secretion in the rat liver.
1992
Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology
1988 StandoutScience
Biosynthesis of Apolipoprotein B48-containing Lipoproteins
1996 StandoutNobel
GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization
2004
Purification of the Xenopus laevis double-stranded RNA adenosine deaminase
1994
Mutational analysis of apolipoprotein B mRNA editing enzyme (APOBEC1): structure–function relationships of RNA editing and dimerization
1999
Cloning and mutagenesis of the rabbit ApoB mRNA editing protein. A zinc motif is essential for catalytic activity, and noncatalytic auxiliary factor(s) of the editing complex are widely distributed.
1994 StandoutNobel
The lipolysis/esterification cycle of hepatic triacylglycerol. Its role in the secretion of very-low-density lipoprotein and its response to hormones and sulphonylureas
1992
Editing of the GLuR-B ion channel RNA in vitro by recombinant double-stranded RNA adenosine deaminase.
1996
Telomerase in kinetoplastid parasitic protozoa
1999 StandoutNobel
Expression and characterization of p27, the catalytic subunit of the apolipoprotein B mRNA editing enzyme.
1994
Regulation of Microsomal Triglyceride Transfer Protein Gene by Insulin in HepG2 Cells
2003
Microsomal triglyceride transfer protein (MTP) regulation in HepG2 cells: insulin negatively regulates MTP gene expression.
1995
Molecular Cloning of Apobec-1 Complementation Factor, a Novel RNA-Binding Protein Involved in the Editing of Apolipoprotein B mRNA
2000
Cloning Human Fetal γ Globin and Mouse α-Type Globin DNA: Characterization and Partial Sequencing
1978 StandoutScienceNobel
The apolipoprotein B gene is constitutively expressed in HepG2 cells: regulation of secretion by oleic acid, albumin, and insulin, and measurement of the mRNA half-life.
1989
Inhibition of Microsomal Triglyceride Transfer Protein Expression and Apolipoprotein B100 Secretion by the Citrus Flavonoid Naringenin and by Insulin Involves Activation of the Mitogen-Activated Protein Kinase Pathway in Hepatocytes
2005
High Energy Phosphates and the Force of Contraction of Cardiac Muscle
1961 StandoutNobel
Dissociation of in vitro DNA deamination activity and physiological functions of AID mutants
2008 StandoutNobel
The Hemoglobins of the Bullfrog, Rana catesbeiana
1974
Cytoplasmic Structure and Contractility in Amoeboid Cells
1979
Induction of RNA Editing at Heterologous Sites by Sequences in Apolipoprotein B mRNA
1993
Characterization of apolipoprotein B mRNA editing from rabbit intestine.
1992
REGULATION OF GLUCOSE PRODUCTION BY THE LIVER
1999
Purification and characterization of a human RNA adenosine deaminase for glutamate receptor B pre-mRNA editing
1997 StandoutNobel
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Internal cell manipulation using infrared laser traps.
1989 StandoutNobel
Expression of human apolipoprotein B100 in transgenic mice. Editing of human apolipoprotein B100 mRNA.
1993
High density lipoprotein metabolism.
1984
Evolution at Two Levels in Humans and Chimpanzees
1975 StandoutScience
Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1
2004 StandoutNobel
Apolipoprotein B mRNA editing is associated with UV crosslinking of proteins to the editing site.
1993
Conformations of Signal Peptides Induced by Lipids Suggest Initial Steps in Protein Export
1986 Science
Structure of the Sec23p/24p and Sec13p/31p complexes of COPII
2001 StandoutNobel
Overproduction of VLDL 1 Driven by Hyperglycemia Is a Dominant Feature of Diabetic Dyslipidemia
2005
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
2016 StandoutNobel
RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells
2003 StandoutNobel
Works of Charles E. Sparks being referenced
Obese Zucker (fa/fa) Rats Are Resistant to Insulin′s Inhibitory Effect on Hepatic APO B Secretion
1994
Effects of fatty acids on apolipoprotein B secretion by McArdle RH-7777 rat hepatoma cells
1997
Regulation of hepatic apolipoprotein B RNA editing in the genetically obese Zucker rat
1996
Acute suppression of apo B secretion by insulin occurs independently of MTP
2011
Insulin regulation of triacylglycerol-rich lipoprotein synthesis and secretion
1994
Effects of nonketotic streptozotocin diabetes on apolipoprotein B synthesis and secretion by primary cultures of rat hepatocytes.
1988
Ethanol Increases Apolipoprotein B mRNA Editing in Rat Primary Hepatocytes and McArdle Cells
1998
Insulin suppression of VLDL apo B secretion is not mediated by the LDL receptor
2002
PI3-kinase activity modulates apo B available for hepatic VLDL production inapobec-1−/−mice
2006
Insulin-dependent apolipoprotein B degradation is mediated by autophagy and involves class I and class III phosphatidylinositide 3-kinases
2013
Elevated HDL is a risk factor for recurrent coronary events in a subgroup of non-diabetic postinfarction patients with hypercholesterolemia and inflammation
2005
Insulin suppression of apolipoprotein B in McArdle RH7777 cells involves increased sortilin 1 interaction and lysosomal targeting
2012
Inflammation reduces HDL protection against primary cardiac risk
2010
Insulin-mediated inhibition of apolipoprotein B secretion requires an intracellular trafficking event and phosphatidylinositol 3-kinase activation: studies with brefeldin A and wortmannin in primary cultures of rat hepatocytes
1996
Liver regrowth and apolipoprotein B secretion by rat hepatocytes following partial hepatectomy
1994
Apolipoprotein B determines risk for recurrent coronary events in postinfarction patients with metabolic syndrome
2004
Phosphoinositide 3-Kinase Activity Is Necessary for Insulin-dependent Inhibition of Apolipoprotein B Secretion by Rat Hepatocytes and Localizes to the Endoplasmic Reticulum
1997
Altered triglyceride-rich lipoprotein production in Zucker diabetic fatty rats
2004
Apolipoprotein B and Lipoprotein Metabolism
1985
Metabolic studies on the arrested and fibrillating perfused heart
1958
Insulin effects on apolipoprotein B production by normal, diabetic and treated-diabetic rat liver and cultured rat hepatocytes
1989
Cholesteryl Ester Transfer Protein Polymorphism (TaqIB) Associates With Risk in Postinfarction Patients With High C-Reactive Protein and High-Density Lipoprotein Cholesterol Levels
2010
A study of hemoglobin differentiation in Rana catesbeiana
1963
Insulin modulation of hepatic synthesis and secretion of apolipoprotein B by rat hepatocytes.
1990
Hepatic and intestinal contribution of two forms of apolipoprotein B to plasma lipoprotein fractions in the rat
1981
PROPERTIES OF APOLIPOPROTEINS AT THE AIR‐WATER INTERFACE *
1980
Insulin effects on apolipoprotein B lipoprotein synthesis and secretion by primary cultures of rat hepatocytes
1986
Plasma Lipoproteins Support Prothrombinase and Other Procoagulant Enzymatic Complexes
1998
Lipoprotein apolipoprotein synthesis by human hepatoma cells in culture
1981
Extract-specific heterogeneity in high-order complexes containing apolipoprotein B mRNA editing activity and RNA-binding proteins.
1993
The role of pancreatic hormones in the regulation of lipid storage, oxidation and secretion in primary cultures of rat hepatocytes. Short- and long-term effects
1992
Secretion of high and low molecular weight phosphorylated apolipoprotein B by hepatocytes from control and diabetic rats. Phosphorylation of APO BH and APO BL.
1988
Selective Hepatic Insulin Resistance, VLDL Overproduction, and Hypertriglyceridemia
2012
An auxiliary factor containing a 240-kDa protein complex is involved in apolipoprotein B RNA editing.
1996
Insulin-Mimetic Effects of Vanadate in Primary Cultures of Rat Hepatocytes
1988
Inhibition of apolipoprotein B net synthesis and secretion from cultured rat hepatocytes by the calcium-channel blocker diltiazem
1989
Hormonal regulation of lipoprotein assembly and secretion
1993
Metabolism of 125I-labeled lipoproteins by the isolated rat lung.
1976
Hepatic Secretion of Lipoproteins in the Rat and the Effect of Experimental Nephrosis
1979
Impaired hepatic apolipoprotein B and E translation in streptozotocin diabetic rats.
1992
Catabolism of the apolipoproteins of HDL in control and nephrotic rats
1981
Glucose-stimulated insulin secretion suppresses hepatic triglyceride-rich lipoprotein and apoB production
2000
In vitro apolipoprotein B mRNA editing: identification of a 27S editing complex.
1991
Extracellular fatty acids are not utilized directly for the synthesis of very-low-density lipoprotein in primary cultures of rat hepatocytes
1992