Citation Impact
Citing Papers
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro
2006 StandoutNobel
Probing mucin-type O-linked glycosylation in living animals
2006 StandoutNobel
Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis
2016 StandoutNobel
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
2005 StandoutScience
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
2015 StandoutNatureNobel
Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection
2011
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism
2009 StandoutNobel
HuR-dependent loading of miRNA RISC to the mRNA encoding the Ras-related small GTPase RhoB controls its translation during UV-induced apoptosis
2011
Pathobiology of hepatic stellate cells
1999
Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy
2004 Standout
MYC on the Path to Cancer
2012 Standout
Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusion
2003
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
2003 StandoutNobel
Rising Incidence of Hepatocellular Carcinoma in the United States
1999 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Vascularized and functional human liver from an iPSC-derived organ bud transplant
2013 StandoutNature
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
Assessment of Chimeric Mice with Humanized Liver as a Tool for Predicting Circulating Human Metabolites
2010
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Liver‐Stage Development ofPlasmodium falciparum,in a Humanized Mouse Model
2006
Hepatitis C virus replication in mice with chimeric human livers
2001
New insight in the pathobiology of hepatitis B virus infection
2012
PREVALENCE OF ANTIBODIES TO HEPATITIS C VIRUS IN ITALIAN PATIENTS WITH HEPATOCELLULAR CARCINOMA
1989 StandoutNobel
Molecular Mechanism of Liver Development and Regeneration
2007
Insights into the Pathobiology of Hepatitis C Virus-Associated Cirrhosis
2002
Repopulation Efficiencies of Adult Hepatocytes, Fetal Liver Progenitor Cells, and Embryonic Stem Cell-Derived Hepatic Cells in Albumin-Promoter-Enhancer Urokinase-Type Plasminogen Activator Mice
2009
Advances in experimental systems to study hepatitis C virus in vitro and in vivo
2015
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors
2002 Standout
Mapping and analysis of chromatin state dynamics in nine human cell types
2011 StandoutNature
Hepatic polyploidy and liver growth control
2000
Genomic imprinting, growth control and the allocation of nutritional resources: consequences for postnatal life
2007
Determinants for Membrane Association of the Hepatitis C Virus RNA-dependent RNA Polymerase
2001 StandoutNobel
Cell-specific expression of hepatocyte growth factor in liver. Upregulation in sinusoidal endothelial cells after carbon tetrachloride.
1993
Chemical remodelling of cell surfaces in living animals
2004 StandoutNatureNobel
Pluripotent stem cell-derived hepatocyte-like cells
2014
Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment
2010
Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice
1989
Hepatocyte Transplantation Activates Hepatic Stellate Cells With Beneficial Modulation of Cell Engraftment in the Rat *
2005
Chimeric mice with humanized liver
2007
A simple and rapid method to determine the zygosity of uPA-transgenic SCID mice
2003
The reconstituted ‘humanized liver’ in TK-NOG mice is mature and functional
2011
The Acetylase/Deacetylase Couple CREB-binding Protein/Sirtuin 1 Controls Hypoxia-inducible Factor 2 Signaling
2012
EMT: 2016
2016 Standout
Delayed liver regeneration with negative regulation of hepatocyte growth factor and positive regulation of transforming growth factor–beta1 mRNA after portal branch ligation in biliary obstructed rats
2002
Activated hepatic stellate cells overexpress p75NTR after partial hepatectomy and undergo apoptosis on nerve growth factor stimulation
2006
Biosynthesis of the reverse transcriptase of hepatitis B viruses involves de novo translational initiation not ribosomal frameshifting
1989 StandoutNatureNobel
Establishment of a humanized model of liver using NOD/Shi-scid IL2Rgnull mice
2008
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
MicroRNAs and Cancer: Short RNAs Go a Long Way
2009
Liver development update: new embryo models, cell lineage control, and morphogenesis
2004
Hepatitis C Virus Entry
2007 StandoutNobel
Sustained survival of human hepatocytes in mice: A model for in vivo infection with human hepatitis B and hepatitis delta viruses
2000
Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis
2011
Characterization of the Oligosaccharides Associated with the Human Ovarian Tumor Marker CA125
2003
Induced pluripotent stem cell–derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice
2010 StandoutNobel
Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction
2003 Nature
AKT/PKB Signaling: Navigating the Network
2017 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
2005 StandoutNature
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
2010 StandoutNature
A genetically humanized mouse model for hepatitis C virus infection
2011 StandoutNatureNobel
NF-κB functions as a tumour promoter in inflammation-associated cancer
2004 StandoutNature
Liver Regeneration after Partial Hepatectomy
2009
Hepatitis B virus structure and biology
1989
Morphological and biochemical characterization of a human liver in a uPA‐SCID mouse chimera†‡
2005
The human liver-uPA-SCID mouse: A model for the evaluation of antiviral compounds against HBV and HCV
2008
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Effect of In Utero and Early-Life Conditions on Adult Health and Disease
2008 Standout
Human and Rat Hepatic Stellate Cells Express Neurotrophins and Neurotrophin Receptors
2001
Replication of hepatitis C virus
2007 StandoutNobel
Rearrangement and enhanced expression of c-myc in hepatocellular carcinoma of hepatitis virus infected woodchucks
1986 Nature
New perspectives on the diversification of theRNA interference system: insights from comparative genomics and smallRNA sequencing
2013
Replication of hepatitis C virus
2000
Correction of factor IX deficiency in mice by embryonic stem cells differentiated in vitro
2005 StandoutNobel
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
Structure, sequence and expression of the hepatitis delta (δ) viral genome
1986 StandoutNatureNobel
Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant.
1995 StandoutNobel
Hepatocellular Carcinoma
1988
A bacterial Argonaute with noncanonical guide RNA specificity
2016 StandoutNobel
Expression of a homologously recombined erythopoietin-SV40 T antigen fusion gene in mouse liver: evidence for erythropoietin production by Ito cells
1994 StandoutNobel
Bipotential Adult Liver Progenitors Are Derived from Chronically Injured Mature Hepatocytes
2014
The hepatitis B virus
1985 Nature
Tissue Engineering--Current Challenges and Expanding Opportunities
2002 StandoutScience
Identification and Characterization of Vitamin A-Storing Cells in Fetal Liver: Implications for Functional Importance of Hepatic Stellate Cells in Liver Development and Hematopoiesis
2007
Transcription of woodchuck hepatitis virus in the chronically infected liver.
1985
Liver Regeneration
1997 StandoutScience
Viruses in Human Cancers
1991 StandoutScienceNobel
Repopulation of adult and neonatal mice with human hepatocytes: A chimeric animal model
2007
Pre-S1 Antigen-Dependent Infection of Tupaia Hepatocyte Cultures with Human Hepatitis B Virus
2003
Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs
2002 StandoutNobel
Genotypic and phenotypic characterization of a putative tumor susceptibility gene, GNMT, in liver cancer.
2003
Insulin-like Growth Factor II Signaling in Neoplastic Proliferation Is Blocked by Transgenic Expression of the Metalloproteinase Inhibitor Timp-1
1999
Towards a small animal model for hepatitis C
2009 StandoutNobel
Cellular Homeostasis and Repair in the Mammalian Liver
2015
The Myc–miR-17∼92 Axis Blunts TGFβ Signaling and Production of Multiple TGFβ-Dependent Antiangiogenic Factors
2010
Confocal microscopy immunofluorescence localization of desmin and other intermediate filament proteins in fetal rat livers
1993
Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication
2004 StandoutNobel
Insulin-Like Growth Factors Stimulate Expression of Hepatocyte Growth Factor But Not Transforming Growth Factor β1 in Cultured Hepatic Stellate Cells*
1997
Works of Charles E. Rogler being referenced
Overexpression of miR-21 Promotes an In vitro Metastatic Phenotype by Targeting the Tumor Suppressor RHOB
2010
cDNA microarray analysis of HBV transgenic mouse liver identifies genes in lipid biosynthetic and growth control pathways affected by HBV
2005
Small RNAs derived from lncRNA RNase MRP have gene-silencing activity relevant to human cartilage–hair hypoplasia
2013
Gene expression pattern in hepatic stem/progenitor cells during rat fetal development using complementary DNA microarrays
2004
Increase in de novo HBV DNA integrations in response to oxidative DNA damage or inhibition of poly(ADP-ribosyl)ation
2002
Elevated Expression of the miR-17–92 Polycistron and miR-21 in Hepadnavirus-Associated Hepatocellular Carcinoma Contributes to the Malignant Phenotype
2008
Cellular and Molecular Mechanisms of Hepatocarcinogenesis
1992
Reactivation of the maternally imprinted IGF2 allele in TGFα induced hepatocellular carcinomas in mice
1998
Identification of hepatocytic and bile ductular cell lineages and candidate stem cells in bipolar ductular reactions in cirrhotic human liver
2007
Genomic expression analysis implicates Wnt signaling pathway and extracellular matrix alterations in hepatic specification and differentiation of murine hepatic stem cells
2001
Hepatic Overexpression of Insulin-like Growth Factor-II in Adulthood Increases Basal and Insulin-stimulated Glucose Disposal in Conscious Mice
1996
Woodchuck hepatocytes remain permissive for hepadnavirus infection and mouse liver repopulation after cryopreservation
2001
Hepatocyte growth factor/hepatopoietin A is expressed in fat-storing cells from rat liver but not myofibroblast-like cells derived from fat-storing cells
1992
Repopulation of Mouse Liver With Human Hepatocytes And In Vivo Infection With Hepatitis B Virus
2001
MicroRNA‐23b cluster microRNAs regulate transforming growth factor‐beta/bone morphogenetic protein signaling and liver stem cell differentiation by targeting Smads†
2009
Molecular aspects of persistent woodchuck hepatitis virus and hepatitis B virus infection and hepatocellular carcinoma
1987
Liver repopulation with xenogenic hepatocytes in B and T cell-deficient mice leads to chronic hepadnavirus infection and clonal growth of hepatocellular carcinoma
1998
Multi-miRNA hairpin method that improves gene knockdown efficiency and provides linked multi-gene knockdown
2006
New evidence for an extra-hepatic role of N-acetylglucosaminyltransferase III in the progression of diethylnitrosamine-induced liver tumors in mice.
2000
Cloning and structural analysis of integrated woodchuck hepatitis virus sequences from hepatocellular carcinomas of woodchucks
1982